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Research Article

Short Chain Fatty Acids, Menaquinones and Ubiquinones and Their Effects on the Host

Pages 209-215 | Published online: 11 Jul 2009

References

  • Cummings JH. Fermentation in the human large intestine: evidence and implication for health. Lancet 1985; 1: 1206–8.
  • Mortenson PB, Clausen MR. Short-chain fatty acids in the human colon: relation to gastrointestinal health and diseases. Scand J Gastroenterol 1996; 31 Suppl 216: 132–48.
  • Wolin MJ, Miller TL. Carbohydrate fermentation. In: Hent-ges DA, ed. Human intestinal flora in health and disease. New York: Academic Press, 1983: 147–65.
  • Scheppach W. Effects of short-chain fatty acids on gut mor-phology and function. Gut 1994; 36 Suppl 1: S35–8.
  • Gorbach S, Mayhew J, Bartlett J, Thadepalli H, Onderdonk A. Rapid diagnosis of anaerobic infections by direct gas liquid chromatography of clinical specimens. J Clin Invest 1976; 57: 478–84.
  • Siegel I. Permeability of oral mucosa to organic acid. J Dent Res 1977; 56 (Suppl): 52.
  • Wisker E, Feldheim W. Energy value of fermentation. In: Binder H, Cummings J, Soergel KH, eds. Short chain fatty acids. London: Kluwer Academic Publishers, 1994: 20–8.
  • Roediger WE. The role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gastroenterology 1980; 21: 793–8.
  • Roediger WE. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology 1982; 83: 424–9.
  • Cook SI, Sellin JH. Short chain fatty acids in health and disease. Aliment Pharmacol Ther 1998; 12: 499–507.
  • Roediger WE, Moore A. Effect of short-chain fatty acid on sodium absorption in isolated human colon perfused through the vascular bed. Dig Dis Sci 1981; 26: 100–6.
  • Roediger WE, Rae DA. Trophic effect of short chain fatty acids on mucosal handling of ions by the defunctioned colon. Br J Surg 1982; 69: 23–5.
  • Sellin JH, DeSoignie R. Short-chain fatty acid adsorption in rabbit colon in vitro. Gastroenterology 1990; 99: 676–83.
  • Friedel D, Levine GM. Effect of short chain fatty acid on colonic function and structure. J Parenteral Enteral Nutr 1992; 16: 1–4.
  • Mortensen FV, Nielsen H, Mulvany MJ, Hessov I. Short chain fatty acids dilate isolate human colonic resistance arter-ies. Gut 1990; 31: 1391–4.
  • Frankel WO, Zhang W, Singh A, et al. Mediation of the trophic effects of short chain fatty acids on rat jejunum and colon. Gastroenterology 1994; 106: 375–80.
  • Kvietys PR, Granger DN. Effects of volatile fatty acids on blood flow and oxygen uptake by the dog colon. Gastroen-terology 1981; 80: 962–9.
  • Koruda MJ, Rolando H, Rolandelli RH, Settle RG, Zim-maro DM, Rombeau JL. Effect of parenteral nutrition sup-plemented with short-chain fatty acids on adaptation to massive small bowel resection. Gastroenterology 1988; 95: 715–20.
  • Royall D, Wolever TMS, Jeejeebhoy KN. Clinical significance of colonic fermentation. Am J Gastroentero11990; 83: 424–9.
  • Wolover TMS, Spadafora P, Eshuis H. Interaction between colonic acetate and propionate in humans. Am J Clin Nutr 1991; 53: 681–7.
  • Jenkins DJ. Editorial. Am J Gastroenterol 1989; 84: 1362–4.
  • Ropert A, Cherbut C, Le Quellec A, Holst JJ, Fu-Chenh X, et al. Colonic fermentation and proximal gastric tone in humans. Gastroenterology 1996; 11: 289–96.
  • Fich A, Philips SF, Hakim NS, Brown ML, Zinsmeister AR. Stimultion of ileal emptying by short chain fatty acids. Dig Dis Sci 1989; 34: 1516–20.
  • Richardson A, Delbridge AT, Brown NJ, Rumsey RDE, Read NW. Short chain fatty acids in the terminal ileum accelarate stomach to cacum transit time in the rat. Gut 1991; 32: 266–9.
  • Yajima T. Effect of sodium propionate on the contractile response of the rat ileum in situ. Japan J Pharmacol 1984; 35: 265–71.
