Circadian clock disruption aggravates alcohol liver disease in an acute mouse model

References

• Bailey SM. 2018. Emerging role of circadian clock disruption in alcohol-induced liver disease. Am J Physiol Gastrointest Liver Physiol. 315:G364–G373. doi:10.1152/ajpgi.00010.2018
   PubMed Web of Science ®Google Scholar
• Bertola A, Mathews S, Ki SH, Wang H, Gao B. 2013. Mouse model of chronic and binge ethanol feeding (the NIAAA model). Nat Protoc. 8:627–37. doi:10.1038/nprot.2013.032
   PubMed Web of Science ®Google Scholar
• Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 37:911–17. doi:10.1139/y59-099
   PubMedGoogle Scholar
• Bruce VG, Weight F, Pilttendrigh CS. 1960. Resetting the sporulation rhythm in Pilobolus with short light flashes of high intensity. Science (New York, NY). 131:728–30. doi:10.1126/science.131.3402.728
   Google Scholar
• Chaix A, Lin T, Le HD, Chang MW, Panda S. 2019. Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock. Cell Metab. 29:303–319.e304. doi:10.1016/j.cmet.2018.08.004
   PubMed Web of Science ®Google Scholar
• Chalfant JM, Howatt DA, Tannock LR, Daugherty A, Pendergast JS. 2020. Circadian disruption with constant light exposure exacerbates atherosclerosis in male ApolipoproteinE-deficient mice. Sci Rep. 10:9920. doi:10.1038/s41598-020-66834-9
   PubMed Web of Science ®Google Scholar
• Chellappa SL, Vujovic N, Williams JS, Scheer F. 2019. Impact of circadian disruption on cardiovascular function and disease. Trends Endocrinol Metab. 30:767–79. doi:10.1016/j.tem.2019.07.008
   PubMed Web of Science ®Google Scholar
• Clugston RD, Jiang H, Lee MX, Piantedosi R, Yuen JJ, Ramakrishnan R, Lewis MJ, Gottesman ME, Huang LS, Goldberg IJ, et al. 2011. Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: A targeted lipidomic and gene expression study. J Lipid Res. 52:2021–31. doi:10.1194/jlr.M017368
   PubMed Web of Science ®Google Scholar
• Emens JS, Berman AM, Thosar SS, Butler MP, Roberts SA, Clemons NA, Herzig MX, McHill AW, Morimoto M, Bowles NP, et al. 2020. Circadian rhythm in negative affect: Implications for mood disorders. Psychiatry Res. 293:113337. doi:10.1016/j.psychres.2020.113337
   PubMed Web of Science ®Google Scholar
• Filiano AN, Millender-Swain T, Johnson R Jr, Young ME, Gamble KL, Bailey SM. 2013. Chronic ethanol consumption disrupts the core molecular clock and diurnal rhythms of metabolic genes in the liver without affecting the suprachiasmatic nucleus. Plos One. 8:e71684. doi:10.1371/journal.pone.0071684
   PubMed Web of Science ®Google Scholar
• Garcia Regueiro JA, Gibert J, Diaz I. 1994. Determination of neutral lipids from subcutaneous fat of cured ham by capillary gas chromatography and liquid chromatography. J Chromatogr A. 667:225–33. doi:10.1016/0021-9673(94)89071-4
   PubMed Web of Science ®Google Scholar
• Gaucher J, Kinouchi K, Ceglia N, Montellier E, Peleg S, Greco CM, Schmidt A, Forne I, Masri S, Baldi P, et al. 2019. Distinct metabolic adaptation of liver circadian pathways to acute and chronic patterns of alcohol intake. Proc Natl Acad Sci U S A. 116:25250–59. doi:10.1073/pnas.1911189116
   PubMed Web of Science ®Google Scholar
