MASP1 Gene Polymorphism and MASP-3 Serum Levels in Patients with Chronic Chagas Disease

References

• Ammitzbøll CG, Steffensen R, Jørgen Nielsen H, Thiel S, Stengaard-Pedersen K, Bøgsted M, Jensenius JC. 2013 Sept 2. Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44. PLoS One. 8(9):e73317. doi:10.1371/journal.pone.0073317. PMID: 24023860; PMCID: PMC3759447.
   PubMed Web of Science ®Google Scholar
• Andrade FA, Lidani KCF, Catarino SJ, Messias-Reason IJ. 2017 June. Serine proteases in the lectin pathway of the complement system. Proteases Physiol Pathol. 10:397–420. doi:10.1007/978-981-10-2513-6_18. PMCID: PMC7120406.
   Google Scholar
• Banda NK, Acharya S, Scheinman RI, Mehta G, Coulombe M, Takahashi M, Sekine H, Thiel S, Fujita T, Holers VM. 2016 Nov 1. Mannan-binding lectin-associated serine protease 1/3 cleavage of pro-factor D into factor D in vivo and attenuation of collagen antibody-induced arthritis through their targeted inhibition by RNA interference-mediated gene silencing. J Immunol. 197(9):3680–94. doi:10.4049/jimmunol.1600719. Epub 2016 Oct 5. PMID: 27707997; PMCID: PMC5113144.
   PubMed Web of Science ®Google Scholar
• Barroso WKS, Rodrigues CIS, Bortolotto LA, Mota-Gomes MA, Brandão AA, Feitosa ADM, Machado CA, Poli-de-Figueiredo CE, Amodeo C, Mion Júnior D, et al. 2021 Mar. Brazilian guidelines of hypertension - 2020.Arq Bras Cardiol. 116(3):516–658. English, Portuguese. doi:10.36660/abc.20201238. PMID: 33909761.
   PubMed Web of Science ®Google Scholar
• Boldt AB, Luz PR, Messias-Reason IJ. 2011 July. MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease. Clin Immunol. 140(1):63–70. doi:10.1016/j.clim.2011.03.008. Epub 2011 Mar 23. PMID: 21489885.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Chagas disease [ website]. [accessed 2021 Apr 15]. http://www.cdc.gov/parasites/chagas/index.html.
   Google Scholar
• Cestari Idos S, Krarup A, Sim RB, Inal JM, Ramirez MI. 2009 Dec. Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi. Mol Immunol. 47(2–3):426–37. doi:10.1016/j.molimm.2009.08.030. Epub 2009 Sep 27. PMID: 19783051.
   PubMed Web of Science ®Google Scholar
• Cestari I, Evans-Osses I, Schlapbach LJ, de Messias-Reason I, Ramirez MI. 2013 Apr. Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites. Mol Immunol. 53(4):328–34. doi:10.1016/j.molimm.2012.08.015. Epub 2012 Oct 9. PMID: 23063472.
   PubMed Web of Science ®Google Scholar
• Cestari I, Ramirez MI. 2010 Mar 16. Inefficient complement system clearance of Trypanosoma cruzi metacyclic trypomastigotes enables resistant strains to invade eukaryotic cells. PLoS One. 5(3):e9721. doi:10.1371/journal.pone.0009721. PMID: 20300530; PMCID: PMC2838796.
   PubMed Web of Science ®Google Scholar
• Chronic Care for Neglected Infectious Diseases. 2020. Leprosy/Hansen’s disease, lymphatic filariasis, trachoma, and Chagas disease. Washington (DC): Pan American Health Organization. License: CC BY-NC-SA 3.0 IGO. https://iris.paho.org/handle/10665.2/53312.
   Google Scholar
• Dahl MR, Thiel S, Matsushita M, Fujita T, Willis AC, Christensen T, Vorup-Jensen T, Jensenius JC. 2001 July. MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity. 15(1):127–35. doi:10.1016/s1074-7613(01)00161-3. PMID: 11485744.
