Long–term mortality after parathyroidectomy among chronic kidney disease patients with secondary hyperparathyroidism: a systematic review and meta-analysis

References

• Levey AS, Coresh J. Chronic kidney disease. Lancet. 2012;379:165–180.
   PubMed Web of Science ®Google Scholar
• Cunningham J, Locatelli F, Rodriguez M. Secondary hyperparathyroidism: Pathogenesis, disease progression, and therapeutic options. Clin J Am Soc Nephrol. 2011;6:913–921.
   PubMed Web of Science ®Google Scholar
• Liabeuf S, Desjardins L, Diouf M, et al. The addition of vascular calcification scores to traditional risk factors improves cardiovascular risk assessment in patients with chronic kidney disease. PLoS One. 2015;10:e0131707–26181592.
   Web of Science ®Google Scholar
• Felsenfeld AJ, Levine BS, Rodriguez M. Pathophysiology of calcium, phosphorus, and magnesium dysregulation in chronic kidney disease. Semin Dial. 2015;28:564–577.
   PubMed Web of Science ®Google Scholar
• Shanahan CM. Mechanisms of vascular calcification in CKD-evidence for premature ageing. Nat Rev Nephrol. 2013;9:661–670.
   PubMed Web of Science ®Google Scholar
• Chertow GM, Correa-Rotter R, Block GA, et al. Baseline characteristics of subjects enrolled in the Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) trial. Nephrol Dial Transplant. 2012;27:2872–2879.
   PubMed Web of Science ®Google Scholar
• Ganesh SK, Stack AG, Levin NW, Hulbert-Shearon T, Port FK. Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol. 2001;12:2131–2138.
   PubMed Web of Science ®Google Scholar
• Avram MM, Mittman N, Myint MM, Fein P. Importance of low serum intact parathyroid hormone as a predictor of mortality in hemodialysis and peritoneal dialysis patients: 14 years of prospective observation. Am J Kidney Dis. 2001;38:1351–1357.
   PubMed Web of Science ®Google Scholar
• Fukagawa M, Komaba H, Kakuta T. Hyperparathyroidism in chronic kidney disease patients: An update on current pharmacotherapy. Expert Opin Pharmacother. 2013;14:863–871.
   PubMed Web of Science ®Google Scholar
• Ghani A, Baxter P. Surgical parathyroidectomy versus cinacalcet therapy: in the management of secondary hyperparathyroidism. Otolaryngol Head Neck Surg. 2012;146:220–225.
   PubMed Web of Science ®Google Scholar
• Chertow GM, Block GA, Correa-Rotter R, et al. Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis. N Engl J Med. 2012;367:2482–2494.
   PubMed Web of Science ®Google Scholar
• Palmer SC, Teixeira-Pinto A, Saglimbene V, et al. Association of drug effects on serum parathyroid hormone, phosphorus, and calcium levels with mortality in CKD: A meta-analysis. Am J Kidney Dis. 2015;66:962–971.
   PubMed Web of Science ®Google Scholar
• Parfrey PS, Drueke TB, Block GA, et al. The effects of cinacalcet in older and younger patients on hemodialysis: The evaluation of cinacalcet HCl therapy to lower cardiovascular events (EVOLVE) trial. Clin J Am Soc Nephrol. 2015;10:791–799.
   PubMed Web of Science ®Google Scholar
• Ballinger AE, Palmer SC, Nistor I, Craig JC, Strippoli GF. Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients. Cochrane Database Syst Rev. 2014;12:CD006254.
   PubMed Web of Science ®Google Scholar
• Lorenz K, Bartsch DK, Sancho JJ, Guigard S, Triponez F. Surgical management of secondary hyperparathyroidism in chronic kidney disease-a consensus report of the European society of endocrine surgeons. Langenbecks Arch Surg. 2015;400:907–927.
   PubMed Web of Science ®Google Scholar
• Yuan CM, Nee R, Narayan R, Abbott KC. Treatment of secondary hyperparathyroidism with parathyroidectomy instead of cinacalcet: time to pick the low-hanging fruit. Am J Kidney Dis. 2012;60:179–181.
   PubMed Web of Science ®Google Scholar
• Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: A proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA. 2000;283:2008–2012.
   PubMed Web of Science ®Google Scholar
• Gu WJ, Wang F, Tang L, Liu JC. Single-dose etomidate does not increase mortality in patients with sepsis: A systematic review and meta-analysis of randomized controlled trials and observational studies. Chest. 2015;147:335–346.
