Toll-like receptor 4 and atherogenesis

References

• Medzhitov R, Janeway C. Innate immunity. N Engl J Med 2000; 343: 338–44.
   PubMed Web of Science ®Google Scholar
• Hansson GK, Libby P, Schoenbeck U, Yan ZQ. Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 2002; 91: 281–91.
   PubMed Web of Science ®Google Scholar
• Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 1999; 274: 10689–92.
   PubMed Web of Science ®Google Scholar
• Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002; 168: 554–61.
   PubMed Web of Science ®Google Scholar
• Beg AA. Endogenous ligands of Toll-like receptors: implica-tions for regulating inflammatory and immune responses. Trends Immunol 2002; 23: 509–12.
   PubMed Web of Science ®Google Scholar
• Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2: 675–80.
   PubMed Web of Science ®Google Scholar
• Martin MU, Wesche H. Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family. Biochim Biophys Acta 2002; 1592: 265–80.
   PubMed Web of Science ®Google Scholar
• Kiechl S, Lorenz E, Reindl M, Wiedermann CJ, Oberhol-lenzer F, Bonora E, et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 2002; 347: 185–92.
   PubMed Web of Science ®Google Scholar
• Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000; 1: 398–401.
   PubMed Web of Science ®Google Scholar
• Sasu S, LaVerda D, Qureshi N, Golenbock DT, Beasley D. Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via Toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation. Circ Res 2001; 89: 244–50.
   PubMed Web of Science ®Google Scholar
• Ohashi K, Burkart V, Floh S, Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex. J Immunol 2000; 164: 558–61.
   PubMed Web of Science ®Google Scholar
• Xu Q. Role of heat shock proteins in atherosclerosis. Arteriosder Thromb Vasc Biol 2002; 22: 1547–59.
   PubMed Web of Science ®Google Scholar
• Dybdahl B, Wahba A, Lien E, Flo TH, Waage A, Qureshi N, et al. Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation 2002; 105: 685–90.
   PubMed Web of Science ®Google Scholar
• Faure E, Thomas L, Xu H, Medvedev A, Equils O, Arditi M. Bacterial lipopolysaccharide and INF-y induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-KB activation. J Immunol 2001; 166: 2018–24.
   PubMed Web of Science ®Google Scholar
• Xu XH, Shah PK, Faure E, Equils O, Thomas L, Fishbein MC, et al. Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation 2001; 104: 3103–8.
   PubMed Web of Science ®Google Scholar
• Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2 and inhibits phagocytosis of apoptotic cells. J Biol Chem 2002: (in press).
   Google Scholar
• Smirnova I, Hamblin MT, McBride C, Beuder B, Di Rienzo A. Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans. Genetics 2001; 158: 1657–64.
   PubMed Web of Science ®Google Scholar
• Arbour NC, Lorenz E, Schutte BC, Zabner J, Kline JN, Jones M, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000; 25: 187–91.
   PubMed Web of Science ®Google Scholar
• Lorenz E, Frees KL, Schwartz DA. Determination of the TLR4 genotype using allele-specific PCR. Biotechniques 2001; 31: 22–4.
   PubMed Web of Science ®Google Scholar
• Ridker PM. On evolutionary biology, inflammation, infection, and the causes of atherosclerosis. Circulation 2002; 105: 2–4.
   PubMed Web of Science ®Google Scholar
• Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ. Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 2002; 105: 1158–61.
   PubMed Web of Science ®Google Scholar
• Vink A, Schoneveld AH, van der Meer JJ, van Middelaar BJ, Sluijter JP, Smeets MB, et al. In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions. Circulation 2002; 106: 1985–90.
   PubMed Web of Science ®Google Scholar
• Liao F, Andalibi A, deBeer FC, Fogelman AM, Lusis AJ. Genetic control of inflammatory gene induction and NF-kappa B-like transcription factor activation in response to an atherogenic diet in mice. J Clin Invest 1993; 91: 2572–9.
