Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 35, 2018 - Issue 2
385
Views
22
CrossRef citations to date
0
Altmetric
Original Articles

Repercussions of hypo and hyperthyroidism on the heart circadian clock

, , &
Pages 147-159 | Received 28 Jul 2017, Accepted 02 Oct 2017, Published online: 07 Nov 2017

References

  • Ahlersova E, Ahlers I, Kassayova M, Smajda B. 1997. Circadian oscillations of serum thyroid hormones in the laboratory rat: The effect of photoperiods. Physiol Res. 46:443–49.
  • Bargi-Souza P, Romano RM, Salgado Rde M, Goulart-Silva F, Brunetto EL, Zorn TM, Nunes MT. 2013. Triiodothyronine rapidly alters the TSH content and the secretory granules distribution in male rat thyrotrophs by a cytoskeleton rearrangement-independent mechanism. Endocrinology. 154:4908–18. doi:10.1210/en.2013-1508.
  • Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, De Ferranti SD, Floyd J, Fornage M, Gillespie C, et al. 2017. Heart disease and stroke statistics-2017 update: a report from the American Heart Association. Circulation. 135:e146–e603. doi:10.1161/CIR.0000000000000485.
  • Biondi B, Klein I. 2004. Hypothyroidism as a risk factor for cardiovascular disease. Endocrine. 24:1–13. doi:10.1385/ENDO:24:1:001.
  • Biondi B, Palmieri EA, Lombardi G, Fazio S. 2002. Effects of thyroid hormone on cardiac function: The relative importance of heart rate, loading conditions, and myocardial contractility in the regulation of cardiac performance in human hyperthyroidism. J Clin Endocrinol Metab. 87:968–74. doi:10.1210/jcem.87.3.8302.
  • Bray MS, Shaw CA, Moore MW, Garcia RA, Zanquetta MM, Durgan DJ, Jeong WJ, Tsai JY, Bugger H, Zhang D, et al. 2008. Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression. Am J Physiol Heart Circ Physiol. 294:H1036–1047. doi:10.1152/ajpheart.01291.2007.
  • Campos-Barros A, Musa A, Flechner A, Hessenius C, Gaio U, Meinhold H, Baumgartner A. 1997. Evidence for circadian variations of thyroid hormone concentrations and type II 5ʹ-iodothyronine deiodinase activity in the rat central nervous system. J Neurochem. 68:795–803. doi:10.1046/j.1471-4159.1997.68020795.x.
  • Cerbone M, Capalbo D, Wasniewska M, Mattace Raso G, Alfano S, Meli R, De Luca F, Salerno M. 2014. Cardiovascular risk factors in children with long-standing untreated idiopathic subclinical hypothyroidism. J Clin Endocrinol Metab. 99:2697–703. doi:10.1210/jc.2014-1761.
  • Chu G, Misawa I, Chen H, Yamauchi N, Shigeyoshi Y, Hashimoto S, Hattori MA. 2012. Contribution of FSH and triiodothyronine to the development of circadian clocks during granulosa cell maturation. Am J Physiol Endocrinol Meta. 302:E645–653. doi:10.1152/ajpendo.00470.2011.
  • Cornelissen G, Halberg F, Stebbings J, Halberg E, Carandente F, Hsi B. 1980. Chronobiometry with pocket calculators and computer systems. Ric Clin Lab. 10:333–85.
  • Danzi S, Klein I. 2012. Thyroid hormone and the cardiovascular system. Med Clin North Am. 96:257–68. doi:10.1016/j.mcna.2012.01.006.
  • Dillmann WH. 1996. Editorial: Thyroid hormone action and cardiac contractility - a complex affair. Endocrinology. 137:799–801. doi:10.1210/endo.137.3.8603587.
  • Dillmann WH. 2002. Cellular action of thyroid hormone on the heart. Thyroid: J Am Thyroid Assoc. 12:447–52. doi:10.1089/105072502760143809.
  • Durgan DJ, Tsai JY, Grenett MH, Pat BM, Ratcliffe WF, Villegas-Montoya C, Garvey ME, Nagendran J, Dyck JR, Bray MS, et al. 2011. Evidence suggesting that the cardiomyocyte circadian clock modulates responsiveness of the heart to hypertrophic stimuli in mice. Chronobiol Int. 28:187–203. doi:10.3109/07420528.2010.550406.
