Effects of metronidazole on growth of Gardnerella vaginalis ATCC 14018, probiotic Lactobacillus rhamnosus GR-1 and vaginal isolate Lactobacillus plantarum KCA

References

• Fredricks DN, Fiedler TL, Marrazzo JM. Molecular identification of bacteria associated with bacterial vaginosis. N Engl J Med 2005; 353: 1899–911
   PubMed Web of Science ®Google Scholar
• Burton JP, Devillard E, Cadieux PA, Hammond JA, Reid G. Detection of Atopobium vaginae in postmenopausal women by cultivation-independent methods warrants further investigation. J Clin Microbiol 2004; 42: 1829–31
   Web of Science ®Google Scholar
• Ferris DG, Nyirjesy P, Sobel JD, Soper D, Pavletic A, Litaker MS. Over-the-counter antifungal drug misuse associated with patient-diagnosed vulvovaginal candidiasis. Obstet Gynecol 2002; 99: 419–25
   PubMed Web of Science ®Google Scholar
• Allsworth JE, Peipert JF. Prevalence of bacterial vaginosis: 2001–2004 National Health and Nutrition Examination Survey data. Obstet Gynecol 2007; 109: 114–20
   PubMed Web of Science ®Google Scholar
• Sewankambo N, Gray RH, Wawer MJ, Paxton L, McNaim D, Wabwire-Mangen F, et al. HIV-1 infection associated with abnormal vaginal flora morphology and bacterial vaginosis. Lancet 1997; 350: 546–50
   PubMed Web of Science ®Google Scholar
• Koumans EH, Kendrick JS. CDC Bacterial Vaginosis Working Group. Preventing adverse sequelae of bacterial vaginosis: a public health program and research agenda. Sex Transm Dis 2001; 28: 292–7
   PubMed Web of Science ®Google Scholar
• Cherpes TL, Meyn LA, Krohn MA, Lurie JG, Hillier SL. Association between acquisition of herpes simplex virus type 2 in women and bacterial vaginosis. Clin Infect Dis 2003; 37: 319–25
   PubMed Web of Science ®Google Scholar
• Leitich H, Kiss H. Asymptomatic bacterial vaginosis and intermediate flora as risk factors for adverse pregnancy outcome. Best Pract Res Clin Obstet Gynaecol 2007; 21: 375–90
   PubMed Web of Science ®Google Scholar
• McGregor JA, Larson PG. King Holmes, bacterial vaginosis and women and babies. Int J Gynecol Obstet 1999; 67(Suppl 1)S9–S11
   Google Scholar
• Austin MN, Beigi RH, Meyn LA, Hillier SL. Microbiologic response to treatment of bacterial vaginosis with topical clindamycin or metronidazole. J Clin Microbiol 2005; 43: 4492–7
   PubMed Web of Science ®Google Scholar
• Bradshaw CS, Morton AN, Hocking J, Garland SM, Morris MB, Moss LM, et al. High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence. J Infect Dis 2006; 193: 1478–86
   PubMed Web of Science ®Google Scholar
• Eschenbach DA. Bacterial vaginosis: resistance, recurrence, and/or reinfection?. Clin Infect Dis 2007; 44: 220–1
   PubMed Web of Science ®Google Scholar
• Schwebke JR, Desmond RA. A randomized trial of the duration of therapy with metronidazole plus or minus azithromycin for treatment of symptomatic bacterial vaginosis. Clin Infect Dis 2007; 44: 213–19
   PubMed Web of Science ®Google Scholar
• Thomas KK, Sanchez S, Garcia PJ, Holmes KK. Why do different criteria for ‘cure’ yield different conclusions in comparing two treatments for bacterial vaginosis?. Sex Transm Dis 2005; 32: 526–30
   Web of Science ®Google Scholar
• Hillier SL, Holmes KK. Bacterial vaginosis. Sexually transmitted diseases3rd edn, KK Holmes, PF Sparling, P-M Mardh, SM Lemon, WE Stamm, P Piot, et al. McGraw Hill, New York 1999; 563–86
   Google Scholar
• Sobel JD, Ferris D, Schwebke J, Nyirjesy P, Wiesenfeld HC, Peipert J, et al. Suppressive antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosis. Am J Obstet Gynecol 2006; 194: 1283–9
   PubMed Web of Science ®Google Scholar
• Anukam KC, Osazuwa EO, Ahonkhai I, Ngwu M, Osemene G, Bruce AW. Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial. Microbes Infect 2006; 8: 1450–4
   PubMed Web of Science ®Google Scholar
• Anukam KC, Osazuwa E. Osemene GI, Ehigiagbe F, Bruce AW, Reid G. Clinical study comparing probiotic Lactobacillus GR-1 and RC-14 with metronidazole vaginal gel to treat symptomatic bacterial vaginosis. Microbes Infect 2006; 8: 2772–6
   PubMed Web of Science ®Google Scholar
• Geshnizgani AM, Onderdonk AB. Defined medium simulating genital tract secretions for growth of vaginal microflora. J Clin Microbiol 1992;1323–6.