• Ghosh Dastidar S, Warner JB, Warner DR, McClain CJ, Kirpich IA. 2018. Rodent models of alcoholic liver disease: role of binge ethanol administration. Biomolecules. 8:3. doi:10.3390/biom8010003
   PubMed Web of Science ®Google Scholar
• Griffin P, Dimitry JM, Sheehan PW, Lananna BV, Guo C, Robinette ML, Hayes ME, Cedeño MR, Nadarajah CJ, Ezerskiy LA, et al. 2019. Circadian clock protein Rev-erbalpha regulates neuroinflammation. Proc Natl Acad Sci U S A. 116:5102–07. doi:10.1073/pnas.1812405116
   PubMed Web of Science ®Google Scholar
• Kudo T, Tamagawa T, Shibata S. 2009. Effect of chronic ethanol exposure on the liver of clock-mutant mice. J Circadian Rhythms. 7:4. doi:10.1186/1740-3391-7-4
   PubMedGoogle Scholar
• Lamas-Paz A, Hao F, Nelson LJ, Vázquez MT, Canals S, Gómez Del Moral M, Martínez-Naves E, Nevzorova YA, Cubero FJ. 2018. Alcoholic liver disease: utility of animal models. World J Gastroenterol. 24:5063–75. doi:10.3748/wjg.v24.i45.5063
   PubMed Web of Science ®Google Scholar
• Lee SM, Zhang Y, Tsuchiya H, Smalling R, Jetten AM, Wang L. 2015. Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism. Hepatology. 61:497–505. doi:10.1002/hep.27437
   PubMed Web of Science ®Google Scholar
• Ono D, Mukai Y, Hung CJ, Chowdhury S, Sugiyama T, Yamanaka A. 2020. The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus. Sci Adv. 6:eabd0384. doi:10.1126/sciadv.abd0384
   PubMed Web of Science ®Google Scholar
• Pillai JA, Bena J, Bekris LM, Foldvary-Schaefer N, Heinzinger C, Rao S, Rao SM, Leverenz JB, Mehra R. 2021. Unique sleep and circadian rhythm dysfunction neuroinflammatory and immune profiles in alzheimer’s disease with mild cognitive impairment. J Alzheimer’s Dis. 81:487–92. doi:10.3233/JAD-201573
   PubMed Web of Science ®Google Scholar
• Potter G, Wood TR. 2020. The future of shift work: circadian biology meets personalised medicine and behavioural science. Front Nutr. 7:116. doi:10.3389/fnut.2020.00116
   PubMed Web of Science ®Google Scholar
• Schernhammer ESLF, Speizer FE, Willett WC, Hunter DJ, Kawachi I, Fuchs CS, Colditz GA. 2003. Night-shift work and risk of colorectal cancer in the nurses’ health study. J Natl Cancer Inst. 95:825–28. doi:10.1093/jnci/95.11.825
   PubMed Web of Science ®Google Scholar
• Sigurdardottir LG, Valdimarsdottir UA, Fall K, Rider JR, Lockley SW, Schernhammer E, Mucci LA. 2012. Circadian disruption, sleep loss, and prostate cancer risk: A systematic review of epidemiologic studies. Cancer epidemiology, biomarkers & prevention: A publication of the American Association for Cancer Research. Cancer Epidemiol Biomarkers Prev. 21:1002–11. doi:10.1158/1055-9965.EPI-12-0116
   PubMed Web of Science ®Google Scholar
• Sigurdardottir LG, Valdimarsdottir UA, Mucci LA, Fall K, Rider JR, Schernhammer E, Czeisler CA, Launer L, Harris T, Stampfer MJ, et al. 2013. Sleep disruption among older men and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 22:872–79. doi:10.1158/1055-9965.EPI-12-1227-T
   PubMed Web of Science ®Google Scholar
• Sokolove PG, Bushell WN. 1978. The chi square periodogram: Its utility for analysis of circadian rhythms. J Theor Biol. 72:131–60. doi:10.1016/0022-5193(78)90022-X
   PubMed Web of Science ®Google Scholar
