Kidney injury molecule-1 in kidney disease

References

• National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Am J Kidney Dis. 2002;39:S1–S266.
   PubMed Web of Science ®Google Scholar
• Shao X, Tian L, Xu W, et al. Diagnostic value of urinary kidney injury molecule 1 for acute kidney injury: A meta-analysis. PLoS One. 2014;9:e84131.
   PubMed Web of Science ®Google Scholar
• Vaidya VS, Ferguson MA, Bonventre JV. Biomarkers of acute kidney injury. Annu Rev Pharmacol Toxicol. 2008;48:463–493.
   PubMed Web of Science ®Google Scholar
• Rees AJ, Kain R. Kim-1/Tim-1: From biomarker to therapeutic target? Nephrol Dial Transplant. 2008;23:3394–3396.
   PubMed Web of Science ®Google Scholar
• Ichimura T, Bonventre JV, Bailly V, et al. Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem. 1998;273:4135–4142.
   PubMed Web of Science ®Google Scholar
• Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV. Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem. 2002;277:39739–39748.
   PubMed Web of Science ®Google Scholar
• Kaplan G, Totsuka A, Thompson P, Akatsuka T, Moritsugu Y, Feinstone SM. Identification of a surface glycoprotein on African green monkey kidney cells as a receptor for hepatitis A virus. EMBO J. 1996;15:4282–4296.
   PubMed Web of Science ®Google Scholar
• Silberstein E, Dveksler G, Kaplan GG. Neutralization of hepatitis A virus (HAV) by an immunoadhesin containing the cysteine-rich region of HAV cellular receptor-1. J Virol. 2001;75:717–725.
   PubMed Web of Science ®Google Scholar
• Tami C, Silberstein E, Manangeeswaran M, et al. Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 2007;81:3437–3446.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Manzanet R, DeKruyff R, Kuchroo VK, Umetsu DT. The costimulatory role of TIM molecules. Immunol Rev. 2009;229:259–270.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Humphreys BD, Bonventre JV. Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region. J Am Soc Nephrol. 2007;18:2704–2714.
   PubMed Web of Science ®Google Scholar
• Sabbisetti VS, Ito K, Wang C, Yang L, Mefferd SC, Bonventre JV. Novel assays for detection of urinary KIM-1 in mouse models of kidney injury. Toxicol Sci. 2013;131:13–25.
   PubMed Web of Science ®Google Scholar
• Sabbisetti VS, Waikar SS, Antoine DJ, et al. Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes. J Am Soc Nephrol. 2014;25:2177–2186.
   PubMed Web of Science ®Google Scholar
• van de Vrie M, Deegens JK, van der Vlag J, Hilbrands LB. Effect of long-term storage of urine samples on measurement of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL). Am J Kidney Dis. 2014;63:573–576.
   PubMed Web of Science ®Google Scholar
• Pennemans V, Rigo JM, Penders J, Swennen Q. Collection and storage requirements for urinary kidney injury molecule-1 (KIM-1) measurements in humans. Clin Chem Lab Med. 2012;50:539–543.
   Web of Science ®Google Scholar
• Waanders F, van Timmeren MM, Stegeman CA, Bakker SJ, van Goor H. Kidney injury molecule-1 in renal disease. J Pathol. 2010;220:7–16.
   PubMed Web of Science ®Google Scholar
• Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest. 2008;118:1657–1668.
   PubMed Web of Science ®Google Scholar
• Gandhi R, Yi J, Ha J, et al. Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis. Am J Physiol Renal Physiol. 2014;307:F205–F221.
   Google Scholar
• van Timmeren MM, van den Heuvel MC, Bailly V, Bakker SJ, van Goor H, Stegeman CA. Tubular kidney injury molecule-1 (KIM-1) in human renal disease. J Pathol. 2007;212:209–217.
   PubMed Web of Science ®Google Scholar
• Kramer AB, van Timmeren MM, Schuurs TA, et al. Reduction of proteinuria in Adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol. 2009;296:F1136–F1145.