   PubMed Web of Science ®Google Scholar
• Deban L, Jarva H, Lehtinen MJ, Bottazzi B, Bastone A, Doni A, Jokiranta TS, Mantovani A, Meri S. 2008 Dec 15. Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activation. J Immunol. 181(12):8433–40. doi:10.4049/jimmunol.181.12.8433. PMID: 19050261.
   PubMed Web of Science ®Google Scholar
• Dias JC, Ramos AN,sJr, Gontijo ED, Luquetti A, Shikanai-Yasuda MA, Coura JR, Torres RM, Melo JR, Almeida EA, Oliveira W,sJr, et al. 2016 Dec. Brazilian consensus on Chagas disease, 2015. Rev Soc Bras Med Trop. 49(Suppl 1):3–60. doi:10.1590/0037-8682-0505-2016. Erratum in: Rev Soc Bras Med Trop. 2017 Jan-Feb;50(1):149. PMID: 27982292.
   Google Scholar
• Diretrizes da Sociedade Brasileira de Diabetes: 2017-2018. 2017. Sociedade Brasileira de Diabetes; Organização: José Egidio, Paulo de Oliveira, Renan Magalhães Montenegro, Sérgio Vencio. São Paulo: Editora Clannad. p. 1–383. https://www.diabetes.org.br/profissionais/images/2017/diretrizes/diretrizes-sbd-2017-2018.pdf.
   Google Scholar
• Dobó J, Szakács D, Oroszlán G, Kortvely E, Kiss B, Boros E, Szász R, Závodszky P, Gál P, Pál G. 2016 Aug 18. MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked. Sci Rep. 6(1):31877. doi:10.1038/srep31877. PMID: 27535802; PMCID: PMC4989169.
   PubMedGoogle Scholar
• Evans-Osses I, de Messias-Reason I, Ramirez MI. 2013. The emerging role of complement lectin pathway in trypanosomatids: Molecular bases in activation, genetic deficiencies, susceptibility to infection, and complement system-based therapeutics. Sci World J. 2013:675898. doi:10.1155/2013/675898. Epub 2013 Feb 21. PMID: 23533355; PMCID: PMC3595680.
   Google Scholar
• Faludi AA, Izar MCO, Saraiva JFK, Chacra APM, Bianco HT, Afiune Neto A, et al. 2017. Atualização da Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose. Arq Bras Cardiol. 109(2, sup.1):1–91. doi:10.1016/S0140-6736(11)60739-3.09-2015-VYT-13-BR-J.
   Google Scholar
• Flores-Chavez MD, Sambri V, Schottstedt V, Higuera-Escalante FA, Roessler D, Chaves M, Laengin T, Martinez A, Fleischer B. 2018 Apr 25. Evaluation of the elecsys chagas assay for detection of trypanosoma cruzi-specific antibodies in a multicenter study in Europe and latin America. J Clin Microbiol. 56(5): e01446-17. doi:10.1128/JCM.01446-17. PMID: 29444836; PMCID: PMC5925710.
   PubMed Web of Science ®Google Scholar
• Garred P, Genster N, Pilely K, Bayarri-Olmos R, Rosbjerg A, Ma YJ, Skjoedt MO. 2016 Nov. A journey through the lectin pathway of complement-MBL and beyond. Immunol Rev. 274(1):74–97. doi:10.1111/imr.12468. PMID: 27782323.
   PubMed Web of Science ®Google Scholar
• Haapasalo K, Meri S. 2019 Aug 2. Regulation of the complement system by pentraxins. Front Immunol. 10:1750. doi:10.3389/fimmu.2019.01750. PMID: 31428091; PMCID: PMC6688104.
   PubMed Web of Science ®Google Scholar
• Hayashi M, Machida T, Ishida Y, Ogata Y, Omori T, Takasumi M, Endo Y, Suzuki T, Sekimata M, Homma Y, et al. 2019 Sep 15. Cutting edge: role of MASP-3 in the physiological activation of factor D of the alternative complement pathway. J Immunol. 203(6):1411–16. doi:10.4049/jimmunol.1900605. Epub 2019 Aug 9. PMID: 31399515.