   PubMed Web of Science ®Google Scholar
• Costa-Hong V, Jorgetti V, Gowdak LH, Moyses RM, Krieger EM, De Lima JJ. Parathyroidectomy reduces cardiovascular events and mortality in renal hyperparathyroidism. Surgery. 2007;142:699–703.
   PubMed Web of Science ®Google Scholar
• Sharma J, Raggi P, Kutner N, et al. Improved long-term survival of dialysis patients after near-total parathyroidectomy. J Am Coll Surg. 2012;214:400–407.
   PubMed Web of Science ®Google Scholar
• Dussol B, Morand P, Martinat C, et al. Influence of parathyroidectomy on mortality in hemodialysis patients: A prospective observational study. Ren Fail. 2007;29:579–586.
   PubMed Web of Science ®Google Scholar
• Goldenstein PT, Elias RM, de Freitas do Carmo LP, et al. Parathyroidectomy improves survival in patients with severe hyperparathyroidism: A comparative study. PLoS One. 2013;8:e68870.
   PubMed Web of Science ®Google Scholar
• Iwamoto N, Sato N, Nishida M, et al. Total parathyroidectomy improves survival of hemodialysis patients with secondary hyperparathyroidism. J Nephrol. 2012;25:755–763.
   PubMed Web of Science ®Google Scholar
• Kestenbaum B, Andress DL, Schwartz SM, et al. Survival following parathyroidectomy among United States dialysis patients. Kidney Int. 2004;66:2010–2016.
   PubMed Web of Science ®Google Scholar
• Ivarsson KM, Akaberi S, Isaksson E, et al. The effect of parathyroidectomy on patient survival in secondary hyperparathyroidism. Nephrol Dial Transplant. 2015;30:2027–2033.
   PubMed Web of Science ®Google Scholar
• Komaba H, Taniguchi M, Wada A, Iseki K, Tsubakihara Y, Fukagawa M. Parathyroidectomy and survival among Japanese hemodialysis patients with secondary hyperparathyroidism. Kidney Int. 2015;88:350–359.
   PubMed Web of Science ®Google Scholar
• Trombetti A, Stoermann C, Robert JH, et al. Survival after parathyroidectomy in patients with end-stage renal disease and severe hyperparathyroidism. World J Surg. 2007;31:1014–1021.
   PubMed Web of Science ®Google Scholar
• Ma TL, Hung PH, Jong IC, et al. Parathyroidectomy is associated with reduced mortality in hemodialysis patients with secondary hyperparathyroidism. Biomed Res Int. 2015;2015:639587.
   PubMedGoogle Scholar
• Li W, Zhang M, Du S, et al. Impact of parathyroidectomy on survival among hemodialysis patients: A prospective cohort study. Nephrology (Carlton). 2016;21:133–138.
   Web of Science ®Google Scholar
• Conzo G, Perna AF, Savica V, et al. Impact of parathyroidectomy on cardiovascular outcomes and survival in chronic hemodialysis patients with secondary hyperparathyroidism. A retrospective study of 50 cases prior to the calcimimetics era. BMC Surg. 2013;13:S4–S24268127.
   PubMed Web of Science ®Google Scholar
• Moldovan D, Racasan S, Kacso IM, et al. Survival after parathyroidectomy in chronic hemodialysis patients with severe secondary hyperparathyroidism. Int Urol Nephrol. 2015;47:1871–1877.
   PubMed Web of Science ®Google Scholar
• Tentori F, Wang M, Bieber BA, et al. Recent changes in therapeutic approaches and association with outcomes among patients with secondary hyperparathyroidism on chronic hemodialysis: the DOPPS study. Clin J Am Soc Nephrol. 2015;10:98–109.
   PubMed Web of Science ®Google Scholar
• Zhang YB, Smogorzewski M, Ni Z, Massry SG. Altered cytosolic calcium homeostasis in rat cardiac myocytes in CRF. Kidney Int. 1994;45:1113–1119.
   PubMed Web of Science ®Google Scholar
• Amann K, Ritz E, Wiest G, Klaus G, Mall G. A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia. J Am Soc Nephrol. 1994;4:1814–1819.
   PubMed Web of Science ®Google Scholar
• Rashid G, Bernheim J, Green J, Benchetrit S. Parathyroid hormone stimulates the endothelial nitric oxide synthase through protein kinase A and C pathways. Nephrol Dial Transplant. 2007;22:2831–2837.
   PubMed Web of Science ®Google Scholar
• Raggi P, Boulay A, Chasan-Taber S, et al. Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease. J Am Coll Cardiol. 2002;39:695–701.
