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Annals of Medicine Volume 55, 2023 - Issue 2
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Public Health

Transforming malaria prevention and control: the prospects and challenges of gene drive technology for mosquito management

Yusuf Amuda Tajudeena Department of Epidemiology and Medical Statistics, Faculty of Public Health, College of Medicine, University of Ibadan, Ibadan, Nigeria;b Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, NigeriaORCID Iconhttps://orcid.org/0000-0001-7441-1468View further author information
ORCID Icon,
Habeebullah Jayeola Oladipob Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria;c Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, NigeriaORCID Iconhttps://orcid.org/0000-0002-0146-1349View further author information
ORCID Icon,
Iyiola Olatunji Oladunjoyeb Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, NigeriaORCID Iconhttps://orcid.org/0000-0002-6760-5448View further author information
ORCID Icon,
Muhammad Kamaldeen Oladipoc Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, NigeriaView further author information
,
Hameedat Damilola Shittuc Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, NigeriaView further author information
,
Imam-Fulani Abdulmumeend Faculty of health science, Department of Public health, Alhikmah University Ilorin, Ilorin, NigeriaView further author information
,
Abdullateef Opeyemi Afolabie Faculty of Biomedical Sciences, Department of Microbiology and Immunology, Kampala International University, Bushenyi, UgandaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6440-1805View further author information
ORCID Icon &
Mona Said El-Sherbinif Department of Medical Parasitology, Faculty of Medicine, Cairo University, Cairo, EgyptView further author information
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Article: 2302504 | Received 25 Oct 2023, Accepted 02 Jan 2024, Published online: 17 Jan 2024

References

  • Oladipo HJ, Tajudeen YA, Oladunjoye IO, et al. Increasing challenges of malaria control in Sub-saharan africa: priorities for public health research and policymakers. Ann Med Surg. 2022;81:1. doi:10.1016/j.amsu.2022.104366.
  • World Health Organization (WHO). World malaria report 2022. https://who.int/publications-details-redirect/9789240064898
  • World Health Organization (WHO). Fact sheet about malaria. https://www.who.int/news-room/fact-sheets/detail/malaria
  • Battle KE, Baird JK. The global burden of Plasmodium vivax malaria is obscure and insidious. PLoS Med. 18(10):e1003799. doi:10.1371/journal.pmed.1003799.
  • Wise IJ, Borry P. An ethical overview of the CRISPR-based elimination of Anopheles gambiae to combat malaria. J Bioeth Inq. 2022;19(3):371–5. doi:10.1007/s11673022-10172-0.
  • Nolan T. Control of malaria-transmitting mosquitoes using gene drives. Phil Trans R Soc. B. 2019;36:2019080.
  • Hammond AM, Kyrou K, Bruttini M, et al. The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito. PLoS Genet. 2017;13(10):e1007039. doi:10.1371/journal.pgen.1007039.
  • National Academies of Sciences, Engineering, and Medicine. 2016. Gene drives on the horizon: advancing science, navigating uncertainty, and aligning research with public values. Washington, DC: the National Academies Press. doi:10.17226/23405.
  • Tajudeen YA, Oladunjoye IO, Atta HI, et al. CRISPR-Cas systems: a potential tool to reduce the global burden of antimicrobial resistance. BE. 2021;4(2):e273. https://office.scicell.org/index.php/BE/article/view/273 doi:10.36547/be.273.
  • World Health Organization. Guidance framework for testing of genetically modified mosquitoes. 2nd ed. Global Malaria Programme; 2021.
  • Kyrou K, Hammond AM, Galizi R, et al. A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes. Nat Biotechnol. 2018;36(11):1062–1066. doi:10.1038/nbt.4245.
  • Hammond A, Galizi R, Kyrou K, et al. A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae. Nat Biotechnol. 2016;34(1):78–83. doi:10.1038/nbt.3439.
  • Bier E. Gene drives gaining speed. Nat Rev Genet. 2022;23(1):5–22. doi:10.1038/s41576-021-00386-0.
  • Nolan T. Control of malaria-transmitting mosquitoes using gene drives. Philos Trans R Soc Lond B Biol Sci. 2021;376(1818):20190803. doi:10.1098/rstb.2019.0803.
  • Hammond A, Pollegioni P, Persampieri T, et al. Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field. Nat Commun. 2021;12(1):4589. doi:10.1038/s41467021-24790-6.
  • North AR, Burt A, Godfray HCJ. Modelling the potential of genetic control of malaria mosquitoes at national scale. BMC Biol. 2019;17(1):26. doi:10.1186/s12915-019-0645-5.
  • Pham TB, Phong CH, Bennett JB, et al. Experimental population modification of the malaria vector mosquito, Anopheles stephensi. PLoS Genet. 2019;15(12):e1008440. doi:10.1371/journal.pgen.1008440.
  • Iyer HS, DeVille NV, Stoddard O, et al. Sustaining planetary health through systems thinking: public health’s critical role. SSM Popul Health. 2021; Sep 115:100844. doi:10.1016/j.ssmph.2021.100844.

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