   PubMed Web of Science ®Google Scholar
• Kuehn EW, Park KM, Somlo S, Bonventre JV. Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol. 2002;283:F1326–F1336.
   PubMed Web of Science ®Google Scholar
• Han WK, Alinani A, Wu CL, et al. Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma. J Am Soc Nephrol. 2005;16:1126–1134.
   PubMed Web of Science ®Google Scholar
• Pennemans V, Rigo JM, Faes C, Reynders C, Penders J, Swennen Q. Establishment of reference values for novel urinary biomarkers for renal damage in the healthy population: Are age and gender an issue? Clin Chem Lab Med. 2013;51:1795–1802.
   PubMed Web of Science ®Google Scholar
• McWilliam SJ, Antoine DJ, Sabbisetti V, et al. Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children. Biomark Med. 2014;8:1189–1197.
   PubMed Web of Science ®Google Scholar
• Zwiers AJ, de Wildt SN, de Rijke YB, et al. Reference intervals for renal injury biomarkers neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in young infants. Clin Chem Lab Med. 2015;53:1279–1289.
   PubMed Web of Science ®Google Scholar
• James M, Bouchard J, Ho J, et al. Canadian Society of nephrology commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury. Am J Kidney Dis. 2013;61:673–685.
   PubMed Web of Science ®Google Scholar
• Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for kidney injury biomarker evaluation. J Am Soc Nephrol. 2012;23:13–21.
   PubMed Web of Science ®Google Scholar
• Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. 2002;62:237–244.
   PubMed Web of Science ®Google Scholar
• Yu W, Beaudry S, Negoro H, et al. H2O2 activates G protein, α 12 to disrupt the junctional complex and enhance ischemia reperfusion injury. Proc Natl Acad Sci U S A. 2012;109:6680–6685.
   PubMed Web of Science ®Google Scholar
• Dhanasekaran N, Dermott JM. Signaling by the G12 class of G proteins. Cell Signal. 1996;8:235–245.
   PubMed Web of Science ®Google Scholar
• Ismail OZ, Zhang X, Wei J, et al. Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury. Am J Pathol. 2015;185:1207–1215.
   PubMed Web of Science ®Google Scholar
• Ko GJ, Grigoryev DN, Linfert D, et al. Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition. Am J Physiol Renal Physiol. 2010;298:F1472–F1483.
   PubMed Web of Science ®Google Scholar
• Humphreys BD, Xu F, Sabbisetti V, et al. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest. 2013;123:4023–4035.
   PubMed Web of Science ®Google Scholar
• Bonventre JV. Kidney injury molecule-1 (KIM-1): A urinary biomarker and much more. Nephrol Dial Transplant. 2009;24:3265–3268.
   PubMed Web of Science ®Google Scholar
• Luo QH, Chen ML, Sun FJ, et al. KIM-1 and NGAL as biomarkers of nephrotoxicity induced by gentamicin in rats. Mol Cell Biochem. 2014;397:53–60.
   PubMed Web of Science ®Google Scholar
• van Timmeren MM, Vaidya VS, van Ree RM, et al. High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients. Transplantation. 2007;84:1625–1630.
   PubMed Web of Science ®Google Scholar
• Peters HP, Waanders F, Meijer E, et al. High urinary excretion of kidney injury molecule-1 is an independent predictor of end-stage renal disease in patients with IgA nephropathy. Nephrol Dial Transplant. 2011;26:3581–3588.
   PubMed Web of Science ®Google Scholar
• Lin Q, Chen Y, Lv J, et al. Kidney injury molecule-1 expression in IgA nephropathy and its correlation with hypoxia and tubulointerstitial inflammation. Am J Physiol Renal Physiol. 2014;306:F885–F895.
   Google Scholar
• Zheng G, Wang Y, Mahajan D, et al. The role of tubulointerstitial inflammation. Kidney Int Suppl. 2005;94:S96–S100.
