BLUES - stabilizing mood and sleep with blue blocking eyewear in bipolar disorder – a randomized controlled trial study protocol

References

• Faurholt-Jepsen M, Miskowiak KW, Frost M, et al. Patient-evaluated cognitive function measured with smartphones and the association with objective cognitive function, perceived stress, quality of life and function capacity in patients with bipolar disorder. Int J Bipolar Disord. 2020;8(1):1. doi:10.1186/s40345-020-00205-1.
   PubMed Web of Science ®Google Scholar
• Kessing LV, Faurholt-Jepsen M. Mood instability – a new outcome measure in randomised trials of bipolar disorder? Eur Neuropsychopharmacol. 2022;58:39–8. doi:10.1016/j.euroneuro.2022.02.005.
   PubMed Web of Science ®Google Scholar
• Slyepchenko A, Allega OR, Leng X, et al. Association of functioning and quality of life with objective and subjective measures of sleep and biological rhythms in major depressive and bipolar disorder. Aust N Z J Psychiatry. 2019;53(7):683–696. doi:10.1177/0004867419829228.
   PubMed Web of Science ®Google Scholar
• Stanislaus S, Faurholt-Jepsen M, Vinberg M, et al. Mood instability in patients with newly diagnosed bipolar disorder, unaffected relatives, and healthy control individuals measured daily using smartphones. J Affect Disord. 2020;271:336–344. doi:10.1016/j.jad.2020.03.049.
   PubMed Web of Science ®Google Scholar
• Faurholt-Jepsen M, Busk J, Bardram JE, et al. Mood instability and activity/energy instability in patients with bipolar disorder according to day-to-day smartphone-based data – An exploratory post hoc study. J Affect Disord. 2023;334:83–91. doi:10.1016/j.jad.2023.04.139.
   PubMed Web of Science ®Google Scholar
• Sylvia LG, Chang WC, Kamali M, et al. Sleep disturbance may impact treatment outcome in bipolar disorder: a preliminary investigation in the context of a large comparative effectiveness trial. J Affect Disord. 2018;225:563–568. doi:10.1016/j.jad.2017.08.056.
   PubMed Web of Science ®Google Scholar
• Gutiérrez-Rojas L, Jurado D, Martínez-Ortega JM, et al. Poor adherence to treatment associated with a high recurrence in a bipolar disorder outpatient sample. J Affect Disord. 2010;127(1–3):77–83. doi:10.1016/j.jad.2010.05.021.
   PubMed Web of Science ®Google Scholar
• Kessing LV, Søndergård L, Kvist K, et al. Adherence to lithium in naturalistic settings: results from a nationwide pharmacoepidemiological study. Bipolar Disord. 2007;9(7):730–736. doi:10.1111/j.1399-5618.2007.00405.x.
   PubMed Web of Science ®Google Scholar
• Gottlieb JF, Benedetti F, Geoffroy PA, et al. The chronotherapeutic treatment of bipolar disorders: a systematic review and practice recommendations from the ISBD task force on chronotherapy and chronobiology. In. Bipolar Disord. 2019;21(8):741–773. doi:10.1111/bdi.12847.
   PubMed Web of Science ®Google Scholar
• Wehr TA, Turner EH, Shimada JM, et al. Treatment of rapidly cycling bipolar patient by using extended bed rest and darkness to stabilize the timing and duration of sleep. Biol Psychiatry. 1998;43(11):822–828. doi:10.1016/s0006-3223(97)00542-8.
   PubMed Web of Science ®Google Scholar
• Wirz-Justice A, Quinto C, Cajochen C, et al. A rapid-cycling bipolar patient treated with long nights, bedrest, and light. Biol Psychiatry. 1999;45(8):1075–1077. doi:10.1016/S0006-3223(98)00289-3.
   PubMed Web of Science ®Google Scholar
• Barbini B, Benedetti F, Colombo C, et al. Dark therapy for mania: a pilot study. Bipolar Disord. 2005;7(1):98–101. doi:10.1111/j.1399-5618.2004.00166.x.
