223
Views
24
CrossRef citations to date
0
Altmetric
Research Article

Molecular genetics in the analysis of suicide

, , &
Pages 191-196 | Published online: 08 Jul 2009

References

  • Jamison KR. Night Falls Fast. New York, NY: Alfred Knopf Publishers, 1999.
  • Mäkinen IH, Wasserman D. Suicide prevention and cultural resistance: stability in suicide ranking of European countries, 1970-88. Ital J Suicidology 1997; 7: 73–85.
  • American Association of Suicidology. U S A Suicide: 1998 Official Final Data. Available at: http://www.suicidology. org/index.cfm
  • Phillips MR, Liu H, Zhang Y. Suicide and social change in China. Cult Med Psychiatry 1999; 23: 25–50.
  • Yoshioka N. Epidemiological study of suicide in Japan: is it possible to reduce committing suicide? Nippon Hoigaku Zasshi 1998; 52: 286–93.
  • Smith S. Seasonality of suicide. Br J Psychiatry 2001; 178: 183–4.
  • Hilton SC, Fellingham GW, Lyon JL. Suicide rates and religious commitment in young adult males in Utah. Am ] Epidemiol 2002; 155: 413–9.
  • Kellermann AL, Rivara FP, Somes G, Reay DT, Francisco J, Banton JG, et al. Suicide in the home in relation to gun ownership. N Engl ] Med 1992; 327: 467–72.
  • Group for the Advancement of Psychiatry. Adolescent Suicide (GAP Report 140). Washington, DC: American Psychiatric Press; 1996.
  • Goldman S, Beardslee WR. Suicide in children and adolescents. In: Jacobs D, ed. Harvard Medical School. Guide to Assessment and Intervention in Suicide. San Francisco, Calif: Jossey-Bass; 1998: 417–42.
  • Minois G. History of Suicide, Voluntary Death, in Western Culture. Baltimore, Md: Johns Hopkins University Press; 1999.
  • Murphy GE. Why women are less likely than men to commit suicide. Compr Psychiatry 1998; 39: 165–75.
  • Jensen G, Jensen BF, Arensman E, Bille-Brahe U, Crepet P, De Leo D, et al. Attempted suicide and major public holidays in Europe: Findings from the WHO multicenter study on parasuicide. Acta Psychiatr Scand 1999; 99: 412–8.
  • Hakko H, Rasanen P, Tiihonen J. Seasonal variation in suicide occurrence in Finland. Acta Psychiatr Scand 1999; 99: 308–10.
  • Massing W, Angermeyer MC. The monthly and weekly distribution of suicide. Soc Set Med 1985; 21: 433–41.
  • Linkowski P, Martin F, De Maertelaer V. Effect of some clinical factors on violent and non-violent suicides in Belgium. J Affect Disord 1992; 3: 161–6.
  • Robins E, Schmidt EH, O'Neal P. Some interrelations of social factors and clinical diagnosis in attempted suicide: a study of 109 patients. Am J Psychiatry 1957; 114: 221–31.
  • Papadimitriou GN, Linkowski P, Souery D, Mendlewicz J. Genetic factors and suicidal behaviour. In Papadimitriou GN. and Mendlewicz ].: Genetics of Mental Disorders Part II: Clinical Issues. Bailliere's Clinical Psychiatry, International Practice and Research. London, UK; Bailliere Tindall, Vol. 2, No 1, February 1996.
  • Turecki G. Suicidal behavior: is there a genetic predisposition? Bipolar Disord 2001; 3: 335–49.
  • Brent DA, Oquendo M, Birmaher B, Greenhill L, Kolko D, Stanley B, et al. Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Arch Gen Psychiatry 2002; 59: 801–7.
  • Roy A. Family history of suicide. Arch Gen Psychiatry 1983; 40: 971–4.
  • Miterrauer B. A contribution to the discussion of the role of the genetic factor in suicide, based on five studies in an epidemiologically defined area. Compr Psychiatry 1990; 31: 557–65.
  • Linkowski P, De Maertelaer V, Mendlewicz J. Suicidal behavior in major depressive illness. Acta Psychiatr Scand 1985; 72: 233–8.
  • Roy A, Segal N. Suicidal behavior in twins: a replication. J Affect Disord 2001; 66: 71–4.
  • Statham D, Heath A, Madden P, Bucholz ICK, Bierut L, Dinwiddie SH, et al. Suicidal behavior: an epidemiological and genetic study. Psychol Med 1998; 28: 839–55.
  • Fu Q, Heath AC, Bucholz KK, Nelson EC, Glowinski AL, Goldberg J, et al. A twin study of genetic and environmental influences on suicidality in men. Psychol Med 2002; 32: 11–24.
  • Schulsinger R, Kety S, Rosenthal D, Wender P. A family study of suicide. In: Schou M, Stromgren LE, eds. Origins, prevention and treatment of affective disorders.. New York: Academic Press Inc, 1979: 277–87.