  • Durgan DJ, Young ME. 2010. The cardiomyocyte circadian clock: Emerging roles in health and disease. Circ Res. 106:647–58. doi:10.1161/CIRCRESAHA.109.209957.
  • Dussault AA, Pouliot M. 2006. Rapid and simple comparison of messenger RNA levels using real-time PCR. Biol Proced Online. 8:1–10. doi:10.1251/bpo114.
  • Emery P, Reppert SM. 2004. A rhythmic Ror. Neuron. 43:443–46. doi:10.1016/j.neuron.2004.08.009.
  • Fahrenkrug J, Georg B, Hannibal J, Jorgensen HL. 2017. Hypophysectomy abolishes rhythms in rat thyroid hormones but not in the thyroid clock. J Endocrinol. 233:209–16. doi:10.1530/JOE-17-0111.
  • Floriani C, Gencer B, Collet TH, Rodondi N. 2017. Subclinical thyroid dysfunction and cardiovascular diseases: 2016 update. Eur Heart J. doi:10.1093/eurheartj/ehx050.
  • Guo TY, Liu LJ, Xu LZ, Zhang JC, Li SX, Chen C, He LG, Chen YM, Yang HD, Lu L, et al. 2015. Alterations of the daily rhythms of HPT axis induced by chronic unpredicted mild stress in rats. Endocrine. 48:637–43. doi:10.1007/s12020-014-0314-y.
  • Hak AE, Pols HA, Visser TJ, Drexhage HA, Hofman A, Witteman JC. 2000. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: The Rotterdam Study. Ann Intern Med. 132:270–78. doi:10.7326/0003-4819-132-4-200002150-00004.
  • Jabbar A, Pingitore A, Pearce SH, Zaman A, Iervasi G, Razvi S. 2017. Thyroid hormones and cardiovascular disease. Nat Rev Cardiol. 14:39–55. doi:10.1038/nrcardio.2016.174.
  • Jordan D, Rousset B, Perrin F, Fournier M, Orgiazzi J. 1980. Evidence for circadian variations in serum thyrotropin, 3,5,3ʹ-triiodothyronine, and thyroxine in the rat. Endocrinology. 107:1245–48. doi:10.1210/endo-107-4-1245.
  • Klein I, Ojamaa K. 2001. Thyroid hormone and the cardiovascular system. N Engl J Med. 344:501–09. doi:10.1056/NEJM200102153440707.
  • Kovac J, Husse J, Oster H. 2009. A time to fast, a time to feast: The crosstalk between metabolism and the circadian clock. Mol Cells. 28:75–80. doi:10.1007/s10059-009-0113-0.
  • Kuno-Murata M, Koibuchi N, Fukuda H, Murata M, Chin WW. 2000. Augmentation of thyroid hormone receptor-mediated transcription by Ca2+/calmodulin-dependent protein kinase type IV. Endocrinology. 141:2275–78. doi:10.1210/endo.141.6.7612.
  • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 25:402–08. doi:10.1006/meth.2001.1262.
  • Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC. 2010. Myocardial fatty acid metabolism in health and disease. Physiol Rev. 90:207–58. doi:10.1152/physrev.00015.2009.
  • MacLennan DH, Kranias EG. 2003. Phospholamban: A crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol. 4:566–77. doi:10.1038/nrm1151.
  • Maia AL, Kim BW, Huang SA, Harney JW, Larsen PR. 2005. Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans. J Clin Invest. 115:2524–33. doi:10.1172/JCI25083.
  • Morkin E, Flink IL, Goldman S. 1983. Biochemical and physiologic effects of thyroid hormone on cardiac performance. Prog Cardiovasc Dis. 25:435–64. doi:10.1016/0033-0620(83)90004-X.
  • Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, De Ferranti S, Despres JP, Fullerton HJ, Howard VJ, et al. 2015. Heart disease and stroke statistics–2015 update: A report from the American Heart Association. Circulation. 131:e29–322. doi:10.1161/CIR.0000000000000152.
