Diazepam affects both level and amplitude of rat locomotor activity rhythm but has no effect on core body temperature

References

• Atsmon J., Oaknin S., Laudon M., Laschiner S., Gavish M., Dagan Y., Zisapel N. Reciprocal effects of chronic diazepam and melatonin on brain melatonin and benzodiazepine binding sites. J. Pineal Res. 1996; 20: 65–71
   PubMed Web of Science ®Google Scholar
• Benstaali C., Bogdan A., Touitou Y. Effect of a short photoperiod on circadian rhythms of body temperature and motor activity in old rats. Pflügers Arch. Eur. J. Physiol. 2002; 444: 73–79
   PubMed Web of Science ®Google Scholar
• Childs G., Redfern P. H. A circadian rhythm in passive avoidance behaviour: the effect of phase shift and the benzodiazepines. Neuropharmacology 1981; 20: 1365–1366
   PubMed Web of Science ®Google Scholar
• Clark S. M., Lipton J. M. Effects of diazepam on body temperature of the aged squirrel monkey. Brain Res. Bull. 1981; 7: 5–9
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Touitou Y. Chronic diazepam administration differentially affects melatonin synthesis in rat pineal and Harderian glands. Psychopharmacology 2001; 154: 403–407
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Touitou Y. Effects of diazepam and its metabolites on nocturnal melatonin secretion in the rat pineal and Harderian glands. A comparative in vivo and in vitro study. Chronobiol. Int. 2003a; 20: 285–297
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Touitou Y. Effets du diazépam et de ses métabolites sur la sécrétion nocturne de la mélatonine par la glande pinéale et la glande de Harder chez le rat: Etude in vivo. Mécanismes et Physiopathologie des Fonctions Rythmiques, Y. Touitou. Vernazobres‐Grego Publications, Paris 2003b; 139–148
   Google Scholar
• File S. E. The history of benzodiazepine dependence: A review of animal studies. Neurosci. Biobehav. Rev. 1990; 14: 135–146
   PubMed Web of Science ®Google Scholar
• Houpt T., Boulos Z., Moore‐Ede M. C. Circadian phase response curve to diazepam for hamsters in constant light. Soc. Neurosci. Abstr. 1986; 12: 1071
   Google Scholar
• Inouye S. T., Kawamura H. Characteristics of a circadian pacemaker in the suprachiasmatic nucleus. J. Comp. Physiol. 1982; 146: 153–160
   Web of Science ®Google Scholar
• Mailliet F., Galloux P., Poisson D. Comparative effects of melatonin, zolpidem and diazepam on sleep, body temperature, blood pressure and heart rate measured by radiotelemetry in Wistar rats. Psychopharmacology 2001; 156: 417–426
   PubMed Web of Science ®Google Scholar
• Martin S. M., Malkinson T. J., Veale W. L. Diazepam effects on temperature regulation in the rabbit. Proceed. Canad. Fed. Biol. Soc. Abstr. 1983; 32: 168
   Google Scholar
• Mrosovsky N., Salmon P. A. Triazolam and phase‐shifting acceleration re‐evaluated. Chronobiol. Int. 1990; 7: 35–41
   PubMed Web of Science ®Google Scholar
• Perreau‐Lenz S., Pévet P., Buijs R. M., Kalsbeek A. The biological clock: the bodyguard of temporal homeostasis. Chronobiol. Int. 2004; 21: 1–26
   PubMed Web of Science ®Google Scholar
• Pitrosky B., Kirsch R., Malan A., Mocaer E., Pévet P. Organisation of rat circadian rhythms during daily infusion of melatonin or S20098, a melatonin agonist. Am. J. Physiol. 1999; 277: R812–R828
   PubMed Web of Science ®Google Scholar
• Pittendrigh C. S., Daan S. A functional analysis of circadian pacemakers in nocturnal rodents The stability and lability of spontaneous frequency. J. Comp. Physiol. 1976; 106: 223–252
   Web of Science ®Google Scholar
• Ralph M. R., Menaker M. Effects of diazepam on circadian phase advances and delays. Brain Res. 1986; 372: 405–408
   PubMed Web of Science ®Google Scholar
• Rickles K., De Martinis N., Aufdembrinke B. A double‐blind, placebo‐controlled trial of abecarnil and diazepam in the treatment of patients with generalized anxiety disorder. J. Clin. Psychopharmacol. 2000; 20: 12–18
   PubMed Web of Science ®Google Scholar
• Sipos M. L., Burchnell V., Galbicka G. Dose‐response curves and time‐course effects of selected anticholinergics on locomotor activity in rats. Psychopharmacology 1999; 147: 250–256
   PubMed Web of Science ®Google Scholar
• Subramanian P., Subbaraj R. Diazepam phase shifts the circadian clock of the field mouse. Mus booduga. J. Biosci. 1993; 18: 103–110
   Web of Science ®Google Scholar
• Subramanian P., Subbaraj R. Diazepam modulates the period of locomotor rhythm in mice (Mus booduga) and attenuates light‐induced phase advances. Pharmacol. Biochem. Behav. 1996; 54: 393–398
   PubMed Web of Science ®Google Scholar
• Touitou Y., Portaluppi F., Smolensky M. H., Rensing L. Ethical principles and standards for the conduct of human and animal biological rhythm research. Chronobiol. Int. 2004; 21: 161–170
   PubMed Web of Science ®Google Scholar
• Turek F. W., Losee‐Olsen S. Dose response curve for the phase shifting effect of triazolam on the mammalian circadian clock. Life Sci. 1987; 40: 1033–1038
   PubMed Web of Science ®Google Scholar
• Van Reeth O., Turek F. W. Changes in the phase response curve of the circadian clock to a phase‐shifting stimulus. J. Biol. Rhythms 1992; 7: 137–147
   PubMed Web of Science ®Google Scholar
• Wakabayashi H., Shimada K., Satoh T. Effects of adrenergic blockers or bicuculline on diazepam induced changes in rat pineal melatonin synthesis in vivo and in vitro. Chem. Pharm. Bull. 1991a; 39: 2677–2680
   PubMed Web of Science ®Google Scholar
• Wakabayashi H., Shimada K., Satoh T. Effects of diazepam administration on melatonin synthesis in the rat pineal gland in vivo. Chem. Pharm. Bull. 1991b; 39: 2674–2676
   PubMed Web of Science ®Google Scholar
• Witte K., Engelhardt S., Janssen B. J., Lohse M., Lemmer B. Circadian and short‐term regulation of blood pressure and heart rate in transgenic mice with cardiac overexpression of the beta1‐adrenoreceptor. Chronobiol. Int. 2004; 21: 205–216
   PubMed Web of Science ®Google Scholar
• Yokota S. I., Horikawa K., Akiyama M., Moriya T., Ebihara S., Komuro G., Ohta T., Shibata S. Inhibitory action of brotizolam on circadian and light‐induced per1 and per2 expression in the hamster suprachiasmatic nucleus. Br. J. Pharmacol. 2000; 131: 1739–1747
   PubMed Web of Science ®Google Scholar
• Zuther P., Lemmer B. WIN‐ABPM‐FIT–a comprehensive, rapid and easy‐to‐use program to analyze 24‐h blood pressure data from humans and telemetric data from animals. Naunyn‐Schmiedeberg's Arch. Pharmacol. 2003; 367(suppl 1)A484
   Google Scholar