   PubMed Web of Science ®Google Scholar
• Henriksen TE, Skrede S, Fasmer OB, et al. Blocking blue light during mania - markedly increased regularity of sleep and rapid improvement of symptoms: a case report. Bipolar Disord. 2014;16(8):894–898. doi:10.1111/bdi.12265.
   PubMed Web of Science ®Google Scholar
• Hester L, Dang D, Barker CJ, et al. Evening wear of blue-blocking glasses for sleep and mood disorders: a systematic review. Chronobiol Int. 2021;38(10):1375–1383. doi:10.1080/07420528.2021.1930029.
   PubMed Web of Science ®Google Scholar
• Henriksen TE, Skrede S, Fasmer OB, et al. Blue-blocking glasses as additive treatment for mania: a randomized placebo-controlled trial. Bipolar Disord. 2016;18(3):221–232. doi:10.1111/bdi.12390.
   PubMed Web of Science ®Google Scholar
• Henriksen TEG, Grønli J, Assmus J, et al. Blue-blocking glasses as additive treatment for mania: effects on actigraphy-derived sleep parameters. J Sleep Res. 2020;29(5):e12984. doi:10.1111/jsr.12984.
   PubMed Web of Science ®Google Scholar
• Esaki Y, Takeuchi I, Tsuboi S, et al. A double-blind, randomized, placebo-controlled trial of adjunctive blue-blocking glasses for the treatment of sleep and circadian rhythm in patients with bipolar disorder. Bipolar Disord. 2020;22(7):739–748. doi:10.1111/bdi.12912.
   PubMed Web of Science ®Google Scholar
• Hattar S, Kumar M, Park A, et al. Central projections of melanopsin-expressing retinal ganglion cells in the mouse. J Comp Neurol. 2006;497(3):326–349. doi:10.1002/cne.20970.
   PubMed Web of Science ®Google Scholar
• Legates TA, Altimus CM, Wang H, et al. Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 2012;491(7425):594–598. doi:10.1038/nature11673.
   PubMed Web of Science ®Google Scholar
• Legates TA, Fernandez DC, Hattar S. Light as a Central modulator of circadian rhythms, sleep and affect. Nat Rev Neurosci. 2014;15(7):443–454. doi:10.1038/nrn3743.
   PubMed Web of Science ®Google Scholar
• Vandewalle G, Maquet P, Dijk D-J. Light as a modulator of cognitive brain function. Trends Cogn Sci. 2009;13(10):429–438. doi:10.1016/j.tics.2009.07.004.
   PubMed Web of Science ®Google Scholar
• Kawasaki A, Wisniewski S, Healey B, et al. Impact of long-term daylight deprivation on retinal light sensitivity, circadian rhythms and sleep during the antarctic winter. Sci Rep. 2018;8(1):1–12. doi:10.1038/s41598-018-33450-7.
   PubMedGoogle Scholar
• Lax P, Ortuño-Lizarán I, Maneu V, et al. Photosensitive melanopsin-containing retinal ganglion cells in health and disease: implications for circadian rhythms. Int J Mol Sci. 2019;20(13):3164. doi:10.3390/ijms20133164.
   PubMed Web of Science ®Google Scholar
• Münch M, Kourti P, Brouzas D, et al. Variation in the pupil light reflex between winter and summer seasons. Acta Ophthalmol. 2016;94(3):e244–e246. doi:10.1111/aos.12966.
   PubMed Web of Science ®Google Scholar
• Münch M, Léon L, Crippa SV, et al. Circadian and wake-dependent effects on the pupil light reflex in response to narrow-bandwidth light pulses. Invest Ophthalmol Vis Sci. 2012;53(8):4546–4555. doi:10.1167/iovs.12-9494.
   PubMed Web of Science ®Google Scholar
• Ritter P, Wieland F, Skene DJ, et al. Melatonin suppression by melanopsin-weighted light in patients with bipolar disorder compared to healthy controls. J Psychiatry Neurosci. 2020;45(2):79–87. doi:10.1503/jpn.190005.
   PubMed Web of Science ®Google Scholar
• Van Der Meijden WP, Van Someren JL, Te Lindert BHW, et al. Individual differences in sleep timing relate to melanopsin-based phototransduction in healthy adolescents and young adults. Sleep. 2016;39(6):1305–1310. doi:10.5665/sleep.5858.
