References
- Choudhury D, Tseng TW, Swartz E. The business of cultured meat. Trends Biotechnol. 2020;38(6):573–577.
- Stephens N, Di Silvio L, Dunsford I, et al. Bringing cultured meat to market: technical, socio-political, and regulatory challenges in cellular agriculture. Trend Food Sci Technol. 2018;78:155–166.
- Bonny SPF, Gardner GE, Pethick DW, et al. What is artificial meat and what does it mean for the future of the meat industry. J Integr Agric. 2015;14(2):255–263.
- Swartz E. Meeting the needs of the cell-based meat industry. Chem Eng Prog. 2019;115(10):41–45.
- Mekonnen MM, Hoekstra AY. A global assessment of the water footprint of farm animal products. Ecosystems. 2012;15(3):401–415.
- Greger M. The human/animal interface: emergence and resurgence of zoonotic infectious diseases. Crit Rev Microbiol. 2007;33(4):243–299.
- Ben-Arye T, Levenberg S. Tissue engineering for clean meat production. Front Sustain Food Syst. 2019;3(46):1–19.
- Ong S, Choudhury D, Naing MW. Cell-based meat: current ambiguities with nomenclature. Trends Food Sci Technol. 2020;102:223–231.
- Ostrovidov S, et al. Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications. Tissue Eng Part B Rev. 2014;20(5):403–436.
- Gaydhane MK, Mahanta U, Sharma CS, et al. Cultured meat: state of the art and future. Biomanuf Rev. 2018;3(1):1.
- Datar I, Betti M. Possibilities for an in vitro meat production system. Innovative Food Sci Emerg Technol. 2010;11(1):13–22.
- Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126(4):663–676.
- Amit M, et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol. 2000;227(2):271–278.
- Cassiday L. Clean meat. Inform. 2018;29(2):6–14.
- Asakura A, Rudnicki MA, Komaki M. Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation. Differentiation. 2001;68(4):245–253.
- O'Brien FJ. Biomaterials & scaffolds for tissue engineering. Mater Today. 2011;14(3):88–95.
- Specht EA, Welch DR, Rees Clayton EM, et al. Opportunities for applying biomedical production and manufacturing methods to the development of the clean meat industry. Biochem Eng J. 2018;132:161–168.
- King T. Meat re-imagined: the global emergence of alternative proteins – what does it mean for Australia? Food Front. 2019;71(3):24.
- K. Handral H, et al. 3D printing of cultured meat products. Crit Rev Food Sci Nutr. 2020:1–10.
- Edelman P, et al. Commentary: in vitro-cultured meat production. Tissue Eng. 2005;11(5–6):659–662.
- Van Eelen W, van Kooten W, Westerhof W. Industrial production of meat from in vitro cell cultures; 1999. WO/1999/031223: Patent Description http://www.wipo.int/pctdb/en/wo.jsp.
- Lovett M, et al. Vascularization strategies for tissue engineering. Tissue Eng Part B Rev. 2009;15(3):353–370.
- Papenburg BJ, et al. Development and analysis of multi-layer scaffolds for tissue engineering. Biomaterials. 2009;30(31):6228–6239.
- Li H, et al. Human mesenchymal stem-cell behaviour on direct laser micropatterned electrospun scaffolds with hierarchical structures. Macromol Biosci. 2013;13(3):299–310.
- Mohanty S, et al. Fabrication of scalable and structured tissue engineering scaffolds using water dissolvable sacrificial 3D printed moulds. Mater Sci Eng C. 2015;55:569–578.
- Borenstein JT, Terai H, King KR, et al. Microfabrication technology for vascularized tissue engineering. Biomed Microdevices. 2002;4(3):167–175.
- MacQueen LA, et al. Muscle tissue engineering in fibrous gelatin: implications for meat analogs. NPJ Sci Food. 2019;3(1).
- Modulevsky DJ, Cuerrier CM, Pelling AE. Biocompatibility of subcutaneously implanted plant-derived cellulose biomaterials. PloS One. 2016;11(6):e0157894.
- Acevedo CA, Orellana N, Avarias K, et al. Micropatterning technology to design an edible film for in vitro meat production. Food Bioprocess Technol. 2018;11(7):1267–1273.
- Verbruggen S, et al. Bovine myoblast cell production in a microcarriers-based system. Cytotechnology. 2018;70(2):503–512.
- Ben-Arye T, Shandalov Y, Ben-Shaul S, et al. Textured soy protein scaffolds enable the generation of three-dimensional bovine skeletal muscle tissue for cell-based meat. Nat Food. 2020;1(4):210–220.
