Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells

References

• Nakanishi T, Nanami M, Kuragano T. The pathogenesis of CKD complications; attack of dysregulated iron and phosphate metabolism. Free Radic Biol Med. 2020;157:55–62.
   PubMed Web of Science ®Google Scholar
• Shroff R, Long DA, Shanahan C. Mechanistic insights into vascular calcification in CKD. J Am Soc Nephrol. 2013;24(2):179–189.
   PubMed Web of Science ®Google Scholar
• Lee SH, Ok S-H, Subbarao RB, et al. Vascular calcification – new insights into its mechanism. Int J Med Sci. 2020;17(1):21–32.
   PubMedGoogle Scholar
• Chang JR, Sun N, Liu Y, et al. Erythropoietin attenuates vascular calcification by inhibiting endoplasmic reticulum stress in rats with chronic kidney disease. Peptides. 2020; 123:170181.
   PubMed Web of Science ®Google Scholar
• Shi Y, Wang S, Peng H, et al. Fibroblast growth factor 21 attenuates vascular calcification by alleviating endoplasmic reticulum stress mediated apoptosis in rats. Int J Biol Sci. 2019;15(1):138–147.
   PubMed Web of Science ®Google Scholar
• Shanahan CM, Furmanik M. Endoplasmic reticulum stress in arterial smooth muscle cells: a novel regulator of vascular disease. Curr Cardiol Rev. 2017;13(2):94–105.
   PubMed Web of Science ®Google Scholar
• Guzel E, Arlier S, Guzeloglu-Kayisli O, et al. Endoplasmic reticulum stress and homeostasis in reproductive physiology and pathology. Int J Mol Sci. 2017;18:792.
   PubMed Web of Science ®Google Scholar
• Iurlaro R, Muñoz-Pinedo C. Cell death induced by endoplasmic reticulum stress. Febs J. 2016;283(14):2640–2652.
   PubMed Web of Science ®Google Scholar
• Ryoo HD. Long and short (timeframe) of endoplasmic reticulum stress-induced cell death. Febs J. 2016;283(20):3718–3722.
   PubMed Web of Science ®Google Scholar
• Nakagawa T, Zhu H, Morishima N, et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 2000;403(6765):98–103.
   PubMed Web of Science ®Google Scholar
• Zuo S, Kong D, Wang C, et al. CRTH2 promotes endoplasmic reticulum stress-induced cardiomyocyte apoptosis through M-calpain. EMBO Mol Med. 2018;10(3):e8237.
   PubMed Web of Science ®Google Scholar
• Coen G. Calcimimetics, parathyroid hormone, and vascular calcification in chronic kidney disease. Kidney Int. 2008;74(10):1229–1231.
   PubMed Web of Science ®Google Scholar
• Carrillo-López N, Panizo S, Alonso-Montes C, et al. High-serum phosphate and parathyroid hormone distinctly regulate bone loss and vascular calcification in experimental chronic kidney disease. Nephrol Dial Transplant. 2019;34(6):934–941.
   PubMed Web of Science ®Google Scholar
• Malluche HH, Blomquist G, Monier-Faugere MC, et al. High parathyroid hormone level and osteoporosis predict progression of coronary artery calcification in patients on dialysis. J Am Soc Nephrol. 2015;26(10):2534–2544.
   PubMed Web of Science ®Google Scholar
• Liu Y, Wu Y, Diao Z, et al. Resveratrol inhibits parathyroid hormone-induced apoptosis in human aortic smooth muscle cells by upregulating sirtuin 1. Ren Fail. 2019;41(1):401–407.
   PubMed Web of Science ®Google Scholar
• Guo Y, Bao S, Guo W, et al. Bone marrow mesenchymal stem cell-derived exosomes alleviate high phosphorus-induced vascular smooth muscle cells calcification by modifying microRNA profiles. Funct Integr Genomics. 2019;19(4):633–643.
   PubMed Web of Science ®Google Scholar
• Guo W, Ding J, Zhang A, et al. The inhibitory effect of quercetin on asymmetric dimethylarginine-induced apoptosis is mediated by the endoplasmic reticulum stress pathway in glomerular endothelial cells. Int J Mol Sci. 2014;15(1):484–503.
   PubMed Web of Science ®Google Scholar
• Mohlin C, Taylor L, Ghosh F, et al. Autophagy and ER-stress contribute to photoreceptor degeneration in cultured adult porcine retina. Brain Res. 2014; 1585:167–183.
   PubMed Web of Science ®Google Scholar
• García de la Cadena S, Massieu L. Caspases and their role in inflammation and ischemic neuronal death. Focus on caspase-12. Apoptosis. 2016;21(7):763–777.
   PubMed Web of Science ®Google Scholar
• Cozzolino M, Ciceri P, Galassi A, et al. The key role of phosphate on vascular calcification. Toxins(Basel). 2019; 11:213.
