Publication Cover
Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 52, 2023 - Issue 4
176
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Amphoteric Mannan as an Immune Response Modifier. New Model Immunobiologically Active Candida albicans Mannan-Based Formula

, , , , , & show all

References

  • Abbas AK. 2020. The surprising story of IL-2: from experimental models to clinical application. Am J Pathol. 190:1776–81. doi:10.1016/j.ajpath.2020.05.007.
  • Abdulamir AS, Hafidh RR, Abubaker F. 2010. In vitro immunogenic and immunostimulatory effects of zwitterionized 23-valent pneumococcal polysaccharide vaccine compared with nonzwitterionized vaccine. Curr Ther Res. 71:60–77. doi:10.1016/j.curtheres.2010.02.004.
  • Avci FY, Kasper DL. 2010. How bacterial carbohydrates influence the adaptive immune system. Annu Rev Immunol. 28:107–30. doi:10.1146/annurev-immunol-030409-101159.
  • Avci FY, Li X, Tsuji M, Kasper DL. 2011. A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design. Nat Med. 17:1602–09. doi:10.1038/nm.2535.
  • Bartheldyová E, Turánek Knotigová P, Zachová K, Mašek J, Kulich P, Effenberg R, Zyka D, Hubatka F, Kotouček J, Čelechovská H, et al. 2019. N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells. Carbohydr Polym. 207:521–32. doi:10.1016/j.carbpol.2018.10.121.
  • Berraondo P, Sanmamed MF, Ochoa MC, Etxeberria I, Aznar MA, Pérez-Gracia JL, Rodríguez-Ruiz ME, Ponz-Sarvise M, Castañón E, Melero I. 2019. Cytokines in clinical cancer immunotherapy. Br J Cancer. 120:6–15. doi:10.1038/s41416-018-0328-y.
  • Bystrický S, Paulovičová E, Machová E. 2003. Candida albicans mannan–protein conjugate as vaccine candidate. Immunol Lett. 85:251–55. doi:10.1016/S0165-2478(02)00241-9.
  • Cassone A, Boccanera M, Adriani D, Santoni G, De Bernardis F. 1995. Rats clearing a vaginal infection by Candida albicans acquire specific, antibody-mediated resistance to vaginal reinfection. Infect Immun. 63:2619–24. doi:10.1128/iai.63.7.2619-2624.1995.
  • Chávez-Galán L, Olleros ML, Vesin D, Garcia I. 2015. Much more than M1 and M2 macrophages, there are also CD169+ and TCR+ macrophages. Front Immunol. 6:263. doi:10.3389/fimmu.2015.00263.
  • Chin VK, Foong KJ, Maha A, Rusliza B, Norhafizah M, Chong PP. 2014. Early expression of local cytokines during systemic Candida albicans infection in a murine intravenous challenge model. Biomed Rep. 2:869–74. doi:10.3892/br.2014.365.
  • Čížová A, Bystrický P, Bystrický S. 2015. Ultrasonic and free-radical degradation of mannan from Candida albicans. Int J Biol Macromol. 75:32–36. doi:10.1016/j.ijbiomac.2014.12.046.
  • Čížová A, Csomorová K, Rychlý J, Bystrický S. 2019. Stability of cationic and amphoteric derivatives of mannan from the yeast Candida albicans. Carbohydr Polym. 207:440–46. doi:10.1016/j.carbpol.2018.11.101.
  • Čížová A, Neščáková Z, Malovíková A, Bystrický S. 2016. Preparation and characterization of cationic and amphoteric mannans from Candida albicans. Carbohydr Polym. 149:1–7. doi:10.1016/j.carbpol.2016.04.083.
  • Cobb BA, Kasper DL. 2005. Zwitterionic capsular polysaccharides: the new MHCII-dependent antigens. Cell Microbiol. 7:1398–403. doi:10.1111/j.1462-5822.2005.00591.x.
  • Conlon KC, Miljkovic MD, Waldmann TA. 2019. Cytokines in the treatment of cancer. J Interf Cytokine Res. 39:6–21. doi:10.1089/jir.2018.0019.
  • Dagan R, Poolman JT, Zepp F. 2008. Combination vaccines containing DTPa–Hib: impact of IPV and coadministration of CRM197 conjugates. Expert Rev Vaccines. 7:97–115. doi:10.1586/14760584.7.1.97.
  • Darwich L, Coma G, Peña R, Bellido R, Blanco EJJ, Este JA, Borras FE, Clotet B, Ruiz L, Rosell A, et al. 2009. Secretion of interferon-γ by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18. Immunology. 126:386–93. doi:10.1111/j.1365-2567.2008.02905.x.
