7
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Inhibition Of Apoptosis In Cultured Immature Rat Leydig Cells By Human Chorionic Gonadotropin Associated With Bcl-2 Mrna Expression

, , , , , & show all
Pages 59-70 | Published online: 07 Aug 2009

References

  • Barr A. B., Moore D. J., Paulsen C. A. Germinal cell loss during human spermatogenesis. J Reprod Fertil 1971; 25: 75–80
  • Troiano L., Flustini M. F., Lovato E., Frusoldati A., Malomi W., Capri M., Grassilli E., Marrama P., Franceschi C. Apoptosis and spermatogenesis evidence from anin vivomodel of testosterone withdrawal in the adult rat. Biochem Biophys Res Commun 1994; 15: 1315–1321
  • Billig H., Furuta I., Rivier C., Tapanainen J., Parvinen M., Hsueh A. JW. Apoptosis in testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages. Endocrinology 1995; 136: 5–12
  • Tapanainen J. S., Tilly J. L., Vihko K. K., Hsueh A. J. Hormonal control of apoptotic cell death in the testes: gonadotropin and androgens as testicular cell survival factors. Mol Endocrinol 1993; 7: 643–650
  • Henriksen K., Hakovirta H., Parvinen M. Testosterone inhibits and induces apoptosis in rat seminiferous tubule in a stage-specific manner:in situquantification in squash preparation after administration of ethane dimethane sulfonate. Endocrinology 1995; 136: 3285–3291
  • Morris A. J., Taylor W., Morris I. D. Leydig cell apoptosis in response to ethane dimethanesulphonate after bothin vivoandin vitrotreatment. J Androl 1997; 18: 274–280
  • Taylor W., Woolveridge I., Metcalfe A. D., Streuli C. H., Hichman J. A., Morris I. D. Leydig cell apoptosis in the rat testes after administration of the cytotoxin ethane dimethanesulphonate; role of the Bcl-2 family members. J Endocrinol 1998; 157: 317–326
  • Russell L. D., Corbin T. J., Ren H. P., Amador A., Bartke A., Ghosh S. Structural changes in rat Leydig cells posthypophysectomy: a morphometric and endocrine study. Endocrinology 1992; 13: 498–508
  • Vaux D. L., Cory S., Adams J. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335: 440–442
  • Hockenbery DK, Zutter M., Hickey W., Nahm M., Korsmeyer S. J. BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA 1991; 88: 6961–6965
  • Reed JC. Bcl-2 and the regulation of programmed cell death. J Cell Biol 1994; 124: 1–6
  • Woolveridge L, de Boer-Brouwer M., Taylor M. F., Teerds K. J., Wu F. C., Morris ID. Apoptosis in the rat spermatogenic epithelium following androgen withdrawal: changes in apoptosis-related genes. Biol Reprod 1999; 60: 461–470
  • Krajewski S., Krajewska M., Shabik A., Miyashita T., Wang H. G., Reed J. C. Immunohistochemical determination ofin vivodistribution of Bax, a dominant inhibitor of Bcl-2. Am J Pathol 1994; 145: 1323–1336
  • Tilly J. L., Tilly K. I., Kenton M. L., Johnson A. L. Expression of members of the bcl-2 gene family in the immature rat ovary: equine chronic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels. Endocrinology 1995; 136: 232–241
  • Kanzaki M., Fujisawa M., Okuda Y., Okada H., Arakawa S., Kamidono S. Expression and regulation of neuropeptide Y messenger ribonucleic acid in cultured immature rat Leydig and Sertoli cells. Endocrinology 1996; 137: 1249–1257
  • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156–159
  • Sato T., Irie S., Krajewski S., Reed J. C. Cloning and sequencing of a cDNA encoding the rat Bcl-2 protein. Gene 1994; 140: 291–292
  • Shikone T., Billig H., Hsueh A. JW. Experimentally induced cryptorchidism increase apoptosis in rat testis. Biol Reprod 1994; 51: 865–872
  • Hikim A. P., Wang C., Leung A., Swerdloff R. S. Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment. Endocrinology 1995; 136: 2770–2775

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.