- J. Allison, H.M. Georgiou, A. Strasser, and D.L. Vaux, Transgenic expression of CD95 ligand on islet ß cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc. Natl. Acad. Sci. USA, 94: 3943-3947, 1997.
- K. Aoki, L.M. Akyurek, H. San, K. Leung, M.S. Parmacek, E.G. Nabel, and G.J. Nabel, Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy. Mol. Ther., 1: 555, 2000.
- K. Aoki, M. Kurooka, J.J. Chen, J. Petryniak, E.G. Nabel, and G.J. Nabel, Extracellular matrix interacts with soluble CD95L: Retention and enhancement of cytotoxicity. Nature Immunol., 24: 561, 2001.
- F. Batteux, P. Lore, D. Bucchini, and G. Chiocchia, Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis. J. Immunol., 164: 1681-1688, 2000.
- D. Bellgrau, D. Gold, H. Selawry, J. Moore, A. Franzusoff, and R.C. Duke, A role for CD95 ligand in preventing graft rejection. Nature, 377: 630-632, 1995.
- E. Bonfoco, P.M. Stuart, T. Brunner, T. Lin, T.S. Griffith, Y. Gao, H. Nakajima, P.A. Henkart, T.A. Ferguson, and D.R. Green, Inducible nonlymphoid Fas-ligand is responsible for superantigen-induced peripheral deletion of T-cells. Immunity, 9: 711, 1998.
- J.J. Chen, Y. Sun, and G.J. Nabel, Regulation of the proinflammatory effects of Fas ligand (CD95L). Science, 282: 1714-1717, 1998.
- W.J. Chen, M.E. Frank, W. Jin, and S.M. Wahl, TGF-ß released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity, 14: 715-725, 2001.
- W. Chen, W. Jin, H. Tian, P. Sicurello, M. Frank, J.M. Orenstein, and S.M. Wahl, Requirement for transforming growth factor betal in controlling T cell apoptosis. J. Exp. Med., 194: 439-453, 2001.
- J A. D'Alessio, A. Riccioli, P. Lauretti, F. Padula, B. Muciaccia, P. De Cesaris, A. Filippini, S. Nagata, and E. Ziparo, Testicular FasL is expressed by sperm cells. PNAS, 98: 3316, 2001.
- C. Deng, E. Goluszko, and P. Christadoss, Fas/Fas ligand pathway, apoptosis, and clonal anergy involved in systemic acetylcholine receptor T cell epitope tolerance. J. Immunol., 166: 3458-3467, 2001.
- T.A. Ferguson, S. Fletcher, J.M. Herndon, and T.S. Griffith, Neuropeptides modulate immune deviation induced via the anterior chamber of the eye. J. Immunol., 155: 1746-1756, 1995.
- T.A. Ferguson, J.M. Herndon, and P. Dube, The immune response and the eye. IV. A role for tumor necrosis factor in anterior chamber associated immune deviation. Invest. Ophthal. Vis. Sci., 35: 2643-2651, 1994.
- T.A. Ferguson, P. Hooper, S.M. Mahendra, and H.J. Kaplan, The wavelength of light governing intraocular immune reactions. Invest. Ophthaln. Vis. Sci., 33: 1788-1795, 1992.
- T.A. Ferguson and T.S. Griffith, A vision of cell death: Insights into immune privilege. Immunol. Rev., 156: 167-184, 1997.
- Y. Gao, J.M. Herndon, H. Zhang, T.S. Griffith, and T.A. Ferguson, Anti-inflammatory effects of CD95 ligand (FasL)-induced apoptosis. J. Exp. Med., 188: 887, 1998.
- C. Giordano, G. Stassi, R. De Maria, et al., Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science, 275: 960-963, 1997.
- B.R. Gochuico, K.M. Miranda, and E.M. Hessel, Airway epithelial Fas ligand expression: Potential role in modulating bronchial inflammation. Am. J. Physiol., 274: L444-L449, 1998.
- T.S. Griffith, T. Brunner, S.M. Fletcher, D.R. Green, and T.A. Ferguson, Fas ligand induced apoptosis as a mechanism of immune privilege. Science, 270: 1189-1192, 1995.
- T.S. Griffith, X. Yu, J.M. Herndon, D.R. Green, and T.A. Ferguson, CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunologic tolerance. Immunity, 5: 7-16, 1996.
