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Cancer Investigation Volume 37, 2019 - Issue 2
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Original Articles

Aquaporin-4 Expression Patterns in Glioblastoma Pre-Chemoradiation and at Time of Suspected Progression

Michael LevyDepartment of Neurology, Johns Hopkins University, Baltimore, MD, USA; ;Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; ORCID Iconhttps://orcid.org/0000-0002-7969-8346View further author information
ORCID Icon,
Scott BarlettaDepartment of Neurology, Johns Hopkins University, Baltimore, MD, USA; View further author information
,
Hwa HuangDepartment of Neurology, Johns Hopkins University, Baltimore, MD, USA; View further author information
,
Stuart A. GrossmanDepartment of Oncology, Johns Hopkins University, Baltimore, MD, USA; View further author information
,
Fausto J. RodriguezDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA; View further author information
,
Susannah G. EllsworthDepartment of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, USA; ORCID Iconhttp://orcid.org/0000-0001-8546-3642View further author information
ORCID Icon,
Omar DzayeDepartment of Oncology, Johns Hopkins University, Baltimore, MD, USA; ;Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; ;Department of Radiology and Neuroradiology, Charité, Berlin, GermanyView further author information
&
Matthias HoldhoffDepartment of Oncology, Johns Hopkins University, Baltimore, MD, USA; Correspondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3285-3484View further author information
ORCID Icon show all
Pages 67-72 | Received 13 May 2018, Accepted 29 Dec 2018, Published online: 15 Mar 2019

References

  • Ostrom QT, Gittleman H, Liao P, Vecchione-Koval T, Wolinsky Y, Kruchko C, et al. CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in tdhe United States in 2010-2014. Neuro Oncol. 2017;19(suppl_5):v1–v88. doi:10.1093/neuonc/nox158.
  • Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJB, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987–996. doi:10.1056/NEJMoa043330.
  • Lin ZX. Glioma-related edema: new insight into molecular mechanisms and their clinical implications. Chin J Cancer. 2013;32(1):49–52. doi:10.5732/cjc.012.10242.
  • Ambady P, Bettegowda C, Holdhoff M. Emerging methods for disease monitoring in malignant gliomas. CNS Oncol. 2013;2(6):511–522. doi:10.2217/cns.13.44.
  • Mou K, Chen M, Mao Q, Wang P, Ni R, Xia X, et al. AQP-4 in peritumoral edematous tissue is correlated with the degree of glioma and with expression of VEGF and HIF-alpha. J Neurooncol. 2010;100(3):375–383. doi:10.1007/s11060-010-0205-x.
  • Borgnia M, Nielsen S, Engel A, Agre P. Cellular and molecular biology of the aquaporin water channels. Annu Rev Biochem. 1999;68:425–458. doi:10.1146/annurev.biochem.68.1.425.
  • Saadoun S, Papadopoulos MC, Davies DC, Krishna S, Bell BA. Aquaporin-4 expression is increased in oedematous human brain tumours. J Neurol Neurosurg Psychiatry. 2002;72(2):262–265.
  • Warth A, Simon P, Capper D, Goeppert B, Tabatabai G, Herzog H, et al. Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival. J Neurosci Res. 2007;85(6):1336–1346. doi:10.1002/jnr.21224.
  • Wang P, Ni RY, Chen MN, Mou KJ, Mao Q, Liu YH. Expression of aquaporin-4 in human supratentorial meningiomas with peritumoral brain edema and correlation of VEGF with edema formation. Genet Mol Res. 2011;10(3):2165–2171. doi:10.4238/vol10-3gmr1212.

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