Circadian variations in the elderly: A scoping review

References

• Acosta-Rodríguez VA, Rijo-Ferreira F, Green CB, Takahashi JS. 2021. Importance of circadian timing for aging and longevity. Nat Commun. 12:2862. doi: 10.1038/s41467-021-22922-6.
   PubMed Web of Science ®Google Scholar
• Barreca T, Franceschini R, Messina V, Bottaro L, Rolandi E. 1985. 24-hour thyroid-stimulating hormone secretory pattern in elderly men. Gerontology. 31:119–123. doi: 10.1159/000212690.
   PubMed Web of Science ®Google Scholar
• Clegg A, Hassan-Smith Z. 2018. Frailty and the endocrine system. Lancet Diabetes Endocrinol. 6:743–752. doi: 10.1016/s2213-8587(18)30110-4.
   PubMed Web of Science ®Google Scholar
• Cugini P, Lucia P, Di Palma L, Re M, Canova R, Gasbarrone L, Cianetti A. 1992a. The circadian rhythm of atrial natriuretic peptide, vasoactive intestinal peptide, beta-endorphin and cortisol in healthy young and elderly subjects. Clin Auton Res. 2:113–118. doi: 10.1007/bf01819666.
   PubMedGoogle Scholar
• Cugini P, Lucia P, Di Palma L, Re M, Canova R, Gasbarrone L, Cianetti A. 1992b. Effect of aging on circadian rhythm of atrial natriuretic peptide, plasma renin activity, and plasma aldosterone. J Gerontol. 47:B214–B219. doi: 10.1093/geronj/47.6.b214.
   PubMedGoogle Scholar
• Cugini P, Lucia P, Tomassini R, Letizia C, Murano G, Scavo D, Tamburrano G, Maldonato A, Halberg F, Schramm A, et al. 1985. Temporal correlation of some endocrine circadian rhythms in elderly subjects. Maturitas. 7:175–186. doi: 10.1016/0378-5122(85)90024-6.
   PubMed Web of Science ®Google Scholar
• Cugini P, Scavo D, Centanni M, Halberg F, Haus E, Lakatua D, Schramm A, Pusch HJ, Franke H, Kawasaky T. 1983. Circadian as well as circannual rhythms of circulating aldosterone have decreased amplitude in aging women. J Endocrinol Invest. 6:17–22. doi: 10.1007/BF03350555.
   PubMed Web of Science ®Google Scholar
• Cugini P, Scavo D, Halberg F, Sothern RB, Cornelissen G, Meucci T, Salandi E, Massimiani F. 1981. Ageing and circadian rhythm of plasma renin and aldosterone. Maturitas. 3:173–182. doi: 10.1016/0378-5122(81)90009-8.
   PubMed Web of Science ®Google Scholar
• Dong D, Yang D, Lin L, Wang S, Wu B. 2020. Circadian rhythm in pharmacokinetics and its relevance to chronotherapy. Biochem Pharmacol. 178:114045. doi: 10.1016/j.bcp.2020.114045.
   PubMed Web of Science ®Google Scholar
• Duffy JF, Scheuermaier K, Loughlin KR. 2016. Age-related sleep disruption and reduction in the circadian rhythm of urine output: contribution to nocturia? Curr Aging Sci. 9:34–43. doi: 10.2174/1874609809666151130220343.
   PubMedGoogle Scholar
• Duffy JF, Zeitzer JM, Rimmer DW, Klerman EB, Dijk D-J, Czeisler CA. 2002. Peak of circadian melatonin rhythm occurs later within the sleep of older subjects. Am J Physiol-Endoc M. 282:E297–E303. doi: 10.1152/ajpendo.00268.2001.
   PubMed Web of Science ®Google Scholar
• Fabbri E, An Y, Gonzalez-Freire M, Zoli M, Maggio M, Studenski SA, Egan JM, Chia CW, Ferrucci L. 2016. Bioavailable testosterone linearly declines over a wide age spectrum in men and women from the baltimore longitudinal study of aging. J Gerontol. 71:1202–1209. doi: 10.1093/gerona/glw021.
