The Peptidergic Brain-Gut Axis: Influence on Gastric Ulcer Formation

References

• Grijalva C., Londholm E., Novin D. Physiological and morphological changes in the gastrointestinal tract induced by hypothalamic intervention: an overview. Brain Res Bull 1980; 5: 19–31
   PubMed Web of Science ®Google Scholar
• Cushing H. Peptic ulcers and the interbrain. Surg Gynecol Obstet 1932; 55: 1–34
   Google Scholar
• Henke P. G. The telencephalic limbic system and experimental gastric pathology: a review. Neurosci Biobehav Rev 1982; 6: 381–390
   PubMedGoogle Scholar
• Weiner H., Novin D., Grijalva C. V., Tache Y., Garrick T. Neurobiologic and psychobiologic mechanisms in gastric function and ulceration. West J Med 1985; 143: 207–222
   PubMedGoogle Scholar
• Grijalva C., Tache Y., Gunion M., Walsh J., Geiselman P. Amygdaloid lesions attenuate neurogenic gastric mucosal erosions but do not alter gastric secretory changes induced by intracisternal bombesin. Brain Res Bull 1986; 16: 55–62
   PubMedGoogle Scholar
• McCutcheon N. B., Guile M. N., McCormick R. Electrical stimulation of the medial forebrain bundle-posterior lateral hypothalamus attenuates gastric lesions. Physiol Behav 1986; 37: 435–440
   PubMedGoogle Scholar
• Krieger D. Brain peptides: what, where, and why?. Science 1983; 222: 975–985
   PubMed Web of Science ®Google Scholar
• Tache Y. Nature and biological actions of gastrointestinal peptides: current status. Clin Biochem 1984; 17: 77–81
   PubMedGoogle Scholar
• Tache Y., Simard P., Collu R. Prevention by bombesin of cold-restraint stress-induced hemorrhagic lesions in rats. Life Sci 1979; 24: 1719–1726
   PubMed Web of Science ®Google Scholar
• Maeda-Hagiwara M., Watanabe H., Watanabe K. Enhancement by intracerebroventricular thyrotropin-releasing hormone of indomethacin-induced gastric lesions in the rat. Br J Pharmacol 1983; 80: 725–739
   Google Scholar
• Nakane T., Kanie N., Audhya T., Hollander C. The effects of centrally administered neuropeptides on the development of gastric lesions in the rat. Life Sci 1985; 36: 1197–1203
   PubMed Web of Science ®Google Scholar
• Goto Y., Tache Y. Gastric erosions induced by intracisternal thyrotropin-releasing hormone (TRH) in rats. Peptides 1985; 6: 153–156
   PubMed Web of Science ®Google Scholar
• Maeda-Hagiwara M., Watanabe H. Intracerebroventricular injection of a TRH analog, y-butyrolactone-y-carbonyl-L-histidyl-prolinamide, induces gastric lesions and gastric acid stimulation in rats. Naunyn Schmiedebergs Arch Pharmacol 1985; 33: 142–146
   Google Scholar
• Meisenberg G., Simmons W. H. Peptides and the blood-brain barrier. Life Sci 1983; 32: 2611–2623
   PubMedGoogle Scholar
• Tache Y., Maeda-Hagiwara M., Goto Y., Garrick T. Central nervous system action of TRH to stimulate gastric function and ulceration. Peptides [Suppl], (in press).
   Google Scholar
• Tache Y., Goto Y., Hamel D., Pekary A., Novin D. Mechanisms underlying intracisternal TRH-induced stimulation of gastric acid secretion in rats. Regul Pept 1985; 13: 21–30
   PubMedGoogle Scholar
• Somiya H., Tonoue T. Neuropeptides as central integrators of autonomic nerve activity: effects of TRH, SRIF, VIP and bombesin on gastric and adrenal nerves. Regul Pept 1984; 9: 47–52
   PubMedGoogle Scholar
• Williams A., Hichey E. Synergism between acid and gastric contractile activity in the genesis of ulceration and hemorrhage in the phenylbutazone-treated rat. Surgery 1981; 901: 516–522
   Google Scholar
• Garrick T., Buack S., Bass P. Gastric motility is a major factor in cold restraint-induced lesion formation in rats. Am J Physiol 1986; 250: G191–G199
   Google Scholar
• Takagi A., Mizuta K., Moriga M., Aono M., Uchino H. Effects of gut hormones on gastric mucosal blood flow in rats. Gastrointestinal Function: Proc. of the First Symp. on the Regulation and Disturbances of Gastrointestinal Function, Tokyo, September 1982. Excerpta Medica, Amsterdam, 139–144, Y. Kasuya, M. Tsuchiy, F. Nagao, Y. Matsuo, 1983
   Google Scholar
• Sharif N., Burt D. Limbic, hypothalamic, cortical and spinal regions are enriched in receptors for thyrotropin- releasing hormone: evidence from [3H] ultrafilm autoradiography and correlation with central effects of the tripeptide in rat brain. Neurosci Lett 1985; 60: 337–342
