A simplified prognostic score for T-cell large granular lymphocyte leukaemia

References

• Shah MV, Hook CC, Call TG, et al. A population-based study of large granular lymphocyte leukemia. Blood Cancer J. 2016;6(8):1–10. doi: 10.1038/bcj.2016.59.
   Google Scholar
• Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375–2390. doi: 10.1182/blood-2016-01-643569.
   PubMed Web of Science ®Google Scholar
• Garrido P, Ruiz-Cabello F, Bárcena P, et al. Monoclonal TCR-Vbeta13.1+/CD4+/NKa+/CD8-/+dim T-LGL lymphocytosis: evidence for an antigen-driven chronic T-cell stimulation origin. Blood. 2007;109(11):4890–4898. doi: 10.1182/blood-2006-05-022277.
   PubMed Web of Science ®Google Scholar
• Lamy T, Moignet A, Loughran TJ. LGL leukemia: from pathogenesis to treatment. Blood. 2017;129(9):1082–1094. doi: 10.1182/blood-2016-08-692590.
   PubMed Web of Science ®Google Scholar
• Coppe A, Andersson EI, Binatti A, et al. Genomic landscape characterization of large granular lymphocyte leukemia with a systems genetics approach. Leukemia. 2017;31(5):1243–1246. doi: 10.1038/leu.2017.49.[]
   PubMed Web of Science ®Google Scholar
• Moignet A, Lamy T. Latest advances in the diagnosis and treatment of large granular lymphocytic leukemia. Am Soc Clin Oncol Educ Book. 2018;38:616–625. doi: 10.1200/EDBK_200689.
   PubMedGoogle Scholar
• Hasanov E, Fard EV, Puravath A, et al. T-cell large granular lymphocytic leukaemia in the context of rheumatoid arthritis. Lancet. 2018;392(10152):1071. doi: 10.1016/S0140-6736(18)32208-6.
   PubMed Web of Science ®Google Scholar
• Qiu ZY, Qin R, Tian GY, et al. Pathophysiologic mechanisms and management of large granular lymphocytic leukemia associated pure red cell aplasia. Onco Targets Ther. 2019;12:8229–8240. doi: 10.2147/OTT.S222378.
   PubMed Web of Science ®Google Scholar
• Gentile TC, Uner AH, Hutchison RE, et al. CD3+, CD56+ aggressive variant of large granular lymphocyte leukemia. Blood. 1994;84(7):2315–2321. doi: 10.1182/blood.V84.7.2315.2315.
   PubMed Web of Science ®Google Scholar
• Sylvia MT, Jacob SE, Basu D, et al. CD56 negative aggressive T cell large granular lymphocytic leukemia. Indian J Hematol Blood Transfus. 2016;32(Suppl 1):121–124. doi: 10.1007/s12288-015-0502-9.
   PubMedGoogle Scholar
• Liu Y, Fan L, Zhao H, et al. Metronomic regimen as an effective treatment for aggressive T-LGL leukemia with Central nervous system infiltration: clinical experience and review of literature. Oncotarget. 2017;8(19):32292–32297. doi: 10.18632/oncotarget.15762.
   PubMedGoogle Scholar
• Alekshun TJ, Tao J, Sokol L. Aggressive T-cell large granular lymphocyte leukemia: a case report and review of the literature. Am J Hematol. 2007;82(6):481–485. doi: 10.1002/ajh.20853.
   PubMed Web of Science ®Google Scholar
• Barilà G, Calabretto G, Teramo A, et al. T cell large granular lymphocyte leukemia and chronic NK lymphocytosis. Best Pract Res Clin Haematol. 2019;32(3):207–216. doi: 10.1016/j.beha.2019.06.006.
   PubMed Web of Science ®Google Scholar
• Loughran TP, Jr, Zickl L, Olson TL, et al. Immuno­suppressive therapy of LGL leukemia: prospective multicenter phase II study by the Eastern cooperative oncology group (E5998). Leukemia. 2015;29(4):886–894. doi: 10.1038/leu.2014.298.
   PubMed Web of Science ®Google Scholar
• Bareau B, Rey J, Hamidou M, et al. Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases. Haematologica. 2010;95(9):1534–1541. doi: 10.3324/haematol.2009.018481.
   PubMed Web of Science ®Google Scholar
• Loughran TP.Jr. Clonal diseases of large granular lymphocytes. Blood. 1993;82(1):1–14. doi: 10.1182/blood.V82.1.1.bloodjournal8211.
   PubMed Web of Science ®Google Scholar
• Dhodapkar MV, Li CY, Lust JA, et al. Clinical spectrum of clonal proliferations of T-large granular lymphocytes: a T-cell clonopathy of undetermined significance? Blood. 1994;84(5):1620–1627. doi: 10.1182/blood.V84.5.1620.1620.
   PubMed Web of Science ®Google Scholar
• Semenzato G, Zambello R, Starkebaum G, et al. The lymphoproliferative disease of granular lymphocytes: updated criteria for diagnosis. Blood. 1997;89(1):256–260. doi: 10.1182/blood.V89.1.256.
   PubMed Web of Science ®Google Scholar
• Neben MA, Morice WG, Tefferi A. Clinical features in T-cell vs. natural killer-cell variants of large granular lymphocyte leukemia. Eur J Haematol. 2003;71(4):263–265. doi: 10.1034/j.1600-0609.2003.00136.x.
   PubMed Web of Science ®Google Scholar
• Barilà G, Teramo A, Calabretto G, et al. Stat3 mutations impact on overall survival in large granular lymphocyte leukemia: a single-center experience of 205 patients. Leukemia. 2020;34(4):1116–1124. doi: 10.1038/s41375-019-0644-0.
   PubMed Web of Science ®Google Scholar
• Kerr CM, Clemente MJ, Chomczynski PW, et al. Subclonal STAT3 mutations solidify clonal dominance. Blood Adv. 2019;3(6):917–921. doi: 10.1182/bloodadvances.2018027862.
   PubMed Web of Science ®Google Scholar
• Rajala HL, Eldfors S, Kuusanmäki H, et al. Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia. Blood. 2013;121(22):4541–4550. doi: 10.1182/blood-2012-12-474577.
   PubMed Web of Science ®Google Scholar
• Andersson EI, Tanahashi T, Sekiguchi N, et al. High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia. Blood. 2016;128(20):2465–2468. doi: 10.1182/blood-2016-06-724856.
   PubMed Web of Science ®Google Scholar
• Jerez A, Clemente MJ, Makishima H, et al. STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia. Blood. 2012;120(15):3048–3057. doi: 10.1182/blood-2012-06-435297.
   PubMed Web of Science ®Google Scholar
• Sanikommu SR, Clemente MJ, Chomczynski P, et al. Clinical features and treatment outcomes in large granular lymphocytic leukemia (LGLL). Leuk Lymphoma. 2018;59(2):416–422. doi: 10.1080/10428194.2017.1339880.
   PubMed Web of Science ®Google Scholar
• Cheon H, Xing JC, Moosic KB, et al. Genomic landscape of TCRαβ and TCRγδ T-large granular lymphocyte leukemia. Blood. 2022;139(20):3058–3072. doi: 10.1182/blood.2021013164.
   PubMed Web of Science ®Google Scholar