   Google Scholar
• Feldman HA, Longcope C, Derby CA, Johannes CB, Araujo AB, Coviello AD, Bremner WJ, McKinlay JB. 2002. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. J Clin Endocr Metab. 87:589–598. doi: 10.1210/jcem.87.2.8201.
   PubMed Web of Science ®Google Scholar
• Forsling ML, Montgomery H, Halpin D, Windle RJ, Treacher DF. 1998. Daily patterns of secretion of neurohypophysial hormones in man: effect of age. Exp Physiol. 83:409–418. doi: 10.1113/expphysiol.1998.sp004124.
   PubMed Web of Science ®Google Scholar
• Franceschini R, Corsini G, Cataldi A, Fiorucci A, Tenerelli P, Rolandi E, Barreca T. 1999. Twenty-four—hour variation in serum leptin in the elderly. Metabolism. 48:1011–1014. doi: 10.1016/S0026-0495(99)90198-1.
   PubMed Web of Science ®Google Scholar
• Franco M, Khorrami Chokami K, Albertelli M, Teti C, Cocchiara F, Gatto F, Trombetta C, Ferone D, Boschetti M. 2023. Modulatory activity of testosterone on growth pattern and IGF-1 levels in vanishing testis syndrome: a case report during 15 years of follow-up. BMC Endocr Disord. 23:13. doi: 10.1186/s12902-022-01258-2.
   PubMed Web of Science ®Google Scholar
• Gamble KL, Berry R, Frank SJ, Young ME. 2014. Circadian clock control of endocrine factors. Nat Rev Endocrinol. 10:466–475. doi: 10.1038/nrendo.2014.78.
   PubMed Web of Science ®Google Scholar
• Gekakis N, Staknis D, Nguyen HB, Davis FC, Wilsbacher LD, King DP, Takahashi JS, Weitz CJ. 1998. Role of the CLOCK protein in the mammalian circadian mechanism. Science. 280:1564–1569. doi: 10.1126/science.280.5369.1564.
   PubMed Web of Science ®Google Scholar
• Gharahdaghi N, Phillips BE, Szewczyk NJ, Smith K, Wilkinson DJ, Atherton PJ. 2021. Links between testosterone, oestrogen, and the growth hormone/insulin-like growth factor axis and resistance exercise muscle adaptations. Front Physiol. 11. doi: 10.3389/fphys.2020.621226.
   Web of Science ®Google Scholar
• Gnocchi D, Bruscalupi G. 2017. Circadian rhythms and hormonal homeostasis: pathophysiological implications. Biology. 6:10. doi: 10.3390/biology6010010.
   PubMedGoogle Scholar
• Godfrey S, Iversen HK, West AS. 2022. Melatonin profile in healthy, elderly subjects - a systematic literature review. Chronobiol Int. 39:476–492. doi: 10.1080/07420528.2021.2016794.
   PubMed Web of Science ®Google Scholar
• Guagnano MT, Del Ponte A, Rosaria Manigrasso M, Merlitti D, Pace-Palitti V, Sensi S. 2001. Age-related circadian rhythm of DHEAS plasma levels in male subjects. Biol Rhythm Res. 32:323–331. doi: 10.1076/brhm.32.3.323.1347.
   Web of Science ®Google Scholar
• Guo H, Brewer JM, Lehman MN, Bittman EL. 2006. Suprachiasmatic regulation of circadian rhythms of gene expression in hamster peripheral organs: effects of transplanting the pacemaker. J Neurosci. 26:6406–6412. doi: 10.1523/jneurosci.4676-05.2006.
   PubMed Web of Science ®Google Scholar
• Hood S, Amir S. 2017. The aging clock: circadian rhythms and later life. J Clin Invest. 127:437–446. doi: 10.1172/JCI90328.
