References
- Amaravadi R, Kimmelman AC, White E. 2016. Recent insights into the function of autophagy in cancer. Genes Dev. 30(17):1913–30.
- Antunes F, Erustes AG, Costa AJ, et al. 2018. Autophagy and intermittent fasting: the connection for cancer therapy? Clinics (Sao Paulo). 73(suppl 1):e814s.
- Ávalos Y, Canales J, Bravo-Sagua R, et al. 2014. Tumor suppression and promotion by autophagy. Biomed Res Int. 2014:603980.
- Barbosa MC, Grosso RA, Fader CM. 2018. Hallmarks of aging: an autophagic perspective. Front Endocrinol (Lausanne). 9:790.
- Bhattacharjee A, Szabó Á, Csizmadia T, et al. 2019. Understanding the importance of autophagy in human diseases using Drosophila. J Genet Genomics. 46(4):157–69.
- Birgisdottir Å, Mouilleron S, Bhujabal Z, et al. 2019. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 15(8):1333–55.
- Bousquet G, El Bouchtaoui M, Sophie T, et al. 2017. Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer. Oncotarget. 8(21):35205–21.
- Butler DE, Marlein C, Walker HF, et al. 2017. Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer. Oncotarget. 8(34):56698–713.
- Chen N, Karantza-Wadsworth V. 2009. Role and regulation of autophagy in cancer. Biochim Biophys Acta. 1793(9):1516–23.
- Choi KS. 2012. Autophagy and cancer. Exp Mol Med. 44(2):109–20.
- Dalby KN, Tekedereli I, Lopez-Berestein G, et al. 2010. Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy. 6(3):322–29.
- Degenhardt K, Mathew R, Beaudoin B, et al. 2006. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell. 10(1):51–64.
- Fang Y, Vilella-Bach M, Bachmann R, et al. 2001. Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science. 294(5548):1942–45.
- Galluzzi L, Bravo-San Pedro JM, Vitale I, et al. 2015a. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 22(1):58–73.
- Galluzzi L, Pietrocola F, Bravo-San Pedro JM, et al. 2015b. Autophagy in malignant transformation and cancer progression. Embo J. 34(7):856–80.
- Galluzzi L, Vitale I, Abrams JM, et al. 2012. Molecular definitions of cell death subroutines: recommendations of the nomenclature committee on cell death 2012. Cell Death Differ. 19(1):107–20.
- Glick D, Barth S, Macleod KF. 2010. Autophagy: cellular and molecular mechanisms. J Pathol. 221(1):3–12.
- Guo W, Wang Y, Wang Z, et al. 2016. Inhibiting autophagy increases epirubicin’s cytotoxicity in breast cancer cells. Cancer Sci. 107(11):1610–21.
- Hanahan D, Weinberg RA. 2011. Hallmarks of cancer: the next generation. Cell. 144(5):646–74.
- Hao Y, Kacal M, Ouchida AT, et al. 2019. Targetome analysis of chaperone-mediated autophagy in cancer cells. Autophagy. 15(9):1558–71.
- Hippert MM, O’Toole PS, Thorburn A. 2006. Autophagy in cancer: good, bad, or both? Cancer Res. 66(19):9349–51.
- Huang Z, Zhou L, Chen Z, et al. 2016. Stress management by autophagy: implications for chemoresistance. Int J Cancer. 139(1):23–32.
- Kardideh B, Samimi Z, Norooznezhad F, et al. 2019. Autophagy, cancer and angiogenesis: where is the link? Cell Biosci. 9(1):65.
- Leonardi M, Perna E, Tronnolone S, et al. 2018. Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy. Autophagy. 15(2):312–26.
- Levine B, Yuan J. 2005. Autophagy in cell death: an innocent convict? J Clin Invest. 115(10):2679–88.
- Li N, Fan X, Wang X, et al. 2019. Autophagy-related 5 gene rs510432 polymorphism is associated with hepatocellular carcinoma in patients with chronic hepatitis B virus infection. Immunol Invest. 48(4):378–91.
