Suppression of C-myc Expression Associates with Anti-Proliferation of Aloe-Emodin on Gastric Cancer Cells

REFERENCES

• Lee H. Z., Hsu S. L., Liu M. C., Wu C. H. Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma. Eur J Pharmacol 2001; 431: 287–295
   PubMed Web of Science ®Google Scholar
• Acevedo-Duncan M., Russell C., Patel S., Patel R. Aloe-emodin modulates PKC isozymes, inhibits proliferation, and induces apoptosis in U-373MG glioma cells. Int Immunopharmacol 2004; 4: 1775–1784
   PubMed Web of Science ®Google Scholar
• Pecere T., Gazzola M. V., Mucignat C., Parolin C., Vecchia F. D., Cavaggioni A., Basso G., Diaspro A., Salvato B., Carli M., Palu G. Aloe-emodin is a new type of anticancer agent with selective activity against neuroectodermal tumors. Cancer Res 2000; 60(11)2800–2804
   PubMed Web of Science ®Google Scholar
• Cardenas C., Quesada A. R., Medina M. A. Evaluation of the anti-angiogenic effect of aloe-emodin. Cell Mol Life Sci 2006; 63(24)3083–3089
   PubMed Web of Science ®Google Scholar
• Gallo A., Cha C. Updates on esophageal and gastric cancers. World J Gastroenterol 2006; 12(20)3237–3242
   PubMed Web of Science ®Google Scholar
• Varadhachary G., Ajani J. A. Gastric cancer. Clin Adv Hematol Oncol 2005; 3(2)118–124
   PubMedGoogle Scholar
• Guo J., Xiao B., Zhang S., Liu D., Liao Y., Sun Q. Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. Cancer Biol Ther 2007; 6(1)85–88
   PubMed Web of Science ®Google Scholar
• Chen S. H., Lin K. Y., Chang C. C., Fang C. L., Lin C. P. Aloe-emodin-induced apoptosis in human gastric carcinoma cells. Food Chem Toxicol 2007; 45: 2296–2303
   PubMed Web of Science ®Google Scholar
• Ahmad S., Mineta T., Martuza R. L., Glazer R. I. Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells. Neurosurgery 1994; 5(5)904–909
   Google Scholar
• Shen L., Glazer R. I. Induction of apoptosis in glioblastoma cells by inhibition of protein kinase C and its association with the rapid accumulation of p53 and induction of the insulin-like growth factor-1-binding protein-3. Biochem Pharmacol 1998; 55(10)1711–1719
   PubMed Web of Science ®Google Scholar
• Zeng X., Xu H., Glazer R. I. Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase C alpha. Cancer Res 2002; 62(12)3538–3543
   PubMed Web of Science ®Google Scholar
• Eisenman R. N. Deconstructing myc. Genes Dev 2001; 15(16)2023–2030
   PubMed Web of Science ®Google Scholar
• Flick D. A., Gifford G. E. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor. J Immunol Methods 1984; 68(1–2)167–175
   PubMed Web of Science ®Google Scholar
• Li Z., Zhan W., Wang Z., Zhu B., He Y., Peng J., Cai S., Ma J. Inhibition of PRL-3 gene expression in gastric cancer cell line SGC7901 via microRNA suppressed reduces peritoneal metastasis. Biochem Biophys Res Commun 2006; 248(1)229–237
   Google Scholar
• Liu H. S., Chen C. Y., Lee C. H., Chou Y. I. Selective activation of oncogenic Ha-ras-induced apoptosis in NIH/3T3 cells. Br J Cancer 1998; 77(11)1777–1786
   PubMed Web of Science ®Google Scholar
• Mendoza N., Fong S., Marsters J., Koeppen H., Schwall R., Wickramasinghe D. Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth. Cancer Res 2003; 63(5)1020–1024
   PubMed Web of Science ®Google Scholar
• Jiang H., Luo S., Li H. Cdk5 activator-binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint. J Biol Chem 2005; 280(21)20651–10659
   PubMed Web of Science ®Google Scholar
• Diaz G. D., Paraskeva C., Thomas M. G., Binderup L., Hague A. Apoptosis is induced by the active metabolite of vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy. Cancer Res 2000; 60(8)2304–2312
   PubMed Web of Science ®Google Scholar
• Lin J. G., Chen G. W., Li T. M., Chouh S. T., Tan T. W., Chung J. G. Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway. J Urol 2006; 175(1)343–347
   PubMed Web of Science ®Google Scholar
• Mijatovic S., Maksimovic-Ivanic D., Radovic J., Miljkovic D. J., Harhaji L. J., Vuckvic O., Stosic-Grujicic S., Mostarica Stojkovic M., Trajkovic V. Anti-glioma action of aloe emodin: the role of ERK inhibition. Cell Mol Life Sci 2005; 62(5)589–598
   PubMed Web of Science ®Google Scholar
• Chen H. C., Hsieh W. T., Chang W. C., Chung J. G. Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells. Food Chem Toxicol 2004; 42(8)1251–1257
   PubMed Web of Science ®Google Scholar
• Kuo P. L., Lin T. C., Lin C. C. The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines. Life Sci 2002; 71(16)1879–1892
   PubMed Web of Science ®Google Scholar
• Hanahan D., Weinberg R. A. The hallmarks of cancer. Cell 2000; 100(1)57–70
   PubMed Web of Science ®Google Scholar
• Gourley M., Williamson J. S. Angiogenesis: new targets for the development of anticancer chemotherapies. Curr Pharm Des 2000; 6(4)417–439
   PubMed Web of Science ®Google Scholar
• Xie Z., Zeng X., Waldman T., Glazer R. I. Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 activates β -catenin and c-Myc, and down-regulates caveolin-1. Cancer Res 2003; 63(17)5370–5375
   PubMed Web of Science ®Google Scholar
• Kelley K., Cochran B. H., Stiles C. D., Leder P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell 1983; 35: 603–610, (3 Pt 2)
   PubMed Web of Science ®Google Scholar