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ORIGINAL ARTICLES Clinical Translational Therapeutics

Cross-Talk Between Notch and EGFR Signaling in Human Breast Cancer Cells

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Pages 533-540 | Published online: 20 Jul 2009

REFERENCES

  • Reedijk M., Pinnaduwage D., Dickson B. C., Mulligan A. M., Zhang H., Bull S. B., O'Malley F. P., Egan S. E., Andrulis I. L. JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. Breast Cancer Res Treat 2007, DOI 10.1007/s10549-007-9805-3
  • Reedijk M., Odorcic S., Chang L., Zhang H., Miller N., McCready D. R., Lockwood G., Egan S. E. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 2005; 65(18)8530–8537
  • Li J. L., Harris A. L. Notch signaling from tumor cells: a new mechanism of angiogenesis. Cancer Cell 2005; 8(1)1–3
  • Clark P. A., Treisman D. M., Ebben J., Kuom J. S. Developmental signaling pathways in brain tumor-derived stem-like cells. Dev Dyn 2007; 236(12)3297–3308
  • Weng A. P., Aster J. C. Multiple niches for Notch in cancer: context is everything. Curr Opin Genet Dev 2004; 14(1)48–54
  • Bhanot U. K., KÖhntop R., Hasel C., MÖller P. Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis. J Pathol 2008; 214(3)312–319
  • Ehebauer M., Hayward P., Arias A. M. Notch, a universal arbiter of cell fate decisions. Science 2006; 314(5804)1414–1415
  • Shi W., Harris A. L. Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials. J Mammary Gland Biol Neoplasia 2006; 11(1)41–52
  • Hurlbut G. D., Kankel M. W., Lake R. J., Artavanis-Tsakonas S. Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol 2007; 19(2)166–175
  • Leong K. G., Karsan A. Recent insights into the role of Notch signaling in tumorigenesis. Blood 2006; 107(6)2223–2233
  • Ramdass B., Maliekal T. T., Lakshmi S., Rehman M., Rema P., Nair P., Mukherjee G., Reddy B. K., Krishna S., Radhakrishna Pillai M. Coexpression of Notch1 and NF-κB signaling pathway components in human cervical cancer progression. Gynecol Oncol 2007; 104(2)352–361
  • Katoh M., Katoh M. Notch signaling in gastrointestinal tract. Int J Oncol 2007; 30(1)247–251
  • Takaori K. Current understanding of precursors to pancreatic cancer. J Hepatobiliary Pancreat Surg 2007; 14(3)217–223
  • Kanamori M., Kawaguchi T., Nigro J. M., Feuerstein B. G., Berger M. S., Miele L., Pieper R. O. Contribution of Notch signaling activation to human glioblastoma multiforme. J Neurosurg 2007; 106(3)417–427
  • Curry C. L., Reed L. L., Broude E., Golde T. E., Miele L., Foreman K. E. Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-κB signaling. Mol Cancer Ther 2007; 6(7)1983–1992
  • Pece S., Serresi M., Santolini E., Capra M., Hulleman E., Galimberti V., Zurrida S., Maisonneuve P., Viale G., Di Fiore P. P. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 2004; 167(2)215–221
  • Lu Z., Jiang G., Blume-Jensen P., Hunter T. Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Mol Cell Biol 2001; 21(12)4016–4031
  • Friedmann B. J., Caplin M., Savic B., Shah T., Lord C. J., Ashworth A., Hartley J. A., Hochhauser D. Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment. Mol Cancer Ther 2006; 5(2)209–218
  • Dutta P. R., Maity A. Cellular responses to EGFR inhibitors and their relevance to cancer therapy. Cancer Lett 2007; 254(2)165–177
  • Qi R., An H., Yu Y., Zhang M., Liu S., Xu H., Guo Z., Cheng T., Cao X. Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res 2003; 63(23)8323–8329
  • Hu Y., Nguyen T. T., Bui K. C., Demello D. E., Smith J. B. A novel inflammation-induced ubiquitin E3 ligase in alveolar type II cells. Biochem Biophys Res Commun 2005; 333(1)253–263