   PubMed Web of Science ®Google Scholar
• Soares AA, Freitas WM, Japiassu AV, et al. Enhanced parathyroid hormone levels are associated with left ventricle hypertrophy in very elderly men and women. J Am Soc Hypertens. 2015;9:697–704.
   PubMed Web of Science ®Google Scholar
• Leibowitz D. Left ventricular hypertrophy and chronic renal insufficiency in the elderly. Cardiorenal Med. 2014;4:168–175.
   PubMed Web of Science ®Google Scholar
• Hamano T, Matsui I, Mikami S, et al. Fetuin-mineral complex reflects extraosseous calcification stress in CKD. J Am Soc Nephrol. 2010;21:1998–2007.
   PubMed Web of Science ®Google Scholar
• Goto N, Tominaga Y, Matsuoka S, et al. Cardiovascular complications caused by advanced secondary hyperparathyroidism in chronic dialysis patients; special focus on dilated cardiomyopathy. Clin Exp Nephrol. 2005;9:138–141.
   PubMedGoogle Scholar
• Rudser KD, de Boer IH, Dooley A, Young B, Kestenbaum B. Fracture risk after parathyroidectomy among chronic hemodialysis patients. J Am Soc Nephrol. 2007;18:2401–2407.
   PubMed Web of Science ®Google Scholar
• Coen G, Calabria S, Bellinghieri G, et al. Parathyroidectomy in chronic renal failure: short- and long-term results on parathyroid function, blood pressure and anemia. Nephron. 2001;88:149–155.
   PubMed Web of Science ®Google Scholar
• Zhang J, Yu X, Sun B, et al. Parathyroidectomy and heart rate variability in patients with stage 5 CKD. Clin J Am Soc Nephrol. 2013;8:1378–1387.
   PubMed Web of Science ®Google Scholar
• Girotto JA, Harmon JW, Ratner LE, Nicol TL, Wong L, Chen H. Parathyroidectomy promotes wound healing and prolongs survival in patients with calciphylaxis from secondary hyperparathyroidism. Surgery. 2001;130:645–650.
   PubMed Web of Science ®Google Scholar
• Yasunaga C, Nakamoto M, Matsuo K, Nishihara G, Yoshida T, Goya T. Effects of a parathyroidectomy on the immune system and nutritional condition in chronic dialysis patients with secondary hyperparathyroidism. Am J Surg. 1999;178:332–336.
   PubMed Web of Science ®Google Scholar
• Chou FF, Lee CH, Lee CT. Muscle force and bone mineral density after parathyroidectomy and subcutaneous autotransplantation for secondary hyperparathyroidism. World J Surg. 1999;23:452–456. discussion 456–457.
   PubMed Web of Science ®Google Scholar
• Faul C, Amaral AP, Oskouei B, et al. FGF23 induces left ventricular hypertrophy. J Clin Invest. 2011;121:4393–4408.
   PubMed Web of Science ®Google Scholar
• Ishani A, Liu J, Wetmore JB, et al. Clinical outcomes after parathyroidectomy in a nationwide cohort of patients on hemodialysis. Clin J Am Soc Nephrol. 2015;10:90–97.
   PubMed Web of Science ®Google Scholar
• Tominaga Y, Matsuoka S, Uno N, Sato T. Parathyroidectomy for secondary hyperparathyroidism in the era of calcimimetics. Ther Apher Dial. 2008;12:S21–S26.
   PubMed Web of Science ®Google Scholar
• Tominaga Y. Basic and clinical aspects of calcimimetics. Calcimimetic is indicated for patients with surgically uncontrollable hyperparathyroidism. Clin Calcium. 2008;18:67–71.
   PubMedGoogle Scholar
• Rodríguez M, Goodman WG, Liakopoulos V, Messa P, Wiecek A, Cunningham J. The use of calcimimetics for the treatment of secondary hyperparathyroidism: A 10 year evidence review. Semin Dial. 2015;28:497–507.
   PubMed Web of Science ®Google Scholar
• Chen J, Zhou QY, Wang JD. Comparison between subtotal parathyroidectomy and total parathyroidectomy with autotransplantation for secondary hyperparathyroidism in patients with chronic renal failure: A meta-analysis. Horm Metab Res. 2015;47:643–651.
   PubMed Web of Science ®Google Scholar
• Jia X, Wang R, Zhang C, Cui M, Xu D. Long-term outcomes of total parathyroidectomy with or without autoimplantation for hyperparathyroidism in chronic kidney disease: A meta-analysis. Ther Apher Dial. 2015;19:477–485.
   PubMed Web of Science ®Google Scholar