  • Wender P, Kety S, Rosenthal D, Schulsinger F, Ortmann J, Lunde IL. Psychiatric disorders in the biological and adoptive families of adopted individuals with affective disorder. Arch Gen Psychiatry 1986; 43: 923–6.
  • Angst J, Angst F, Stassen HH. Suicide Risk in patients with major depressive disorder. J Clin Psychiatry Suppl. Discussion 1999; 60: 57–62,75-76, 113-6.
  • Barradough BM, Pallis DJ. Depression followed by suicide: a comparison of depressed suicides with living depressives. Psychol Med 1975; 5: 55–61.
  • Blair-West GW, Cantor CH, Mellsop GW, Eyeson-Annan ML. Lifetime suicide risk in major depression: sex and age determinants. J Affect Disord 1999; 55: 171–8.
  • Mann JJ, Waternaux C, Haas GL, Malone KM. Toward a clinical model of suicidal behavior in psychiatric patients. Am J Psychiatry 1999; 156: 181–9.
  • Asberg M, Traslcman L, Thoren P. 5-HIAA in the cere-brospinal fluid. A biochemical suicide predictor. Arch Gen Psychiatry 1976; 33: 1193–7.
  • Brown GL, Goodwin FK. Cerebrospinal fluid correlates of suicide attempts and aggression. Ann NY Acad Sci 1986; 487: 175–88.
  • Mann JJ. The Neurobiology of suicide. Nat Med 1998; 4: 25–30.
  • Mann JJ, Henteleff RA, Lagattuta TF, Perper JA, Li S, Arango V. Lower 3H-paroxetine binding in cerebral cortex of suicide victims is partly due to fewer high affinity, non-transporter sites. J Neural Transm 1996; 103: 1337–50.
  • Arango V, Underwood MD, Gubbi AV, Mann JJ. Localized alterations in pre-et postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Res 1995; 688: 121–33.
  • Nordstrom P, Samuelsson M, Asberg M, Traslcman-Bendz L, Aberg-Wistedt A, Nordin C, et al. CSF 5-HIAA predicts suicide risk after attempted suicide. Suicide Life Threat Behav 1988; 24: 1–9.
  • Roy A, Agren H, Pickar D, Linnoila M, Doran AR, Cutler NR, et al. Reduced CSF concentrations of homovanillic and homovanillic acid to 5-Hydroxyindoleacetic acid ratios in depressed patients: relationship to suicidal behavior and dexamethasone nonsuppression. Am J Psychiatry 1986; 143: 1539–45.
  • Cooper SJ, Kelly CB, King DJ. 5-Hydroxyindoleacetic acid in cerebrospinal fluid and prediction of suicidal behavior in schizophrenia. Lancet 1992; 340: 940–1.
  • Nielsen D, Dean M, Goldman D. Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism. Am J Hum Genet 1992; 51: 1366–71.
  • Nielsen D, Goldman D, Virklcunen M, Tokola R, Rawlings R, Linnoila M. Suicidality and 5-Hydroxyindoleacetic acid concentration association with a tryptophan hydroxylase polymorphism. Arch Gen Psychiatry 1994; 51: 34–8.
  • Nielsen D, Virkkunen M, Lappalainen J, Eggert M, Brown GL, Long JC, et al. A tryptophan hydroxylase gene marker for suicidality and alcoholism. Arch Gen Psychiatry 1998; 55: 593–602.
  • Abbar M, Courtet P, Amadeo S, Caer Y, Mallet J, Baldy-Moulinier M, et al. Suicidal behaviors and the tryptophan hydroxylase gene. Arch Gen Psychiatry 1995; 52: 846–9.
  • Mann JJ, Malone KM, Nielsen DA, Goldman D, Erdos J, Gelernter J. Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients. Am J Psychiatry 1997; 154: 1451–3.
  • Bellivier F, Leboyer M, Courtet P, Buresi C, Beaufils B, Samolyk D, et al. Association between the tryptophan hydroxylase gene and manic-depressive illness. Arch Gen Psychiatry 1998; 55: 33–7.
  • Souery D, Van Gestel S, Massat I, Blairy S, Adolfsson R, Blackwood D, et al. Tryptophan hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders: a multicenter association study. Biol Psychiatry 2001; 49: 405–9.
  • Turecici G, Zhu J, Tzenova J, Lesage A, Seguin M, Tousignant M, et al. TPH and suicidal behavior: a study in suicide completers. Mol Psychiatry 2001; 6: 98–102.
  • Fitch D, Lesage A, Seguin M, Trousignant M, Bankelfat C, Rouleau GA, et al. Suicide and the serotonin transporter gene. Mol Psychiatry 2001; 6: 127–8.
  • Bellivier F, Laplanche J, Leboyer M, Feingold J, Bottos C, Allilaire JF, et al. Serotonin transporter gene associated and manic depressive illness: an association study. Biol Psychiatry 1997; 41: 750–2.
