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Autoimmunity Volume 35, 2002 - Issue 8
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Research Article

Frequency and Significance of Antibodies to Soluble Liver Antigen/Liver Pancreas in Variant Autoimmune Hepatitis

Albert J. Czaja Division of Gastroenterology and Hepatology, Mayo Clinic and Mayo Foundation, 200 First Street S.W. Rochester, MN 55905, USA
,
Zakera Shums INOVA Diagnostics, San Diego, CA, USA
&
Gary L. Norman INOVA Diagnostics, San Diego, CA, USA
Pages 475-483 | Published online: 07 Jul 2009

  • Czaja, A.J. (1996) "The variant forms of autoimmune hepatitis". Ann. Intern. Med. 125, 588-598.
  • Czaja, A. J. (1998) "Frequency and nature of the variant syndromes of autoimmune liver disease". Hepatology 28, 360-365.
  • Czaja, A. J. (1991) "Variant forms of autoimmune hepatitis", Curr. Gastroenterol. Rep. 1, 63-70.
  • Ben-Ari, Z. and Czaja, A.J. (2001) "Autoimmune hepatitis and its variant syndromes", Gut 49, 589-594.
  • Woodward, J. and Neuberger, J. (2001) "Autoimmune overlap syndromes", Hepatology 33, 994-1002.
  • Czaja, A.J., Carpenter, H.A., Santrach, P.J., Moore, S.B. and Homburger, H.A. (1993) "The nature and prognosis of severe cryptogenic chronic active hepatitis", Gastroenterology 104, 1755-1761.
  • Kenny, R.P., Czaja, A.J., Ludwig, J. and Dickson, E.R. (1986) "Frequency and significance of antimitochondrial antibodies in severe chronic active hepatitis". Dig. Dis. Sci. 31, 705-711.
  • Duclos-Vallee, J-C., Hadengue, A., Ganne-Carrie, N., Robin, E., Degott, C. and Erlinger, S. (1995) "Primary biliary cirrhosisautoimmune hepatitis overlap syndrome: corticoresistance and effective treatment with cyclosporine A", Dig. Dis. Sci. 40, 1069-1073.
  • Chazouilleres, O., Wendum, D., Serfaty, L., Montebault, S., Rosmorduc, O. and Poupon, R. (1998) "Primary biliary cirrhosisautoimmune hepatitis overlap syndrome: clinical features and response to therapy", Hepatology 28, 296-301.
  • Lohse, A.W., Meyer zum Buschenfelde, K.H., Kanzler, F.B., Gerken, G. and Dienes, H. P (1999) "Characterization of the overlap syndrome of primary biliary cirrhosis (PBC) and autoimmune hepatitis: evidence for it being a hepatitic form of PBC in genetically susceptible individuals", Hepatology 29, 1078-1084.
  • Perdigoto, R., Carpenter, H.A. and Czaja, A.J. (1992) "Frequency and significance of chronic ulcerative colitis in severe corticosteroid-treated autoimmune hepatitis", J. Hepatol. 14, 325-331.
  • Rabinovitz, M., Demetris, A.J., Bou-Abboud, C.F. and Van Thiel, D.H. (1992) "Simultaneous occurrence of primary sclerosing cholangitis and autoimmune chronic active hepatitis in a patient with ulcerative colitis", Din. Dis. Sci. 37, 1606-1611.
  • Boberg, K.M., Fausa, O., Haaland, T., Holter, E., Mellbye, O.J., Spurkland, A., et al. (1996) "Features of autoimmune hepatitis in primary sclerosing cholangitis: an evaluation of 114 primary sclerosing cholangitis patients according to a scoring system for the diagnosis of autoimmune hepatitis", Hepatology 23, 1369-1376.
  • Gohlke, F., Lohse, A.W., Dienes, H.P. Lohr, H., Marker-Hermann, E., Gerken, G., et al. (1996) "Evidence for an overlap syndrome of autoimmune hepatitis and primary sclerosing cholangitis", J. Hepatol. 24, 699-705.
  • Luketic, V.A.C., Gomez, D.A., Sanyal, A.J. and Shiffman, M.L. (1997) "An atypical presentation for primary sclerosing cholangitis", Dig. Dis. Sci. 42, 2009-2016.
  • McNair, A.N.B., Moloney, M., Portmann, B.C., Williams, R. and McFarlane, I.G. (1998) "Autoimmune hepatitis overlapping with primary sclerosing cholangitis in S cases", Am. J. Gastroenterol. 93, 777-784.