  • Davidson L, van den Reek JMPA, Bruno M, van Hunsel F, Herings RMC, Matzaraki V, Boahen CK, Kumar V, Groenewoud HMM, van de Veerdonk FL, et al. 2022. Risk of candidiasis associated with interleukin-17 inhibitors: a real-world observational study of multiple independent sources. Lancet Reg Health Eur. 13:100266. doi:10.1016/j.lanepe.2021.100266.
  • Di X, Liang X, Shen C, Pei Y, Wu B, He Z. 2022. Carbohydrates used in polymeric systems for drug delivery: from structures to applications. Pharmaceutics. 14:739. doi:10.3390/pharmaceutics14040739.
  • dos Anjos Cassado A. 2017. F4/80 as a major macrophage marker: the case of the peritoneum and spleen. In: Kloc M, editor. Macrophages. Results and problems in cell differentiation. Vol. 62. Cham: Springer. p. 161–79. doi:10.1007/978-3-319-54090-0_7.
  • Erwig LP, Gow NAR. 2016. Interactions of fungal pathogens with phagocytes. Nat Rev Microbiol. 14:163–76. doi:10.1038/nrmicro.2015.21.
  • Gallorini S, Berti F, Parente P, Baronio R, Aprea S, D’Oro U, Pizza M, Telford JL, Wack A. 2007. Introduction of zwitterionic motifs into bacterial polysaccharides generates TLR2 agonists able to activate APCs. J Immunol. 179:8208–15. doi:10.4049/jimmunol.179.12.8208.
  • Gerritzen MJH, Martens DE, Wijffels RH, van der Pol L, Stork M. 2017. Bioengineering bacterial outer membrane vesicles as vaccine platform. Biotechnol Adv. 35:565–74. doi:10.1016/j.biotechadv.2017.05.003.
  • Gordon S, Hamann J, Lin H-H, Stacey M. 2011. F4/80 and the related adhesion-GPCRs. Eur J Immunol. 41:2472–76. doi:10.1002/eji.201141715.
  • Gow NAR, Latge JP, Munro CA. 2017. The fungal cell wall: structure, biosynthesis, and function. Fungal Kingdom. 267–92. doi:10.1128/9781555819583.ch12
  • Gozalbo D. 2014. Role of IFN-gamma in immune responses to Candida albicans infections. Front Biosci. 19:1279. doi:10.2741/4281.
  • Gupta A, Gupta R, Gupta G. 2009. Targeting cells for drug and gene delivery: emerging applications of mannans and mannan binding lectins. J Sci Ind Res. 68:465–83. http://nopr.niscpr.res.in/handle/123456789/4323
  • Han Y, Rhew KY. 2012. Comparison of two Candida mannan vaccines: the role of complement in protection against disseminated candidiasis. Arch Pharm Res. 35:2021–27. doi:10.1007/s12272-012-1120-9.
  • Han Y, Ulrich MA, Cutler JE. 1999. Candida albicans mannan extract–protein conjugates induce a protective immune response against experimental candidiasis. J Infect Dis. 179:1477–84. doi:10.1086/314779.
  • Harmer NJ, Chahwan R. 2016. Isotype switching: mouse IgG3 constant region drives increased affinity for polysaccharide antigens. Virulence. 7:623–26. doi:10.1080/21505594.2016.1193278.
  • Irache JM, Salman HH, Gamazo C, Espuelas S. 2008. Mannose-targeted systems for the delivery of therapeutics. Expert Opin Drug Deliv. 5:703–24. doi:10.1517/17425247.5.6.703.
  • Jones K, Savulescu AF, Brombacher F, Hadebe S. 2020. Immunoglobulin M in health and diseases: how far have we come and what next? Front Immunol. 11:595535. doi:10.3389/fimmu.2020.595535.
  • Jones JKN, Stoodley RJ. 1965. Fractionation using copper complexes. Methods Carbohydr Chem. 5:36–38.
  • Kong F, Ge L, Liu X, Huang N, Zhou F. 2012. Mannan-modified PLGA nanoparticles for targeted gene delivery. Int J Photoenergy. 2012:926754. doi:10.1155/2012/926754.
  • Kurosaki T, Kometani K, Ise W. 2015. Memory B cells. Nat Rev Immunol. 15:149–59. doi:10.1038/nri3802.
  • Li C, Kuemmerle J. 2021. Phenotypic alterations of macrophage contributes to extracellular matrix deposition in cultured macrophage RAW 264.7. Inflamm Bowel Dis. 27:S36–S36. doi:10.1093/ibd/izaa347.088.
  • List T, Neri D. 2013. Immunocytokines: a review of molecules in clinical development for cancer therapy. Clin Pharmacol Adv Appl. 29:29.