- Enrione J, Blaker J, Brown D, et al. Edible scaffolds based on non-mammalian biopolymers for myoblast growth. Materials. 2017;10(12):1404.
- Bodiou V, Moutsatsou P, Post MJ. Microcarriers for upscaling cultured meat production. Front Nutr. 2020;7:10.
- Hanga MP, Ali J, Moutsatsou P, et al. Bioprocess development for scalable production of cultivated meat. Biotechnol Bioeng. 2020;117(10):3029–3039.,
- Bhaskar B, et al. Design and assessment of a dynamic perfusion bioreactor for large bone tissue engineering scaffolds. Appl Biochem Biotechnol. 2018;185(2):555–563.
- Gomes ME, Bossano CM, Johnston CM, et al. In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor. Tissue Eng. 2006;12(1):177–188.
- Williams C, Wick TM. Perfusion bioreactor for small diameter tissue-engineered arteries. Tissue Eng. 2004;10(5–6):930–941.
- Allan SJ, De Bank PA, Ellis MJ. Bioprocess design considerations for cultured meat production with a focus on the expansion bioreactor. Front Sustain Food Syst. 2019;3(44):1–9.
- Zhang G, Zhao X, Li X, et al. Challenges and possibilities for bio-manufacturing cultured meat. Trends Food Sci Technol. 2020;97:443–450.
- Li X, Zhang G, Zhao X, et al. A conceptual air-lift reactor design for large scale animal cell cultivation in the context of in vitro meat production. Chem Eng Sci. 2020;211:115269.
- Orellana N, Sánchez E, Benavente D, et al. A new edible film to produce in vitro meat. Foods. 2020;9(2):185.
- Eelen WV. Industrial scale production of meat from in vitro cell cultures; 1999. https://patents.google.com/patent/WO1999031222A1/en
- Stevens B, et al. A review of materials, fabrication methods, and strategies used to enhance bone regeneration in engineered bone tissues. J Biomed Mater Res B Appl Biomater. 2008;85(2):573–582.
- Huang J, et al. Evaluation of tofu as a potential tissue engineering scaffold. J Mater Chem B. 2018;6(9):1328–1334.
- Reddy N, Yang Y. Potential of plant proteins for medical applications. Trends Biotechnol. 2011;29(10):490–498.
- Powell CA, et al. Mechanical stimulation improves tissue-engineered human skeletal muscle. Am J Physiol Cell Physiol. 2002;283(5):C1557–C1565.
- Hinds S, et al. The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle. Biomaterials. 2011;32(14):3575–3583.
- Smith A, et al. Characterization and optimization of a simple, repeatable system for the long term in vitro culture of aligned myotubes in 3D. J Cell Biochem. 2012;113(3):1044–1053.
- Vandenburgh H, et al. Drug‐screening platform based on the contractility of tissue‐engineered muscle. Muscle Nerve. 2008;37(4):438–447.
- Snyman C, Goetsch KP, Myburgh KH, et al. Simple silicone chamber system for 3D skeletal muscle tissue formation. Front Physiol. 2013;4:349.
- Post MJ. Cultured meat from stem cells: challenges and prospects. Meat Sci. 2012;92(3):297–301.
- Post MJ. Cultured beef: medical technology to produce food. J Sci Food Agric. 2014;94(6):1039–1041.
- Bian W, Bursac N. Engineered skeletal muscle tissue networks with controllable architecture. Biomaterials. 2009;30(7):1401–1412.
- Gholobova D, et al. Endothelial network formation within human tissue-engineered skeletal muscle. Tissue Eng Part A. 2015;21(19–20):2548–2558.
- Ahmed TA, Dare EV, Hincke M. Fibrin: a versatile scaffold for tissue engineering applications. Tissue Eng Part Rev. 2008;14(2):199–215.
- Noori A, Ashrafi SJ, Vaez-Ghaemi R, et al. A review of fibrin and fibrin composites for bone tissue engineering. IJN. 2017;12:4937–4961.
- Spicer CD. Hydrogel scaffolds for tissue engineering: the importance of polymer choice. Polym Chem. 2020;11(2):184–219.
- Colwell AS, Longaker MT, Lorenz HP. Fetal wound healing. Front Biosci. 2003;8(6):S1240–S1248.
- Halbleib M, et al. Tissue engineering of white adipose tissue using hyaluronic acid-based scaffolds. I: in vitro differentiation of human adipocyte precursor cells on scaffolds. Biomaterials. 2003;24(18):3125–3132.
