Predictors, prevalence and prognostic role of pulmonary hypertension in patients with chronic kidney disease: a systematic review and meta-analysis

References

• Humbert M, Kovacs G, Hoeper MM, et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J. 2022;43(38):3618–3731. doi: 10.1093/eurheartj/ehac237.
   PubMed Web of Science ®Google Scholar
• Simonneau G, Montani D, Celermajer DS, et al. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. Eur Respir J. 2019;53(1):1801913. doi: 10.1183/13993003.01913-2018.
   PubMed Web of Science ®Google Scholar
• Oldroyd SH, Manek G, Bhardwaj A. Pulmonary hypertension. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024. 2024 May 1. In.
   Google Scholar
• Corciova FC, Arsenescu-Georgescu C. Prognostic factors in pulmonary hypertension. Maedica (Bucur). 2012;7(1):30–37.
   PubMedGoogle Scholar
• Hoeper MM, Bogaard HJ, Condliffe R, et al. Definitions and diagnosis of pulmonary hypertension. J Am Coll Cardiol. 2013;62(25 Suppl):D42–50. doi: 10.1016/j.jacc.2013.10.032.
   PubMed Web of Science ®Google Scholar
• Edmonston DL, Parikh KS, Rajagopal S, et al. Pulmonary hypertension subtypes and mortality in CKD. Am J Kidney Dis. 2020;75(5):713–724. doi: 10.1053/j.ajkd.2019.08.027.
   PubMed Web of Science ®Google Scholar
• Rroji M, Cafka M, Seferi S, et al. The potential effect of cardiac function on pulmonary hypertension, other risk factors, and its impact on survival in dialysis patients. Int Urol Nephrol. 2021;53(2):343–351. doi: 10.1007/s11255-020-02655-z.
   PubMed Web of Science ®Google Scholar
• Tang M, Batty JA, Lin C, et al. Pulmonary hypertension, mortality, and cardiovascular disease in CKD and ESRD patients: a systematic review and meta-analysis. Am J Kidney Dis. 2018;72(1):75–83. doi: 10.1053/j.ajkd.2017.11.018.
   PubMed Web of Science ®Google Scholar
• Akmal M, Barndt RR, Ansari AN, et al. Excess PTH in CRF induces pulmonary calcification, pulmonary hypertension and right ventricular hypertrophy. Kidney Int. 1995;47(1):158–163. doi: 10.1038/ki.1995.18.
   PubMed Web of Science ®Google Scholar
• Harp RJ, Stavropoulos SW, Wasserstein AG, et al. Pulmonary hypertension among end-stage renal failure patients following hemodialysis access thrombectomy. Cardiovasc Intervent Radiol. 2005;28(1):17–22. doi: 10.1007/s00270-004-0223-1.
   PubMed Web of Science ®Google Scholar
• Santosh S, Chu C, Mwangi J, et al. Changes in pulmonary artery systolic pressure and right ventricular function in patients with end-stage renal disease on maintenance dialysis. Nephrology (Carlton). 2019;24(1):74–80. doi: 10.1111/nep.13183.
   PubMed Web of Science ®Google Scholar
• Walther CP, Nambi V, Hanania NA, et al. Diagnosis and management of pulmonary hypertension in patients with CKD. Am J Kidney Dis. 2020;75(6):935–945. doi: 10.1053/j.ajkd.2019.12.005.
   PubMed Web of Science ®Google Scholar
• Kaw R, Pasupuleti V, Deshpande A, et al. Pulmonary hypertension: an important predictor of outcomes in patients undergoing non-cardiac surgery. Respir Med. 2011;105(4):619–624. doi: 10.1016/j.rmed.2010.12.006.
   PubMed Web of Science ®Google Scholar
• Bolignano D, Pisano A, Coppolino G, et al. Pulmonary hypertension predicts adverse outcomes in renal patients: a systematic review and meta-analysis. Ther Apher Dial. 2019;23(4):369–384. doi: 10.1111/1744-9987.12777.
   PubMed Web of Science ®Google Scholar
• Shang W, Li Y, Ren Y, et al. Prevalence of pulmonary hypertension in patients with chronic kidney disease without dialysis: a meta-analysis. Int Urol Nephrol. 2018;50(8):1497–1504. doi: 10.1007/s11255-018-1853-6.
   PubMed Web of Science ®Google Scholar
• Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. doi: 10.1136/bmj.n71.
