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Research Articles

Exploring levels of TSH and FT4 in patients with chronic fatigue syndrome (CFS), fibromyalgia (FM) and healthy controls did not reveal any associations between fatigue score and level of thyroid hormones

, , ORCID Icon & ORCID Icon
Pages 376-381 | Received 27 Nov 2023, Accepted 12 Mar 2024, Published online: 01 Apr 2024

References

  • Groven N, Fors EA, Stunes AK, et al. MCP-1 is increased in patients with CFS and FM, whilst several other immune markers are significantly lower than healthy controls. Brain Behav Immun Health. 2020;4:100067. doi: 10.1016/J.BBIH.2020.100067.
  • Rodriguez-Pintó I, Agmon-Levin N, Howard A, et al. Fibromyalgia and cytokines. Immunol Lett. 2014;161(2):200–203. doi: 10.1016/J.IMLET.2014.01.009.
  • Mease P. Fibromyalgia syndrome: review of clinical presentation, pathogenesis, outcome measures, and treatment. J Rheumatol Suppl. 2005;75:6–21.
  • Fukuda K, Straus SE, Hickie I, et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121(12):953–959. doi: 10.7326/0003-4819-121-12-199412150-00009.
  • Linder J, Ekholm KS, Jansen GB, et al. Long-term sick leavers with difficulty in resuming work: comparisons between psychiatric-somatic comorbidity and monodiagnosis. Int J Rehabil Res. 2009;32(1):20–35. doi: 10.1097/MRR.0B013E328306351D.
  • Noor N, Urits I, Degueure A, et al. A comprehensive update of the current understanding of chronic fatigue syndrome. Anesth Pain Med. 2021 11:3, 2021;11(3):e113629. doi: 10.5812/AAPM.113629.
  • Lim EJ, Ahn YC, Jang ES, et al. Systematic review and meta-analysis of the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). J Transl Med. 2020;18(1):100. doi: 10.1186/s12967-020-02269-0.
  • Groven N, Fors EA, Reitan SK. Patients with fibromyalgia and chronic fatigue syndrome show increased hsCRP compared to healthy controls. Brain Beh′av Immun. 2019;81:172–177. doi: 10.1016/j.bbi.2019.06.010.
  • Sweetman E, Kleffmann T, Edgar C, et al. A SWATH-MS analysis of myalgic encephalomyelitis/chronic fatigue syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction. J Transl Med. 2020;18(1):365. doi: 10.1186/s12967-020-02533-3.
  • Wirth K, Scheibenbogen C. A unifying hypothesis of the pathophysiology of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): recognitions from the finding of autoantibodies against ß2-adrenergic receptors. Autoimmun Rev. 2020;19(6):102527. doi: 10.1016/J.AUTREV.2020.102527.
  • Chiovato L, Magri F, Carlé A. Hypothyroidism in context: where we’ve been and where we’re going. Adv Ther. 2019;36(Suppl 2):47–58. doi: 10.1007/S12325-019-01080-8.
  • Sakai Y, Iversen V, Reitan SK. FT4 and TSH, relation to diagnoses in an unselected psychiatric acute-ward population, and change during acute psychiatric admission. BMC Psychiatry. 2018;18(1):244. doi: 10.1186/s12888-018-1819-3.
  • Wyller VB, Vitelli V, Sulheim D, et al. Altered neuroendocrine control and association to clinical symptoms in adolescent chronic fatigue syndrome: a cross-sectional study. J Transl Med. 2016;14(1):121. doi: 10.1186/s12967-016-0873-1.
  • Moorkens G, Berwaerts J, Wynants H, et al. Characterization of pituitary function with emphasis on GH secretion in the chronic fatigue syndrome. Clin Endocrinol (Oxf). 2000;53(1):99–106. doi: 10.1046/J.1365-2265.2000.01049.X.
  • Ruiz-Núñez B, Tarasse R, Vogelaar EF, et al. Higher prevalence of “low T3 syndrome” in patients with chronic fatigue syndrome: a case-control study. Front Endocrinol (Lausanne). 2018;9:97. (MAR), doi: 10.3389/FENDO.2018.00097/BIBTEX.
  • Tomic S, Brkic S, Lendak D, et al. Neuroendocrine disorder in chronic fatigue syndrome. Turk J Med Sci. 2017;47(4):1097–1103. doi: 10.3906/SAG-1601-110.
  • Siracusa R, Di Paola R, Cuzzocrea S, et al. Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update. Int J Mol Sci. 2021;22(8):3891. doi: 10.3390/IJMS22083891.