   PubMed Web of Science ®Google Scholar
• Iranmanesh A, Lizarralde G, Veldhuis JD. 1991. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous gh in healthy men*. J Clin Endocr Metab. 73:1081–1088. doi: 10.1210/jcem-73-5-1081.
   PubMed Web of Science ®Google Scholar
• Joseph F, Chan BY, Durham BH, Ahmad AM, Vinjamuri S, Gallagher JA, Vora JP, Fraser WD. 2007. The circadian rhythm of osteoprotegerin and its association with parathyroid hormone secretion. J Clin Endocr Metab. 92:3230–3238. doi: 10.1210/jc.2006-1832.
   PubMed Web of Science ®Google Scholar
• Koronowski KB, Sassone-Corsi P. 2021. Communicating clocks shape circadian homeostasis. Science. 371:eabd0951. doi: 10.1126/science.abd0951.
   PubMed Web of Science ®Google Scholar
• Leng Y, Blackwell T, Cawthon PM, Ancoli-Israel S, Stone K, Yaffe K. 2020. 1145 longitudinal association between circadian activity rhythms and risk of incident Parkinson’s disease in older men. Sleep. 43:A436–A436. doi: 10.1093/sleep/zsaa056.1139.
   Web of Science ®Google Scholar
• Mahlberg R, Tilmann A, Salewski L, Kunz D. 2006. Normative data on the daily profile of urinary 6-sulfatoxymelatonin in healthy subjects between the ages of 20 and 84. Psychoneuroendocrinology. 31:634–641. doi: 10.1016/j.psyneuen.2006.01.009.
   PubMed Web of Science ®Google Scholar
• Mattis J, Sehgal A. 2016. Circadian rhythms, sleep, and disorders of aging. Trends In Endocrinol Metabolism. 27:192–203. doi: 10.1016/j.tem.2016.02.003.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, Carughi S, Sperandeo M, Pazienza V, Giuliani F, Greco A. 2011a. Alteration of circadian rhythmicity of CD3+CD4+ lymphocyte subpopulation in healthy aging. J Biol Regul Homeost Agents. 25:405–416.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, Correra M, Bianco G, De Cata A, Balzanelli M, Giuliani A, Tarquini R. 1997. Age-related changes of neuro-endocrine-immune interactions in healthy humans. J Biol Regul Homeost Agents. 11:143–147.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, De Cata A, Carughi S, Greco A, Inglese M, Perfetto F, Tarquini R. 2010a. A possible mechanism for altered immune response in the elderly. Vivo. 24:471.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, De Cata A, Greco A, Damato M, Marzulli N, Dagostino MP, Carughi S, Perfetto F, Tarquini R. 2010b. Aging related changes of circadian rhythmicity of cytotoxic lymphocyte subpopulations. J Circadian Rhythms. 25:6. doi: 10.1186/1740-3391-8-6.
   Google Scholar
• Mazzoccoli G, Inglese M, Dagostino MP, Piepoli A, Muscarella LA, Pazienza V, Tarquini R, Giuliani F. 2011b. Age-related changes of GH-IGF1 axis function. Biomed Aging Pathol. 1:39–45. doi: 10.1016/j.biomag.2010.10.002.
   Google Scholar
• Mazzoccoli G, Inglese M, De Cata A, Carughi S, Dagostino MP, Marzulli N, Damato M, Grilli M, Giuliani F, Greco A. 2011c. Neuroendocrine-immune interactions in healthy aging. Geriatr Gerontol Int. 11:98–106. doi: 10.1111/j.1447-0594.2010.00628.x.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, Pazienza V, Piepoli A, Muscarella LA, Inglese M, De Cata A, Giuliani F, Tarquini R. 2010c. Hypothalamus-hypophysis-thyroid axis function in healthy aging. J Biol Regul Homeost Agents. 24:433–439.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, Vendemiale G, De Cata A, Tarquini R. 2011d. Change of γδTCR-Expressing T cells in healthy aging. Int J Immunopathol Pharmacol. 24:201–209. doi: 10.1177/039463201102400124.
