Advanced search
Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 25, 2008 - Issue 5
Submit an article Journal homepage
617
Views
87
CrossRef citations to date
0
Altmetric
SHORT COMMUNICATIONS

Diurnal Variation of Plasma Brain‐Derived Neurotrophic Factor (BDNF) in Humans: An Analysis of Sex Differences

Armando Piccinni Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
,
MD Donatella Marazziti Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, ItalyCorrespondence[email protected]
,
Alessandro Del Debbio Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
,
Carolina Bianchi Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
,
Isabella Roncaglia Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
,
Claudio Mannari Dipartimento di Neuroscienze, University of Pisa, Pisa, Italy
,
Nicola Origlia Institute of Neuroscience, National Research Council, Pisa, Italy
,
Mario Catena Dell'Osso Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
,
Gabriele Massimetti Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
,
Luciano Domenici Institute of Neuroscience, National Research Council, Pisa, Italy; Dipartimento di Scienze e Tecnologie Biomediche, University of L'Aquila, L'Aquila, Italy
&
Liliana Dell'Osso Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Pisa, Italy
 show all
Pages 819-826 | Received 21 Jan 2008, Accepted 15 May 2008, Published online: 07 Jul 2009

References

  • Begliuomini S, Casarosa E, Pluchino N, Lenzi E, Centofanti M, Freschi L, Pieri M, Genazzani A D, Luisi S, Genazzani A R. Influence of endogenous and exogenous sex hormones on plasma brain‐derived neurotrophic factor. Hum. Reprod. 2007; 22: 995–1002
  • Begliuomini S, Lenzi E, Ninni F, Casarosa E, Merlini S, Pluchino N, Valentino V, Luisi S, Luisi M, Genazzani A R. Plasma brain‐derived neurotrophic factor daily variations in men: Correlations with cortisol circadian rhythm. J. Endocrinol. 2008; 197: 429–435
  • Bersani G, Iannitelli A, Massoni E, Garavini A, Grilli A, Di Giannantonio M, Conti C M, Pancheri P. Ultradian variation of nerve growth factor plasma levels in healthy and schizophrenic subjects. Int. J. Immunopathol. Pharmacol. 2004; 17: 367–372
  • Dolci C, Montaruli A, Roveda E, Barajon I, Vizzotto L, Grassi Zucconi G, Carandente F. Circadian variations in expression of the trkB receptor in adult rat hippocampus. Brain Res. 2003; 994: 67–72
  • Duman R S, Monteggia L M. A neurotrophic model for stress‐related mood disorders. Biol. Psychiatry 2006; 59: 1116–1127
  • Ebisawa T. Circadian rhythms in the CNS and peripheral clock disorders: Human sleep disorders and clock genes. J. Pharmacol. Sci. 2007; 103: 150–154
  • Franklin T B, Perrot‐Sinal T S. Sex and ovarian steroids modulate brain‐derived neurotrophic factor (BDNF) protein levels in rat hippocampus under stressful and non‐stressful conditions. Psychoneuroendocrinology 2006; 31: 38–48
  • Gibbs R B. Treatment with estrogen and progesterone affects relative levels of brain‐derived neurotrophic factor mRNA and protein in different regions of the adult rat brain. Brain Res. 1999; 884: 20–27
  • Karege F, Schwald M, Cisse M. Postnatal developmental profile of brain‐derived neurotrophic factor in rat brain and platelets. Neurosci. Lett. 2002; 328: 261–264
  • Karege F, Bondolfi G, Gervasoni N, Schwald M, Aubry JM, Bertschy G. Low brain−derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol. Psychiatry 2005; 57: 1068–1072
  • Levi F, Schibler U. Circadian rhythms: mechanisms and therapeutic implications. Annu. Rev. Pharmacol. Toxicol. 2007; 47: 593–628
  • Liang F Q, Sohrabji F, Miranda R, Earnest B, Earnest D. Circadian rhythm of brain‐derived neurotrophic factor in the rat suprachiasmatic nucleus. Neurosci. Lett. 1998; 242: 89–92
  • Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C, Schuff‐Werner P, Virchow J C. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol. Aging 2005; 26: 115–123
  • Palomino A, Vallejo‐Illarramendi A, González‐Pinto A, Aldama A, González‐Gómez C, Mosquera F, González‐García G, Matute C. Decreased levels of plasma BDNF in first‐episode schizophrenia and bipolar disorder patients. Schizophr. Res. 2006; 86: 321–322
  • Piccinni A, Marazziti D, Catena M, Domenici L, Del Debbio A, Bianchi C, Mannari C, Martini C, Da Pozzo E, Schiavi E, Mariotti A, Roncaglia I, Palla A, Consoli G, Giovannini L, Massimetti G, Dell'Osso L. Plasma and serum brain‐derived neurotropic factor (BDNF) in depressed patients during one year of antidepressant treatments. J. Affect Disord. 2008; 105: 279–283
  • Pirildar S, Gönül A S, Taneli F, Akdeniz F. Low serum levels of brain‐derived neurotrophic factor in patients with schizophrenia do not elevate after antipsychotic treatment. Prog. Neuropsychopharmacol. Biol. Psychiatry 2004; 28: 709–713
  • Poo M M. Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2001; 2: 24–32
  • Schaaf M J, Duurland R, De Kloet E R, Vreugdenhil E. Circadian variation in BDNF mRNA expression in the rat hippocampus. Brain Res. Mol. Brain Res. 2000; 75: 342–344
  • Segal M, Murphy D. Estradiol induces formation of dendritic spines in hippocampal neurons: Functional correlates. Horm. Behav. 2001; 40: 156–159
  • Touitou Y, Smolensky M H, Portaluppi F. Ethics, standards, and procedures of animal and human chronobiology research. Chronobiol. Int. 2006; 23: 1083–1096
  • Trajkovska V, Marcussen A B, Vinberg M, Hartvig P, Aznar S, Knudsen G M. Measurements of brain‐derived neurotrophic factor: Methodological aspects and demographical data. Brain Res. Bull. 2007; 73: 143–149
  • Wehr T A. Photoperiodism in humans and other primates: Evidence and implications. J. Biol. Rhythms 2001; 16: 348–364
  • Weitzman E D, Fukushima C, Nogeire C. Twenty‐four hour pattern of the episodic secretion of cortisol in normal subjects. J. Clin. Endocrinol. Metab. 1971; 19(33)14–22

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.