Tamoxifen Attenuates Lipopolysaccharide/Galactosamine-induced Acute Liver Failure by Antagonizing Hepatic Inflammation and Apoptosis

References

• Ai G, et al. (2013). Hepatoprotective evaluation of the total flavonoids extracted from flowers of Abelmoschus manihot (L.) Medic: In vitro and in vivo studies. J Ethnopharmacol, 146(3),794–802.
   Google Scholar
• Bantel H, Schulze-Osthoff K. (2012). Mechanisms of cell death in acute liver failure. Frontiers Physiol, 3, 79.
   PubMed Web of Science ®Google Scholar
• Callaghan R, Higgins CF. (1995). Interaction of tamoxifen with the multidrug resistance P-glycoprotein. Br J Cancer, 71(2),294–299.
   Google Scholar
• Dhingra K. (1999). Antiestrogens–tamoxifen, SERMs and beyond. Invest New Drugs, 17(3),285–311.
   PubMed Web of Science ®Google Scholar
• Feingold KR, et al. (1988). Tumor necrosis factor stimulates DNA synthesis in the liver of intact rats. Biochem Biophys Res Commun, 153(2),576–582.
   Google Scholar
• Gieling RG, et al. (2009). Interleukin-1 participates in the progression from liver injury to fibrosis. Am J Physiol Gastrointest Liver Physiol, 296(6),G1324–G1331.
   PubMed Web of Science ®Google Scholar
• Grainger DJ, Schofield PM. (2005). Tamoxifen for the prevention of myocardial infarction in humans: preclinical and early clinical evidence. Circulation, 112(19),3018–3024.
   Google Scholar
• Ilyas G, et al. (2016). Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1beta. J Hepatol, 64(1),118–127.
   PubMed Web of Science ®Google Scholar
• Ismail AF, et al. (2016). Hepatoprotective effect of grape seed oil against carbon tetrachloride induced oxidative stress in liver of gamma-irradiated rat. J Photochem Photobiol B, 160, 1–10.
   PubMed Web of Science ®Google Scholar
• Jordan VC. (2006). The science of selective estrogen receptor modulators: concept to clinical practice. Clin Cancer Res, 12(17),5010–5013.
   Google Scholar
• Kuhla A, et al. (2008). Hepatocellular apoptosis is mediated by TNFalpha-dependent Fas/FasLigand cytotoxicity in a murine model of acute liver failure. Apoptosis, 13(12),1427–1438.
   Google Scholar
• Kuhla A, et al. (2009). Role of the perforin/granzyme cell death pathway in D-Gal/LPS-induced inflammatory liver injury. Am J Physiol Gastrointestinal Liver Physiol, 296(5),G1069–G1076.
   Google Scholar
• Kuiper GG, et al. (1997). Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology, 138(3),863–870.
   Google Scholar
• Leist M, et al. (1994). Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. J Immunol, 153(4),1778–88.
   Google Scholar
• Leist M, et al. (1997). Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. Gastroenterology, 112(3),923–934.
   Google Scholar
• Liu LM, et al. (2008). A role of cell apoptosis in lipopolysaccharide (LPS)-induced nonlethal liver injury in D-galactosamine (D-GalN)-sensitized rats. Dig Dis Sci, 53(5),1316–1324.
   Google Scholar
• Lohse AW, et al. (2010). Immune-mediated liver injury. J Hepatol, 52(1),136–144.
   Google Scholar
• Luo M, et al. (2015). Acute liver injury attenuation of a novel recombinant sTNFR through blocking hepatic apoptosis. Immunopharmacol Immunotoxicol, 37(3),295–300.
   Google Scholar
• Maes M, et al. (2016). Experimental models of hepatotoxicity related to acute liver failure. Toxicol Appl Pharmacol, 290, 86–97.
   PubMed Web of Science ®Google Scholar
• Miyashita T, et al. (2012). Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models. J Toxicol Sci, 37(5),931–942.
   Google Scholar
• Pham CG, et al. (2004). Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell, 119(4),529–542.
   Google Scholar
• Prossnitz ER, et al. (2008). The ins and outs of GPR30: a transmembrane estrogen receptor. J Steroid Biochem Mol Biol, 109(3–5), 350–353.
   PubMed Web of Science ®Google Scholar
• Rutherford A, Chung RT. (2008). Acute liver failure: mechanisms of hepatocyte injury and regeneration. Semin Liver Dis, 28(2),167–174.
   Google Scholar
• Schmich K, et al. (2011). Tumor necrosis factor alpha sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner. Hepatology, 53(1),282–292.
   PubMed Web of Science ®Google Scholar
• Sener G, et al. (2005). Estrogen protects the liver and intestines against sepsis-induced injury in rats. J Surg Res, 128(1),70–78.
   Google Scholar
• Shimizu T, et al. (2007). The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage. J Hepatol, 46(6),1047–1054.
   Google Scholar
• Tan H, et al. (2016). Trillin Reduces Liver Chronic Inflammation and Fibrosis in Carbon Tetrachloride (CCl4) Induced Liver Injury in Mice. Immunol Invest, 45(5),371–382.
   PubMed Web of Science ®Google Scholar
• Tukov FF, et al. (2007). The role of tumor necrosis factor alpha in lipopolysaccharide/ranitidine-induced inflammatory liver injury. Toxicol Sci, 100(1),267–280.
   Google Scholar
• Wang K. (2014). Molecular mechanisms of hepatic apoptosis. Cell Death Dis, 5, e996.
   PubMed Web of Science ®Google Scholar
• Wei L, et al. (2014). Oxidative stress promotes D-GalN/LPS-induced acute hepatotoxicity by increasing glycogen synthase kinase 3beta activity. Inflammation Res, 63(6),485–194.
   PubMed Web of Science ®Google Scholar
• Wu Z, et al. (2010). Acute liver failure: mechanisms of immune-mediated liver injury. Liver Int, 30(6),782–794.
   Google Scholar
• Yoshikawa Y, et al. (2012). Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries. Toxicol Appl Pharmacol, 264(1),42–50.
   Google Scholar