   PubMed Web of Science ®Google Scholar
• Wells G, Shea B, O'Connell D. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses; 2009. Ottawa (ON): Ottawa Hospital Research Institute, 2009. Available:http://www.ohri.ca/programs/clinical_epidemiology/oxford.htm.
   Google Scholar
• DerSimonian R, Laird N. Meta-analysis in clinical trials revisited. Contemp Clin Trials. 2015;45(Pt A):139–145. doi: 10.1016/j.cct.2015.09.002.
   PubMed Web of Science ®Google Scholar
• Ades AE, Lu G, Higgins JP. The interpretation of random-effects meta-analysis in decision models. Med Decis Making. 2005;25(6):646–654. doi: 10.1177/0272989x05282643.
   PubMed Web of Science ®Google Scholar
• Deeks JJ, Higgins JPT, Altman DG. Analyzing data and undertaking meta-analyses. In: Higgins J, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions 5.0.1. Oxford (UK): The Cochrane Collaboration; 2008.
   Google Scholar
• Higgins JP, Thompson SG, Deeks JJ, et al. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–560. doi: 10.1136/bmj.327.7414.557.
   PubMed Web of Science ®Google Scholar
• Tobias A. Assessing the influence of a single study in meta-analysis. Stata Tech Bull. 1999;47:15–17.
   Google Scholar
• Altman DG, Bland JM. Interaction revisited: the difference between two estimates. BMJ. 2003;326(7382):219–219. doi: 10.1136/bmj.326.7382.219.
   PubMed Web of Science ®Google Scholar
• Egger M, Davey Smith G, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–634. doi: 10.1136/bmj.315.7109.629.
   PubMed Web of Science ®Google Scholar
• Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50(4):1088–1101. doi: 10.2307/2533446.
   PubMed Web of Science ®Google Scholar
• Yigla M, Nakhoul F, Sabag A, et al. Pulmonary hypertension in patients with end-stage renal disease. Chest. 2003;123(5):1577–1582. doi: 10.1378/chest.123.5.1577.
   PubMed Web of Science ®Google Scholar
• Kumbar L, Fein PA, Rafiq MA, et al. Pulmonary hypertension in peritoneal dialysis patients. Adv Perit Dial. 2007;23:127–131.
   PubMedGoogle Scholar
• Havlucu Y, Kursat S, Ekmekci C, et al. Pulmonary hypertension in patients with chronic renal failure. Respiration. 2007;74(5):503–510. doi: 10.1159/000102953.
   PubMed Web of Science ®Google Scholar
• Issa N, Krowka MJ, Griffin MD, et al. Pulmonary hypertension is associated with reduced patient survival after kidney transplantation. Transplantation. 2008;86(10):1384–1388. doi: 10.1097/TP.0b013e318188d640.
   PubMed Web of Science ®Google Scholar
• Abdelwhab S, Elshinnawy S. Pulmonary hypertension in chronic renal failure patients. Am J Nephrol. 2008;28(6):990–997. doi: 10.1159/000146076.
   PubMed Web of Science ®Google Scholar
• Yigla M, Banderski R, Azzam ZS, et al. Arterio-venous access in end-stage renal disease patients and pulmonary hypertension. Ther Adv Respir Dis. 2008;2(2):49–53. doi: 10.1177/1753465808089456.
   PubMedGoogle Scholar
• Yigla M, Fruchter O, Aharonson D, et al. Pulmonary hypertension is an independent predictor of mortality in hemodialysis patients. Kidney Int. 2009;75(9):969–975. doi: 10.1038/ki.2009.10.
   PubMed Web of Science ®Google Scholar
• Ramasubbu K, Deswal A, Herdejurgen C, et al. A prospective echocardiographic evaluation of pulmonary hypertension in chronic hemodialysis patients in the United States: prevalence and clinical significance. Int J Gen Med. 2010;3:279–286. doi: 10.2147/ijgm.S12946.
   PubMedGoogle Scholar
• Kiykim AA, Horoz M, Ozcan T, et al. Pulmonary hypertension in hemodialysis patients without arteriovenous fistula: the effect of dialyzer composition. Ren Fail. 2010;32(10):1148–1152. doi: 10.3109/0886022x.2010.516854.
