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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 53, 2024 - Issue 4
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Research Articles

IL1RAP Exacerbates Sepsis-Induced Pulmonary and Spleen Injury Through Regulating CD4+ T Lymphocyte Differentiation

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References

  • Butcher, M. J., & Zhu, J. (2021). Recent advances in understanding the Th1/Th2 effector choice. Faculty reviews, 10, 30. https://doi.org/10.12703/r/10-30
  • Cabrera-Perez, J., Condotta, S. A., Badovinac, V. P., & Griffith, T. S. (2014). Impact of sepsis on CD4+ T cell immunity. Journal of Leukocyte Biology, 96(5), 767–777. https://doi.org/10.1189/jlb.5MR0114-067R
  • Cheng, P., Zhang, R., Shan, S., Yuan, B., Chen, J., Qiu, Z., & Du, Y. (2022). Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-κB signal pathways. Neuroscience Letters, 775, 136533. https://doi.org/10.1016/j.neulet.2022.136533
  • de Alcantara, CC, Reiche, E. M. V., & Simão, A. N. C. (2021). Cytokines in psoriasis. Advances in Clinical Chemistry, 100, 171–204. https://doi.org/10.1016/bs.acc.2020.04.004
  • De Boer, B., Sheveleva, S., Apelt, K., Vellenga, E., Mulder, A. B., Huls, G., & Jacob Schuringa, J. (2020). The IL1-IL1RAP axis plays an important role in the inflammatory leukemic niche that favors acute myeloid leukemia proliferation over normal hematopoiesis. Haematologica, 106(12), 3067–3078. https://doi.org/10.3324/haematol.2020.254987
  • Dinarello, C. A. (2018). Overview of the IL-1 family in innate inflammation and acquired immunity. Immunological Reviews, 281(1), 8–27. https://doi.org/10.1111/imr.12621
  • Dong, C. (2021). Cytokine regulation and function in T cells. Annual Review of Immunology, 39(1), 51–76. https://doi.org/10.1146/annurev-immunol-061020-053702
  • Frenay, J., Bellaye, P.S., Oudot, A., Helbling, A., Petitot, C., Ferrand, C., Collin, B., Dias, A. M. (2022). IL-1RAP, a key therapeutic target in cancer. International Journal of Molecular Sciences, 23(23). https://doi.org/10.3390/ijms232314918
  • George, J. A., Park, S. O., Choi, J. Y., Uyangaa, E., & Eo, S. K. (2020). Double-faced implication of CD4+ Foxp3+ regulatory T cells expanded by acute dengue infection via TLR2/MyD88 pathway. European Journal of Immunology, 50(7), 1000–1018. https://doi.org/10.1002/eji.201948420
  • Herremans, K. M., Szymkiewicz, D. D., Riner, A. N., Bohan, R.P., Tushoski, G.W., Davidson, A.M., Lou, X., Leong, M. C., Dean, B.D., Gerber, M., Underwood, P.W. (2022). The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma. Neoplasia, 28, 100789. https://doi.org/10.1016/j.neo.2022.100789
  • Hirahara, K., & Nakayama, T. (2016). CD4+ T-cell subsets in inflammatory diseases: Beyond the Th1/Th2 paradigm. International Immunology, 28(4), 163–171. https://doi.org/10.1093/intimm/dxw006
  • Huang, L., Wu, C., Xu, D., Cui, Y., & Tang, J. (2021). Screening of important factors in the early sepsis stage based on the evaluation of ssGSEA algorithm and ceRNA regulatory network. Evolutionary Bioinformatics, 17, 11769343211058463. https://doi.org/10.1177/11769343211058463
  • Huang, M., Cai, S., & Su, J. (2019). The pathogenesis of sepsis and potential therapeutic targets. International Journal of Molecular Sciences, 20(21), 5376. https://doi.org/10.3390/ijms20215376
  • Jaras, M., Johnels, P., Hansen, N., Ågerstam, H., Tsapogas, P., Rissler, M., Lassen, C., Olofsson, T., Bjerrum, O. W., Richter, J., & Fioretos, T. (2010). Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein. Proceedings of the National Academy of Sciences, 107(37), 16280–16285. https://doi.org/10.1073/pnas.1004408107
  • Li, J., Zhou, L., Li, Z., Yang, S., Tang, L., & Gong, H. (2021). Identification of crucial genes and infiltrating immune cells underlying sepsis-induced cardiomyopathy via weighted gene Co-expression network analysis. Frontiers in Genetics, 12, 812509. https://doi.org/10.3389/fgene.2021.812509