  • Nelson W, Tong YL, Lee JK, Halberg F. 1979. Methods for cosinor-rhythmometry. Chronobiologia. 6:305–23.
  • Nunes MT, Bianco AC, Migala A, Agostini B, Hasselbach W. 1985. Thyroxine induced transformation in sarcoplasmic reticulum of rabbit soleus and psoas muscles. Z Naturforsch C. 40:726–34.
  • Peliciari-Garcia RA, Previde RM, Nunes MT, Young ME. 2016. Interrelationship between 3,5,3 -triiodothyronine and the circadian clock in the rodent heart. Chronobiol Int. 33:1444–54. doi:10.1080/07420528.2016.1229673.
  • Peliciari-Garcia RA, Zanquetta MM, Andrade-Silva J, Gomes DA, Barreto-Chaves ML, Cipolla-Neto J. 2011. Expression of circadian clock and melatonin receptors within cultured rat cardiomyocytes. Chronobiol Int. 28:21–30. doi:10.3109/07420528.2010.525675.
  • Rakov H, Engels K, Hones GS, Strucksberg KH, Moeller LC, Kohrle J, Zwanziger D, Fuhrer D. 2016. Sex-specific phenotypes of hyperthyroidism and hypothyroidism in mice. Biol Sex Differ. 7:36. doi:10.1186/s13293-016-0089-3.
  • Rohrer D, Dillmann WH. 1988. Thyroid hormone markedly increases the mRNA coding for sarcoplasmic reticulum Ca2+-ATPase in the rat heart. J Biol Chem. 263:6941–44.
  • Romano RM, Bargi-Souza P, Brunetto EL, Goulart-Silva F, Avellar MC, Oliveira CA, Nunes MT. 2013. Hypothyroidism in adult male rats alters posttranscriptional mechanisms of luteinizing hormone biosynthesis. Thyroid: J Am Thyroid Assoc. 23:497–505. doi:10.1089/thy.2011.0514.
  • Shibusawa N, Hollenberg AN, Wondisford FE. 2003. Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation. J Biol Chem. 278:732–38. doi:10.1074/jbc.M207264200.
  • Tadic M, Celic V, Cuspidi C, Ilic S, Zivanovic V, Marjanovic T. 2016a. How does subclinical hyperthyroidism affect right heart function and mechanics? J Ultrasound Med. 35:287–95. doi:10.7863/ultra.15.03054.
  • Tadic M, Cuspidi C, Ilic S, Marjanovic T, Celic V, Trpkovic S. 2016b. Subclinical hyperthyroidism and biatrial function and mechanics: A two- and three-dimensional echocardiographic study. Scand Cardiovasc J. 50:88–98. doi:10.3109/14017431.2015.1136748.
  • Takahashi JS. 2015. Molecular components of the circadian clock in mammals. Diabetes Obes Metab. 17(Suppl 1):6–11. doi:10.1111/dom.2015.17.issue-S1.
  • Wangensteen R, Rodriguez-Gomez I, Perez-Abud R, Quesada A, Montoro-Molina S, Osuna A, Vargas F. 2015. Dietary salt restriction in hyperthyroid rats. Differential influence on left and right ventricular mass. Exp Biol Med (Maywood). 240:113–20. doi:10.1177/1535370214544265.
  • Yasuo S, Watanabe M, Iigo M, Yamamura T, Nakao N, Takagi T, Ebihara S, Yoshimura T. 2006. Molecular mechanism of photoperiodic time measurement in the brain of Japanese quail. Chronobiol Int. 23:307–15. doi:10.1080/07420520500521913.
  • Young ME. 2006. The circadian clock within the heart: Potential influence on myocardial gene expression, metabolism, and function. Am J Physiol Heart Circ Physiol. 290:H1–16. doi:10.1152/ajpheart.00582.2005.
  • Young ME, Razeghi P, Cedars AM, Guthrie PH, Taegtmeyer H. 2001a. Intrinsic diurnal variations in cardiac metabolism and contractile function. Circ Res. 89:1199–208. doi:10.1161/hh2401.100741.
  • Young ME, Razeghi P, Taegtmeyer H. 2001b. Clock genes in the heart: Characterization and attenuation with hypertrophy. Circ Res. 88:1142–50. doi:10.1161/hh1101.091190.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.