   PubMed Web of Science ®Google Scholar
• Zlotnick DM, Axelrod DA, Chobanian MC, et al. Non-invasive detection of pulmonary hypertension prior to renal transplantation is a predictor of increased risk for early graft dysfunction. Nephrol Dial Transplant. 2010;25(9):3090–3096. doi: 10.1093/ndt/gfq141.
   PubMed Web of Science ®Google Scholar
• Agarwal R. Prevalence, determinants and prognosis of pulmonary hypertension among hemodialysis patients. Nephrol Dial Transplant. 2012;27(10):3908–3914. doi: 10.1093/ndt/gfr661.
   PubMed Web of Science ®Google Scholar
• Yoo HH, Martin LC, Kochi AC, et al. Could albumin level explain the higher mortality in hemodialysis patients with pulmonary hypertension? BMC Nephrol. 2012;13(1):80. doi: 10.1186/1471-2369-13-80.
   PubMedGoogle Scholar
• Pabst S, Hammerstingl C, Hundt F, et al. Pulmonary hypertension in patients with chronic kidney disease on dialysis and without dialysis: results of the PEPPER-study. PLoS One. 2012;7(4):e35310. doi: 10.1371/journal.pone.0035310.
   PubMed Web of Science ®Google Scholar
• Said K, Hassan M, Baligh E, et al. Ventricular function in patients with end-stage renal disease starting dialysis therapy: a tissue Doppler imaging study. Echocardiography. 2012;29(9):1054–1059. doi: 10.1111/j.1540-8175.2012.01749.x.
   PubMed Web of Science ®Google Scholar
• Stallworthy EJ, Pilmore HL, Webster MW, et al. Do echocardiographic parameters predict mortality in patients with end-stage renal disease? Transplantation. 2013;95(10):1225–1232. doi: 10.1097/TP.0b013e31828dbbbe.
   PubMed Web of Science ®Google Scholar
• El-Azeem AA, Hamdy G, Saraya M, et al. The role of procalcitonin as a guide for the diagnosis, prognosis, and decision of antibiotic therapy for lower respiratory tract infections. Egypt J Chest Dis Tuberc. 2013;62(4):687–695. doi: 10.1016/j.ejcdt.2013.07.017.
   PubMedGoogle Scholar
• Green D, Ritchie JP, Abidin N, et al. The association of ECG and echocardiographic abnormalities with sudden cardiac death in a dialysis patient cohort. J Nephrol. 2014;27(1):81–86. doi: 10.1007/s40620-013-0013-4.
   PubMed Web of Science ®Google Scholar
• Li Z, Liu S, Liang X, et al. Pulmonary hypertension as an independent predictor of cardiovascular mortality and events in hemodialysis patients. Int Urol Nephrol. 2014;46(1):141–149. doi: 10.1007/s11255-013-0486-z.
   PubMed Web of Science ®Google Scholar
• Yang QM, Bao XR. Pulmonary hypertension in patients with stage 1-3 chronic kidney disease. Genet Mol Res. 2014;13(3):5695–5703. doi: 10.4238/2014.July.25.25.
   PubMed Web of Science ®Google Scholar
• Li Z, Liang X, Liu S, et al. Pulmonary hypertension: epidemiology in different CKD stages and its association with cardiovascular morbidity. PLoS One. 2014;9(12):e114392. doi: 10.1371/journal.pone.0114392.
   PubMed Web of Science ®Google Scholar
• Bolignano D, Lennartz S, Leonardis D, et al. High estimated pulmonary artery systolic pressure predicts adverse cardiovascular outcomes in stage 2-4 chronic kidney disease. Kidney Int. 2015;88(1):130–136. doi: 10.1038/ki.2015.27.
   PubMed Web of Science ®Google Scholar
• Kim SC, Chang HJ, Kim MG, et al. Relationship between pulmonary hypertension, peripheral vascular calcification, and major cardiovascular events in dialysis patients. Kidney Res Clin Pract. 2015;34(1):28–34. doi: 10.1016/j.krcp.2015.01.003.
   PubMedGoogle Scholar
• Xu Q, Xiong L, Fan L, et al. Association of pulmonary hypertension with mortality in incident peritoneal dialysis patients. Perit Dial Int. 2015;35(5):537–544. doi: 10.3747/pdi.2013.00332.
   PubMed Web of Science ®Google Scholar
• Babua C, Kalyesubula R, Okello E, et al. Pattern and presentation of cardiac diseases among patients with chronic kidney disease attending a national referral hospital in Uganda: a cross sectional study. BMC Nephrol. 2015;16(1):126. doi: 10.1186/s12882-015-0128-z.