• Tsuchiya H, da Costa KA, Lee S, Renga B, Jaeschke H, Yang Z, Orena SJ, Goedken MJ, Zhang Y, Kong B, et al. 2015. Interactions between nuclear receptor SHP and FOXA1 maintain oscillatory homocysteine homeostasis in mice. Gastroenterology. 148:1012–23. doi:10.1053/j.gastro.2015.01.045
   PubMed Web of Science ®Google Scholar
• Udoh US, Swain TM, Filiano AN, Gamble KL, Young ME, Bailey SM. 2015. Chronic ethanol consumption disrupts diurnal rhythms of hepatic glycogen metabolism in mice. Am J Physiol Gastrointest Liver Physiol. 308:G964–G974. doi:10.1152/ajpgi.00081.2015
   PubMed Web of Science ®Google Scholar
• Udoh US, Valcin JA, Swain TM, Filiano AN, Gamble KL, Young ME, Bailey SM. 2018. Genetic deletion of the circadian clock transcription factor BMAL1 and chronic alcohol consumption differentially alter hepatic glycogen in mice. Am J Physiol Gastrointest Liver Physiol. 314:G431–G447. doi:10.1152/ajpgi.00281.2017
   PubMed Web of Science ®Google Scholar
• Valcin JA, Udoh US, Swain TM, Andringa KK, Patel CR, Al Diffalha S, Baker P, Gamble KL, Bailey SM. 2020. Alcohol and liver clock disruption increase small droplet macrosteatosis, alter lipid metabolism and clock gene mRNA rhythms, and remodel the triglyceride lipidome in mouse liver. Front Physiol. 11:1048. doi:10.3389/fphys.2020.01048
   PubMed Web of Science ®Google Scholar
• Wu Y, Tian T, Wu Y, Yang Y, Zhang Y, Qin X. 2021. Systematic studies of the circadian clock genes impact on temperature compensation and cell proliferation using CRISPR tools. Biology. 10:1204. doi:10.3390/biology10111204
   PubMedGoogle Scholar
• Xiao J, Wang F, Wong NK, He J, Zhang R, Sun R, Xu Y, Liu Y, Li W, Koike K, et al. 2019. Global liver disease burdens and research trends: Analysis from a Chinese perspective. J Hepatol. 71:212–21. doi:10.1016/j.jhep.2019.03.004
   PubMed Web of Science ®Google Scholar
• Yang CH, Hwang CF, Chuang JH, Lian WS, Wang FS, Huang EI, Yang MY. 2020a. Constant light dysregulates cochlear circadian clock and exacerbates noise-induced hearing loss. Int J Mol Sci. 21:7535. doi:10.3390/ijms21207535
   PubMed Web of Science ®Google Scholar
• Yang Y, Duguay D, Fahrenkrug J, Cermakian N, Wing SS. 2014. USP2 regulates the intracellular localization of PER1 and circadian gene expression. J Biol Rhythms. 29:243–56. doi:10.1177/0748730414544741
   PubMed Web of Science ®Google Scholar
• Yang Y, Li N, Qiu J, Ge H, Qin X. 2020b. Identification of the repressive domain of the negative circadian clock component CHRONO. Int J Mol Sci. 21:2469. doi:10.3390/ijms21072469
   PubMed Web of Science ®Google Scholar
• Yang Z, Tsuchiya H, Zhang Y, Lee S, Liu C, Huang Y, Vargas GM, Wang L. 2016. REV-ERBalpha activates C/EBP homologous protein to control small heterodimer partner-mediated oscillation of alcoholic fatty liver. Am J Pathol. 186:2909–20. doi:10.1016/j.ajpath.2016.07.014
   PubMed Web of Science ®Google Scholar
• Zhang D, Tong X, Nelson BB, Jin E, Sit J, Charney N, Yang M, Omary MB, Yin L. 2018. The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARalpha pathway. Hepatology. 68:883–96. doi:10.1002/hep.29878
   PubMed Web of Science ®Google Scholar
• Zhou P, Ross RA, Pywell CM, Liangpunsakul S, Duffield GE. 2014. Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis. Sci Rep. 4:3725. doi:10.1038/srep03725
   PubMed Web of Science ®Google Scholar