Dysregulated Expression of miR-146a and Its Associated Immune Effectors in Peripheral Blood Mononuclear Cells of Esophageal Carcinoma Patients

References

• Arenas-Padilla M, Mata-Haro V. 2018. Regulation of TLR signaling pathways by microRNAs: implications in inflammatory diseases. Cent Eur J Immunol. 43(4):482–89.
   PubMed Web of Science ®Google Scholar
• Baine MJ, Menning M, Smith LM, Mallya K, Kaur S, Rachagani S, Chakraborty S, Sasson AR, Brand RE, Batra SK. 2011. Differential gene expression analysis of peripheral blood mononuclear cells reveals novel test for early detection of pancreatic cancer. Cancer Biomark. 11(1):1–14. doi:https://doi.org/10.3233/cbm-2012-0260.
   PubMed Web of Science ®Google Scholar
• Bell E. 2007. MicroRNAs and the immune response. Nat Rev Immunol. 7(6):419.
   Web of Science ®Google Scholar
• Chang CC, Lin CC, Hsieh WL, Lai HW, Tsai CH, Cheng YW. 2014. MicroRNA expression profiling in PBMCs: a potential diagnostic biomarker of chronic hepatitis C. Dis Markers. 2014:367157.
   PubMed Web of Science ®Google Scholar
• Chang DH, Rutledge JR, Patel AA, Heerdt BG, Augenlicht LH, Korst RJ. 2013. The effect of lung cancer on cytokine expression in peripheral blood mononuclear cells. PLoS One. 8(6):e64456.
   PubMed Web of Science ®Google Scholar
• Chang P, Wang X, Zhou Y, Hou Y. 2017. Analysis of the correlation between the expression of miR-655 and esophageal cancer prognosis. Oncol Lett. 13(6):4691–94.
   PubMed Web of Science ®Google Scholar
• Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, Nguyen JT, Barbisin M, Xu NL, Mahuvakar VR, Andersen MR, et al. 2005. Real-time quantification of microRNAs by stem–loop RT–PCR. Nucleic Acids Res. 33(20):e179. doi:https://doi.org/10.1093/nar/gni178.
   PubMed Web of Science ®Google Scholar
• Chen G, Umelo IA, Lv S, Teugels E, Fostier K, Kronenberger P, Dewaele A, Sadones J, Geers C, De Grève J, et al. 2013. miR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells. PLoS One. 8(3):e60317. doi:https://doi.org/10.1371/journal.pone.0060317.
   PubMed Web of Science ®Google Scholar
• Djaldetti M, Bessler H. 2014. Modulators affecting the immune dialogue between human immune and colon cancer cells. World J Gastrointest Oncol. 6(5):129–38.
   PubMed Web of Science ®Google Scholar
• Florcken A, Grau M, Wolf A, Weilemann A, Kopp J, Dorken B, Blankenstein T, Pezzutto A, Lenz P, Lenz G, et al. 2015. Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-kappaB. Int J Cancer. 136(8):1814–26. doi:https://doi.org/10.1002/ijc.29230.
   PubMed Web of Science ®Google Scholar
• Gupta MK, Halley C, Duan ZH, Lappe J, Viterna J, Jana S, Augoff K, Mohan ML, Vasudevan NT, Na J, et al. 2013. miRNA-548c: a specific signature in circulating PBMCs from dilated cardiomyopathy patients. J Mol Cell Cardiol. 62:131–41.
   PubMed Web of Science ®Google Scholar
• Hellemans J, Mortier G, De Paepe A, Speleman F, Vandesompele J. 2007. qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol. 8(2):R19.
   PubMed Web of Science ®Google Scholar
• Ida S, Watanabe M, Baba H. 2015. Chronic inflammation and gastrointestinal cancer. J Cancer Metastasis Treat. 1(3):138–43.
   Google Scholar
• Karin M, Greten FR. 2005. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol. 5(10):749–59.
   PubMed Web of Science ®Google Scholar
• Kumaraswamy E, Wendt KL, Augustine LA, Stecklein SR, Sibala EC, Li D, Gunewardena S, Jensen RA. 2015. BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor function. Oncogene. 34(33):4333–46.