   PubMedGoogle Scholar
• Genctoy G, Arikan S, Gedik O. Secondary hyperparathyroidism is associated with pulmonary hypertension in older patients with chronic kidney disease and proteinuria. Int Urol Nephrol. 2015;47(2):353–358. doi: 10.1007/s11255-014-0889-5.
   PubMed Web of Science ®Google Scholar
• Hsieh CW, Lee CT, Chen CC, et al. Pulmonary hypertension in patients on chronic hemodialysis and with heart failure. Hemodial Int. 2016;20(2):208–217. doi: 10.1111/hdi.12380.
   PubMed Web of Science ®Google Scholar
• Navaneethan SD, Roy J, Tao K, et al. Prevalence, predictors, and outcomes of pulmonary hypertension in CKD. J Am Soc Nephrol. 2016;27(3):877–886. doi: 10.1681/asn.2014111111.
   PubMed Web of Science ®Google Scholar
• Reque J, Quiroga B, Ruiz C, et al. Pulmonary hypertension is an independent predictor of cardiovascular events and mortality in haemodialysis patients. Nephrology (Carlton). 2016;21(4):321–326. doi: 10.1111/nep.12595.
   PubMed Web of Science ®Google Scholar
• Reque J, Garcia-Prieto A, Linares T, et al. Pulmonary hypertension is associated with mortality and cardiovascular events in chronic kidney disease patients. Am J Nephrol. 2017;45(2):107–114. doi: 10.1159/000453047.
   PubMed Web of Science ®Google Scholar
• Suresh H, Arun BS, Moger V, et al. Cardiorenal syndrome type 4: a study of cardiovascular diseases in chronic kidney disease. Indian Heart J. 2017;69(1):11–16. doi: 10.1016/j.ihj.2016.07.006.
   PubMedGoogle Scholar
• Selvaraj S, Shah SJ, Ommerborn MJ, et al. Pulmonary hypertension is associated with a higher risk of heart failure hospitalization and mortality in patients with chronic kidney disease: the Jackson Heart Study. Circ Heart Fail. 2017;10(6):1–8. doi: 10.1161/circheartfailure.116.003940.
   PubMed Web of Science ®Google Scholar
• O'Leary JM, Assad TR, Xu M, et al. Pulmonary hypertension in patients with chronic kidney disease: invasive hemodynamic etiology and outcomes. Pulm Circ. 2017;7(3):674–683. doi: 10.1177/2045893217716108.
   PubMed Web of Science ®Google Scholar
• Zhang Q, Wang L, Zeng H, et al. Epidemiology and risk factors in CKD patients with pulmonary hypertension: a retrospective study. BMC Nephrol. 2018;19(1):70. doi: 10.1186/s12882-018-0866-9.
   PubMedGoogle Scholar
• Miri M, Hejazi S, Maghsoudlou F, et al. Prevalence of pulmonary hypertension in end-stage renal disease patients undergoing hemodialysis and peritoneal dialysis at a Referral Center in Mashhad, Iran, From 2015 to 2016. Iran J Kidney Dis. 2018;12(6):364–368.
   PubMed Web of Science ®Google Scholar
• Singh NP, Nautiyal A, Karol A, et al. Pulmonary hypertension in patients with end stage renal disease on maintenance hemodialysis-a cross-sectional study. J Assoc Physicians India. 2018;66(12):26–29.
   PubMedGoogle Scholar
• Tudoran M, Ciocarlie T, Mates A, et al. Pulmonary hypertension in patients with end stage renal disease undergoing hemodialysis. Niger J Clin Pract. 2020;23(2):198–204. doi: 10.4103/njcp.njcp_278_19.
   PubMed Web of Science ®Google Scholar
• Orihuela O, de Jesus Ventura M, Carmona-Ruiz HA, et al. Pulmonary hypertension in patients starting peritoneal dialysis. Arch Med Res. 2020;51(3):254–260. doi: 10.1016/j.arcmed.2020.02.004.
   PubMed Web of Science ®Google Scholar
• Nithiya N, Indhumathi E, Jagadeswaran D, et al. Pulmonary hypertension - prevalence, risk factors, and its association with vascular calcification in chronic kidney disease and hemodialysis patients. Saudi J Kidney Dis Transpl. 2020;31(2):380–387. doi: 10.4103/1319-2442.284012.