  • Bellivier F, Szoke A, Henry C, Lacoste J, Bottos C, Nosten-Bertrand M, et al. Possible association between serotonin transporter gene polymorphism and violent suicidal behavior in mood disorders. Biol Psychiatry 2000; 48: 319–22.
  • Russ M, Lachman H, Kashdan T, Saito T, Bajmakovic-Kacila S. Analysis of catechol-o-methyltransferase and 5-hydroxytryptamine transporter polymorphisms in patients at risk for suicide. Psychiatr Res 2000; 93: 73–8.
  • Du L, Faludi G, Palkovits M, Demeter E, Bakish D, Lapierre YD, et al. Frequency of long allele in serotonin transporter gene is increased in depressed suicide victims. Biol Psychiatry 1999; 46: 196–201.
  • Bondy B, Erfurth A, de Jonge S, Kruger M, Meyer H. Possible association of the short allele of the serotonin transporter promoter gene polymorphism (5-HTTLPR) with violent suicide. Mol Psychiatry 2000; 5: 193–5.
  • Mann JJ, Huang YY, Underwood M, Kassir SA, Oppen-heim S, Kelly TM, et al. A serotonin transporter promoter gene polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide. Arch Gen Psychiatry 2000; 57: 729–38.
  • Brunner HG, Nelen MR, van Zandvoort P. X-linked borderline mental retardation with prominent behavioral disturbance: phenotype, genetic localization, and evidence for disturbed monoamine metabolism. Am J Hum Genet 1993; 52: 1032–9.
  • Buchsbaum M, Coursey R, Murphy D. The biochemical high-risk paradigm: behavioural and familial correlates of low platelet monoamine oxidase activity. Science 1976; 191: 339–41.
  • Ho LW, Furlong RA, Rubinsztein JS, Walsh C, Paykel ES, Rubinsztein DC. Genetic associations with clinical charac-teristics in bipolar affective disorder and recurrent unipolar depressive disorder. Am J Med Genet 2000; 96: 36–42.
  • Ono H, Shirakawa O, Nishiguchi N, Nishimura A, Nushida H, Ueno Y, et al. No evidence of an association between a functional monoamine oxidase a gene polymorph-ism and completed suicides. Am J Med Genet 2002; 114: 340–2.
  • Warren JT, Peacock ML, Rodriguez LC, Fink JK. An M sp I polymorphism in the human serotonin receptor gene (HTR2A): detection by DGGE and RFLP analysis. Hum Mol Genet 1993; 3: 338.
  • Zhang HY, Ishigalci T, Tani K, Chen K, Shih JC, Miyasato K, et al. Serotonin2A receptor gene polymorphism in mood disorders. Biol Psychiatry 1997; 41: 768–73.
  • Du L, Balcish D, Lapierre YD, Ravindran AV, Hrdina PD. Association of polymorphism of serotonin 2A receptor gene with suicidal ideation in major depressive disorder. Am J Med Genet (Neuropsychiatr Genet) 2000; 96: 56–60.
  • Oswald P, Souery D, Massat I, Del-Favero J, Linotte S, Papadimitriou G, et al. Lack of association between the 5HT2A Receptor Polymorphism and Unipolar Affective Disorder in a Multicentric European Study. European Neuropsychopharmacology (in press).
  • Bondy B, Kuznik J, Baghai T. Lack of association of serotonin-2A receptor gene polymorphism (T102C) with suicidal ideation and suicide. Am J Med Genet (Neuropsy-chiatr Genet) 2000; 96: 831–5.
  • Turecki G, Brière R, Dewar K, Antonetti T, Lesage AD, Seguin M, et al. Prediction of level of serotonin 2A receptor binding by serotonin 2A receptor genetic variation in post-mortem brain samples from subjects who did or did not commit suicide. Am J Psychiatry 1999; 156: 1456–8.
  • Niswender CM, Herrick-Davis K, Dilley GE, Meltzer HY, Overholser JC, Stocicmeier CA, et al. RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsy-chopharmacology 2001; 24: 478–91.
  • Gurevich I, Tamir H, Arango V, Dwork AJ, Mann JJ, Sdunauss C. Altered Editing of Serotonin 2C Receptor Pre-inRNA in the Prefrontal Cortex of Depressed Suicide Victims. Neuron 2002; 34: 349–56.
  • Evans J, Reeves B, Platt H, Leibenau A, Goldman D, Jefferson K, et al. Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH). Psychol Med 2000; 30: 1327–34.
  • Persson ML, Wasserman D, Geijer T, Jonsson EG, Terenius L. Tyrosine hydroxylase allelic distribution in suicide attemp-ters. Psychiatry Res 1997; 72: 73–80.
  • Souery D, Rivelli SK, Mendlewicz J. Molecular genetic and family studies in affective disorders: state of the art. J Affect Disord 2001; 62: 45–55.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.