   PubMed Web of Science ®Google Scholar
• Li Y, Vandenboom TG 2nd, Wang Z, Kong D, Ali S, Philip PA, Sarkar FH. 2010. miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res. 70(4):1486–95.
   PubMed Web of Science ®Google Scholar
• Liang H, Fan JH, Qiao YL. 2017. Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China. Cancer Biol Med. 14(1):33–41.
   PubMed Web of Science ®Google Scholar
• Lin EW, Karakasheva TA, Hicks PD, Bass AJ, Rustgi AK. 2016. The tumor microenvironment in esophageal cancer. Oncogene. 35(41):5337–49.
   PubMed Web of Science ®Google Scholar
• Ma J, Lin Y, Zhan M, Mann DL, Stass SA, Jiang F. 2015. Differential miRNA expressions in peripheral blood mononuclear cells for diagnosis of lung cancer. Lab Invest. 95(10):1197–206.
   PubMed Web of Science ®Google Scholar
• Mehta A, Baltimore D. 2016. MicroRNAs as regulatory elements in immune system logic. Nat Rev Immunol. 16(5):279–94.
   PubMed Web of Science ®Google Scholar
• Mytar B, Woloszyn M, Szatanek R, Baj-Krzyworzeka M, Siedlar M, Ruggiero I, Wieckiewicz J, Zembala M. 2003. Tumor cell-induced deactivation of human monocytes. J Leukoc Biol. 74(6):1094–101.
   PubMed Web of Science ®Google Scholar
• Nariman-Saleh-Fam Z, Vahed SZ, Aghaee-Bakhtiari SH, Daraei A, Saadatian Z, Kafil HS, Yousefi B, Eyvazi S, Khaheshi I, Parsa SA. 2019. Expression pattern of miR-21, miR-25 and PTEN in peripheral blood mononuclear cells of patients with significant or insignificant coronary stenosis. Gene. 698:170–78.
   PubMed Web of Science ®Google Scholar
• Paterson MR, Kriegel AJ. 2017. MiR-146a/b: a family with shared seeds and different roots. Physiol Genomics. 49(4):243–52.
   PubMed Web of Science ®Google Scholar
• Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EK. 2008. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther. 10(4):R101.
   PubMed Web of Science ®Google Scholar
• Philippidou D, Schmitt M, Moser D, Margue C, Nazarov PV, Muller A, Vallar L, Nashan D, Behrmann I, Kreis S. 2010. Signatures of microRNAs and selected microRNA target genes in human melanoma. Cancer Res. 70(10):4163–73. doi:https://doi.org/10.1158/0008-5472.can-09-4512.
   PubMed Web of Science ®Google Scholar
• Ping FM, Liu GJ, Liu ZJ, Li HB, Zhai JW, Li SX, Liu YM, Li BW, Wei H. 2015. Expression of RKIP, E-cadherin and NF-kB p65 in esophageal squamous cell carcinoma and their correlations. Int J Clin Exp Pathol. 8(9):10164–70.
   PubMed Web of Science ®Google Scholar
• Qu X, Tang Y, Hua S. 2018. Immunological Approaches Towards Cancer and Inflammation: A Cross Talk. Front Immunol. 9:563.
   PubMed Web of Science ®Google Scholar
• Ritz C, Spiess A-N. 2008. qpcR: an R package for sigmoidal model selection in quantitative real-time polymerase chain reaction analysis. Bioinformatics. 24(13):1549–51.
   PubMed Web of Science ®Google Scholar
• Saadatian Z, Nariman-Saleh-Fam Z, Bastami M, Mansoori Y, Khaheshi I, Parsa SA, Daraei A, Vahed SZ, Yousefi B, Kafil HS, et al. 2019. Dysregulated expression of STAT1, miR-150, and miR-223 in peripheral blood mononuclear cells of coronary artery disease patients with significant or insignificant stenosis. J Cell Biochem. 120:19810–24.
   PubMed Web of Science ®Google Scholar
• Siedlar M, Szaflarska A, Szczepanik A, Ruggiero I, Frankenberger M, Szatanek R, Czupryna A, Popiela T, Zembala M. 2005. Depressed tumor necrosis factor alpha and interleukin-12p40 production by peripheral blood mononuclear cells of gastric cancer patients: association with IL-1R-associated kinase-1 protein expression and disease stage. Int J Cancer. 114(1):144–52.
