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Original Article

The Inhibition of Rat Adrenal Cytochrome P-45011β Gene Expression by Androgens

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Pages 145-161 | Published online: 07 Aug 2009

References

  • Skelton F R. Production of hypertension, nephrosclerosis and cardiac lesions by methylandrostenediol treatment in the rat. Endocrinology 1953; 53: 492–505
  • Salgado E., Selye H. The role of the adrenals in the production of cardiovascular and renal changes by methylandrostenediol. Arch. Int. Physiol 1954; 62: 352–358
  • Skelton F R, Brownie A C, Nickerson P A, Molteni A, Gallant S, Colby H D. Adrenal cortical dysfunction as a basis for experimental hypertensive disease. Circ. Res 1969; XXIV-XXV(Suppl.I)I35–I57
  • Grollman A, Harrison T R, Williams J R. The effect of various sterol derivatives on the blood pressure of the rat. J. Pharmacol. Exp. Therap 1940; 69: 149–155
  • Selye H, Hall C E, Rowley E M. Malignant hypertension produced by treatment with desoxycorticosterone acetate and sodium chloride. Can. Med. Ass. J 1943; 49: 88–92
  • Colby H D, Skelton F R, Brownie A C. Testosterone-induced hypertension in the rat. Endocrinology 1970; 86: 1093–1111
  • Molteni A, Brownie A C, Skelton F R. Production of hypertensive vascular disease in the rat by methyltestosterone. Lab. Invest 1969; 21: 129–137
  • Hall C. E., Hungerford S. Similarities and differences between effects of testosterone and 19–nortestosterone in rats, with particular reference to hypertensinogenic potency. J. Steroid. Biochem 1982; 16: 581–585
  • Colby H D, Brownie A C. Effect of androgens on adrenal cortical 11β-hydroxylation. J. Steroid. Biochem 1971; 2: 237–244
  • Kramer R E, Gallant S, Brownie A C. The role of cytochrome P-450 in the action of sodium depletion on aldosterone biosynthesis in rats. J. Biol. Chem 1979; 254: 3953–3958
  • John M E, Simpson E R, Waterman M R, Mason J I. Regulation of cholesterol side-chain cleavage cytochrome P-450 gene expression in adrenal cells in monolayer culture. Mol. Cell. Endocrinol 1986; 45: 197–204
  • Domalik L J, Chaplin D D, Kirkman M S, Wu R C, Liu W, Howard T A, Seldin M F, Parker K L. Different isozymes of mouse 11β-hydroxylase produce mineralocorticoids and glucocorticoids. Molec. Endocrin 1991; 5: 1853–1861
  • Maniatis T, Fritsch E F, Sambrook J. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1982
  • Thomas P S. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 1980; 77: 5201–5205
  • Feinberg A P, Voegelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem 1983; 132: 6–13
  • Sambrook J, Fritsch E F, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd Edition. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1989; 18.8–18.9
  • Nonaka Y, Matsukawa N, Morohashi K -I, Omura T, Ogihara T, Teraoka H, Okamoto M. Molecular cloning and sequence analysis of cDNA encoding rat adrenal cytochrome P-45011β. FEBS Letters 1989; 255: 21–26
  • Bradford M M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem 1976; 72: 248–254
  • Laemmli U K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
  • Towbin H, Staehlin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 1979; 76: 4350–4354
  • Fink C S, Gallant S, Brownie A C. Peripheral serum steroid concentrations in relation to the rat circadian rhythm in androgen-induced hypertension. Hypertension 1980; 2: 617–622
  • McCall A L, Stern J, Dale S L, Melby J C. Adrenal steroidogenesis in methylandrostenediol-induced hypertension. Endocrinology 1978; 103: 1–5
  • Brownie A C, Bhasker C R, Waterman M R. Levels of adrenodoxin, cytochrome P-450 reductase and cytochrome P-45011β, P-45021, P-450scc, in adrenal zona fasciculata-reticularis from androgen-treated rats. Mol. Cell. Endocrinol 1988; 55: 15–20
  • Baker P J, Ramey E R, Ramwell P W. Androgen-mediated sex differences of cardiovascular responses in rats. Amer. J. Physiol 1978; 235: H242–H246
  • Fischer G M, Swain M L. Effect of sex hormones on blood pressure and vascular connective tissue in castrated and noncastrated male rats. Amer. J. Physiol 1977; 232: H617–H621
  • Rembiesa R, Holzbauer M, Young P CM, Birmingham M K, Saffran M. Metabolism of 17α-methylandrostenediol and 17α-methyltestosterone by the rat adrenal gland in vitro. Endocrinology 1967; 81: 1278–1284
  • Calandra R S, Purvis K, Naess O, Attramadal A, Djoseland O, Hansson V. Androgen receptors in the rat adrenal gland. J. Steroid. Biochem 1978; 9: 1009–1015
  • Rifka S M, Cutler G B, Sauer M A, Loriaux D L. Rat adrenal androgen receptor: A possible mediator of androgen-induced decrease in rat adrenal weight. Endocrinology 1978; 103: 1103–1110
  • Kitay J I. Pituitary-adrenal function in the rat after gonadectomy and gonadal hormone replacement. Endocrinology 1963; 73: 253–260
  • Morrow L B, Burrow G N, Mulrow P J. Inhibition of adrenal protein synthesis by steroid in Vitro. Endocrinology 1967; 80: 883–888
  • Hornsby P J. Cytochrome P-450/pseudosubstrate interactions and the role of antioxidants in the adrenal cortex. Endocrine. Res 1986; 12: 469–494
  • Weiner K XB, Dias J A. Protein synthesis is required for testosterone to decrease ornithine decarboxylase messenger RNA levels in rat Sertoli cells. Mol. Endocrinol 1990; 4: 1791–1798

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