   PubMed Web of Science ®Google Scholar
• Hertle E, Arts IC, van der Kallen CJ, Feskens EJ, Schalkwijk CG, Hoffmann-Petersen IT, Thiel S, Stehouwer CD, van Greevenbroek MM. 2016 June. Distinct longitudinal associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 with Endothelial dysfunction and intima-media thickness: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) study. Arterioscler Thromb Vasc Biol. 36(6):1278–85. doi:10.1161/ATVBAHA.115.306552. Epub 2016 Apr 7. PMID: 27055907.
   PubMed Web of Science ®Google Scholar
• Iwaki D, Kanno K, Takahashi M, Endo Y, Matsushita M, Fujita T. 2011 Oct 1. The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway. J Immunol. 187(7):3751–58. doi:10.4049/jimmunol.1100280. Epub 2011 Aug 24. PMID: 21865552.
   PubMed Web of Science ®Google Scholar
• Lambris JD, Ricklin D, Geisbrecht BV. 2008 Feb. Complement evasion by human pathogens. Nat Rev Microbiol. 6(2):132–42. doi:10.1038/nrmicro1824. PMID: 18197169; PMCID: PMC2814840.
   PubMed Web of Science ®Google Scholar
• Lidani KCF, Andrade FA, Bavia L, Damasceno FS, Beltrame MH, Messias-Reason IJ, Sandri TL. 2019 July 2. Chagas disease: from discovery to a Worldwide Health Problem. Front Public Health. 7:166. doi:10.3389/fpubh.2019.00166. PMID: 31312626; PMCID: PMC6614205.
   PubMed Web of Science ®Google Scholar
• Lidani KCF, Andrade FA, Beltrame MH, Chakravarti I, Tizzot MR, Cavalcanti EO, Sandri TL, Luz PR, Messias-Reason IJ. 2021 June. Ficolin-3 in chronic chagas disease: low serum levels associated with the risk of cardiac insufficiency. Parasite Immunol. 43(6):e12829. doi:10.1111/pim.12829. Epub 2021 Mar 18. PMID: 33686686.
   PubMed Web of Science ®Google Scholar
• Lidani KCF, Bavia L, Ambrosio AR, de Messias-Reason IJ. 2017 Apr 20. The complement system: a prey of Trypanosoma cruzi. Front Microbiol. 8:607. doi:10.3389/fmicb.2017.00607. PMID: 28473804; PMCID: PMC5397499.
   PubMed Web of Science ®Google Scholar
• Lidani KC, Beltrame MH, Luz PR, Sandri TL, Nisihara RM, de Messias-Reaso IJ. 2015. Is pentraxin 3 a cardiovascular marker in patients with chronic Chagas disease? Int J Cardiol. 190:233–35. doi:10.1016/j.ijcard.2015.04.106. Epub 2015 Apr 16. PMID: 25920034.
   PubMed Web of Science ®Google Scholar
• Lidani KCF, Sandri TL, Castillo-Neyra R, Andrade FA, Guimarães CM, Marques EN, Beltrame MH, Gilman RH, Messias-Reason IJ. 2020. Clinical and epidemiological aspects of chronic Chagas disease from Southern Brazil. J Braz Trop Med. 53:e20200225.
   PubMed Web of Science ®Google Scholar
• Luz PR, Boldt AB, Grisbach C, Kun JF, Velavan TP, Messias-Reason IJ. 2013 Apr 4. Association of L-ficolin levels and FCN2 genotypes with chronic chagas disease. PLoS One. 8(4):e60237. doi:10.1371/journal.pone.0060237. PMID: 23593180; PMCID: PMC3617223.
   PubMed Web of Science ®Google Scholar
• Luz PR, Miyazaki MI, Chiminacio Neto N, Padeski MC, Barros AC, Boldt AB, Messias-Reason IJ. 2016 Jan 8. Genetically determined MBL deficiency is associated with protection against Chronic Cardiomyopathy in Chagas Disease. PLoS Negl Trop Dis. 10(1):e0004257. doi:10.1371/journal.pntd.0004257. PMID: 26745156; PMCID: PMC4706301.