  • Cherbut C, Aubé AC, Blottiere HM, Galmiche JP. Effects of short-chain fatty acids on gastrointestinal motility. Scand J Gastroenterol 1997; Suppl 222: 58–61.
  • Clausen MR, Tuede M, Mortensen PB. Short-chain fatty acids in pouch contents from patients with and without pouchitis after ileal pouch-anal anastomosis. Gastroenterol-ogy 1992; 103: 1144–53.
  • Hang JM, Soergel KH, Komorwoski RA, Wood CM. Treat-ment of diversion colitis with short-chain fatty acid irrigation. N Eng J Med 1989; 320: 23–8.
  • Vernia P, Mercheggiano R, Caprilli R, Frieri G, Corraro G, Valpiani D. Short chain fatty acid topical treatment in distal ulcerative colitis. Aliment Pharmacol Ther 1995; 9: 309–13.
  • Clausen MR, Bannen H, Tuede M, Mortensen PB. Colonic fermentation to short chain fatty acid is decreased in antibi-otic-associated diarrhea. Gastroenterology 1991; 101: 1497–504.
  • Rabbiani GH, John Albert M, Hamidur Rahman ASM, Moyenul Isalm M, Nasirul Islam KM, Adam K. Short-chain fatty acids improve clinical, pathological, and microbiologic features of experimental shigellosis. J Infect Dis 1999; 179: 390–7.
  • Hentges DJ. Influence of pH on the inhibitory activity of formic and acetic acids for Shigella. J Bacteriol 1967; 93: 2029–30.
  • Scheppach W, Sommer H, Kirchner T, et al. Effect of bu-tyrate on the colonic mucosa in distal ulcerative colitis. Gas-troenterology 1992; 103: 51–6.
  • Guillemot F, Colombel JF, Neut C, et al. Therapy of DC by short chain fatty acids. Dis Colon Rectum 1991; 34: 861–4.
  • Steinhart AH, Hirnki T, Brzezinski A, Baker JP. Treatment of left-sided ulcerative colitis with butyrate enemas: a con-trolled trial. Aliment Pharmacol Ther 1996; 10: 729–36.
  • Svendsen P. The effects of volatile fatty acids and lactic acid on rumen motility in sheep. Nord Vet Med 1973; 25: 226–31.
  • Galfi P, Neogrady S, Veresegyhazy T, Kutas F. Demonstra-tion of keratinizing effect of n-butyrate on day-old chicken crop epithelium. Zentralbl Veterinarmeid A 1985; 32: 146–50.
  • Sakata T, Tamate H. Rumen epithelial cell proliferation accelerated by rapid increase in intraruminal butyrate. J Dairy Sci 1978; 61: 1109–13.
  • Popoff MR, Jolivet-Reyanaud C, Carlier JP. Cytotoxic activ-ity of Clostridium butyricum supernatants induced by bu-tyrate. FEMS Microbiol Lett 1987; 43: 95–100.
  • O'Keefe SJ, Kidd M, Espitalier Noel G, Owira P. Rarity of colon cancer in Africans is associated with low animal product consumption, not fiber. Am J Gastroenterology 1999; 94: 1373–80.
  • Reddy BS. Role of dietary fiber in colon cancer: an overview. Am J Med 1999; 106: 16S–9S.
  • Fuchs CS, Giovannucci EL, Colditz GA, Hunter DJ, Stampfer MJ, Rosner B, Speizer FE, Willet WC. Dietary fiber and the risk of colorectal cancer and adenoma in women. N Engl J Med 1999; 340: 169–76.
  • Alberts DS, Martinez ME, Roe DJ, Guillen Rodriguez JM, Marshall JR, van Leeuwen JB, Reid ME, Ritenbaugh C, Vargas PA, Bhattacharyya AB, Eamst DL, Sampliner RE. Lack of effect of a high-fiber cereal supplement on the recurrence of colorectal adenomas. Phoenix Colon Cancer Prevention Physicians' Network. N Engl J Med 2000; 342: 1156–62.
  • McIntyre A, Gibson PR, Young GP. Butyrate production from dietary fiber and protection against large bowel cancer in a rat model. Gut 1993; 34: 386–91.
  • Weaver GA, Krause JA, Miller TL, Wolin MJ. Short chain fatty acid distribution of enema samples from a sig-moidoscopy population: an association of high acetate and low butyrate ratios with adenomatous polyps and colon can-cer. Gut 1988; 29: 1539–43.
  • Kru J. Effects of sodium butyrate, a new pharmacological agent, on cells in culture. Mol Cell Biochem 1982; 42: 65–82.