   PubMedGoogle Scholar
• Kreider M. S., Engber T. M., Nilaber G., Zimmerman E., Winokur A. Immunohistochemical localization of TRH in rat CNS: comparison with RIA studies. Peptides 1985; 6: 997–1000
   PubMedGoogle Scholar
• Kubek M., Rea M., Hodes Z., Aprison M. Quantitation and characterization of thyrotropin-releasing hormone in vagal nuclei and other regions of the medulla oblongata of the rat. J Neurochem 1983; 40: 1307–1313
   PubMed Web of Science ®Google Scholar
• Palkovits M., Mezey E., Eskay R., Brownstein M. Innervation of the nucleus of the solitary tract and the dorsal vagal nucleus by thyrotropin-releasing hormone-containing raphe neurons. Brain Res 1986; 373: 246–251
   PubMed Web of Science ®Google Scholar
• Rogers R., Hermann. Vagal afferent stimulation-evoked gastric secretion suppressed by paraventricular nucleus lesion. J Auton Nerv Syst 1985; 13: 191–199
   PubMedGoogle Scholar
• Arancibia S., Tapia-Arancibia L., Assenmacher I., Astier H. Direct evidence of short-term cold-induced TRH release in the median eminence of unanesthetized rats. Neuroendocrinology 1983; 37: 225–228
   PubMedGoogle Scholar
• Senay E., Levine R. Synergism between cold and restraint for rapid production of stress ulcers in rats. Proc Soc Fxp Biol Med 1967; 124: 1221–1223
   PubMed Web of Science ®Google Scholar
• Ackerman S. H. Premature weaning, thermoregulation, and the occurrence of gastric pathology. Brain, Behavior and Bodily Disease, H. Weiner, M. A. Hofer, A. J. Stunkard. Raven Press, New York 1981; 67–86
   Google Scholar
• Bagarani M., Goto Y., Debas H., Basso N. Effect of TRH and TRH antiserum on ulcer formation. Dig Dis Sci 1984; 29: 7S
   Google Scholar
• Hernandez D. E. Neuroendocrine mechanisms of stress ulceration: focus on thyrotropin-releasing hormone (TRH). Life Sci 1986; 39: 279–296
   PubMedGoogle Scholar
• Hernandez D., Nemeroff C., Orlando R., Prange A., Jr. The effect of centrally administered neuropeptides on the development of stress-induced gastric ulcers in rats. J Neurosci Res 1983; 9: 145–157
   PubMed Web of Science ®Google Scholar
• Tache Y. Central nervous system action of neuropeptides to induce or prevent experimental gastroduodenal ulcerations. Perspect Behav Med 1986; 5, (in press.
   Google Scholar
• Hernandez D. E., Adcock J. W. R. C., Nemeroff C. B., Prange A. J., Jr. Influence of brain peptides on the development of stress gastric ulcers. New Pharmacology of Ulcer Disease—Experimental and Therapeutic Approaches, S. Szabo, Moszik. Orlando. 1986, (in press.
   Google Scholar
• Nemeroff C., Hernandez D., Orlando R., Prange A., Jr. Cytoprotective effect of centrally administered neurotensin on stress-induced gastric ulcers. Am J Physiol 1982; 242: G342–G346
   Google Scholar
• Hagiwara M., Watanabe H., Kanoaka R. Effects of intracerebroventricular bombesin on gastric ulcers and gastric glycoproteins in rats. J Pharmacobiodyn 1985; 8: 864–867
   PubMedGoogle Scholar
• Herandez D., Adcock J., Nemeroff C., Prange A. J. The effect of intracisternally administered bombesin on cysteamine-induced duodenal ulcers in rats. Eur J Pharmacol 1982; 84: 205–209
   PubMedGoogle Scholar
• Lesiege D., Tache Y. Inhibition of gastric acid secretion by intracisternal bombesin in rats, independence from interaction with prostaglandins. Gastroenterology 1983; 84: 1228
   Google Scholar
• Tache Y., Gunion M. Central nervous system action of bombesin to inhibit gastric acid secretion. Life Sci 1985; 37: 115–123
   PubMed Web of Science ®Google Scholar
• Tache Y., Brown M., Collu R. Central nervous system actions of bombesin-like peptides. Brain Neurotransmitters and Hormones, R. Collu, J. R. Ducharmes, A. Barbeau, G. Tolis. Raven Press, New York 1982; 183–196
   Google Scholar
• Porreca F., Burks T., Koslo R. Centrally-mediated bombesin effects on gastrointestinal motility. Life Sci 1985; 37: 125–134
   PubMedGoogle Scholar
• Tache Y. Bombesin: central nervous system action to increase gastric mucus in rats. Gastroenterology 1982; 83: 75–80
   PubMedGoogle Scholar
