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ORIGINAL ARTICLES Clinical Translational Therapeutics

Osteoblastic and Osteolytic Human Osteosarcomas can be Studied With a New Xenograft Mouse Model Producing Spontaneous Metastases

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Pages 435-442 | Published online: 20 Jul 2009

REFERENCES

  • Gatta G., Capocaccia R., Coleman M. P., Ries L. A., Berrino F. Childhood cancer survival in Europe and the United States. Cancer 2002; 95: 1767–1772
  • Howe H. L., Wu X., Ries L. A., Cokkinides V., Ahmed F., Jemal A., Miller A., Williams M., Ward E., Wingo P. A., Ramirez A., Edwards B. K. Annual report to the nation on the status of cancer, 1975–2003, featuring cancer among U.S. Hispanic/Latino populations. Cancer 2006; 107: 1711–1742
  • Link M. P. Adjuvant therapy in the treatment of osteosarcoma. Important Adv. Oncol. 1986; 193–207
  • Belasco J. B., Pritchard J., Malpas J. S., Baker A. R., Kirkpatrick J. A., Ayala A. G., Shuster J. J., Abelson H. T., Simone J. V., Vietti T. T. The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity. N. Engl. J. Med. 1986; 314: 1600–1606
  • Shanley D. J., Mulligan M. E. Osteosarcoma with isolated metastases to the pleura. Pediatr. Radiol. 1991; 21: 226
  • Sandberg A. A., Bridge J. A. Techniques in cancer cytogenetics: an overview and update. Cancer Invest. 1992; 10: 163–172
  • Asai T., Ueda T., Itoh K., Yoshioka K., Aoki Y., Mori S., Yoshikawa H. Establishment and characterization of a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung. Int. J. Cancer 1998; 76: 418–422
  • Dunn T. B., Andervont H. B. Histology of some neoplasms and non-neoplastic lesions found in wild mice maintained under laboratory conditions. J. Natl. Cancer Inst. 1963; 31: 873–901
  • Khanna C., Prehn J., Yeung C., Caylor J., Tsokos M., Helman L. An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential. Clin. Exp. Metastasis 2000; 18: 261–271
  • Martin T. J., Ingleton P. M., Underwood J. C., Michelangeli V. P., Hunt N. H., Melick R. A. Parathyroid hormone-responsive adenylate cyclase in induced transplantable osteogenic rat sarcoma. Nature 1976; 260: 436–438
  • Berlin O., Samid D., Donthineni-Rao R., Akeson W., Amiel D., Woods V. L. Jr. Development of a novel spontaneous metastasis model of human osteosarcoma transplanted orthotopically into bone of athymic mice. Cancer Res. 1993; 53: 4890–4895
  • Chen X., Li Y., Xiong K., Aizicovici S., Xie Y., Zhu Q., Sturtz F., Shulok J., Snodgrass R., Wagner T. E., Platika D. Cancer gene therapy by direct tumor injections of a nonviral T7 vector encoding a thymidine kinase gene. Hum. Gene. Ther. 1998; 9: 729–736
  • Jia S. F., Worth L. L., Kleinerman E. S. A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies. Clin. Exp. Metastasis 1999; 17: 501–506
  • Jones P. A., Rhim J. S., Isaacs H. Jr.; McAllister, R.M. The relationship between tumorigenicity, growth in agar and fibrinolytic activity in a line of human osteosarcoma cells. Int. J. Cancer 1975; 16: 616–621
  • Manara M. C., Baldini N., Serra M., Lollini P. Z., DeGiovanni C., Vaccari M., Argnani A., Benini S., Maurici D., Picci P., Scotlandi K. Reversal of malignant phenotype in human osteosarcoma cells transduced with the alkaline phosphatase gene. Bone 2000; 26: 215–220
  • Dass C. R., Ek E. T., Choong P. F. Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing. J. Cancer Res. Clin. Oncol. 2007; 133: 193–198
  • Ek E. T., Dass C. R., Choong P. F. Commonly used mouse models of osteosarcoma. Crit. Rev. Oncol. Hematol 2006; 60: 1–8