  • Scheppach W, Bartran HP, Richter F. Role of short chain fatty acids in the prevention of colorectal cancer. Eur J Cancer 1995; 31A: 1077–80.
  • Tanaka Y, Bush K, Eguchi T, Ikekawa N, Takaguchi T, Kobayashi Y, Higgins PJ. Effects of 1,25-dihydroxyvitamin D3 and its analogs on butyrate-induced differentiation of Ht-29 human colonic carcinoma cells and on reversal of the differentiated phenotype. Arch Biochem Biophys 1990; 276: 415–23.
  • Hague A, Elder DJ, Hicks DJ, Paraskeva C. Apoptosis in colorectal tumor cells: induction by the short fatty acids butyrate, propionate and acetate and by the bile salt deoxy-cholate. Int .1 Cancer 1995; 60: 400–6.
  • Hague A, Diaz GD, Hicks DJ, Krajewski S, Reed JC, Paraskeva C. Bc1-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bc1-2 does not protect against bak-mediated apoptosis. Int .1 Cancer 1997; 72: 898–905.
  • Chittenden T, Harrington EA, O'Connor R, Flemington C, Lutz RJ, Evan GI, Guild BC. Induction of apoptosis by the bc1-2 homologue bak. Nature (London) 1995; 374: 733–6.
  • Farrow SN, White JHM, Martinou I, Raven T, Pun K-T, Grinham CJ, Martinou J-C, Brown R. Cloning of a bc1-2 homologue by interaction with adenovirus EIB 19K. Nature (London) 1995; 371: 731–3.
  • Kiefer MC, Brauer MJ, Powers VC, Wu JJ, Umansky SR, Tomei LD, Barr PJ. Modulation of apoptosis by the widely distributed bc1-2 homologue bak. Nature (London) 1995; 374: 736–9.
  • Hass R, Buscke R, Luciano L, Reale E, Engelherdt WV. Lack of butyrate is associated with induction of Bax and subse-quent apoptosis in the proximal colon of guinea pig. Gas-troenterology 1997; 112: 875–81.
  • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bc1-2 heterodimer-izes in vivo with a conserved homolog, bax, that accelerates programmed cell death. Cell 1993; 74: 609–19.
  • Whitlock JP, Galeazzi D, Schulman H. Acetylation and cal-cium dependent phosphorilation of histone H3 in nuclei from butyrate treated Hela cells. J Biol Chem 1983; 258: 1299–304.
  • Nakano K, Mizuno T, Sowa Y, Orita T, Yoshino T, Okuyama Y, Fujita T, Ohtani-Fujita N, Matsukawa Y, Tokino T, Yamagishi H, Oka T, Nomura H, Sakai T. Bu-tyrate activates the EAF1/Cipl gene promoter through Spl sites in a p53-negative human colon cancer cell line. J Biol Chem 1997; 272: 22199–206.
  • Moore WEC, Holdeman LV, Smibert RM, et al. Bacteriology of experimental gingivitis in young adult humans. Infect Immun 1982; 38: 651–67.
  • Botta GA, Radin L, Costa A, Schito G, Blasi G. Gas-liquid chromatography of the gingival fluid as an aid in periodontal diagnosis. J Periodont Res 1985; 20: 450–7.
  • Singer R, Bucker B. Butyrate and propionate: important components of toxic dental plaque extracts. Infect Immun 1981; 32: 458–63.
  • Fine DH, Mandel ID. Indications of periodontal disease activity: an evaluation. J Clin Periodontol 1986; 13: 533–46.
  • Niederman R, Zang J, Kashket S. Short-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammation. Crit Rev Oral Biol Med 1997; 8: 269–90.
  • Naleway C, Chou H, Manos T, Goodman C, Robinson P, Singer R, 1989. Assessment of the potential relationship be-tween levels of short chained fatty acids found in subgingival plaque and periodontal health. J Dent Res 68 (special issue): abstr. 121
  • Pollanen MT, Overman DO, Salonen A. Bacterial metabolites sodium butyrate and propionate inhibit epithelial growth in vitro. J Periodont Res 1997; 32: 326–34.
  • Kurita-Ochiai T, Ochiai K, Fukushima K, 1998 Volatile fatty acid, metabolic by-product of periodontopathic bacteria, in-duces apoptosis in WEHI231 and RAJI B lymphoma cells and splenic B cells, Infect Immun 2587–94
  • Sorkin BC, Niederman R. Short chain carboxylic acids de-crease human gingival keratinocyte proliferation and increase apoptosis and necrosis. J Clin Periodontol 1998; 25: 311–5.