   PubMed Web of Science ®Google Scholar
• Mazzoccoli G, Vendemiale G, Inglese M, De Cata A, Piepoli A, Pazienza V, Muscarella LA, Tarquini R. 2011e. Neuroendocrine axes function in healthy aging: evaluation of predictive and manipulable blood serum indexes. Biomed Aging Pathol. 1:16–21. doi: 10.1016/j.biomag.2010.09.002.
   Google Scholar
• Mazzoccoli G, Vendemiale G, La Viola M, De Cata A, Carughi S, Greco A, Balzanelli M, Tarquini R. 2010d. Circadian variations of cortisol, melatonin and lymphocyte subpopulations in geriatric age. Int J Immunopathol Pharmacol. 23:289–296. doi: 10.1177/039463201002300127.
   PubMed Web of Science ®Google Scholar
• Mistry P, Duong A, Kirshenbaum L, Martino TA. 2017. Cardiac clocks and preclinical translation. Heart Fail Clin. 13:657–672. doi: 10.1016/j.hfc.2017.05.002.
   PubMed Web of Science ®Google Scholar
• Montanini V, Simoni M, Chiossi G, Baraghini GF, Velardo A, Baraldi E, Marrama P. 1988. Age-related changes in plasma dehydroepiandrosterone sulphate, cortisol, testosterone and free testosterone circadian rhythms in adult men. Horm Res. 29:1–6. doi: 10.1159/000180956.
   PubMed Web of Science ®Google Scholar
• Nair NPV, Hariharasubramanian N, Pilapil C, Isaac I, Thavundayil JX. 1986. Plasma melatonin—an index of brain aging in humans? Biol Psychiatry. 21:141–150. doi: 10.1016/0006-3223(86)90141-1.
   PubMed Web of Science ®Google Scholar
• Nater UM, Rohleder N, Schlotz W, Ehlert U, Kirschbaum C. 2007. Determinants of the diurnal course of salivary alpha-amylase. Psychoneuroendocrinology. 32:392–401. doi: 10.1016/j.psyneuen.2007.02.007.
   PubMed Web of Science ®Google Scholar
• Ohashi Y, Okamoto N, Uchida K, Iyo M, Mori N, Morita Y. 1997. Differential pattern of the circadian rhythm of serum melatonin in young and elderly healthy subjects. Biol Signals. 6:301–306. doi: 10.1159/000109141.
   PubMedGoogle Scholar
• Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, Schultz PG, Kay SA, Takahashi JS, Hogenesch JB. 2002. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell. 109:307–320. doi: 10.1016/S0092-8674(02)00722-5.
   PubMed Web of Science ®Google Scholar
• Pick R, He W, Chen C-S, Scheiermann C. 2019. Time-of-day-dependent trafficking and function of leukocyte subsets. Trends Immunol. 40:524–537. doi: 10.1016/j.it.2019.03.010.
   PubMed Web of Science ®Google Scholar
• Pilgrim AL, Robinson SM, Sayer AA, Roberts HC. 2015. An overview of appetite decline in older people. Nurs Older People. 27:29–35. doi: 10.7748/nop.27.5.29.e697.
   PubMedGoogle Scholar
• Pina GDMS, Mota Carvalho R, Silva BSDF, Almeida FT. 2020. Prevalence of hyposalivation in older people: A systematic review and meta-analysis. Gerodontology. 37:317–331. doi: 10.1111/ger.12497.
   PubMed Web of Science ®Google Scholar
• Plymate SR, Tenover JS, Bremner WJ. 1989. Circadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men. J Androl. 10:366–371. doi: 10.1002/j.1939-4640.1989.tb00120.x.