• Morley J., Levine A., Silvis S. Intraventricular calcitonin inhibits gastric acid secretion. Science 1981; 214: 671–673
   PubMed Web of Science ®Google Scholar
• KaulTman G., Kolve E., Hagiwara M., Tache Y. Central nervous system action of calcitonin to influence experimental gastroduodenal ulcers in rats. Gastroenterology 1986; 90: 1486
   Google Scholar
• Maeda-Hagiwara M., Watanabe H., Kanaoka R., Watanabe K. Effects of calcitonin on the gastric mucosa in the rat. New Pharmacology of Ulcer Disease: Experimental and New Therapeutic Approaches, S. Szabo, G. Mozsik. Praeger, Boston 1986
   Google Scholar
• Fischer J. A., Sagar S. M., Martin J. B. Characterization and regional distribution of calcitonin binding sites in the rat brain. Life Sci 1981; 29: 663–671
   PubMedGoogle Scholar
• Rosenfeld M., Mermod J.-J., Amar S., Swanson L., Sawchenko P., Rivier J., Vale W., Evans R. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 1983; 304: 129–135
   PubMed Web of Science ®Google Scholar
• Tache Y., Goto Y., Gunion M., Vale W., Rivier J., Brown M. Inhibition of gastric acid secretion in rats by intracerebral injection of corticotropin-releasing factor. Science 1983; 222: 935–937
   PubMed Web of Science ®Google Scholar
• Krahn D. D., Wright B., Billington C. J., Levine A. S. Exogenous corticotropin-releasing factor inhibits stress- induced gastric ulceration. Soc Neurosci 1986; 12: 1063
   Google Scholar
• Gunion M. W., Tache Y. Gastric mucosal damage is inhibited by intraventromedial hypothalamic corticotrophin releasing factor. Soc Neurosci 1986; 12: 644
   Google Scholar
• Tache Y., Maeda-Hagiwara M., Turkelson C. Central nervous system action of corticotropin-releasing factor to inhibit gastric emptying in rats. Am J Physiol, (in press).
   Google Scholar
• Gunion M., Tache Y., Kauffman G. Intrahypothalamic corticotropin-releasing factor (CRF) increases gastric bicarbonate content. Gastroenterology 1985; 88: 1407
   Google Scholar
• Morley J., Levine A., Silvis S. Endogenous opiates and stress ulceration. Life Sci 1982; 31: 693–699
   PubMedGoogle Scholar
• Ferri S., Arrigo-Reina R., Candeletti S., Costa G., Murari G., Speroni E., Scoto G. Central and peripheral sites of action for the protective effect of opioids of the rat stomach. Pharmacol Res Commun 1983; 15: 4409–418
   Google Scholar
• Adcock J., Hernandez D., Nemeroff C., Prange A., Jr. Effect of prostaglandin synthesis inhibitors on neurotensin and sodium salicylate-induced gastric cytoprotection in rats. Life Sci 1983; 32: 2905–2910
   PubMedGoogle Scholar
• Orlando R., Hernandez D., Prange A., Jr., Nemeroff C. Role of the autonomic nervous system in the cyto-protective effect of neurotensin against gastric stress ulcers in rats. Psychoneuroendocrinology 1985; 10: 149–157
   PubMedGoogle Scholar
• Ackerman S. H., Shindledecker R. D. Chronobiologic factors in experimental stress ulcer. Chronobiol Int 1987; 4: 3–9
   PubMedGoogle Scholar
• Olson C. E., Soil A. H., Guth P. H. Orcadian variation of susceptibility to gastric mucosal injury by acidified aspirin or absolute ethanol in the rat. Gastroenterology 1986; 91: 1192–1197
   PubMed Web of Science ®Google Scholar
• Collu R., DuRuisseau P., Tache Y., Ducharme J. R. Thyrotropin-releasing hormone in rat brain: nyctohemeral variations. Endocrinology 1977; 100: 1391–1393
   PubMedGoogle Scholar
• Martino E., Bambini G., Bartalena L., Aghini-Lombardi F., Breccia M., Baschieri L., Pinchera A. Ontogeny of nyctohemeral variations of thyrotropin-releasing hormone in rat hypothalamus. Endocrinology 1986; 119: 232–235
   PubMedGoogle Scholar
• Nicholson S. A., Adrian T. E., Bacarese-Hamilton A. J., Gillham B., Jones M. T., Bloom S. R. 24-hr variation in content and release of hypothalamic neuropeptides in the rat. Regul Pept 1983; 7: 385–397
   PubMedGoogle Scholar
• Bavon A., Anton B. Diurnal rhythm of the in vivo release of enkephalin from the globus pallidas of the rat. Regul Pept 1986; 15: 63–70
   PubMedGoogle Scholar
• Feldman M., Walker P., Green J. L., Weingarden K. Life events stress and psychosocial factors in men with peptic ulcer disease. Gastroenterology 1986; 91: 1370–1379
   PubMed Web of Science ®Google Scholar