Reactive Oxygen Species Independent Cytotoxicity Induced by Radiocontrast Agents in Tubular Cells (LLC-PK1 and MDCK)

REFERENCES

• Davidson CJ, Hlatky M, Morris KG, Pieper K, Skelton TN, Schwab SJ, Bashore TM. Cardiovascular and renal toxicity of a nonionic radiographic contrast agent after cardiac catheterization: a prospective trial. Ann Intern Med. 1989; 110: 119–124
   PubMed Web of Science ®Google Scholar
• Parfrey PS, Griffiths SM, Barrett BJ, Paul MD, Genge M, Withers J, Farid N, McManamon PJ. Contrast material-induced renal failure to patients with diabetes mellitus, renal insufficiency, or both: a prospective controlled study. N Engl J Med. 1989; 320: 143–149
   PubMed Web of Science ®Google Scholar
• Rudnick MR, Berns JS, Cohen RM, Goldfarb S. Contrast media associated nephrotoxicity. Semin Nephrol. 1997; 17: 15–26
   Google Scholar
• Waybill MM, Waybill PN. Contrast media-induced nephrotoxicity: identification of patients at risk and algorithms for prevention. Vasc Interv Radiol. 2001; 12: 3–9
   PubMed Web of Science ®Google Scholar
• Weisberg LS, Kurnik PB, Kurnik BR. Radiocontrast-induced nephropathy in humans: Role of vasoconstriction. Kidney Int. 1992; 41: 1408–1415
   PubMed Web of Science ®Google Scholar
• Tumlin JA, Wang A, Murray PT, Mathur VS. Fenoldopam mesylate blocks reductions in renal plasma flow after radiocontrast dye infusion: A pilot trial in the prevention of contrast nephropathy. Am Heart J. 2002; 143: 894–903
   PubMed Web of Science ®Google Scholar
• Wasaki M, Sugimoto J, Shirota K. Glucose alters the susceptibility of mesangial cells to contrast media. Invest Radiol. 2001; 7: 355–362
   Google Scholar
• Katholi RE, Woods WT Jr, Taylor GJ, Deitrick CL, Womack KA, Katholi CR, McCann WP. Oxygen free radicals and contrast nephropathy. Am J Kidney Dis. 1998; 32: 64–71
   PubMed Web of Science ®Google Scholar
• Agrawal M, Stouffer GA. Contrast induced nephrotoxicity after angiography. Am Med Sci. 2002; 323: 252–258
   PubMed Web of Science ®Google Scholar
• Murphy SW, Barrett BJ, Parfrey PS. Contrast nephropathy. J Am Soc Nephrol. 2000; 11: 177–182
   PubMed Web of Science ®Google Scholar
• Solomon R, Werner C, Mann D, D'Elia J, Silva P. Effects of saline, mannitol, and furosemide on acute decreases in renal function induced by radiocontrast agents. N Engl J Med. 1994; 331: 1416–1420
   PubMed Web of Science ®Google Scholar
• Trivedi HS, Moore H, Nasr S, Aggarwal K, Agrawal A, Goel P, Hewett J. A randomized prospective trial to assess the role of saline hydration on the development of contrast nephrotoxicity. Nephron Clin Pract. 2003; 93: C29–C34
   PubMed Web of Science ®Google Scholar
• Tepel M, van der Giet M, Schwarzfeld C, Laufer U, Liermann D, Zidek W. Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine. N Engl J Med. 2000; 343: 180–184
   PubMed Web of Science ®Google Scholar
• Drager LF, Andrade L, Barros de Toledo JF, Laurindo FR, Machado Cesar LA, Seguro AC. Renal effects of N-acetyl‐cysteine in patients at risk for contrast nephropathy: decrease in oxidant stress-mediated renal tubular injury. Nephrol Dial Transplant. 2004; 19: 1803–1807
   PubMedGoogle Scholar
• Hull RN, Cherry WR, Weaver GW. The origin and characteristics of a pig kidney cell strain, LLC-PK1. In Vitro. 1976; 12: 670
   PubMedGoogle Scholar
• American Type Culture Collection. Catalogue of Cell Lines and Hybridomas 7th, R Hay, M Mary, TR Chen, P McClintock, Y Reid. ATCC Press, Rockville, Md. 1992; 21
   Google Scholar
• Peuchant E, Delmas-Beauvieux MC, Duborg L, Thomas MJ, Peeromat A, Aparicio M, Clerc M, Combe C. Antioxidant effects of a supplemented very low protein diet in chronic renal failure. Free Radic Biol Med. 1997; 22: 131–320
   Google Scholar
• Rhoden E, Teloken C, Lucas M, Rhoden C, Mauri M, Zettler C, Bello-Klein A, Barros E. Protective effect of allopurinol in the renal ischemia-reperfusion in uninephrectomized rats. Gen Pharmacol. 2000; 35: 189–193
   PubMedGoogle Scholar
• Byer K, Khan SR. Citrate provides protection against oxalate and calcium oxalate crystal induced oxidative damage to renal epithelium. J Urol. 2005; 173: 640–646
   PubMed Web of Science ®Google Scholar
• Dinu D, Nechifor MT, Movileanu L. Ethanol-induced alterations of the antioxidant defense system in rat kidney. J Biochem Mol Toxicol. 2005; 19: 386–395
   Google Scholar
• Yang CC, Hsu SP, Wu MS, Chien CT. Effects of vitamin C infusion and vitamin E-coated membrane on hemodialysis-induced oxidative stress. Kidney Int. 2006; 69: 706–714
   PubMed Web of Science ®Google Scholar