- C. Gutierrez-Steil, T. Wrone-Smith, X. Sun, J.G. Krueger, T. Coven, and B.J. Nickoloff, Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L). J. Clin. Invest., 101: 33-39, 1998.
- L.L. Hill et al., A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet light. J. Exp. Med., 189: 1285-1293, 1999.
- A.M. Hohlbaum, S. Moe, and A. Marshak-Rothstein, Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival. J. Exp. Med., 191: 1200-1209, 2000.
- P. Hooper, N. Bora, H.J. Kaplan, and T.A. Ferguson, Inhibition of lymphocyte proliferation by resident ocular cells. Curr. Eye. Res., 10: 363-372, 1991.
- H. Hori, N. Joyce, and J.W. Streilein, Epithelium-deficient corneal allografts display immune privilege beneath the kidney capsule. Inves. Ophthalmol. Vis. Sci., 41: 443-452, 2000.
- M.S. Hu et al., Fas-FasL interaction involved in pathogenesis of ocular toxoplasmosis in mice. Infection and Immunity, 67: 928, 1999.
- J.S. Hunt et al., Fas ligand is positioned in the mouse uterus and placenta to prevent trafficking of Fas+ activated leukocytes between the mother and conceptus. J. Immunol., 158: 4122-4131, 1997.
- F.H. Igney, C.K. Behrens, and P.H. Krammer, Tumor counterattack-concept and reality. Eur. J. Immunol., 30: 725-731, 2000.
- M. Irmler et al., Inhibition of death receptor signals by cellular FLIP. Nature, 388: 190, 1997.
- C.-K. Joo, J.S. Pepose, and P.M. Stuart, T-cell mediated responses in a murine model of orthotopic corneal transplantation. Invest. Ophthalmol. Vis. Sci., 36: 1530-1540, 1995.
- A. Jorgensen et al., Human retinal pigment epithelial cell-induced apoptosis in activated T cells. Invest. Ophthalmol. Vis. Sci., 39: 1590, 1998.
- M. Kahn, H.J. Kaplan, and T.A. Ferguson, Retinal necrosis and immune response following anterior chamber inoculation of herpes simplex virus type-1 are regulated by light. Arch. Virol., 131: 115, 1993.
- S.M. Kang et al., Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nature Med., 3: 738-743, 1997.
- H. Kawashima, S. Yamagami, T. Tsuru, and D.S. Gregerson, Anterior chamber inoculation of splenocytes without Fas/Fas-ligand interaction primes for a delayed-type hypersensitivity response rather than inducing anterior chamber-associated immune deviation. Eur. J. Immunol., 27: 2490-2494, 1997.
- S.G. Kimmel et al., Murine xenogeneic immune responses to the human testis: A presumed immune-privileged tissue. Transplantation, 69: 1075-1084, 2000.
- C.M. Knudson and S.J. Korsmeyer, Bcl-2 and Bax function independently to regulate cell death. Nat. Genet., 16: 358-362, 1997.
- H. Lau et al., Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice. Science, 273: 109-112, 1996.
- X.C. Li, A.D. Wells, T.B. Strom, and L.A. Turka, The role of T cell apoptosis in transplantation tolerance. Cur. Opin. Immunol., 12: 522-527, 2000.
- X.K. Li et al., Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid. Transplantation, 66: 1416-1423, 1998.
- T. Lin et al., Fas ligand-mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease. J. Clin. Invest., 101: 570-577, 1998.
- I. Medana et al., Fas ligand (CD95L) protects neurons against perforin-mediated T lymphocyte cytotoxicity. J. Immunol. 167: 674-681, 2001.
- K. Miwa et al., Caspase 1-independent IL-1Bß release and inflammation induced by the apoptosis inducer Fas ligand. Nature Med., 4: 1287-1292, 1998.
- S. Nagata and P. Golstein, The Fas death factor. Science, 267: 1449-1456, 1995.
- J.Y. Niederkorn, The immune privilege of corneal allografts. Transplantation, 67: 1503-1508, 1999.
- C. Nishigori et al., Evidence that DNA damage triggers interleukin 10 cytokine production in UV-irradiated murine keratinocytes. Proc. Natl. Acad. Sci. USA, 93: 10354-10359, 1996.
