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Blood Pressure Volume 31, 2022 - Issue 1
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Editorial

Thirty years with LIFE—a randomized clinical trial with more than 200 published articles on clinical aspects of left ventricular hypertrophy

Sverre E. Kjeldsena Departments of Cardiology and Nephrology, Ullevaal Hospital, University of Oslo, Oslo, NorwayCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2389-0272
ORCID Icon,
Brent M. Eganb American Medical Association, University of South Carolina, Greenville, SC, USA
,
Krzysztof Narkiewiczc Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland
,
Reinhold Kreutzd Charité, Institute of Clinical Pharmacology and Toxicology, Medical University of Berlin, Berlin, GermanyORCID Iconhttps://orcid.org/0000-0002-4818-211X
ORCID Icon,
Michel Burniere Service of Nephrology and Hypertension, University of Lausanne, Lausanne, SwitzerlandORCID Iconhttps://orcid.org/0000-0003-1283-8487
ORCID Icon &
Suzanne Oparilf Department of Medicine, Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, AL, USA
Pages 125-128 | Received 23 May 2022, Accepted 25 May 2022, Published online: 08 Jun 2022

References

  • Dahlöf B, Devereux RB, Kjeldsen SE, LIFE Study Group, et al. Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002;359(9311):125–1003.
  • Okin PM, Hille D, Kjeldsen SE, et al. Impact of lower achieved blood pressure on outcomes in hypertensive patients. J Hypertens. 2012;30(4):802–810.
  • Whelton PK, Carey RM, Aronow WS, et al. 2017ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American college of cardiology/American heart association task force on clinical practice guidelines. J Am Coll Cardiol. 2018;15(71):e127–e248.
  • Zhang W, Zhang S, Deng Y, STEP Study Group, et al. Trial of intensive blood-pressure control in older patients with hypertension. N Engl J Med. 2021;385(14):1268–1279.
  • Bang C, Greve AM, Køber L, et al. Incident atrial fibrillation and heart failure in treated hypertensive patients with left ventricular hypertrophy. The LIFE study. Explor Med. 2022;3:139–148.
  • Bang C, Li Z, Stokke IM, et al. Incident left bundle branch block predicts cardiovascular events and death in hypertensive patients with left ventricular hypertrophy. The LIFE study. Explor Med. 2022;3:149–159.
  • Zacks ES, Stokke IM, Wachtell K, et al. Time-varying serum uric acid predicts new-onset atrial fibrillation in treated hypertensive patients. The LIFE study. Explor Med. 2022;3:128–138.
  • Hille DA, Kjeldsen SE, Julius S, et al. A point system table to estimate the risk of cardiovascular events in patients with hypertension and left ventricular hypertrophy. The LIFE study. OBM Geriatr. 2022;6(1):1–18.
  • Lilja-Cyron A, Bang CN, Gerdts E, et al. Aortic root dilatation in hypertensive patients with left ventricular hypertrophy - application of a new multivariate predictive model. The LIFE study. Rev Cardiovasc Med. 2022;23(3):095.
  • Gerholt L, Bang CN, Gerdts E, et al. Left atrial systolic force in hypertensive patients with left ventricular hypertrophy – a predictor of incident atrial fibrillation. The LIFE study. OBM Geriatr. 2022;6(1):1–15.
  • Chinali M, Aurigemma GP, Gerdts E, et al. Development of systolic dysfunction unrelated to myocardial infarction in treated hypertensive patients with left ventricular hypertrophy. The LIFE study. Explor Med. 2022;3:160–172.

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