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Articles

Circulating Resistin Is Associated with Plasma Glucagon-Like Peptide-1 in Cirrhotic Patients with Hepatitis C Virus Genotype-4 Infection

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Pages 17-23 | Received 12 Dec 2018, Accepted 31 May 2019, Published online: 10 Jun 2019

References

  • Hoofnagle JH. Course and outcome of hepatitis C. Hepatology. 2002;36:21–29.
  • Sievert W, Altraif I, Razavi HA, et al. Systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt. Liver Int. 2011;31:61–80. doi:10.1111/j.1478-3231.2011.02540.x.
  • Moucari R, Asselah T, Cazals-Hatem D, et al. Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis. Gastroenterology. 2008;13:416–423. doi:10.1053/j.gastro.2007.11.010.
  • Duseja A, Dhiman RK, Chawla Y, et al. Insulin resistance is common in patients with predominantly genotype 3 chronic hepatitis C. Dig Dis Sci. 2009;54:1778–1782. doi:10.1007/s10620-009-0844-y.
  • Hung CH, Lee CM, Lu SN. Hepatitis C virus-associated insulin resistance: pathogenicmechanisms and clinical implications. Expert Rev Anti Infect Ther. 2011;9:525–533. doi:10.1586/eri.11.33.
  • D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol. 2006;44:217–231. doi:10.1016/j.jhep.2005.10.013.
  • Tilg H, Wilmer A, Vogel W, et al. Serum levels of cytokines in chronic liver diseases. Gastroenterology. 1992;103:264–274.
  • Calzadilla-Bertot L, Vilar-Gomez E, Torres-Gonzalez A, et al. Impaired glucose metabolism increases risk of hepatic decompensation and death in patients with compensated hepatitis C virus-related cirrhosis. Dig Liver Dis. 2016;48:283–290. doi:10.1016/j.dld.2015.12.002.
  • Bertolani C, Sancho-Bru P, Failli P, et al. Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells. Am J Pathol. 2006;169:2042–2053. doi:10.2353/ajpath.2006.060081.
  • Kakizaki S, Sohara N, Yamazaki Y, et al. Elevated plasma resistin concentrations in patients with liver cirrhosis. J Gastroenterol Hepatol. 2008;23:73–77. doi:10.1111/j.1440-1746.2006.04757.x.
  • Yagmur E, Trautwein C, Gressner AM, Tacke F. Resistin serum levels are associated with insulin resistance, disease severity, clinical complications, and prognosis in patients with chronic liver diseases. Am J Gastroenterol. 2006;101:1244–1252. doi:10.1111/j.1572-0241.2006.00543.x.
  • Silva TE, Costa-Silva M, Correa CG, et al. Clinical significance of serum adiponectin and resistin levels in liver cirrhosis. Ann Hepatol. 2018;17:286–299. doi:10.5604/01.3001.0010.8660.
  • Pagano C, Soardo G, Pilon C, et al. Increased serum resistin in nonalcoholic fatty liver disease is related to liver disease severity and not to insulin resistance. J Clin Endocrinol Metab. 2006;91:1081–1086. doi:10.1210/jc.2005-1056.
  • Cho YM, Fujita Y, Kieffer TJ. Glucagon-like peptide-1: glucose homeostasis and beyond. Annu Rev Physiol. 2014;76:535–559. doi:10.1146/annurev-physiol-021113-170315.
  • Itou M, Oriishi T, Taniguchi E, Kawaguchi T, Ueno T, Sata M. A gut hormone, glucagon-like peptide-1, associated with HCV-induced insulin resistance. J Hepatol. 2005;42:81–82. Conference poster. doi:10.1016/S0168-8278(05)81621-6.
  • Kruszynska YT, Ghatei MA, Bloom SR, McIntyre N. Insulin secretion and plasma levels of glucose-dependent insulinotropic peptide and glucagon-like peptide 1 [7-36 amide] after oral glucose in cirrhosis. Hepatology. 1995;21:933–941.
  • Junker AE. The role of incretin hormones and glucagon in patients with liver disease. Dan Med J. 2017;64:B53–63.
