REFERENCES
- Alam, M. I., D. S. Coad, and B. Bogacka. 2019. “Combined Criteria for Dose Optimisation in Early Phase Clinical Trials.” Statistics in Medicine 38 (21):4172–88. doi:10.1002/sim.8292
- Bandyopadhyay, U., A. Biswas, and R. Bhattacharya. 2007. “A Covariate Adjusted Two-Stage Allocation Design for Binary Responses in Randomized Clinical Trials.” Statistics in Medicine 26 (24):4386–99. doi:10.1002/sim.2869
- Braun, T. M. 2002. “The Bivariate Continual Reassessment Method: Extending the CRM to Phase I Trials of Two Competing Outcomes.” Controlled Clinical Trials 23 (3):240–56. doi:10.1016/S0197-2456(01)00205-7
- Cheung, Y. K. 2014. “Simple Benchmark for Complex Dose Finding Studies.” Biometrics 70 (2):389–97. doi:10.1111/biom.12158
- Cotterill, A., and T. Jaki. 2018. “Dose-Escalation Strategies Which Use Subgroup Information.” Pharmaceutical Statistics 17 (5):414–36. doi:10.1002/pst.1860
- Cunningham, D., Y. Humblet, S. Siena, D. Khayat, H. Bleiberg, A. Santoro, D. Bets, M. Mueser, A. Harstrick, C. Verslype, et al. 2004. “Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer.” New England Journal of Medicine 351 (4):337–45. doi:10.1056/NEJMoa033025
- Das, I., S. Mukhopadhyay, and H. Xu. 2013. “Individualized Dosing for Multiple Ordered Groups of Patients.” Journal of Statistical Theory and Practice 7 (1):95–106. doi:10.1080/15598608.2013.756348
- Guo, B., and Y. Yuan. 2017. “Bayesian Phase I/II Biomarker-Based Dose Finding for Precision Medicine with Molecularly Targeted Agents.” Journal of the American Statistical Association 112 (518):508–20. doi:10.1080/01621459.2016.1228534
- Mao, X., and Y. K. Cheung. 2017. “Sequential Designs for Individualized Dosing in Phase I Cancer Clinical Trials.” Contemporary Clinical Trials 63:51–8. doi:10.1016/j.cct.2016.08.018
- McCullagh, P., and J. Nelder. 1989. Generalized Linear Models. Chapman and Hall/CRC Monographs on Statistics and Applied Probability Series. 2nd ed. London: Chapman & Hall/CRC.
- Morita, S., P. F. Thall, and K. Takeda. 2017. “A Simulation Study of Methods for Selecting Subgroup-Specific Doses in Phase I Trials.” Pharmaceutical Statistics 16 (2):143–56. doi:10.1002/pst.1797
- O’Quigley, J., M. D. Hughes, and T. Fenton. 2001. “Dose-Finding Designs for HIV Studies.” Biometrics 57 (4):1018–29. doi:10.1111/j.0006-341x.2001.01018.x
- R Core Team. 2013. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing.
- RStudio Team. 2021. RStudio: Integrated Development Environment for R. Boston, MA: RStudio, PBC.
- Thall, P. F., H. Q. Nguyen, and E. H. Estey. 2008. “Patient-Specific Dose Finding Based on Bivariate Outcomes and Covariates.” Biometrics 64 (4):1126–36. doi:10.1111/j.1541-0420.2008.01009.x
- Wathen, J. K., P. F. Thall, J. D. Cook, and E. H. Estey. 2008. “Accounting for Patient Heterogeneity in Phase II Clinical Trials.” Statistics in Medicine 27 (15):2802–15. doi:10.1002/sim.3109
- Wijesinha, M. C., and S. Piantadosi. 1995. “Dose-Response Models with Covariates.” Biometrics 51 (3):977–87. doi:10.2307/2532998
- Zhang, W., D. J. Sargent, and S. Mandrekar. 2006. “An Adaptive Dose-Finding Design Incorporating Both Toxicity and Efficacy.” Statistics in Medicine 25 (14):2365–83. doi:10.1002/sim.2325