  • Machová E, Bystrický P, Malovíková A, Bystrický S. 2014. Preparation and characterization of carboxymethyl derivatives of yeast mannans in aqueous solutions. Carbohydr Polym. 110:219–23. doi:10.1016/j.carbpol.2014.03.079.
  • Machova E, Korcova J, Cizova A, Bystricky S. 2015. Inhibition of yeast growth by broadly cross-reactive antisera elicited by heterologous mannan-protein conjugate. J Microbiol Biotechnol. 25:1177–79. doi:10.4014/jmb.1410.10050.
  • Martinez FO, Helming L, Milde R, Varin A, Melgert BN, Draijer C, Thomas B, Fabbri M, Crawshaw A, Ho LP, et al. 2013. Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood. 121:e57–69. doi:10.1182/blood-2012-06-436212.
  • Meng Y, Kang M, Li D, Wang T, Kuang Z, Ma Y. 2020. Performance of a new Candida anti-mannan IgM and IgG assays in the diagnosis of candidemia. Rev Inst Med Trop Sao Paulo. 62:257–61. doi:10.1590/s1678-9946202062025.
  • Micoli F, Adamo R, Costantino P. 2018. Protein carriers for glycoconjugate vaccines: history, selection criteria, characterization and new trends. Molecules. 23:1451. doi:10.3390/molecules23061451.
  • Munder M, Mallo M, Eichmann K, Modolell M. 1998. Murine macrophages secrete interferon γ upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J Exp Med. 187:2103–08. doi:10.1084/jem.187.12.2103.
  • Netea MG, Brown GD, Kullberg BJ, Gow NAR. 2008. An integrated model of the recognition of Candida albicans by the innate immune system. Nat Rev Microbiol. 6:67–78. doi:10.1038/nrmicro1815.
  • Netea MG, Joosten LAB, Van Der Meer JWM, Kullberg BJ, Van De Veerdonk FL. 2015. Immune defence against Candida fungal infections. Nat Rev Immunol. 15:630–42. doi:10.1038/nri3897.
  • Nishat S, Andreana P. 2016. Entirely carbohydrate-based vaccines: an emerging field for specific and selective immune responses. Vaccines. 4:19. doi:10.3390/vaccines4020019.
  • Paulovičová L, Paulovičová E, Karelin AA, Tsvetkov YE, Nifantiev NE, Bystrický S. 2015a. Immune cell response to Candida cell wall mannan derived branched α-oligomannoside conjugates in mice. J Microbiol Immunol Infect. 48:9–19. doi:10.1016/j.jmii.2013.08.020.
  • Paulovičová E, Bujdáková H, Chupáčová J, Paulovičová L, Kertys P, Hrubiško M. 2015b. Humoral immune responses to Candida albicans complement receptor 3-related protein in the atopic subjects with vulvovaginal candidiasis. Novel sensitive marker for Candida infection. FEMS Yeast Res. 15:1–8. doi:10.1093/femsyr/fou001.
  • Paulovičová E, Machová E, Tulinská J, Bystrický S. 2007. Cell and antibody mediated immunity induced by vaccination with novel Candida dubliniensis mannan immunogenic conjugate. Int Immunopharmacol. 7:1325–33. doi:10.1016/j.intimp.2007.05.014.
  • Paulovičová L, Paulovičová E, Farkaš P, Čížová A, Bystrický P, Jančinová V, Turánek J, Pericolini E, Gabrielli E, Vecchiarelli A, et al. 2019a. Bioimmunological activities of Candida glabrata cellular mannan. FEMS Yeast Res. 19:19.
  • Paulovičová E, Paulovičová L, Farkaš P, Karelin AA, Tsvetkov YE, Krylov VB, Nifantiev NE. 2019b. Importance of Candida antigenic factors: structure-driven immunomodulation properties of synthetically prepared mannooligosaccharides in RAW264.7 macrophages. Front Cell Infect Microbiol. 9:378. doi:10.3389/fcimb.2019.00378.
  • Paulovičová L, Paulovičová E, Karelin AA, Tsvetkov YE, Nifantiev NE, Bystrický S. 2012. Humoral and cell-mediated immunity following vaccination with synthetic Candida cell wall mannan derived heptamannoside–protein conjugate. Int Immunopharmacol. 14:179–87. doi:10.1016/j.intimp.2012.07.004.
  • Pichichero ME. 2013. Protein carriers of conjugate vaccines: characteristics, development and clinical trials. Hum Vaccin Immunother. 9:2505–23. doi:10.4161/hv.26109.
  • Poulain D, Jouault T. 2004. Candida albicans cell wall glycans, host receptors and responses: elements for a decisive crosstalk. Curr Opin Microbiol. 7:342–49. doi:10.1016/j.mib.2004.06.011.