   PubMed Web of Science ®Google Scholar
• Berman G, Muttuvelu D, Berman D, et al. Decreased retinal sensitivity in depressive disorder: a controlled study. Acta Psychiatr Scand. 2018;137(3):231–240. doi:10.1111/acps.12851.
   PubMed Web of Science ®Google Scholar
• Laurenzo SA, Kardon R, Ledolter J, et al. Pupillary response abnormalities in depressive disorders. Psychiatry Res. 2016;246:492–499. doi:10.1016/j.psychres.2016.10.039.
   PubMed Web of Science ®Google Scholar
• Madsen HØ, Ba-Ali S, Heegaard S, et al. Melanopsin-mediated pupillary responses in bipolar disorder—a cross-sectional pupillometric investigation. Int J Bipolar Disord. 2021;9(1):1–10. doi:10.1186/s40345-020-00211-3.
   PubMed Web of Science ®Google Scholar
• McGlashan EM, Coleman MY, Vidafar P, et al. Decreased sensitivity of the circadian system to light in current, but not remitted depression. J Affect Disord. 2019;256:386–392. doi:10.1016/j.jad.2019.05.076.
   PubMed Web of Science ®Google Scholar
• Roecklein KA, Rohan KJ, Duncan WC, et al. A missense variant (P10L) of the melanopsin (OPN4) gene in seasonal affective disorder. J Affect Disord. 2009;114(1-3):279–285. doi:10.1016/j.jad.2008.08.005.
   PubMed Web of Science ®Google Scholar
• Ritter P, Soltmann B, Sauer C, et al. Supersensitivity of patients With bipolar I disorder to light-Induced phase delay by narrow bandwidth blue light. Biol Psychiatry Glob Open Sci. 2022;2(1):28–35. doi:10.1016/j.bpsgos.2021.06.004.
   PubMedGoogle Scholar
• Kessing LV, Kyster NB, Bondo-Kozuch P, et al. Effect of specialised versus generalised outpatient treatment for bipolar disorder: the CAG bipolar trial - study protocol for a randomised controlled trial. BMJ Open. 2021;11(10):e048821. doi:10.1136/bmjopen-2021-048821.
   PubMed Web of Science ®Google Scholar
• Wing JK, Babor T, Brugha T, et al. SCAN. Arch Gen Psychiatry. 1990;47(6):589–593. doi:10.1001/archpsyc.1990.01810180089012.
   PubMed Web of Science ®Google Scholar
• Young RC, Biggs JT, Ziegler VE, et al. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 1978;133(5):429–435. doi:10.1192/bjp.133.5.429.
   PubMed Web of Science ®Google Scholar
• Hamilton M. A rating scale FOR depression. J Neurol Neurosurg Psychiatry. 1960;23(1):56–62. doi:10.1136/jnnp.23.1.56.
   PubMed Web of Science ®Google Scholar
• Rosa AR, Sánchez-Moreno J, Martínez-Aran A, et al. Validity and reliability of the functioning assessment short test (FAST) in bipolar disorder. Clin Pract Epidemiol Ment Health. 2007;3(1):5. doi:10.1186/1745-0179-3-5.
   PubMedGoogle Scholar
• Krane-Gartiser K, Asheim A, Fasmer OB, et al. Actigraphy as an objective intra-individual marker of activity patterns in acute-phase bipolar disorder: a case series. Int J Bipolar Disord. 2018;6(1):8. doi:10.1186/s40345-017-0115-3.
   PubMedGoogle Scholar
• Murray G, Gottlieb J, Hidalgo MP, et al. Measuring circadian function in bipolar disorders: empirical and conceptual review of physiological, actigraphic, and self-report approaches. Bipolar Disord. 2020;22(7):693–710. doi:10.1111/bdi.12963.
   PubMed Web of Science ®Google Scholar
• Lyall LM, Wyse CA, Graham N, et al. Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK biobank. Lancet Psychiatry. 2018;5(6):507–514. doi:10.1016/S2215-0366(18)30139-1.
   PubMed Web of Science ®Google Scholar