- Allison DD, Grande-Allen KJ. Hyaluronan: a powerful tissue engineering tool. Tissue Eng. 2006;12(8):2131–2140.
- Davidenko N, et al. Collagen–hyaluronic acid scaffolds for adipose tissue engineering. Acta Biomater. 2010;6(10):3957–3968.
- Sze JH, Brownlie JC, Love CA. Biotechnological production of hyaluronic acid: a mini review. 3 Biotech. 2016;6(1):67.
- Qazi TH, et al. Biomaterials based strategies for skeletal muscle tissue engineering: existing technologies and future trends. Biomaterials. 2015;53:502–521.
- Zakhem E, et al. Chitosan-based scaffolds for the support of smooth muscle constructs in intestinal tissue engineering. Biomaterials. 2012;33(19):4810–4817.
- Ospina NM, et al. Isolation of chitosan from Ganoderma lucidum mushroom for biomedical applications. J Mater Sci – Mater Med. 2015;26(3):135.
- Jana S, Cooper A, Zhang M. Chitosan scaffolds with unidirectional microtubular pores for large skeletal myotube generation. Adv Healthcare Mater. 2013;2(4):557–561.
- Campuzano S, Pelling AE. Scaffolds for 3D cell culture and cellular agriculture applications derived from non-animal sources. Front Sustain Food Syst. 2019;3:38.
- Taylor K, Alvarez LR. An estimate of the number of animals used for scientific purposes worldwide in 2015. Altern Lab Anim. 2019;47(5–6):196–213.
- Gershlak JR, et al. Crossing kingdoms: using decellularized plants as perfusable tissue engineering scaffolds. Biomaterials. 2017;125:13–22.
- Jahangirian H, et al. Status of plant protein-based green scaffolds for regenerative medicine applications. Biomolecules. 2019;9(10):619. https://www.mdpi.com/2218-273X/9/10/619
- Caliari SR, Burdick JA. A practical guide to hydrogels for cell culture. Nat Methods. 2016;13(5):405–414.
- Percival NJ. Classification of wounds and their management. Surgery. 2002;20(5):114–117.
- Liu X, et al. Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials. 2005;26(1):109–115.
- Wang H-J, Lin Z-X, Liu X-M, et al. Heparin-loaded zein microsphere film and hemocompatibility. J Controlled Release. 2005;105(1–2):120–131.
- Jiang Q, et al. Water-stable electrospun collagen fibers from a non-toxic solvent and crosslinking system. J Biomed Mater Res A. 2013;101(5):1237–1247.
- Qu Z-H, et al. Evaluation of the zein/inorganics composite on biocompatibility and osteoblastic differentiation. Acta Biomater. 2008;4(5):1360–1368.
- Iravani S, Varma RS. Plants and plant-based polymers as scaffolds for tissue engineering. Green Chem. 2019;21(18):4839–4867.
- Silva SS, Oliveira JM, Mano JF, et al. Physicochemical characterization of novel chitosan-soy protein/TEOS porous hybrids for tissue engineering applications. MSF. 2006;514-516:1000–1004.
- Luo L-H, et al. Preparation, characterization, and in vitro and in vivo evaluation of cellulose/soy protein isolate composite sponges. J Biomater Appl. 2010;24(6):503–526.
- Luo L, et al. Construction of nerve guide conduits from cellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect. Biochem Biophys Res Commun. 2015;457(4):507–513.
- Chien KB, Shah RN. Novel soy protein scaffolds for tissue regeneration: material characterization and interaction with human mesenchymal stem cells. Acta Biomater. 2012;8(2):694–703.
- Tchobanian A, Van Oosterwyck H, Fardim P. Polysaccharides for tissue engineering: current landscape and future prospects. Carbohydr Polym. 2019;205:601–625.
- Trache D, et al. Recent progress in cellulose nanocrystals: sources and production. Nanoscale. 2017;9(5):1763–1786.
- Rodríguez K, Renneckar S, Gatenholm P. Biomimetic calcium phosphate crystal mineralization on electrospun cellulose-based scaffolds. ACS Appl Mater Interfaces. 2011;3(3):681–689.
- Courtenay JC, et al. Surface modified cellulose scaffolds for tissue engineering. Cellulose. 2017;24(1):253–267.
- Ninan N, et al. Pectin/carboxymethyl cellulose/microfibrillated cellulose composite scaffolds for tissue engineering. Carbohydr Polym. 2013;98(1):877–885.