  • Zhou H., Choong P., McCarthy R., Chou S. T., Martin T. J., Ng K. W. In situ hybridization to show sequential expression of osteoblast gene markers during bone formation in vivo. J. Bone Miner. Res. 1994; 9: 1489–1499
  • Ilaslan H., Sundaram M., Unni K. K., Shives T. C. Primary vertebral osteosarcoma: imaging findings. Radiology 2004; 230: 697–702
  • Inwards C. Y., Unni K. K. Classification and grading of bone sarcomas. Hematol. Oncol. Clin. North Am. 1995; 9: 545–569
  • Tebbi C. K., Gaeta J. Osteosarcoma Pediatr. Ann. 1988; 17: 285–300
  • Tsai Y. C., Mendoza A., Mariano J. M., Zhou M., Kostova Z., Chen B., Veenstra T., Hewitt S. M., Helman L. J., Khanna C., Weissman A. M. The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation. Nat. Med. 2007; 13: 1504–1509
  • Khanna C., Wan X., Bose S., Cassaday R., Olomu O., Mendoza A., Yeung C., Gorlick R., Hewitt S. M., Helman L. J. The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. Nat. Med. 2004; 10: 182–186
  • Luu H. H., Kang Q., Park J. K., Si W., Luo Q., Jiang W., Yin H., Montag A. G., Simon M. A., Peabody T. D., Haydon R. C., Rinker-Schaeffer C. W., He T. C. An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis. Clin. Exp. Metastasis 2005; 22: 319–329
  • Luu H. H., Zagaja G. P., Dubauskas Z., Chen S. L., Smith R. C., Watabe K., Ichikawa Y., Ichikawa T., Davis E. M., Le Beau M. M., Rinker-Schaeffer C. W. Identification of a novel metastasis-suppressor region on human chromosome 12. Cancer Res. 1998; 58: 3561–3565
  • Sowa H., Kaji H., Yamaguchi T., Sugimoto T., Chihara K. Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells. J. Biol. Chem. 2002; 277: 36024–36031
  • Sowa H., Kaji H., Yamaguchi T., Sugimoto T., Chihara K. Smad3 promotes alkaline phosphatase activity and mineralization of osteoblastic MC3T3-E1 cells. J. Bone Miner. Res. 2002; 17: 1190–1199
  • Dass C. R., Ek E. T., Contreras K. G., Choong P. F. A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma. Clin. Exp. Metastasis 2006; 23: 367–380
  • Yang S. Y., Yu H., Krygier J. E., Wooley P. H., Mott M. P. High VEGF with rapid growth and early metastasis in a mouse osteosarcoma model. Sarcoma 2007; 2007: 95628
  • Jia S. F., Zhou R. R., Kleinerman E. S. Nude mouse lung metastases models of osteosarcoma and Ewing's sarcoma for evaluating new therapeutic strategies. Methods Mol. Med. 2003; 74: 495–505
  • Tsai Y. C., Mendoza A., Mariano J. M., Zhou M., Kostova Z., Chen Z., Veenstra T., Hewitt S. M., Helman L. J., Khanna C., Weissman A. M. The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation. Nat. Med. 2007; 13: 1504–1509
  • Chirgwin J. M., Guise T. A. Molecular mechanisms of tumor-bone interactions in osteolytic metastases. Crit. Rev. Eukaryot Gene. Expr. 2000; 10: 159–178
  • Giuliani N, Pedrazzoni M., Passeri G., Girasole G. Bisphosphonates inhibit IL-6 production by human osteoblast-like cells. S cand J. Rheumatol. 1998; 27: 38–41
  • Guise T. A., Yoneda T., Yates A. J., Mundy G. R. The combined effect of tumor-produced parathyroid hormone-related protein and transforming growth factor-alpha enhance hypercalcemia in vivo and bone resorption in vitro. J. Clin. Endocrinol. Metab. 1993; 77: 40–45
  • Suarez-Cuervo C., Harris K. W., Kallman L., Väänänen H. K., Selander K. S. Tumor necrosis factor-alpha induces interleukin-6 production via extracellular-regulated kinase 1 activation in breast cancer cells. Breast Cancer Res. Treat. 2003; 80: 71–78

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