   PubMed Web of Science ®Google Scholar
• Chen J, Budoff MJ, Reilly MP, CRIC Investigators, et al. Coronary artery calcification and risk of cardiovascular disease and death among patients with chronic kidney disease. JAMA Cardiol. 2017;2(6):635–643.
   PubMed Web of Science ®Google Scholar
• Nelson AJ, Raggi P, Wolf M, et al. Targeting vascular calcification in chronic kidney disease. JACC Basic Transl Sci. 2020;5(4):398–412.
   PubMedGoogle Scholar
• Rogers MA, Aikawa E. Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery. Nat Rev Cardiol. 2019;16(5):261–274.
   PubMed Web of Science ®Google Scholar
• Lossi L, Castagna C, Merighi A. Caspase-3 mediated cell death in the normal development of the mammalian cerebellum. Int J Mol Sci. 2018; 19: 3999.
   PubMed Web of Science ®Google Scholar
• Masuda M, Miyazaki-Anzai S, Keenan AL, et al. Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells. JCI Insight. 2016;1(18):e88646.
   PubMed Web of Science ®Google Scholar
• Ochoa CD, Wu RF, Terada LS. ROS signaling and ER stress in cardiovascular disease. Mol Aspects Med. 2018; 63:18–29.
   PubMed Web of Science ®Google Scholar
• Panda DK, Bai X, Sabbagh Y, et al. Defective interplay between mTORC1 activity and endoplasmic reticulum stress-unfolded protein response in uremic vascular calcification. Am J Physiol Renal Physiol. 2018;314(6):F1046–1046F1061.
   PubMed Web of Science ®Google Scholar
• Duan XH, Chang JR, Zhang J, et al. Activating transcription factor 4 is involved in endoplasmic reticulum stress-mediated apoptosis contributing to vascular calcification. Apoptosis. 2013;18(9):1132–1144.
   PubMed Web of Science ®Google Scholar
• Zhu Q, Guo R, Liu C, et al. Endoplasmic reticulum stress-mediated apoptosis contributing to high glucose-induced vascular smooth muscle cell calcification. J Vasc Res. 2015;52(5):291–298.
   PubMed Web of Science ®Google Scholar
• Furmanik M, van Gorp R, Whitehead M, et al. Endoplasmic reticulum stress mediates vascular smooth muscle cell calcification via increased release of Grp78-Loaded extracellular vesicles. ATVB. 2021;41(2):898–914. ATVBAHA120315506.
   Google Scholar
• Maltais JS, Simard E, Froehlich U, et al. iRAGE as a novel carboxymethylated peptide that prevents advanced glycation end product-induced apoptosis and endoplasmic reticulum stress in vascular smooth muscle cells. Pharmacol Res. 2016; 104:176–185.
   PubMed Web of Science ®Google Scholar
• Shiozaki Y, Okamura K, Kohno S, et al. The CDK9-cyclin T1 complex mediates saturated fatty acid-induced vascular calcification by inducing expression of the transcription factor CHOP. J Biol Chem. 2018;293(44):17008–17020.
   PubMed Web of Science ®Google Scholar
• Zou Z, Wang L, Zhou Z, et al. Simultaneous incorporation of PTH(1-34) and nano-hydroxyapatite into chitosan/alginate hydrogels for efficient bone regeneration. Bioact Mater. 2021;6(6):1839–1851.
   PubMed Web of Science ®Google Scholar
• Ishikawa M, Akishita M, Kozaki K, et al. Amino-terminal fragment (1-34) of parathyroid hormone-related protein inhibits migration and proliferation of cultured vascular smooth muscle cells. Atherosclerosis. 1998;136(1):59–66.
   PubMed Web of Science ®Google Scholar
• Rashid G, Plotkin E, Klein O, et al. Parathyroid hormone decreases endothelial osteoprotegerin secretion: role of protein kinase a and C. Am J Physiol Renal Physiol. 2009;296(1):F60–66.
   PubMed Web of Science ®Google Scholar
• Benson T, Menezes T, Campbell J, et al. Mechanisms of vasodilation to PTH 1-84, PTH 1-34, and PTHrP 1-34 in rat bone resistance arteries. Osteoporos Int. 2016;27(5):1817–1826.
   PubMed Web of Science ®Google Scholar
• Ito N, Prideaux M, Wijenayaka AR, et al. Sclerostin directly stimulates osteocyte synthesis of fibroblast growth factor-23. Calcif Tissue Int. 2021;109(1):66–76.
   PubMed Web of Science ®Google Scholar
• Guo F, Han X, Wu Z, et al. ATF6a, a Runx2-activable transcription factor, is a new regulator of chondrocyte hypertrophy. J Cell Sci. 2016;129(4):717–728.
   PubMed Web of Science ®Google Scholar