  • Wolfe F, Clauw DJ, Fitzcharles MA, et al. 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria. Semin Arthritis Rheum. 2016;46(3):319–329. doi: 10.1016/J.SEMARTHRIT.2016.08.012.
  • Garrison RL, Breeding PC. A metabolic basis for fibromyalgia and its related disorders: the possible role of resistance to thyroid hormone. Med Hypotheses. 2003;61(2):182–189. doi: 10.1016/s0306-9877(02)00294-3.
  • Aloisi AM, Vodo S, Buonocore M. Pain and thyroid hormones. Neurol Sci. 2013;34(9):1501–1508. doi: 10.1007/S10072-013-1440-7.
  • Jordan B, Uer O, Buchholz T, et al. Physical fatigability and muscle pain in patients with hashimoto thyroiditis. J Neurol. 2021;268(7):2441–2449. doi: 10.1007/S00415-020-10394-5.
  • Ørstavik K, Norheim I, Jørum E. Pain and small-fiber neuropathy in patients with hypothyroidism. Neurology. 2006;67(5):786–791. doi: 10.1212/01.WNL.0000234035.13779.4A.
  • Lowe J, Yellin J, Lowe GH. Female fibromyalgia patients: lower resting metabolic rates than matched healthy controls. Europepmc.Org, 2006. https://europepmc.org/article/med/16810133.
  • Park S, Kwon JS, Park YB, et al. Is thyroid autoimmunity a predisposing factor for fibromyalgia? A systematic review and meta-analysis. Clin Exp Rheumatol. 2022;40(6):1210–1220. doi: 10.55563/clinexprheumatol/y3gfva.
  • Riedel W, Layka H, Neeck G. Secretory pattern of GH, TSH, thyroid hormones, ACTH, cortisol, FSH, and LH in patients with fibromyalgia syndrome following systemic injection of the relevant hypothalamic-releasing hormones. Z Rheumatol. 1998;57 (SUPPL. 2):81–87. doi: 10.1007/S003930050242.
  • Wolfe F, Smythe HA, Yunus MB, et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Arthritis Rheum. 1990;33(2):160–172. doi: 10.1002/art.1780330203.
  • Bjelland I, Dahl AA, Haug TT, et al. The validity of the hospital anxiety and depression scale: an updated literature review. J Psychosom Res. 2002;52(2):69–77. doi: 10.1016/S0022-3999(01)00296-3.
  • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370. doi: 10.1111/J.1600-0447.1983.TB09716.X.
  • Chalder T, Berelowitz G, Pawlikowska T, et al. Development of a fatigue scale. J Psychosom Res. 1993;37(2):147–153. doi: 10.1016/0022-3999(93)90081-P.
  • Loge JH, Ekeberg Ø, Kaasa S. Fatigue in the general Norwegian population: normative data and associations. J Psychosom Res. 1998;45(1):53–65. doi: 10.1016/S0022-3999(97)00291-2.
  • Wolfe F, Häuser W. Fibromyalgia diagnosis and diagnostic criteria. Ann Med. 2011;43(7):495–502. doi: 10.3109/07853890.2011.595734.
  • Cleeland CS. Pain assesment in cancer. In D. Osoba (Ed.), Effect of cancer on quality of life. Boca Ration: CRC Press; 1991, pp. 293–305.
  • Klepstad P, Loge JH, Borchgrevink PC, et al. The norwegian brief pain inventory questionnaire: translation and validation in cancer pain patients. J Pain Symptom Manage. 2002;24(5):517–525. doi: 10.1016/S0885-3924(02)00526-2.
  • Suk JH, Lee JH, Kim JM. Association between thyroid autoimmunity and fibromyalgia. Exp Clin Endocrinol Diabetes. 2012;120(7):401–404. doi: 10.1055/s-0032-1309008.
  • Haliloglu S, Ekinci B, Uzkeser H, et al. Fibromyalgia in patients with thyroid autoimmunity: prevalence and relationship with disease activity. Clin Rheumatol. 2017;36(7):1617–1621. doi: 10.1007/S10067-017-3556-2/TABLES/3.
  • Ruíz-Pacheco MG, Hernández I, Hernández-Estrella G, et al. Severity of fatigue and its relationship with TSH before and after levothyroxine replacement therapy in patients with primary hypothyroidism. Biomedicines. 2023;11(3):811. doi: 10.3390/BIOMEDICINES11030811.
  • Tjørve E, Tjørve KMC, Olsen JO, et al. On commonness and rarity of thyroid hormone resistance: a discussion based on mechanisms of reduced sensitivity in peripheral tissues. Med Hypotheses. 2007;69(4):913–921. doi: 10.1016/J.MEHY.2006.12.056.
  • Groven N, Reitan SK, Fors EA, et al. Kynurenine metabolites and ratios differ between chronic fatigue syndrome, fibromyalgia, and healthy controls. Psychoneuroendocrinology. 2021;131:105287. doi: 10.1016/j.psyneuen.2021.105287.