  • Liang, X., Guo, W., Ren, T., Huang, Y., Sun, K., Zhang, H., Yu, Y., Wang, W., & Niu, J. (2020). Macrophages reduce the sensitivity of osteosarcoma to neoadjuvant chemotherapy drugs by secreting interleukin-1 beta. Cancer Letters, 480, 4–14. https://doi.org/10.1016/j.canlet.2020.03.019
  • Liberg, D., Sime, W., Riva, M., Massoumi, R., Forsberg, G., & von Wachenfeldt, K. (2022). The CAN04 Antibody Targets IL1RAP and inhibits tumor growth in a PDX Model for NSCLC. https://cantargia.com/assets/uploads/Poster-PEGS-Europe-final.pdf
  • Lv, Q., Xia, Q., Li, A., & Wang, Z. (2021). The potential role of IL1RAP on tumor microenvironment-related inflammatory factors in stomach adenocarcinoma. Technology in Cancer Research & Treatment, 20, 5282. https://doi.org/10.1177/1533033821995282
  • Martin, M. D., Badovinac, V. P., & Griffith, T. S. (2020). CD4+ T cell responses and the sepsis-induced immunoparalysis state. Frontiers in Immunology, 11, 1364. https://doi.org/10.3389/fimmu.2020.01364
  • Md, F., T, B., & Ak, K. (2020). Sepsis and septic shock – basics of diagnosis, pathophysiology and clinical decision making. The Medical Clinics of North America, 104(4), 573–585. https://doi.org/10.1016/j.mcna.2020.02.011
  • Raphael, I., Rachel R,Joern, & Tg, F. (2020). Memory CD4+ T cells in immunity and autoimmune diseases. Cells, 9(3), 531. https://doi.org/10.3390/cells9030531
  • Shi, Y., Xu, H., Xiao, Y., Liu, P., Pang, P., Wu, S., Deng, L., & Chen, X. (2019). Gegen qinlian decoction downregulates the TLR7 signalling pathway to control influenza a virus infection. Biomed Pharmacother, 121, 109471. https://doi.org/10.1016/j.biopha.2019.109471
  • Snook, J. P., Kim, C., & Williams, M. A. (2018). TCR signal strength controls the differentiation of CD4+ effector and memory T cells. Sci Immunol, 3(25), eaas9103. https://doi.org/10.1126/sciimmunol.aas9103
  • Wang, W., Sung, N., Gilman-Sachs, A., & Kwak-Kim, J. (2020). T helper (th) cell profiles in pregnancy and recurrent pregnancy losses: Th1/Th2/Th9/Th17/Th22/Tfh cells. Frontiers in Immunology, 11, 2025. https://doi.org/10.3389/fimmu.2020.02025
  • Waśkiel-Burnat, A., Osińska, M., Salińska, A., Blicharz, L., Goldust, M., Olszewska, M., Rudnicka, L., (2021). The role of serum Th1, Th2, and Th17 cytokines in patients with Alopecia Areata: Clinical implications. Cells, 10(12), 3397. https://doi.org/10.3390/cells10123397
  • Yang, W., Chen, X., & Hu, H. (2020). CD4+ T-Cell Differentiation In Vitro. Methods molecular biology Clifton NJ, 2111, 91–99. https://doi.org/10.1007/978-1-0716-0266-9_8
  • Yang, X. W., Li, H., Feng, T., Zhang, W., Song, X.-R., Ma, C.-Y., Nie, M., Wang, L., Tan, X., Kang, Y., & Liao, X. (2022). Impairment of antigen-presenting function of peripheral γδ T cells in patients with sepsis. Clinical and Experimental Immunology, 207(1), 104–112. https://doi.org/10.1093/cei/uxab029
  • Zhang, Y., Chen, X., Wang, H., Gordon-Mitchell, S., Sahu, S., Bhagat, T. D., Choudhary, G., Aluri, S., Pradhan, K., Sahu, P., Carbajal, M., Zhang, H., Agarwal, B., Shastri, A., Martell, R., Starczynowski, D., Steidl, U., Maitra, A., & Verma, A. (2022). Innate immune mediator, interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer. Journal of Hematology & Oncology, 15(1), 70. https://doi.org/10.1186/s13045-022-01286-4
  • Zheng, K., Wu, S., Lv, Y., Pang, P., Deng, L., Xu, H., Shi, Y., & Chen, X. (2021). Carvacrol inhibits the excessive immune response induced by influenza virus A via suppressing viral replication and TLR/RLR pattern recognition. Journal of Ethnopharmacology, 268, 113555. https://doi.org/10.1016/j.jep.2020.113555
  • Zhou, M., Aziz, M., Ochani, M., Yang, W., Sharma, A., Wang, P. (2018). The protective role of human ghrelin in sepsis: Restoration of CD4+ T cell proliferation. PLoS One, 13(7), e0201139. https://doi.org/10.1371/journal.pone.0201139
  • Zhu, J. (2018). T helper cell differentiation, heterogeneity, and plasticity. Cold Spring Harbor Perspectives in Biology, 10(10), a030338. https://doi.org/10.1101/cshperspect.a030338

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