   PubMed Web of Science ®Google Scholar
• Shi W, Haberland ME, Pen ML, Shih DM, Lusis AJ. Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice. Circulation 2000; 102: 75–81.
   PubMed Web of Science ®Google Scholar
• Kithel DG, Zhu B, Witte DP, Hui DY. Distinction in genetic determinants for injury-induced neointimal hyperplasia and diet-induced atherosclerosis in inbred mice. Arteriosder Thromb Vasc Biol 2002; 22: 955–60.
   Google Scholar
• Breslow JL. Genetic differences in endothelial cells may determine atherosclerosis susceptibility. Circulation 2000; 102: 5–6.
   Google Scholar
• Wright SD, Burton C, Hernandez M, Hassing H, Montenegro J, Mundt S, et al. Infectious agents are not necessary for murine atherogenesis. J Exp Med 2000; 191: 1437–42.
   PubMed Web of Science ®Google Scholar
• Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336: 973–9.
   PubMed Web of Science ®Google Scholar
• Kiechl S, Egger G, Mayr M, Wiedermann CJ, Bonora E, Oberhollenzer F, et al. Chronic infections and the risk of carotid atherosclerosis. Prospective results from a large population study. Circulation 2001; 103: 1064–70.
   PubMed Web of Science ®Google Scholar
• Wiedermann CI, Kiechl S, Dunzendorfer S, Schratzberger P, Egger G, Oberhollenzer F, et al. Association of endotox-emia with carotid atherosclerosis and cardiovascular disease. Prospective results from the Bruneck Study. J Am Coll Cardiol 1999; 34: 1975–81.
   PubMed Web of Science ®Google Scholar
• Agnese DM, Calvano JE, Hahm SJ, Coyle SM, Corbett SA, Calvano SE, et al. Human Toll-Like Receptor 4 Mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections. J Infect Dis 2002; 186: 1522–5.
   PubMed Web of Science ®Google Scholar
• Ozinsky A, Underhill DM, Fontenot JD, Haj jar AM, Smith KD, Wilson CB, et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA 2000; 97: 13766–71.
   PubMed Web of Science ®Google Scholar
• Guillot L, Balloy V, McCormack FX, Golenbock DT, Chignard M, Si-Tahar M. Cutting edge: the immunostimu-latory activity of the lung surfactant protein-A involves Toll-like receptor 4. J Immunol 2002; 168: 5989–92.
   PubMed Web of Science ®Google Scholar
• Lorenz E, Mira JP, Frees ICL, Schwartz DA. Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 2002; 162: 1028–32.
   PubMed Web of Science ®Google Scholar
• Lorenz E, Hallman M, Marttila R, Haataja R, Schwartz DA. Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population. Pediatr Res 2002; 52: 373–6.
   PubMed Web of Science ®Google Scholar
• Roy S, Knox K, Segal S, Griffiths D, Moore CE, Welsh KI, et al. MBL genotype and risk of invasive pneumococcal disease: a case-control study. Lancet 2002; 359: 1569–73.
   PubMed Web of Science ®Google Scholar
• Bach JF. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002; 347: 911–20.
   PubMed Web of Science ®Google Scholar
• Raby BA, Klimecici WT, Laprise C, Renaud Y, Faith J, Letnire M, et al. Polymorphisms in Toll-Like Receptor 4 are not associated with asthma or atopy-related phenotypes. Am J Respir Crit Care Med 2002; 166: 1449–56.
   PubMed Web of Science ®Google Scholar
• Reindl M, Lutterotti A, Ingram J, et al. Mutations in the gene for Toll-like receptor 4 and multiple sclerosis. Tissue Antigens 2003; 61: 85–8.
   PubMedGoogle Scholar
• Andreotti F, Porto I, Crea F, Maseri A. Inflammatory gene polymorphisms and ischaemic heart disease: review of population association studies. Heart 2002; 87: 107–12.
   PubMed Web of Science ®Google Scholar