   PubMed Web of Science ®Google Scholar
• Spiess A-N, Feig C, Ritz C. 2008. Highly accurate sigmoidal fitting of real-time PCR data by introducing a parameter for asymmetry. BMC Bioinform. 9(1):221.
   PubMedGoogle Scholar
• Sugihara H, Ishimoto T, Miyake K, Izumi D, Baba Y, Yoshida N, Watanabe M, Baba H. 2015. Noncoding RNA expression aberration is associated with cancer progression and is a potential biomarker in esophageal squamous cell carcinoma. Int J Mol Sci. 16(11):27824–34. doi:https://doi.org/10.3390/ijms161126060.
   PubMed Web of Science ®Google Scholar
• Sun M, Fang S, Li W, Li C, Wang L, Wang F, Wang Y. 2015. Associations of miR-146a and miR-146b expression and clinical characteristics in papillary thyroid carcinoma. Cancer Biomark. 15(1):33–40.
   PubMed Web of Science ®Google Scholar
• Taganov KD, Boldin MP, Chang KJ, Baltimore D. 2006. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA. 103(33):12481–86.
   PubMed Web of Science ®Google Scholar
• Tang H, Lai Y, Zheng J, Chen K, Jiang H, Xu G. 2020. MiR-146a promotes tolerogenic properties of dendritic cells and through targeting Notch1 signaling. Immunol Invest. 49(5):555–70.
   PubMed Web of Science ®Google Scholar
• Testa U, Pelosi E, Castelli G, Labbaye C 2017. miR-146 and miR-155: two key modulators of immune response and tumor development. Noncoding RNA. 3(3). doi:https://doi.org/10.3390/ncrna3030022
   Google Scholar
• Torre LA, Siegel RL, Ward EM, Jemal A. 2016. Global cancer incidence and mortality rates and trends–an update. Cancer Epidemiol Biomarkers Prev. 25(1):16–27.
   PubMed Web of Science ®Google Scholar
• Wang C, Guan S, Liu F, Chen X, Han L, Wang D, Nesa EU, Wang X, Bao C, Wang N. 2016. Prognostic and diagnostic potential of miR-146a in oesophageal squamous cell carcinoma. Br J Cancer. 114(3):290–97.
   PubMed Web of Science ®Google Scholar
• Wang L, Miyahira AK, Simons DL, Lu X, Chang AY, Wang C, Suni MA, Maino VC, Dirbas FM, Yim J, et al. 2017. IL6 signaling in peripheral blood T cells predicts clinical outcome in breast cancer. Cancer Res. 77(5):1119–26. doi:https://doi.org/10.1158/0008-5472.can-16-1373.
   PubMed Web of Science ®Google Scholar
• Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C, Zheng ZM. 2008. Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One. 3(7):e2557.
   PubMed Web of Science ®Google Scholar
• Wu D, Wu P, Zhao L, Huang L, Zhang Z, Zhao S, Huang J. 2015. NF-kappaB expression and outcomes in solid tumors: a systematic review and meta-analysis. Medicine (Baltimore). 94(40):e1687.
   PubMed Web of Science ®Google Scholar
• Xia L, Tan S, Zhou Y, Lin J, Wang H, Oyang L, Tian Y, Liu L, Su M, Wang H, et al. 2018. Role of the NFkappaB-signaling pathway in cancer. Onco Targets Ther. 11:2063–73. doi:https://doi.org/10.2147/ott.s161109
   PubMed Web of Science ®Google Scholar
• Yao Q, Cao Z, Tu C, Zhao Y, Liu H, Zhang S. 2013. MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2. Cancer Lett. 335(1):219–24.
   PubMed Web of Science ®Google Scholar
• Zilahi E, Tarr T, Papp G, Griger Z, Sipka S, Zeher M. 2012. Increased microRNA-146a/b, TRAF6 gene and decreased IRAK1 gene expressions in the peripheral mononuclear cells of patients with Sjogren’s syndrome. Immunol Lett. 141(2):165–68.
   PubMed Web of Science ®Google Scholar
• Zou W, Restifo NP. 2010. T(H)17 cells in tumour immunity and immunotherapy. Nat Rev Immunol. 10(4):248–56.
   PubMed Web of Science ®Google Scholar