   Web of Science ®Google Scholar
• Simoes JA, Aroutcheva AA, Shott S, Faro S. Effect of metronidazole on the growth of vaginal lactobacilli in vitro. Infect Dis Obstet Gynecol 2001; 9: 41–5
   PubMedGoogle Scholar
• Swidsinski A, Mendling W, Loening-Baucke V, Ladhoff A, Swidsinski S, Hale LP, et al. Adherent biofilms in bacterial vaginosis. Obstet Gynecol 2005; 106(5 Pt 1)1013–23
   Web of Science ®Google Scholar
• Austin MN, Meyn LA, Hillier SL. Susceptibility of vaginal bacteria to metronidazole and tinidazole. Anaerobe 2006; 12: 227–30
   PubMed Web of Science ®Google Scholar
• Keane FE, Ison CA, Taylor-Robinson D. A longitudinal study of the vaginal flora over a menstrual cycle. Int J STD AIDS 1997; 8: 489–94
   PubMed Web of Science ®Google Scholar
• Nyirjesy P, McIntosh MJ, Gattermeir DJ, Schumacher RJ, Steinmetz JI, Joffrion JL. The effects of intravaginal clindamycin and metronidazole therapy on vaginal lactobacilli in patients with bacterial vaginosis. Am J Obstet Gynecol 2006; 194: 1277–82
   Web of Science ®Google Scholar
• Saunders S, Bocking A, Challis J, Reid G. Effect of Lactobacillus challenge on Gardnerella vaginalis biofilms. Colloids Surf B Biointerfaces 2007; 55: 138–42
   PubMed Web of Science ®Google Scholar
• Atassi F, Brassart D, Grob P, Graf F, Servin AL. Lactobacillus strains isolated from the vaginal microbiota of healthy women inhibit Prevotella bivia and Gardnerella vaginalis in coculture and cell culture. FEMS Immunol Med Microbiol 2006; 48: 424–32
   Google Scholar
• Sethi S, Das A, Sharma M. Inhibition of Gardnerella vaginalis by lactobacilli. Int J Gynaecol Obstet 2006; 93: 158–9
   Web of Science ®Google Scholar
• Forney LJ, Foster JA, Ledger W. The vaginal flora of healthy women is not always dominated by Lactobacillus species. J Infect Dis 2006; 194: 1468–9
   PubMed Web of Science ®Google Scholar
• Davis B, Glover DD, Larsen B. Analysis of metronidazole penetration into vaginal fluid by reverse-phase high-performance liquid chromatography. Am J Obstet Gynecol 1984; 149: 802–3
   Web of Science ®Google Scholar
• Decena DC, Co JT, Manalastas RM, Jr, Palaypayon EP, Padolina CS, Sison JM, et al. Metronidazole with Lactacyd vaginal gel in bacterial vaginosis. J Obstet Gynaecol Res 2006; 32: 243–51
   PubMed Web of Science ®Google Scholar