- Liang DH, El-Zein R, Dave B. 2015. Autophagy inhibition to increase radiosensitization in breast cancer. J Nucl Med Radiat Ther. 6(5):254.
- Lin L, Baehrecke EH. 2015. Autophagy, cell death, and cancer. Mol Cell Oncol. 2(3):e985913.
- Lin SR, Fu YS, Tsai MJ, et al. 2017. Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy. Int J Mol Sci. 18(7):1412.
- Magryś A, Bogut A, Kiełbus M, et al. 2018. The role of the PI3K/mTOR signaling pathway in Staphylococcus epidermidis small colony variants intracellular survival. Immunol Invest. 47(3):251–63.
- Mizushima N, Komatsu M. 2011. Autophagy: renovation of cells and tissues. Cell. 147(4):728–41.
- Mizushima N, Levine B, Cuervo AM, et al. 2008. Autophagy fights disease through cellular self-digestion. Nature. 451(7182):1069–75.
- Moreau K, Luo S, Rubinsztein DC. 2010. Cytoprotective roles for autophagy. Curr Opin Cell Biol. 22(2):206–11.
- Naponelli V, Modernelli A, Bettuzzi S, et al. 2015. Roles of autophagy induced by natural compounds in prostate cancer. Biomed Res Int. 2015:121826.
- Ndoye A, Weeraratna AT. 2016. Autophagy - an emerging target for melanoma therapy. F1000Res. 5 ( F1000 Faculty Rev):1888. doi:10.12688/f1000research.
- O’Donnell JS, Massi D, MWL T, et al. 2018. PI3K-AKT-mTOR inhibition in cancer immunotherapy, redux. Semin Cancer Biol. 48:91–103.
- Orvedahl A, Levine B. 2009. Eating the enemy within: autophagy in infectious diseases. Cell Death Differ. 16(1):57–69.
- Paglin S, Lee NY, Nakar C, et al. 2005. Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells. Cancer Res. 65(23):11061–70.
- Sharif T, Martell E, Dai C, et al. 2017. Autophagic homeostasis is required for the pluripotency of cancer stem cells. Autophagy. 13(2):264–84.
- Sharma K, Le N, Alotaibi M, et al. 2014. Cytotoxic autophagy in cancer therapy. Int J Mol Sci. 15(6):10034–51.
- Shen HM, Codogno P. 2011. Autophagic cell death: loch Ness monster or endangered species? Autophagy. 7(5):457–65.
- Sun L, Liu N, Liu SS, et al. 2015. Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia. Am J Cancer Res. 5(9):2626–42.
- Wen X, Klionsky DJ. 2016. An overview of macroautophagy in yeast. J Mol Biol. 428(9Pt A):1681–99.
- White E, Mehnert JM, Chan CS. 2015. Autophagy, metabolism, and cancer. Clin Cancer Res. 21(22):5037–46.
- Wu YT, Tan HL, Shui G, et al. 2010a. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem. 285(14):10850–61.
- Wu Z, Chang PC, Yang JC, et al. 2010b. Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors. Genes Cancer. 1(1):40–49.
- Yang J, Nie J, Ma X, et al. 2019. Targeting PI3K in cancer: mechanisms and advances in clinical trials. Mol Cancer. 18(1):26.
- Yang ZJ, Chee CE, Huang S, et al. 2011. The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther. 10(9):1533–41.
- Zachari M, Ganley IG. 2017. The mammalian ULK1 complex and autophagy initiation. Essays Biochem. 61(6):585–96.
- Zarzynska JM. 2014. The importance of autophagy regulation in breast cancer development and treatment. Biomed Res Int. 2014:710345.
- Zhi X, Zhong Q. 2015. Autophagy in cancer. F1000Prime Rep. 7:18.
- Zhou Y, Rucker EB, Zhou BP. 2016. Autophagy regulation in the development and treatment of breast cancer. Acta Biochim Biophys Sin (Shanghai). 48(1):60–74.