  • Ben-Ari, Z., Dhillon, A.P. and Sherlock, S. (1993) "Autoimmune cholangiopathy: part of the spectrum of autoimmune chronic active hepatitis", Hepatology 18, 10-15.
  • Colombato, L.A., Alvarez, F., Cote, J. and Huet, P.M. (1994) "Autoimmune cholangiopathy: the result of primary biliary cirrhosis and autoimmune hepatitis", Gastroenterology 107, 1839-1843.
  • Michieletti, P. Wanless, I.R., Katz, A., Scheuer, P.J., Yeaman, S.J., Bassendine, M.F., er dl. (1994) "Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis". Gut 35, 260-265.
  • Taylor, S.L., Dean, P.J. and Riely, C.A. (1994) "Primary autoimmune cholangitis: an alternative to antimitochondrial antibody-negative primary biliary cirrhosis", Am. J. Clin, Pathol. 18, 91-99.
  • Goodman, Z.D., McNally, P.R., Davis, D.R. and Ishak, K.G. (1995) "Autoimmune cholangitis: a variant of primary biliary cirrhosis. Clinicopathologic and serologic correlations in 200 cases", Dig. Dis. Sci. 40, 1232-1242.
  • Sherlock, S. (1998) "Autoimmune cholangitis: a unique entity?". Mayo Clin. Proc. 73, 184-190.
  • Czaja, A.J., Carpenter, H.A., Santrach, P.J. and Moore, S.B. (2000) "Autoimmune cholangitis within the spectrum of autoimmune liver disease", Hepatology 31, 1231-1238.
  • Czaja, A.J. (1993) "Chronic active hepatitis: the challenge for a new nomenclature". Ann. Intern. Med. 119, 510-517.
  • Heathcote, J. (2002) "Variant syndromes of autoimmune hepatitis", Clin. Liver. Dis. 6, 381-396.
  • Czaja, A.J. and Carpenter, H.A. (2001) "Autoimmune hepatitis with incidental histologic features of bile duct injury", Hepatology 34, 659-665.
  • Czaja, A.J., Santrach, P.J. and Moore, S.B. (2001) "Shared genetic risk factors in autoimmune liver disease", Dig. Dis. Sci. 46, 140-147.
  • Carpenter, H.A. and Czaja, A.J. (2002) "The role of histological evaluation in the diagnosis and management of autoimmune hepatitis and its variants". Clin. Liver Dis. 6, 397-417.
  • Baeres, M., Herkel, J., Czaja, A.J., Wies, I., Kanzler, S., Cancado, E.L.R., et al. (2002) "Establishment of standardized SLA/LP immunoassays: specificity for autoimmune hepatitis, worldwide occurrence and clinical characteristics". Gut 51, 259-264.
  • Czaja, A.J., Donaldson, P.T. and Lohse, A.W. (2002) "Antibodies to soluble liver antigen/liver pancreas and HLA risk factors in type 1 autoimmune hepatitis", Am. J. Gastroenterol. 97, 413-419.
  • Alvarez, F., Berg, P.A., Bianchi, F.B., Bianchi, L., Burroughs, A.K., Cancado, E.L., et al. (1999) "International Autoimmune Hepatitis Group report: review of criteria for diagnosis of autoimmune hepatitis". J. Hepatol. 31, 929-938.
  • Czaja, A.J. and Freese, D.K. (2002) "Diagnosis and treatment of autoimmune hepatitis", Hepatology 36, 479-497.
  • Czaja, A.J., Strettell, M.D.J., Thomson, L.J., Santrach, P.J., Moore, S.B., Donaldson, P.T. et al. (1997) "Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis". Hepatology 25, 317-323.
  • Czaja, A.J., Cassani, F., Cataleta, M., Valentini, P. and Bianchi, F.B. (1996) "Frequency and significance of antibodies to actin in type 1 autoimmune hepatitis", Hepatology 24, 1068-1073.
  • Czaja, A.J., Carpenter, H.A. and Manns, M.P. (1993) "Antibodies to soluble liver antigen. P450IID6. and mitochondrial complexes in chronic hepatitis", Gastroenterology 105, 1522-1528.
  • Czaja, A.J., Nishioka, M., Morshed, S.A. and Hachiya, T. (1994) "Patterns of nuclear immunofluorescence and reactivities to recombinant nuclear antigens in autoimmune hepatitis", Gastroenterology 107, 200-207.
  • Czaja, A.J., Cassani, F., Cataleta, M., Valentini, P. and Bianchi, F.B.(1997) "Antinuclear antibodies and patterns of nuclear immunofluorescence in type 1 autoimmune hepatitis", Dig. Dis. Sci. 42, 1688-1696.
