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Clinical Studies

Effects of Immunosuppressive Drugs on Platelet Aggregation and Soluble P-Selectin Levels in Renal Transplant Patients

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Pages 111-117 | Received 25 Sep 2008, Accepted 04 Nov 2008, Published online: 07 Jul 2009

REFERENCES

  • Pham PT, Pham PC, Danovitch GM. Cardiovascular disease posttransplant. Semin Nephrol. 2007; 27(4)430–444
  • Sato K, Ogawa K, Onumata O, et al. Cause of death in renal transplant patients: A comparison between azathioprine and ciclosporin. Surg Today. 2001; 31: 681–687
  • Aker S, Ivens K, Grabensee B, Heering P. Cardiovascular risk factors and diseases after renal transplantation. Int Urol Nephrol. 1998; 30(4)777–788
  • Briggs JD. Causes of death after renal transplantation. Nephrol Dial Transplant. 2001; 16: 1545–1549
  • Ross R. The pathogenesis of atherosclerosis: An update. N Engl J Med. 1986; 314: 488–500
  • Vanrenterghem Y, Roels L, Lerut T, et al. Tromboembolic complications and haemostatic changes in cyclosporine-treated cadaveric kidney allograft recipients. Lancet. 1985; 1: 999–1002
  • Grace AA, Barradas MA, Mikhailidis DP, Jeremy JY, Sweny P, Dandona P. Cyclosporine A enhaces platelet aggregation. Kidney Int. 1987; 32(6)889–895
  • Malyszko J, Malyszko JS, Takada A, Mysliwiec M. Effects of immunosuppressive drugs platelet aggregation in vivo. Ann Transplant. 2002; 7(1)55–68
  • Graff J, Klinkhardt U, Harder S, et al. Immunosuppressive therapy regimen and platelet activation in renal transplant patients. Clin Pharmacol Ther. 2002; 72(4)411–418
  • Malyszko J, Malyszko JS, Pawlak K, Michal M. The coagulo-lytic system and endothelial function in cyclosporine-treated kidney allograft recipients. Transplantation. 1996; 62(2)828–830
  • Verpooten GA, Cools FJ, Van der Planken MG, et al. Elevated plasminogen activator inhibitor levels in cyclosporine-treated renal allograft recipients. Nephrol Dial Transplant. 1996; 11: 347–351
  • Opelz G, Wujciak T, Ritz E, et al. Association of chronic kidney graft failure with recipient blood pressure. Kidney Int. 1998; 53: 217–222
  • Canzanello VJ, Schwartz L, Tater SJ, et al. Evolution of cardiovascular risk after liver transplantation: A comparison of cyclosporine A and tacrolimus FK(506). Liver Transpl Surg. 1997; 3: 1–9
  • Grace AA, Barradas MA, Mikhailidis DP, et al. Cyclosporine A enhances platelet aggregation. Kidney Int. 1987; 32(6)889–895
  • Fernandes JB, Naik UP, Markell MS, Kornecki E. Comparative investigation of the effects of the immunusuppresants cyclosporine A, cyclosporine G, and FK-506 on platelet aggregation. Cell Mol Biol Res. 1993; 39(3)265–274
  • Klein BC, Bach D, Rehfeld I, et al. Influence of mycophenolic acid and FK-506 on human platelet activation in vitro. Kidney Blood Press Res. 2000; 23(2)119–124
  • Blann AD, Lip GY. Hypothesis: Is soluble P-selectin a new marker of platelet activation?. Atherosclerosis. 1997; 128: 135–138
  • Andre P, Hartwell D, Hrachovinova I, Saffaripour S, Wagner DD. Pro-coagulant state resulting from high levels of P-selectin in blood. Proc Natl Acad Sci USA. 2000; 97: 13835–13840
  • Blann AD, Fargher EB, McCollum CN. Increased soluble P-selecyn in ischaemic heart disease: A new marker for the progression of atherosclerosis. Blood Coagul Fibrinolys. 1997; 8: 383–390
  • Ridker PM, Buring JE, Rifai N. Soluble P-selectin and the risk of future cardiovascular events. Circulation. 2001; 103: 491–495
  • Hillis GS, Terregino C, Taggart P, Killian A, Zhao N, Dalsey WC. Elevated soluble P-selectin levels are associated with an increased risk of early adverse in patients with presumed myocardial infarction. Am Heart J. 2002; 143: 235–241

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