   PubMed Web of Science ®Google Scholar
• Obi C, Frost AE, Graviss EA, et al. The association of pretransplant pulmonary hypertension with patient and graft survival after kidney transplantation: a retrospective cohort study. Transplant Proc. 2020;52(10):3023–3032. doi: 10.1016/j.transproceed.2020.05.003.
   PubMed Web of Science ®Google Scholar
• Zhang X, Zhao W, Ma X, et al. Prognostic value of pulmonary hypertension in pre-dialysis chronic kidney disease patients. Int Urol Nephrol. 2020;52(12):2329–2336. doi: 10.1007/s11255-020-02589-6.
   PubMed Web of Science ®Google Scholar
• Engole YM, Lepira FB, Nlandu YM, et al. Prevalence and factors associated with pulmonary arterial hypertension on maintenance hemodialysis patients in Kinshasa, Democratic Republic of Congo: a cross-sectional study. BMC Nephrol. 2020;21(1):460. doi: 10.1186/s12882-020-02131-x.
   PubMed Web of Science ®Google Scholar
• Li Y, Zhang Y, Wang J, et al. Pulmonary hypertension in end-stage renal disease patients on dialysis and predialysis patients. Clin Invest Med. 2020;43(3):E44–E48. doi: 10.25011/cim.v43i3.34631.
   PubMed Web of Science ®Google Scholar
• Mann A, Kampani G, Bansal S, et al. Study of pulmonary arterial hypertension in patients of chronic kidney disease stage IV and V. J Assoc Physicians India. 2021;69(10):11–12.
   PubMedGoogle Scholar
• Alıcı G, Waberi MM, Mohamud MA, et al. Pulmonary hypertension among maintenance hemodialysis patients in Somalia: a hospital-based observational study. Egypt Heart J. 2022;74(1):24. doi: 10.1186/s43044-022-00261-1.
   PubMedGoogle Scholar
• Anandan AK, Sankaranarayanan G, Samuel U, et al. A cross-sectional study on pulmonary hypertension in patients with stage 5 chronic kidney disease. Saudi J Kidney Dis Transpl. 2022;33(Supplement):S1–s11. doi: 10.4103/1319-2442.375086.
   PubMedGoogle Scholar
• Rabih F, Holden RL, Vasanth P, et al. Effect of pulmonary hypertension on 5-year outcome of kidney transplantation. Pulm Circ. 2022;12(1):e12010. doi: 10.1002/pul2.12010.
   PubMedGoogle Scholar
• Singh S, Aggarwal V, Pandey UK, et al. Study of left ventricular systolic dysfunction, left ventricular diastolic dysfunction and pulmonary hypertension in CKD 3b-5ND patients-A single centre cross-sectional study. Nefrologia (Engl Ed). 2023;43(5):596–605. doi: 10.1016/j.nefroe.2022.06.005.
   PubMed Web of Science ®Google Scholar
• Liu X, Li X, Duan J, et al. The percentage of circulating fibrocytes is associated with increased morbidity of pulmonary hypertension in patients on hemodialysis. Semin Dial. 2024;37(1):43–51. doi: 10.1111/sdi.13139.
   PubMed Web of Science ®Google Scholar
• Gaur J, Singh RK, Kulkarni C, et al. Assessment of pulmonary hypertension in chronic kidney disease patients using Doppler echocardiography. Heart Views. 2023;24(1):24–28. doi: 10.4103/heartviews.heartviews_31_22.
   PubMedGoogle Scholar
• Park M, Hsu CY, Li Y, et al. Associations between kidney function and subclinical cardiac abnormalities in CKD. J Am Soc Nephrol. 2012;23(10):1725–1734. doi: 10.1681/asn.2012020145.
   PubMed Web of Science ®Google Scholar
• Giaid A. Nitric oxide and endothelin-1 in pulmonary hypertension. Chest. 1998;114(3 Suppl):208s–212S. doi: 10.1378/chest.114.3_supplement.208s.
   PubMed Web of Science ®Google Scholar
• Jarava C, Martí V, Gurpegui ML, et al. Pulmonary calcification in chronic dialysis patients. Nephrol Dial Transplant. 1993;8(7):673–674.