  • Rinaudo M, Hudry-Clergeon G. 1967. Étude des O-carboxyméthylcelluloses à degré de substitution variable. I: Préparation et caractérisation des produits. J Chim Phys. 64:1746–52.
  • Romani L. 2004. Immunity to fungal infections. Nat Rev Immunol. 4:11–23. doi:10.1038/nri1255.
  • Saraiva M, O’Garra A. 2010. The regulation of IL-10 production by immune cells. Nat Rev Immunol. 10:170–81. doi:10.1038/nri2711.
  • Sarazin A, Poulain D, Jouault T. 2010. In vitro pro- and anti-inflammatory responses to viable Candida albicans yeasts by a murine macrophage cell line. Med Mycol. 48:912–21. doi:10.3109/13693781003767592.
  • Seed PC. 2015. The human mycobiome. Cold Spring Harb Perspect Med. 5:a019810. doi:10.1101/cshperspect.a019810.
  • Shibata N, Suzuki A, Kobayashi H, Okawa Y. 2007. Chemical structure of the cell-wall mannan of Candida albicans serotype a and its difference in yeast and hyphal forms. Biochem J. 404:365–72. doi:10.1042/BJ20070081.
  • Shukla M, Chandley P, Rohatgi S. 2021. The role of B-cells and antibodies against Candida vaccine antigens in invasive candidiasis. Vaccines. 9:1159. doi:10.3390/vaccines9101159.
  • Sparber F, LeibundGut-Landmann S. 2019. Interleukin-17 in antifungal immunity. Pathogens. 8:54. doi:10.3390/pathogens8020054.
  • Sun L, Middleton DR, Wantuch PL, Ozdilek A, Avci FY. 2016. Carbohydrates as T-cell antigens with implications in health and disease. Glycobiology. 26:1029–40. doi:10.1093/glycob/cww062.
  • Taciak B, Białasek M, Braniewska A, Sas Z, Sawicka P, Kiraga Ł, Rygiel T, Król M. 2018. Evaluation of phenotypic and functional stability of RAW 264.7 cell line through serial passages. PLoS One. 13:e0198943. doi:10.1371/journal.pone.0198943.
  • Tiew PY, Mac Aogain M, Ali NABM, Thng KX, Goh K, Lau KJX, Chotirmall SH. 2020. The mycobiome in health and disease: emerging concepts, methodologies and challenges. Mycopathologia. 185:207–31.
  • Tiwari S. 2018. Mannosylated constructs as a platform for cell-specific delivery of bioactive agents. Crit Rev Ther Drug Carr Syst. 35:157–94. doi:10.1615/CritRevTherDrugCarrierSyst.2018020313.
  • Trautwein-Weidner K, Gladiator A, Nur S, Diethelm P, LeibundGut-Landmann S. 2015. IL-17-mediated antifungal defense in the oral mucosa is independent of neutrophils. Mucosal Immunol. 8:221–31. doi:10.1038/mi.2014.57.
  • Turner MD, Nedjai B, Hurst T, Pennington DJ. 2014. Cytokines and chemokines: at the crossroads of cell signalling and inflammatory disease. Biochim Biophys Acta Mol Cell Res. 1843:2563–82. doi:10.1016/j.bbamcr.2014.05.014.
  • Tzianabos A, Onderdonk A, Rosner B, Cisneros R, Kasper D. 1993. Structural features of polysaccharides that induce intra-abdominal abscesses. Science (80-). 262:416–19. doi:10.1126/science.8211161.
  • Vendele I, Willment JA, Silva LM, Palma AS, Chai W, Liu Y, Feizi T, Spyrou M, Stappers MHT, Brown GD, et al. 2020. Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls. PLoS Pathog. 16:1–29. doi:10.1371/journal.ppat.1007927.
  • Whibley N, Gaffen SL. 2014. Brothers in Arms: Th17 and Treg responses in Candida albicans immunity. PLoS Pathog. 10:e1004456. doi:10.1371/journal.ppat.1004456.
  • Woodward EA, Prêle CM, Nicholson SE, Kolesnik TB, Hart PH. 2010. The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1). Immunology. 131:118–27.
  • Xin H, Cartmell J, Bailey JJ, Dziadek S, Bundle DR, Cutler JE. 2012. Self-adjuvanting glycopeptide conjugate vaccine against disseminated candidiasis. PLoS One. 7:e35106. doi:10.1371/journal.pone.0035106.
  • Xin H, Cutler JE. 2011. Vaccine and monoclonal antibody that enhance mouse resistance to candidiasis. Clin Vaccine Immunol. 18:1656–67. doi:10.1128/CVI.05215-11.
  • Xin H, Dziadek S, Bundle DR, Cutler JE. 2008. Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against candidiasis. Proc Natl Acad Sci. 105:13526–31. doi:10.1073/pnas.0803195105.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.