  • Homburger, H.A., Cahen, Y.D., Griffiths, J. and Jacob, G.L. (1998) "Detection of antinuclear antibodies. Comparative evaluation of enzyme immunoassay and indirect immunofluorescence methods", Arch. Pathol. Lab. Med. 122, 993-999.
  • Czaja, A.J. and Homburger, H.A. (2001) "Autoantibodies in liver disease", Gastroenterology 120, 239-249.
  • Czaja, A.J., Manns, H.P. and Homburger, H.A. (1992) "Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis", Gastroenterology 103, 1290-1295.
  • Czaja, A.J. (1999) "Drug therapy in the management of type 1 autoimmune hepatitis", Drugs 57, 49-68.
  • Summerskill, W.H.J., Korman, M.G., Ammon, H.V. and Baggenstoss, A.H. (1975) "Prednisone for chronic active liver disease: dose titration. standard dose, and combination with azathioprine compared", Gut 16, 876-883.
  • Czaja, A.J., Wolf, A.M. and Baggenstoss, A.H. (1981) "Laboratory assessment of severe chronic active liver disease (CALD): correlation of serum transaminase and gamma globulin levels with histologic features", Gastroenterology 80, 687-692.
  • Czaja, A.J., Menon, K.V.N. and Carpenter, H.A. (2002) "Sustained remission after corticosteroid therapy for type 1 autoimmune hepatitis: a retrospective analysis", Hepatology 35, 890-897.
  • Czaja, A.J. and Carpenter, H.A. (1993) "Sensitivity, specificity and predictability of biopsy interpretations in chronic hepatitis", Gastroenterology 105, 1824-1832.
  • Wies, I., Brunner, S., Henninger, J., Herkel, J., Meyer zum Buschenfelde, K.H. and Lohse, A.W. (2000) "Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis", Lancet 355, 1510-1515.
  • Kanzler, S., Weidemann, C., Gerken, G., Lohr, H.F., Galle, P.R., Meyer zum Buschenfelde, K.H., et al. (1999) "Clinical significance of autoantibodies to soluble liver antigen in autoimmune hepatitis". J. Hepatol. 31, 635-640.
  • Kernebeck, T., Lohse, A.W. and Grotzinger, J. (2001) "A bioinformatical approach suggests the function of the autoimmune hepatitis target soluble liver antigen/liver pancreas". Hepatology 34, 230-233.
  • Gelpi, C., Sontheimer, E.J. and Rodriguez-Sanchez, J.L. (1992) "Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion". Proc. Natl. Acad. Sci. USA 89, 9739-9743.
  • Costa, M., Rodriques-Sanchez, J.L., Czaja, A.J. and Gelpi, C. (2000) "Isolation and characterization of cDNA encoding the antigenic protein of the human tRNA(Ser)Sec complex recognized by autoantibodies from patients with type 1 autoimmune hepatitis", Clin. Exp. Immunol. 121, 364-374.
  • Volkmann, M., Martin, L., Baurle, A., Heid, H., Strassburg, C.P. Trautwein. C., et al. (2001) "Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically reacts with sera from patients with autoimmune hepatitis", Hepatalogy 33, 591-596.
  • Czaja, A.J. (1999) "Behavior and significance of autoantibodies in type 1 autoimmune hepatitis", J. Hepatol. 30, 394-401.
  • Czaja, A.J. and Carpenter, H.A. (1996) "Validation of a scoring system for the diagnosis of autoimmune hepatitis". Dig. Dis. Sci. 41, 305-314.
  • Ma, Y., Okamoto, M., Thomas, M.G., Bogdanos, D.P. Lopes, A.R., Portmann, B., et al. (2002) "Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease", Hepatology 35, 658-664.
  • McFarlane, I.G., Hegarty, J.E., McSorley, C.G., McFarlane, B.M. and Williams, R. (1984) "Antibodies to liver-specific protein predict outcome of treatment withdrawal in autoimmune chronic active hepatitis", Lancet 2, 954-956.
  • Czaja, A.J., Pfeifer, K.D., Decker, R.H. and Vallari, A.S. (1996) "Frequency and significance of antibodies to asialoglycoprotein receptor in type 1 autoimmune hepatitis", Dig. Dis. Sci. 41, 1733-1740.
  • Czaja, A.J. (2001) "Understanding the pathogenesis of autoimmune hepatitis", Am. J. Gastroenterol. 96, 1224-1231.

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