   PubMed Web of Science ®Google Scholar
• Bolignano D, Rastelli S, Agarwal R, et al. Pulmonary hypertension in CKD. Am J Kidney Dis. 2013;61(4):612–622. doi: 10.1053/j.ajkd.2012.07.029.
   PubMed Web of Science ®Google Scholar
• Buemi M, Senatore M, Gallo GC, et al. Pulmonary hypertension and erythropoietin. Kidney Blood Press Res. 2007;30(4):248–252. doi: 10.1159/000104443.
   PubMed Web of Science ®Google Scholar
• Coppolino G, Bolignano D, Campo S, et al. Circulating progenitor cells after cold pressor test in hypertensive and uremic patients. Hypertens Res. 2008;31(4):717–724. doi: 10.1291/hypres.31.717.
   PubMed Web of Science ®Google Scholar
• Campia U, Cardillo C, Panza JA. Ethnic differences in the vasoconstrictor activity of endogenous endothelin-1 in hypertensive patients. Circulation. 2004;109(25):3191–3195. doi: 10.1161/01.Cir.0000130590.24107.D3.
   PubMed Web of Science ®Google Scholar
• Treiber FA, Kapuku GK, Davis H, et al. Plasma endothelin-1 release during acute stress: role of ethnicity and sex. Psychosom Med. 2002;64(5):707–713. doi: 10.1097/01.psy.0000021952.59258.1c.
   PubMed Web of Science ®Google Scholar
• Wang N, Guo Z, Gong X, et al. A nomogram for predicting the risk of pulmonary hypertension for patients with chronic obstructive pulmonary disease. Int J Gen Med. 2022;15:5751–5762. doi: 10.2147/ijgm.S363035.
   PubMed Web of Science ®Google Scholar
• Galiè N, Humbert M, Vachiery JL, et al. ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Respir J. 2015;46(4):903–975. 2015 doi: 10.1183/13993003.01032-2015.
   PubMed Web of Science ®Google Scholar
• George MG, Schieb LJ, Ayala C, et al. Pulmonary hypertension surveillance: united States, 2001 to 2010. Chest. 2014;146(2):476–495. doi: 10.1378/chest.14-0527.
   PubMed Web of Science ®Google Scholar
• Lau EM, Humbert M, Celermajer DS. Early detection of pulmonary arterial hypertension. Nat Rev Cardiol. 2015;12(3):143–155. doi: 10.1038/nrcardio.2014.191.
   PubMed Web of Science ®Google Scholar
• Couser WG, Remuzzi G, Mendis S, et al. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int. 2011;80(12):1258–1270. doi: 10.1038/ki.2011.368.
   PubMed Web of Science ®Google Scholar
• International Society of Nephrology KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Off J Int Soc Nephrol. 2013;3:163.
   Google Scholar
• Milik A, Hrynkiewicz E. KDIGO 2012 Clinical practice guideline for the evaluation and management of chronic kidney disease. kidney international supplements. J Int Soc Nephrol. 2013;158:825–830.
   Google Scholar
• Collins AJ, Foley RN, Chavers B, et al. United States Renal Data System 2011 Annual Data Report: Atlas of chronic kidney disease & end-stage renal disease in the United States. Am J Kidney Dis. 2012;59(1 Suppl 1):A7, e1–420. doi: 10.1053/j.ajkd.2011.11.015.
   PubMedGoogle Scholar
• Mekonen MW, Birahan KA, Chekole DM. Determinants of overall survival of kidney failure for patients receiving dialysis in Saint Geberial General Hospital. Addis Ababa Ethiopia. J Kidney. 2020;6:2472–1220.
   Google Scholar
• Villain C, Liabeuf S, Metzger M, et al. Impact of age on cardiovascular drug use in patients with chronic kidney disease. Clin Kidney J. 2020;13(2):199–207. doi: 10.1093/ckj/sfz063.
   PubMed Web of Science ®Google Scholar
• Astor BC, Hallan SI, Miller ER, 3rd, et al. Glomerular filtration rate, albuminuria, and risk of cardiovascular and all-cause mortality in the US population. Am J Epidemiol. 2008;167(10):1226–1234. doi: 10.1093/aje/kwn033.
   PubMed Web of Science ®Google Scholar
• de Boer IH, Katz R, Cao JJ, et al. Cystatin C, albuminuria, and mortality among older adults with diabetes. Diabetes Care. 2009;32(10):1833–1838. doi: 10.2337/dc09-0191.
   PubMed Web of Science ®Google Scholar