  • Itou M, Kawaguchi T, Taniguchi EI, et al. Altered expression of glucagon-like peptide −1 and dipeptidyl peptidase IV in patients with HCV-related glucose intolerance. J Gastroenterol Hepatol. 2008;23:244–251. doi:10.1111/j.1440-1746.2007.05183.x.
  • Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of oesophagus or bleeding oesophageal varices. Br J Surg. 1973;60:646–649.
  • Mendenhall CL. Protein-calorie malnutrition in alcoholic liver disease. In: Watson RR, Watzl B, eds. Nutrition and Alcohol. Boca Raton, FL: CRC Press; 1992:363–384.
  • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419.
  • Kamal S, Nassar I. Hepatitis C genotype 4: what we know and what we don’t yet know. Hepatology. 2008;47:1371–1383. doi:10.1002/hep.22127.
  • Egyptian Ministry of Health: Egyptian Ministry of Health Annual Report. 2007.
  • Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology. 2007;132:2131–2157. doi:10.1053/j.gastro.2007.03.054.
  • Yamaoka-Tojo M, Tojo T, Takahira N, et al. Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease. Cardiovasc Diabetol. 2010;9:17. doi:10.1186/1475-2840-9-17.
  • Kahles F, Meyer C, Möllmann J, et al. GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering. Diabetes. 2014;63:3221–3229. doi:10.2337/db14-0100.
  • Piotrowski K, Becker M, Zugwurst J, et al. Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans. Cardiovasc Diabetol. 2013;12:117. doi:10.1186/1475-2840-12-117.
  • Helal TESA, Ehsan NA, Radwan NA, Abdelsameea E. Relationship between hepatic progenitor cells and stellate cells in chronic hepatitis C genotype-4. Apmis. 2018;126:14–20. doi:10.1111/apm.12787.
  • Falkowski O, An HJ, Ianus IA, et al. Regeneration of hepatocyte ‘buds’ in cirrhosis from intrabiliary stem cells. J Hepatol. 2003;39:357–364.
  • Nobili V, Carpino G, Alisi A, et al. Hepatic progenitor cells activation, fibrosis and adipokines production in pediatric nonalcoholic fatty liver disease. Hepatology. 2012;56:2142–2153. doi:10.1002/hep.25742.
  • Nolte W, Hartmann H, Ramadori G. Glucose metabolism and liver cirrhosis. Exp Clin Endocrinol Diabetes. 1995;103:63–74. doi:10.1055/s-0029-1211331.
  • Junker AE, Gluud LL, Holst JJ, Knop FK, Vilsbøll T. Influence of gastrointestinal factors on glucose metabolism in patients with cirrhosis. J Gastroenterol Hepatol. 2015;30:1522–1528. doi:10.1111/jgh.12981.
  • Aulinger BA, Vahl TP, Wilson-Pérez HE, Prigeon RL, D’Alessio DA. β-cell sensitivity to GLP-1 in healthy humans is variable and proportional to insulin sensitivity. J Clin Endocrinol Metab. 2015;100:2489–2496. doi:10.1210/jc.2014-4009.
  • Bahr MJ, Ockenga J, Boker KH, Manns MP, Tietge UJ. Elevated resistin levels in cirrhosis are associated with the proinflammatory state and altered hepatic glucose metabolism but not with insulin resistance. Am J Physiol Endocrinol Metab. 2006;291:E199–E206. doi:10.1152/ajpendo.00359.2005.
  • Kalafateli M, Triantos C, Tsochatzis E, et al. Adipokines levels are associated with the severity of liver disease in patients with alcoholic cirrhosis. World J Gastroenterol. 2015;2:3020–3029. doi:10.3748/wjg.v21.i10.3020.
  • Singla P, Bardoloi A, Parkash A. Metabolic effects of obesity: a review. World J Diabetes. 2010;1:76–88. doi:10.4239/wjd.v1.i3.76.
  • Steppan CM, Wang J, Whiteman EL, Birnbaum MJ, Lazar MA. Activation of SOCS-3 by resistin. Mol Cell Biol. 2005;25:1569–1575. doi:10.1128/MCB.25.4.1569-1575.2005.

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