- T. Okuyama et al., Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system. Gene. Ther., 5: 1047-1053, 1998.
- L. Otonello, G. Tortolina, M. Amelotti, and F. Dallegri, Soluble Fas ligand is che- motactic for human neutrophilic polymorphonuclear leukocytes. J. Immunol., 162: 3601-3606, 1999.
- K.A. Sabeklo, K.A. Kelly, M.H. Nahm, A.H. Cross, and J.H. Russell, Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system. J. Immunol., 159: 3096-3099, 1997.
- K.A. Sabelko-Downes, A.H. Cross, and J.H. Russell, Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis. J. Exp. Med., 189: 1195, 1999.
- A. Saitoh, T. Kawanabe, H.H. Weidong, N. Kayagaki, T. Kawamura, H. Yagita, K. Okumura, and S. Shimada, Selective upregulation of fibroblast Fas ligand expression, and prolongation of Fas/Fas ligand-mediated skin allograft survival, by retinoic acid: The skin as a retinoid-inducible immune privilege site. J. Invest. Dermatol., 115: 154-161, 2000.
- J M. Sata, H. Perlman, D.A. Muruve, M. Silver, M. Ikebe, T.A. Libermann, P. Oettgen, and K. Walsh, Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response. Proc. Natl. Acad. Sci. USA, 95: 1213-1217, 1998.
- M. Sata, Z. Luo, and K. Walsh, Fas ligand over expression on allograft en- dothelium inhibits inflammatory cell infiltration and transplant-associated intimai hyperplasia. J. Immunol., 166: 6964-6971, 2001.
- R.A. Schmid, U. Stammberger, S. Hillinger, A. Gaspert, C.H. Boasquevisque, U. Malipiero, A. Fontana, and W. Weder, Fas ligand gene transfer combined with low dose cyclosporine A reduces acute lung allograft rejection. Transplantation, 13 (Suppl 1): S324-S328, 2000.
- M. Schmizu et al., Fas/Apo-1 (CD95)-mediated apoptosis of neutrophils with Fas ligand (CD95L)-expressing tumors is crucial for induction of inflammation by neutrophilic polymorphonuclear leukocytes associated with antitumor immunity. Cell. Immunol. 207: 41, 2001.
- P.M. Stuart et al., CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J. Clin. Invest., 99: 396-402, 1997.
- T Suda et al., Expression of the Fas ligand in cell of T cell lineage. J. Immunol., 154: 3806-3813, 1995.
- G.C. Suvannavejh, M.C. Dal Cantro, L.A. Matis, and A.D. Miller, Fasmediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis. J. Clin. Invest., 105: 223-231, 2000.
- B. Thoma, M. Grell, K. Pfizenmaier, and P. Scheurich, Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses. J. Exp. Med., 172: 1019-1023, 1990.
- L. Tourneur, B. Malassagne, F. Batteux, M. Fabre, S. Mistou, E. Lallemand, P. Lores, and G. Chiocchia, Transgenic expression of CD95 ligand on thyroid folli-cular cells confers immune privilege upon thyroid allografts. J. Immunol., 167:1338-1346, 2001.
- S.E. Turvey et al., Fas ligand-transfected myoblasts and islet cell transplantation.Transplantation, 69: 1972-1976, 2000.
- M.R. Van den Brink et al., Fas ligand-deficient gld mice are more susceptible to graft-versus-host-disease. Transplantation, 70: 184-191, 2000.
- S. Yamagami et al., Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants. Transplantation, 64: 1107-1111, 1997.
- H.G. Zhang, M. Fleck, E.R. Kern, D. Liu, Y. Wang, H.C. Hsu, P. Yang, Z. Wang,D.T. Curiel, T. Zhou, and J.D. Mountz, Antigen presenting cells expressing Fas ligand down modulate chronic inflammatory disease in Fas ligand deficient mice.J. Clin. Invest., 105: 813-821, 2000.
- J. Zhang B. Ma, A. Marshak-Rothstein, and A. Fine, Characterization of a novel cis-element that regulates Fas ligand expression in corneal endothelial cells. J. Biol. Chem., 274: 26537-26542, 1999.
CELL DEATH AND IMMUNE PRIVILEGE
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.