  • Freeman B. B., Daw N. C., Geyer J. R., Furman W. L., Stewart C. F. Evaluation of gefitinib for treatment of refractory solid tumors and central nervous system malignancies in pediatric patients. Cancer Invest 2006; 24(3)310–317
  • Farnie G., Clarke R. B. Mammary stem cells and breast cancer—role of Notch signaling. Stem Cell Rev 2007; 3(2)169–175
  • Bailey J. M., Singh P. K., Hollingsworth M. A. Cancer metastasis facilitated by developmental pathways: sonic hedgehog, Notch, and bone morphogenic proteins. J Cell Biochem 2007; 102(4)829–839
  • Imatani A., Callahan R. Identification of a novel Notch4/int-3 RNA species encoding an activated gene product in certain human tumor cell lines. Oncogene 2000; 19(2)223–231
  • Stylianou S., Clarke R. B., Brennan K. Aberrant activation of Notch signaling in human breast cancer. Cancer Res 2006; 66(3)1517–1525
  • Siziopikou K., Jang M. S., Miao H., Miele L. Notch signaling in ductal carcinoma in situ of the breast [abstract]. Proc Am Assoc Cancer Res 2002; 43: 4
  • Weijzen S., Rizzo P., Braid M., Vaishnav R., Jonkheer S. M., Zlobin A., Osborne B. A., Gottipati S., Aster J. C., Hahn W. C., Rudolf M., Siziopikou K., Kast W. M., Miele L. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med 2002; 8(9)979–986
  • Reedijk M., Odorcic S., Chang L., Zhang H., Miller N., McCready D. R., Lockwood G., Egan S. E. High-level coexpression of Jag1 and Notch1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 2005; 65(18)8530–8537
  • Zang S., Ji Ch., Qu X., Dong X., Ma D., Ye J., Ma R., Dai J., Guo D. A study on Notch signaling in human breast cancer. Neoplasma 2007; 54(4)304–310
  • Dickson B. C., Mulligan A. M., Zhang H., Lockwood G., O'Malley F. P., Egan S. E., Reedijk M. High-level JAG1 mRNA and protein predict poor outcome in breast cancer. Mod Pathol 2007; 20(6)685–693
  • Rizzo P., Miao H., D'Souza G., Osipo C., Yun J., Zhao H., Mascarenhas J., Wyatt D., Antico G., Hao L., Yao K., Rajan P., Hicks C., Siziopikou K., Selvaggi S., Bashir A., Bhandari D., Marchese A., Lendahl U., Qin J. Z., Tonetti D. A., Albain K., Nickoloff B. J., Miele L. Cross-talk between Notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res 2008; 68(13)5226–5235
  • Lee C. W., Raskett C. M., Prudovsky I., Altieri D. C. Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. Cancer Res 2008; 68(13)5273–5281
  • Schiff B. A., McMurphy A. B., Jasser S. A., Younes M. N., Doan D., Yigitbasi O. G., Kim S., Zhou G., Mandal M., Bekele B. N., Holsinger F. C., Sherman S. I., Yeung S. C., El-Naggar A. K., Myers J. N. Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer. Clin Cancer Res 2004; 10(24)8594–8602
  • Doroquez D. B., Rebay I. Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk. Crit Rev Biochem Mol Biol 2006; 41(6)339–385
  • Purow B. W., Sundaresan T. K., Burdick M. J., Kefas B. A., Comeau L. D., Hawkinson M. P., Su Q., Kotliarov Y., Lee J., Zhang W., Fine H. A. Notch-1 regulates transcription of the epidermal growth factor receptor through p53. Carcinogenesis 2008; 29(5)918–925
  • Kolev V., Mandinova A., Guinea-Viniegra J., Hu B., Lefort K., Lambertini C., Neel V., Dummer R., Wagner E. F., Dotto G. P. EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nat Cell Biol 2008; 278(3)1824–1830
  • Farnie G., Clarke R. B., Spence K., Pinnock N., Brennan K., Anderson N. G., Bundred N. J. Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst 2007; 99(8)616–627
  • Wang Z., Zhang Y., Li Y., Banerjee S., Liao J., Sarkar F. H. Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells. Mol Cancer Ther 2006; 5(3)483–493

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