  • Tse CS, Williams DH. Inhibition of human endothelial cell proliferation in vitro in response to n-butyrate and propi-onate. J Periodont Res 1992; 27: 506–10.
  • Kurita-Ochiai T, Fukushima K, Ochiai K. Volatile fatty acids, metabolic by-products of periodontopathic bacteria, inhibit lymphocyte proliferation and cytokine production. J Dent Res 1995; 74: 1367–73.
  • Kurita-Ochiai T, Fukushima K, Ochiai K. Butyric acid-in-duced apoptosis of murine thymocytes, splenic T cells, and human Jurkat T cell. Infect Immun 1997; 65: 35–41.
  • Kurita-Ochiai T, Fukushima K, Ochiai K. Lipopolysaccha-ride stimulates butyric acid-induced apoptosis in human pe-ripheral blood mononuclear cells. Infect Immun 1999; 67: 22–9.
  • Rotstein OD. Interactions between leukocytes and anaerobic bacteria in polymicrobial surgical infections. Clin Infect Dis 1993; 16 (Suppl 4): S190–4.
  • Rotstein OD, Vittorini T, Kao J, McBumey ME, Nasmith PE, Grinstein S. A soluble bacteroides by-product impairs phagocytosis killing of Escherichia coli by neutrophils. Infect Immun 1989; 57: 745–53.
  • Tonetti M, Eftimiadi C, Damiani G, Buffa D, Botta GA. Short chain fatty acids present in periodontal pockets may play a role in human periodontal diseases. J Periodont Res 1987; 22: 190–1.
  • Eftimiadi C, Tonetti M, Cavallero A, Sacco O, Rossi GA. Short chain fatty acids produced by anaerobic bacteria inhibit phagocytosis by human lung phagocytes. J Infect Dis 1990; 161: 138–42.
  • Rotstein OD, Nasmith PE, Grinstein S. pH-deppendent im-pairment of the neutrophil respiratory burst by the Bac-teroides by-product succinate. Clin Invest Med 1988; 11: 259–65.
  • Rosenthal GA, Levy G, Rotstein OD. Induction of macrophage procoagulant activity by Bacteroides fragilis. In-fect Immun 1989; 57: 338–43.
  • Bentley R, Meganathan R. Biosinthesis of vitamin K (menaquinone) in bacteria. Microbiol Rev 1982; 46: 241–80.
  • Collins MD, Jones D. Distribution of isoprenoid quinone structural types in bacteria and their taxonomic implications. Microbiol Rev 1981; 4: 316–54.
  • Taber H. Functions of vitamin K2 in microorganisms. In: Suttie JW, ed. Vitamin K metabolism and vitamin K depen-dent proteins. Baltimore: University Park Press, 1980: 177–87.
  • Conly JM, Stein RT. The production of menaquinones (vita-min K2) by intestinal bacteria and their role in maintaining coagulation homeostasis. Prog Food Nutr Sci 1992; 16: 307–43.
  • Conly JM, Stein RT. Quantitative and qualitative measure-ments of K vitamins in human intestinal contents. Am J Gastroenterol 1992; 87: 311–6.
  • Ramotar K, Conly JM, Chubb H, Louie TJ. Production of menaquinones by intestinal anaerobes. J Infect Dis 1984; 150: 213–8.
  • Conly JM, Stein RT. Are bioactive menaquinones (vitamin K2) liberated from bacteria into the extracellular milieu. Clin Invest Med (Supplement) 1990; 13: B60.
  • Hollander R, Mannheim W. Characterization of hemophilic and related bacteria by their respiratory quinones and cy-tochromes. Int Syst Bacteriol 1975; 25: 102–7.
  • Saiki I, Tokushima Y, Nishimura K, Azuma I. Macrophage activation with ubiquinones and their related compounds in mice. Int Vitamin Nutr Res 1983; 53: 312–20.
  • Block LH, Georgopoulos A, Mayer P, Drews J. Nonspecific resistance to bacterial infections. Enhancement by Ubi-quinone 8. J Exp Med 1978; 148: 1228–40.
  • Block LH, Georgopoulos A, Biemesderfer D, Herzog C, Kashgarian M, Sitaramam V. Ubiquinone-8 stimulate phago-cytosis in macrophages by modulation of the kinetics of the Fc receptor. J Infect Dis 1986; 153: 209–16.
  • Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Md 1994; 15 (Supplement): 241–8.