• Zimmerhackl LB, Mesa H, Kraemer F, Koelmel C, Wiegele G, Brandis M. Tubular toxicity of cyclosporine A and the influence of endothelin-1 in renal cell culture model (LLC-PK1 and MDCK). Pediatr Nephrol. 1997; 11: 778–783
   Google Scholar
• Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis—flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Annexin V. J Immunol Methods. 1995; 184: 39–51
   PubMed Web of Science ®Google Scholar
• Ubezio P, Civoli F. Flow cytometric detection of hydrogen peroxide production induced by doxorubicin in cancer cells. Free Radic Biol Med. 1994; 16: 509–516
   PubMed Web of Science ®Google Scholar
• Hart MC, Tolson JK, Blocks ER. Supplemental fatty acids alter lipid peroxidation and oxidant injury in endothelial cells. Am J Physiol. 1991; 260: L481–L488
   PubMedGoogle Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar
• Beaufils H, Idee JM, Berthommier C, Balut C, Bourbouze R, Nimier K, Chicandre-Jouanneau C, Bonnemain B. Iobitridol, a new nonionic low-osmolality contrast agent, and iohexol: impact on renal histology in the rat. Invest Radiol. 1995; 30: 33–39
   PubMedGoogle Scholar
• Zager RA, Johnson ACM, Hanson SY. Radiographic contrast media-induced tubular injury: Evaluation of oxidant stress and plasma membrane integrity. Kidney Int. 2003; 64: 128–139
   PubMed Web of Science ®Google Scholar
• Hizoh I, Haller C. Radiocontrast-induced renal tubular cell apoptosis: hypertonic versus oxidative stress. Invest. Radiol. 2002; 37: 428–434
   PubMed Web of Science ®Google Scholar
• Sheridan AM, Schwartz JH, Kroshian VM, Tercyak AM, Laraia J, Masino S, Lieberthal W. Renal mouse proximal tubular cells are more susceptible than MDCK cells to chemical anoxia. Am. J. Physiol. 1993; 265: F342–F350
   PubMed Web of Science ®Google Scholar
• Fanning NF, Manning BJ, Buckley J, Redmond HP. Iodinated contrast media induces neutrophil apoptosis through a mitochondrial and caspase mediated pathway. Br J Radiol. 2002; 75: 861–873
   PubMed Web of Science ®Google Scholar
• Hardiek K, Katholi RE, Ramkumar V, Dietrick C. Proximal tubule cell response to radiographic contrast media. Am J Physiol Renal Physiol. 2001; 280: F61–F70
   PubMed Web of Science ®Google Scholar
• Schick SC, Haller C. Comparative cytotoxicity of ionic and non-ionic radiocontrast agents on MDCK cell monolayers in vitro. Nephrol Dial Transplant. 1999; 14: 342–347
   Google Scholar
• Qanungo S, Wang M, Nieminen AL. N-Acetyl-L-cysteine enhances apoptosis through inhibition of nuclear factor-kappaB in hypoxic murine embryonic fibroblasts. J Biol Chem. 2004; 279: 50455–50464
   PubMed Web of Science ®Google Scholar
• Holt S, Goodier D, Marley R, Patch D, Burroughs A, Fernando B, Harry D, Moore K. Improvement in renal function in hepatorenal syndrome with N-acetylcysteine. Lancet. 1999; 353: 294–295
   PubMed Web of Science ®Google Scholar
• Morley N, Curnow A, Salter L, Campbell S, Gould D. N-acetyl-L-cysteine prevents DNA damage induced by UVA, UVB and visible radiation in human fibroblasts. J. Photochem. Photobiol. B. 2003; 72: 55–60
   PubMed Web of Science ®Google Scholar
• Ricardo KF, Shishido SM, de Oliveira MG, Krieger MH. Characterization of the effect of S-nitroso-N-acetylcysteine in normotensive and hypertensive conscious rats. Nitric Oxide. 2002; 7: 57–66
   PubMed Web of Science ®Google Scholar
• Briguori C, Manganelli F, Scarpato P, Elia PP, Golia B, Riviezzo G, Lepore S, Librera M, Villari B, Colombo A, Ricciardelli B. Acetylcysteine and contrast agent-associated nephrotoxicity. J. Am. Coll. Cardiol. 2002; 40: 298–303
   PubMed Web of Science ®Google Scholar
• Allaqaband S, Tumuluri R, Malik AM, Gupta A, Volkert P, Shalev Y, Bajwa TK. Prospective randomized study of N-acetylcysteine, fenoldopam, and saline for prevention of radiocontrast-induced nephropathy. Catheter Cardiovasc. Interv. 2002; 57: 279–283
   PubMed Web of Science ®Google Scholar
• Durham JD, Caputo C, Dokko J, Zaharakis T, Pahlavan M, Keltz J, Dutka P, Marzo K, Maesaka JK, Fishbane S. A randomized controlled trial of N-acetylcysteine to prevent contrast nephropathy in cardiac angiography. Kidney Int. 2002; 62: 2202–2207
   PubMed Web of Science ®Google Scholar
• Gomes VO, Poli de Figueredo CE, Caramori P, Lasevitch R, Bodanese LC, Araujo A, Roedel AP, Caramori AP, Brito FS Jr, Bezerra HG, Nery P, Brizolara A. N-acetylcysteine does not prevent contrast induced nephropathy after cardiac catheterization with an ionic low osmolality contrast medium: a multicentre clinical trial. Heart. 2005; 91: 774–778
   PubMed Web of Science ®Google Scholar