- Bhat ZF, Fayaz H. Prospectus of cultured meat – advancing meat alternatives. J Food Sci Technol. 2011;48(2):125–140.
- Kadim IT, Mahgoub O, Baqir S, et al. Cultured meat from muscle stem cells: a review of challenges and prospects. J Integr Agric. 2015;14(2):222–233.
- Langelaan MLP, Boonen KJM, Polak RB, et al. Meet the new meat: tissue engineered skeletal muscle. Trends Food Sci Technol. 2010;21(2):59–66.
- Ma PX. Scaffolds for tissue fabrication. Mater Today. 2004;7(5):30–40.
- Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials. 1996;17(2):93–102.
- Mooney DJ, Sano K, Kaufmann PM, et al. Long-term engraftment of hepatocytes transplanted on biodegradable polymer sponges. J Biomed Mater Res. 1997;37(3):413–420.
- Toong DWY, Toh HW, Ng JCK, et al. Bioresorbable polymeric scaffold in cardiovascular applications. IJMS. 2020;21(10):3444.
- An J, et al. Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs. Nanomedicine (Lond). 2013;8(4):591–602.
- Wong HK, et al. Novel method to improve vascularization of tissue engineered constructs with biodegradable fibers. Biofabrication. 2016;8(1):015004.
- Khadka A, et al. Polylactic Acid (PLA): an alternative edible packaging material from dairy byproducts; 2016.
- Carletti E, Motta A, Migliaresi C. Scaffolds for tissue engineering and 3D cell culture. Methods Mol Biol. 2011;695:17–39.
- Lv Q, Feng Q. Preparation of 3-D regenerated fibroin scaffolds with freeze drying method and freeze drying/foaming technique. J Mater Sci Mater Med. 2006;17(12):1349–1356.
- Zhang H, et al. Aligned two- and three-dimensional structures by directional freezing of polymers and nanoparticles. Nat Mater. 2005;4(10):787–793.
- Li D, Xia Y. Electrospinning of nanofibers: reinventing the wheel? Adv Mater. 2004;16(14):1151–1170.
- Brown JH, et al. Nanofibrous PLGA electrospun scaffolds modified with type I collagen influence hepatocyte function and support viability in vitro. Acta Biomater. 2018;73:217–227.
- Chen H, Peng Y, Wu S, et al. Electrospun 3D fibrous scaffolds for chronic wound repair. Materials. 2016;9(4):272.
- Das P, DiVito MD, Wertheim JA, et al. Collagen-I and fibronectin modified three-dimensional electrospun PLGA scaffolds for long-term in vitro maintenance of functional hepatocytes. Mater Sci Eng C. 2020;111:110723.
- Chen H, Lui YS, Tan ZW, et al. Migration and phenotype control of human dermal fibroblasts by electrospun fibrous substrates. Adv Healthcare Mater. 2019;8(9):1801378.
- Kolesky DB, et al. Three-dimensional bioprinting of thick vascularized tissues. Proc Natl Acad Sci USA. 2016;113(12):3179–3184.
- Tallawi M, et al. Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review. J R Soc Interface. 2015;12(108):20150254–20150254.
- Lerman MJ, et al. The evolution of polystyrene as a cell culture material. Tissue Eng Part B Rev. 2018;24(5):359–372.
- Post MJ, Levenberg S, Kaplan DL, et al. Scientific, sustainability and regulatory challenges of cultured meat. Nat Food. 2020;1(7):403–415.
- Mizukami A, Swiech K. Mesenchymal stromal cells: from discovery to manufacturing and commercialization. Stem Cells Int. 2018;2018:1–13.
- Benjaminson MA, Gilchriest JA, Lorenz M. In vitro edible muscle protein production system (MPPS): stage 1, fish. Acta Astronaut. 2002;51(12):879–889.
- Bhat ZF, Kumar S, Bhat HF. In vitro meat: a future animal-free harvest. Crit Rev Food Sci Nutr. 2017;57(4):782–789.
- Agency SF. Guidance information on safety assessment of novel foods. F.R.M. Division, Editor. Singapore: Singapore Food Agency; 2019.
- Festing S, Wilkinson R. The ethics of animal research. Talking point on the use of animals in scientific research. EMBO Rep. 2007;8(6):526–530.
- Ismail I, Hwang Y-H, Joo S-T. Meat analog as future food: a review. J Anim Sci Technol. 2020;62(2):111–120.
- Choudhury D, et al. Commercialization of plant-based meat alternatives. Trends Plant Sci. 25(11):1–4.