   Google Scholar
• Xu PC, Wei L, Shang WY, et al. Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria. BMC Nephrol. 2014;15:107.
   PubMed Web of Science ®Google Scholar
• Waanders F, Vaidya VS, van Goor H, et al. Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: A post hoc analysis of a randomized controlled trial. Am J Kidney Dis. 2009;53:16–25.
   PubMed Web of Science ®Google Scholar
• Nakagawa S, Masuda S, Nishihara K, Inui K. mTOR inhibitor everolimus ameliorates progressive tubular dysfunction in chronic renal failure rats. Biochem Pharmacol. 2010;79:67–76.
   PubMed Web of Science ®Google Scholar
• Hosohata K, Ando H, Takeshita Y, et al. Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats. Diab Vasc Dis Res. 2014;11:243–250.
   PubMed Web of Science ®Google Scholar
• Lim AI, Chan LY, Tang SC, Lai KN, Leung JC. Albumin and glycated albumin activate KIM-1 release in tubular epithelial cells through distinct kinetics and mechanisms. Inflamm Res. 2014;63:831–839.
   PubMed Web of Science ®Google Scholar
• Carlsson AC, Calamia M, Riserus U, et al. Kidney injury molecule (KIM)-1 is associated with insulin resistance: Results from two community-based studies of elderly individuals. Diabetes Res Clin Pract. 2014;103:516–521.
   PubMed Web of Science ®Google Scholar
• Nozaki Y, Kinoshita K, Yano T, et al. Estimation of kidney injury molecule-1 (Kim-1) in patients with lupus nephritis. Lupus. 2014;23:769–777.
   PubMed Web of Science ®Google Scholar
• Kuehn EW, Hirt MN, John AK, et al. Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2. Biochem Biophys Res Commun. 2007;364:861–866.
   PubMed Web of Science ®Google Scholar
• Abulezz S. KIM-1 expression in kidney allograft biopsies: Improving the gold standard. Kidney Int. 2008;73:522–523.
   PubMed Web of Science ®Google Scholar
• Malyszko J, Koc-Zorawska E, Malyszko JS, Mysliwiec M. Kidney injury molecule-1 correlates with kidney function in renal allograft recipients. Transplant Proc. 2010;42:3957–3959.
   PubMed Web of Science ®Google Scholar
• Zhang PL, Rothblum LI, Han WK, Blasick TM, Potdar S, Bonventre JV. Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Kidney Int. 2008;73:608–614.
   PubMed Web of Science ®Google Scholar
• Nogare AL, Dalpiaz T, Veronese FJ, Goncalves LF, Manfro RC. Noninvasive analyses of kidney injury molecule-1 messenger RNA in kidney transplant recipients with graft dysfunction. Transplant Proc. 2012;44:2297–2299.
   PubMed Web of Science ®Google Scholar
• Nogare AL, Veronese FV, Carpio VN, et al. Kidney injury molecule-1 expression in human kidney transplants with interstitial fibrosis and tubular atrophy. BMC Nephrol. 2015;16:19.
   PubMed Web of Science ®Google Scholar
• Song L, Xue L, Yu J, Zhao J, Zhang W, Fu Y. Kidney injury molecule-1 expression is closely associated with renal allograft damage. Bosn J Basic Med Sci. 2013;13:170–174.
   PubMed Web of Science ®Google Scholar
• Schroppel B, Kruger B, Walsh L, et al. Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol. 2010;21:536–542.
   PubMed Web of Science ®Google Scholar
• Morrissey JJ, London AN, Lambert MC, Kharasch ED. Sensitivity and specificity of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 for the diagnosis of renal cell carcinoma. Am J Nephrol. 2011;34:391–398.
   PubMed Web of Science ®Google Scholar
• Shalabi A, Abassi Z, Awad H, et al. Urinary NGAL and KIM-1: Potential association with histopathologic features in patients with renal cell carcinoma. World J Urol. 2013;31:1541–1545.
   PubMed Web of Science ®Google Scholar