   PubMed Web of Science ®Google Scholar
• Luz PR, Miyazaki MI, Neto NC, Nisihara RM, Messias-Reason IJ. 2010 Sep 3. High levels of mannose-binding lectin are associated with the risk of severe cardiomyopathy in chronic Chagas Disease. Int J Cardiol. 143(3):448–50. doi:10.1016/j.ijcard.2009.09.467. Epub 2009 Oct 22. PMID: 19853314.
   PubMed Web of Science ®Google Scholar
• Nyholt DR. 2004 Apr. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet. 74(4):765–69. doi:10.1086/383251. Epub 2004 Mar 2. PMID: 14997420; PMCID: PMC1181954.
   PubMed Web of Science ®Google Scholar
• Oroszlán G, Kortvely E, Szakács D, Kocsis A, Dammeier S, Zeck A, Ueffing M, Závodszky P, Pál G, Gál P, et al. 2016 Jan 15. MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 is a potential activator: kinetic analysis involving specific MASP-1 and MASP-2 inhibitors. J Immunol. 196(2):857–65. doi:10.4049/jimmunol.1501717. Epub 2015 Dec 16. PMID: 26673137.
   PubMed Web of Science ®Google Scholar
• Pan American Health Organization. 2016. Neglected infectious diseases in the Americas: success stories and innovation to reach the neediest. https://iris.paho.org/handle/10665.2/31250.
   Google Scholar
• Rojas LZ, Glisic M, Pletsch-Borba L, Echeverría LE, Bramer WM, Bano A, Stringa N, Zaciragic A, Kraja B, Asllanaj E, et al. 2018 June 13. Electrocardiographic abnormalities in Chagas disease in the general population: a systematic review and meta-analysis. PLoS Negl Trop Dis. 12(6):e0006567. doi:10.1371/journal.pntd.0006567. PMID: 29897909; PMCID: PMC5999094.
   PubMed Web of Science ®Google Scholar
• Skjoedt MO, Palarasah Y, Munthe-Fog L, Jie Ma Y, Weiss G, Skjodt K, Koch C, Garred P. 2010 Nov. MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation. Immunobiology. 215(11):921–31. doi:10.1016/j.imbio.2009.10.006. Epub 2009 Nov 24. PMID: 19939495.
   PubMed Web of Science ®Google Scholar
• Vengen IT, Enger TB, Videm V, Garred P. 2017 Feb 20. Pentraxin 3, ficolin-2 and lectin pathway associated serine protease MASP-3 as early predictors of myocardial infarction - the HUNT2 study. Sci Rep. 7(1):43045. doi:10.1038/srep43045. PMID: 28216633; PMCID: PMC5316974.
   PubMedGoogle Scholar
• Weinschutz Mendes H, Boldt ABW, von Rosen Seeling Stahlke E, Jensenius JC, Thiel S, Messias-Reason IJT. 2020 Apr 2. Adding MASP1 to the lectin pathway-Leprosy association puzzle: hints from gene polymorphisms and protein levels. PLoS Negl Trop Dis. 14(4):e0007534. doi:10.1371/journal.pntd.0007534. PMID: 32240160; PMCID: PMC7162614.
   PubMed Web of Science ®Google Scholar
• [WHO] World Health Organization. Chagas disease (American trypanosomiasis) [Internet]. Geneva: WHO; 2019. [accessed 2021 Apr 15]: https://www.who.int/chagas/epidemiology/en/.
   Google Scholar
• Writing Group Members, Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Després JP, et al. 2016 Jan 26. Heart disease and stroke statistics-2016 update: a report from the American heart association. Circulation. 133(4):e38–360. doi:10.1161/CIR.0000000000000350. Epub 2015 Dec 16. Erratum in: Circulation. 2016 Apr 12;133(15):e599. PMID: 26673558.
   PubMed Web of Science ®Google Scholar
• Yancy CW, Jessup M, Bozkurt B, Butler J, Casey, DE,sJr, Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, et al. 2013 Oct 15. ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 62(16):e147–239. doi:10.1016/j.jacc.2013.05.019. Epub 2013 Jun 5. PMID: 23747642.
   PubMed Web of Science ®Google Scholar