   PubMed Web of Science ®Google Scholar
• Prinz PN, Halter J, Benedetti C, Raskind M. 1979. Circadian variation of plasma catecholamines in young and old men: Relation to rapid eye movement and slow wave sleep. J Clin Endocr Metab. 49:300–304. doi: 10.1210/jcem-49-2-300.
   PubMed Web of Science ®Google Scholar
• Ramsay S, Zagorodnyuk V. 2023. Role of circadian rhythms and melatonin in bladder function in heath and diseases. Auton Neurosci. 246:103083. doi: 10.1016/j.autneu.2023.103083.
   PubMed Web of Science ®Google Scholar
• Roenneberg T, Kuehnle T, Juda M, Kantermann T, Allebrandt K, Gordijn M, Merrow M. 2007. Epidemiology of the human circadian clock. Sleep Med Rev. 11:429–438. doi: 10.1016/j.smrv.2007.07.005.
   PubMed Web of Science ®Google Scholar
• Rolandi E, Franceschini R, Cataldi A, Barreca T. 1990. Twenty-four-hour secretory pattern of vasoactive intestinal polypeptide in the elderly. Gerontology. 36:356–360. doi: 10.1159/000213221.
   PubMed Web of Science ®Google Scholar
• Rolandi E, Franceschini R, Marabini A, Messina V, Cataldi A, Salvemini M, Barreca T. 1987. Twenty-four-hour beta-endorphin secretory pattern in the elderly. Acta Endocrinol (Copenh). 115:441–446. doi: 10.1530/acta.0.1150441.
   PubMedGoogle Scholar
• Sharma M, Palacios-Bois J, Schwartz G, Iskandar H, Thakur M, Quirion R, Nair NPV. 1989. Circadian rhythms of melatonin and cortisol in aging. Biol Psychiatry. 25:305–319. doi: 10.1016/0006-3223(89)90178-9.
   PubMed Web of Science ®Google Scholar
• Singh R, Sharma S, Singh RK, Cornelissen G. 2016. Circadian time structure of circulating plasma lipid components in healthy Indians of different age groups. Indian J Clin Biochem. 31:215–223. doi: 10.1007/s12291-015-0519-8.
   PubMed Web of Science ®Google Scholar
• Soulban G, Labrecque G, Barbeau G. 1995. Time-dependent variations in the coagulation factors II, VII, IX, and X in young and elderly volunteers. Chronobiol Int. 12:206–213. doi: 10.3109/07420529509057267.
   Web of Science ®Google Scholar
• Steele TA, St Louis EK, Videnovic A, Auger RR. 2021. Circadian rhythm sleep–wake disorders: a contemporary review of neurobiology, treatment, and dysregulation in neurodegenerative disease. Neurotherapeutics. 18:53–74. doi: 10.1007/s13311-021-01031-8.
   PubMed Web of Science ®Google Scholar
• Swoyer J, Irvine P, Sackett-Lundeen L, Conlin L, Lakatua DJ, Haus E. 1989. Circadian hematologic time structure in the elderly. Chronobiol Int. 6:131–137. doi: 10.3109/07420528909064623.
   PubMed Web of Science ®Google Scholar
• Tenover JS, Bremner WJ. 1991. Circadian rhythm of serum immunoreactive inhibin in young and elderly men. J Gerontol. 46:M181–184. doi: 10.1093/geronj/46.5.m181.
   PubMedGoogle Scholar
• Tenover JS, Matsumoto AM, Clifton DK, Bremner WJ. 1988. Age-related alterations in the circadian rhythms of pulsatile luteinizing hormone and testosterone secretion in healthy men. J Gerontol. 43:M163–M169. doi: 10.1093/geronj/43.6.m163.
   PubMedGoogle Scholar
• Töbelmann D, Dittmar M. 2021. Diurnal relationship between core clock gene BMAL1, antioxidant SOD1 and oxidative RNA/DNA damage in young and older healthy women. Exp Gerontol. 151:111422. doi: 10.1016/j.exger.2021.111422.
