Publication Cover
Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 46, 2017 - Issue 2
97
Views
13
CrossRef citations to date
0
Altmetric
Original Articles

IL12 Gene Polymorphism in Association with Hepatocellular Carcinoma in HCV-infected Egyptian Patients

, &

References

  • Chen X, Han S, Wang S, et al. (2009). Interactions of IL-12A and IL-12B polymorphisms on the risk of cervical cancer in Chinese women. Clin Cancer Res, 15, 400–405.
  • Colombo MP, Trinchieri G. (2002). Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev, 13, 155–168.
  • Donato F, Tagger A, Chiesa R, et al. (1997). Hepatitis B and C virus infection, alcohol drinking, and hepatocellular carcinoma: a case-control study in Italy. Brescia HCC Study. Hepatology, 26, 579–584.
  • Egyptian Ministry of Health. (2007). Egyptian Ministry of Health Annual Report. Available at http://www.mohp.gov.eg/main (accessed 2 May 2015).
  • El-Nady GM, Ling R, Harrison TJ. (2003). Gene expression in HCV-associated hepatocellular carcinoma–upregulation of a gene encoding a protein related to the ubiquitin-conjugating enzyme. Liver Int, 23, 329–337.
  • El-Zanaty F, Way A. (2009). Egypt Demographic and Health Survey 2008. Egypt: Ministry of Health. Cairo: El-Zanaty and Associates, and Macro International.
  • El-Zayadi AR, Badran HM, Barakat EM, et al. (2005). Hepatocellular carcinoma in Egypt: a single center study over a decade. World J Gastroenterol, 11, 5193–5198.
  • Farooqi ZR, Afzal MS, Tahir S, et al. (2011). Interleukin-12 P40 (IL-12 B) Taq-1 Polymorphism association in pharmacogenomics of HCV genotype 3a infection from Pakistani population. NUST Center of Virology and Immunology (NCVI), National University of Sciences and Technology, Islamabad, Pakistan. International Conference on Environmental, Biomedical and Biotechnology IPCBEE vol. 16, IACSIT Press, Singapore.
  • Grzegorzewska AE, Wobszal PM, Mostowska A, and Jagodziński PP. (2012). Antibodies to hepatitis B virus surface antigen and interleukin 12 and interleukin 18 gene polymorphisms in hemodialysis patients. BMC Nephrol, 13, 75.
  • Houldsworth A, Metzner M, Rossol S, et al. (2005). Polymorphisms in the IL-12B gene and outcome of HCV infection. Interferon Cytokine Res, 25(5), 271–276.
  • Ibrahim AS, Khaled HM, Mikhail NN, et al. (2014). Cancer incidence in Egypt: results of the national population-based cancer registry program. J Cancer Epidemiol, 2014, 437971.
  • Liang TJ, Heller T. (2004). Pathogenesis of hepatitis C-associated hepatocellular carcinoma. Gastroenterol, 127, S62–S71.
  • Liu L, Xu Y, Liu Z, et al. (2011). IL12 polymorphisms, HBV infection and risk of hepatocellular carcinoma in a high-risk Chinese population. J Cancer, 128, 1692–1696.
  • Mohamoud YA, Mumtaz GR, Riome S, et al. (2013). The epidemiology of hepatitis C virus in Egypt: a systematic review and data synthesis. BMC Infect Dis, 13, 288.
  • Nieters A, Yuan JM, Sun CL, et al. (2005). Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association. Cancer, 103(4), 740–748.
  • Peng Q, Li S, Lao X, et al. (2014). Interleukin-12B+1188A/C polymorphism contributes to increased hepatocellular carcinoma susceptibility: evidence from a meta-analysis. Clin Res Hepatol Gastroenterol, 38(6), 735–743.
  • Shaw-Stiffel TA. (2000). Chronic hepatitis. In: Mandell GL, Bennett JE, Dolin R, et al., eds. Principles and Practice of Infectious Diseases (5th edition). New York: Churchill Livingstone, 1297–1321.
  • Tan A, Gao Y, Yao Z, et al. (2015). Genetic variants in IL12 influence both hepatitis B virus clearance and HBV-related hepatocellular carcinoma development in a Chinese male population. Tumour Biol, 37(5), 6343–6348.
  • Tanaka Y, Agha S, Saudy N, et al. (2004). Exponential spread of hepatitis C virus genotype 4a in Egypt. J Mol Evol, 58, 191–195.
  • Trinchieri G. (2003). Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol, 3, 133–146.
  • World Health Organization, A63/15. (2010). Available at http://apps.who.int/gb/ebwha/pdf_files/WHA63/A63_15-en.pdf. Viral hepatitis. Sixty third world health assembly Provisional agenda item 11.12.
  • Yates SC, Hafez M, Beld M, et al. (1999). Hepatocellular carcinoma in Egyptians with and without a history of hepatitis B virus infection: association with hepatitis C virus (HCV) infection but not with (HCV) RNA level. Am J Trop Med Hyg, 60, 714–720.
  • Yeh CT, Chen TC, Chang ML, et al. (2007). Identification of NV-F virus DNA in hepatocellular carcinoma. J Med Virol, 79, 92–96.
  • Yin L, Zhu W, Wei L, et al. (2004). Association of interleukin-12 p40 gene 3’-untranslated region polymorphism and outcome of HCV infection. World J Gastroenterol, 10 (16), 2330–2333.
  • Youssef SS, Abd El Aal AM, Nasr AS, et al. (2013). Interleukin-12B gene polymorphism frequencies in Egyptians and sex-related susceptibility to hepatitis C infection. Interferon Cytokine Res, 33 (8), 415–419.
  • Yu L, Sun L, Jiang YF, et al. (2012). Interactions between CYP1A1 polymorphisms and cigarette smoking are associated with the risk of hepatocellular carcinoma: evidence from epidemiological studies. Mol Biol Rep, 39, 6641–6646.
  • Yuzhalin AE, Kutikhin AG. (2012). Interleukin-12: clinical usage and molecular markers of cancer susceptibility. Growth Factors, 30(3), 176–191.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.