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Blood Pressure Volume 32, 2023 - Issue 1
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Long-term efficacy and safety of renal denervation: an update from registries and randomised trials

Kyriakos Dimitriadisa First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, GreeceCorrespondence[email protected]
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,
Roland E. Schmiederb Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich Alexander University Erlangen Nürnberg, Erlangen, Germany (R.E.S)View further author information
,
Panagiotis Iliakisa First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, GreeceView further author information
,
Laura Nickelc Medizinische Klinik II, Sana Kliniken Lübeck GmbH, Lübeck, GermanyView further author information
,
Konstantinos Tsioufisa First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, GreeceView further author information
&
Joachim Weilc Medizinische Klinik II, Sana Kliniken Lübeck GmbH, Lübeck, GermanyView further author information
Article: 2266664 | Received 28 Aug 2023, Accepted 30 Sep 2023, Published online: 07 Oct 2023

References

  • Schmieder RE, Mahfoud F, Mancia G, et al. Members of the ESH working group on Device-Based treatment of hypertension. European society of hypertension position paper on renal denervation 2021. J Hypertens. 2021;39(9):1–4. doi:10.1097/HJH.0000000000002933.
  • Sharp ASP, Tunev S, Schlaich M, et al. Histological evidence supporting the durability of successful radiofrequency renal denervation in a normotensive porcine model. J Hypertens. 2022;40(10):2068–2075. doi:10.1097/HJH.0000000000003236.
  • Delgado-Silva J, Fernandes R, Pita IR, et al. Intravascular imaging, histopathological analysis, and catecholamine quantification following catheter-based renal denervation in a swine model: the impact of prebifurcation energy delivery. Hypertens Res. 2018;41(9):708–717. doi:10.1038/s41440-018-0072-y.
  • Singh RR, McArdle ZM, Iudica M, et al. Sustained decrease in blood pressure and reduced anatomical and functional reinnervation of renal nerves in hypertensive sheep 30 months after Catheter-Based renal denervation. Hypertension. 2019;73(3):718–727. doi:10.1161/HYPERTENSIONAHA.118.12250.
  • Mahfoud F, Böhm M, Schmieder R, et al. Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the global SYMPLICITY registry. Eur Heart J. 2019;40(42):3474–3482. doi:10.1093/eurheartj/ehz118.
  • Sesa-Ashton G, Nolde JM, Muente I, et al. Catheter-Based renal denervation: 9-Year Follow-Up data on safety and blood pressure reduction in patients with resistant hypertension. Hypertension. 2023;80(4):811–819. doi:10.1161/HYPERTENSIONAHA.122.20853.
  • Zeijen VJM, Theuns DA, Feyz L, et al. Long-term safety and efficacy of renal sympathetic denervation in atrial fibrillation: 3-year results of the AFFORD study. Clin Res Cardiol. 2023. doi:10.1007/s00392-023-02222-3.
  • Al Ghorani H, Kulenthiran S, Recktenwald MJM, et al. 10-Year outcomes of Catheter-Based renal denervation in patients with resistant hypertension. J Am Coll Cardiol. 2023;81(5):517–519. doi:10.1016/j.jacc.2022.11.038.
  • Mahfoud F, Kandzari DE, Kario K, et al. Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial. Lancet. 2022;399(10333):1401–1410. doi:10.1016/S0140-6736(22)00455-X.
  • Rader F, Kirtane AJ, Wang Y, et al. Durability of blood pressure reduction after ultrasound renal denervation: three-year follow-up of the treatment arm of the randomised RADIANCE-HTN SOLO trial. EuroIntervention. 2022;18(8):e677–e685. doi:10.4244/EIJ-D-22-00305.

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