   PubMed Web of Science ®Google Scholar
• Touitou Y, Touitou C, Bogdan A, Reinberg A, Motohashi Y, Auzéby A, Beck H. 1989. Circadian and seasonal variations of electrolytes in aging humans. Clin Chim Acta. 180:245–253. doi: 10.1016/0009-8981(89)90006-5.
   PubMed Web of Science ®Google Scholar
• Trotti R, Rondanelli M, Cuzzoni G, Magnani B, Gabanti E, Ferrari E. 2003. Circadian organization of serum electrolytes in physiological aging. Funct Neurol. 18:77–81.
   PubMed Web of Science ®Google Scholar
• Tsimakouridze EV, Alibhai FJ, Martino TA. 2015. Therapeutic applications of circadian rhythms for the cardiovascular system. Front Pharmacol. 6. doi: 10.3389/fphar.2015.00077.
   PubMed Web of Science ®Google Scholar
• Turcu AF, Zhao L, Chen X, Yang R, Rege J, Rainey WE, Veldhuis JD, Auchus RJ. 2021. Circadian rhythms of 11-oxygenated C19 steroids and ∆5-steroid sulfates in healthy men. Eur J Endocrinol. 185:K1–K6. doi: 10.1530/eje-21-0348.
   PubMed Web of Science ®Google Scholar
• Uchida K, Okamoto N, Ohara K, Morita Y. 1996. Daily rhythm of serum melatonin in patients with dementia of the degenerate type. Brain Res. 717:154–159. doi: 10.1016/0006-8993(96)00086-8.
   PubMed Web of Science ®Google Scholar
• Van Coevorden A, Laurent E, Decoster C, Kerkhofs M, Neve P, Van Cauter E, Mockel J. 1989. Decreased basal and stimulated thyrotropin secretion in healthy elderly men*. J Clin Endocr Metab. 69:177–185. doi: 10.1210/jcem-69-1-177.
   PubMed Web of Science ®Google Scholar
• van Coevorden A, Mockel J, Laurent E, Kerkhofs M, L’Hermite-Balériaux M, Decoster C, Nève P, Van Cauter E. 1991. Neuroendocrine rhythms and sleep in aging men. Am J Physiol. 260:E651–E661. doi: 10.1152/ajpendo.1991.260.4.E651.
   PubMed Web of Science ®Google Scholar
• van den Beld AW, Kaufman J-M, Zillikens MC, Lamberts SWJ, Egan JM, van der Lely AJ. 2018. The physiology of endocrine systems with ageing. Lancet Diabetes Endocrinol. 6:647–658. doi: 10.1016/S2213-8587(18)30026-3.
   PubMed Web of Science ®Google Scholar
• Wang C, Lutes LK, Barnoud C, Scheiermann C. 2022. The circadian immune system. Sci Immunol. 7:eabm2465. doi: 10.1126/sciimmunol.abm2465.
   PubMed Web of Science ®Google Scholar
• Wyse C, O’Malley G, Coogan AN, McConkey S, Smith DJ. 2021. Seasonal and daytime variation in multiple immune parameters in humans: evidence from 329,261 participants of the UK biobank cohort. iScience. 24:102255. doi: 10.1016/j.isci.2021.102255.
   PubMed Web of Science ®Google Scholar
• Zeitzer JM, Daniels JE, Duffy JF, Klerman EB, Shanahan TL, Dijk D-J, Czeisler CA. 1999. Do plasma melatonin concentrations decline with age? Am J Med. 107:432–436. doi: 10.1016/S0002-9343(99)00266-1.
   PubMed Web of Science ®Google Scholar
• Zheng L, Seon YJ, McHugh J, Papagerakis S, Papagerakis P. 2012. Clock genes show circadian rhythms in salivary glands. J Dent Res. 91:783–788. doi: 10.1177/0022034512451450.
   PubMed Web of Science ®Google Scholar