- Gepts, W. (1965) "Pathologic anatomy of the pancreas in juvenile diabetes raellitus", Diabetes 14, 619-633.
- Junker, K., Egeberg, J., Kromann, H. and Nerup, I. (1977) "An autopsy study of the islets of Langerhans in acute onset juvenile diabetes mellitus", Acta Pathologien Et Micmbiologica Scandinavica Section a Pathology 85, 699-706.
- Nerup, J., Mandrup-Poulsen, T., Helqvist, S., Andersen, H.U., Pociot, F., Reimers, J.I., Cuartero, B.C., Karlsen, A.E., Bjerre, U. and Lorenzen, T. (1994) "Qn the pathogenesis of IDDM", Diabetologia 37(Suppl. 2), S82-S89.
- Gotfredsen, C.F., Buschard, K. and Frandsen, E.K. (1985) "Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals", Diabetologia 28, 933-935.
- Vlahos, W.D., Seemayer, T.A. and Yale, J.F. (1991) "Diabetes prevention in BB rats by inhibition of endogenous insulin secretion", Metabolism: Clinical and Experimental 40, 825-829.
- Gottlieb, P.A., Handler, E.S., Appel, M.C., Greiner, D.L., Mordes, J.P. and Rossini, A.A. (1991) "Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats", Diabetologia 34, 296-300.
- Bertrand, S., De-Paepe, M., Vigeant, C. and Yale, J.F. (1992) "Prevention of adoptive transfer in BB rats by prophylactic insulin treatment", Diabetes 41, 1273-1277.
- KoIb, H., Worz-Pagenstert, U., Kleemann, R., Rothe, H., Rowsell, P., Rastegar, S. and Scott, F.W. (1997) "Insulin therapy of prediabetes suppresses THl associated gene expression in BB rat pancreas", Autoimmunity 26, 1-6.
- Stevens, R.B., Sutherland, D.E., Ansite, J.D., Saxena, M., Rossini, T.J., Levay-Young, B.K., Hering, BJ. and Mills, C.D. (1997) "Insulin down-regulates the inducible nitric oxide synthase pathway: nitric oxide as cause and effect of diabetes?', Journal of Immunology 159, 5329-5335.
- Atkinson, M.A., Maclaren, N.K. and Luchetta, R. (1990) "Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy", Diabetes 39, 933-937.
- Iansen, A., Rosmalen, J.G., Homo-Delarche, F., Dardenne, M. and Drexhage, H.A. (1996) "Effect of prophylactic insulin treatment on the number of ER-MP23+ macrophages in the pancreas of NOD mice. Is the prevention of diabetes based on beta-cell rest?", Journal of Autoimmunity 9, 341-348.
- Anastasi, E., Dotta, F., Tiberti, C., Vecci, E., Ponte, E. and Di-Mario, U. (1999) "Insulin prophylaxis down-regulates islet antigen expression and islet autoimmunity in the low-dose STZ mouse model of diabetes", Autoimmunity 29, 249-256.
- Nakhooda, A.F., Like, A.A., Chappel, C.I., Wei, C.N. and Marliss, E.B. (1978) "The spontaneously diabetic Wistar rat (the "BB" rat). Studies prior to and during development of the overt syndrome", Diabetologia 14, 199-207.
- Logothetopoulos, J., Valiquette, N., Madura, E. and Cvet, D. (1984) "The onset and progression of pancreatic insulitis in the overt, spontaneously diabetic, young adult BB rat studied by pancreatic biopsy", Diabetes 33, 33-36.
- Svenningsen, A., Dyrberg, T, Markholst, H., Binder, C. and Lernmark, A. (1986) "Insulin release and pancreatic insulin is reduced in young prediabetic BB rats", Acta Endocrinologica 112, 367-371.
- Bone, A.J., Walker, R., Dean, B.M., Baird, I.D. and Cooke, A. (1987) "Pre-diabetes in the spontaneously diabetic BB/E rat: pancreatic infiltration and islet cell proliferation", Acta Endocrinologica 115, 447-454.
- Christensen, U., Sparre, T, Cooke, A., Andersen, H., MandrupPoulsen, T. and Nerup, J. (1998) "Syngeneic islet transplantation in prediabetic BB-DP rats-a synchronized model for studying betacell destruction during the development of IDDM", Autoimmunity 28,91-107.
- Mordes, J.P., Bortell, R., Groen, H., Geuberski, D., Rossini, A.A. and Greiner, D.L. (2001) "Autoimmune diabetes mellitus in the BB rat", In: Sima, A.A.A. and Shafrir, E., eds, Frontiers in Animal Diabetes Research (Harwood Academic Publishers, Reading) Vol. 2, pp 1-41.
- Buschard, K., Brogren, C.H., Röpke, C. and Rygaard, J. (1988) "Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific, BB rat monoclonal autoantibody IC2", APMIS 96, 342-346.
- Schroder, D., Ratke, M., Bauer, U.C., Kloting, I., Ziegler, B. and Schmidt, S. (2002) "Prophylactic insulin treatment of diabetes-prone BB/OK rats by application of a sustained release insulin implant", Autoimmunity 35, 143-153.
- McCulloch, O.K., Barmeier, H., Neifing, J.L. and Palmer, J.P. (1991) "Metabolic state of the pancreas affects end-point titre in the islet cell antibody assay", Diabetologia 34, 622-625.
- Christensen, U.B., Larsen, P.M., Fey, S.J., Andersen, H.U., Nawrocki, A., Sparre, T., Mandrup-Poulsen, T. and Nerup, J. (2000) "Islet protein expression changes during diabetes development in islet syngrafts in BB-DP rats and daring rejection of BB-DP islet allografts", Autoimmunity 32, 1-15.
- Bninstedt, J., Nielsen, J.H., Lernmark, U+0226. and The Hagedorn Study Group (1984) "Isolation of islets from mice and rats", In: Lamer, J. and Pohl, S.L., eds, Methods in Diabetes Research, (Laboratory Methods, Part C) (Wiley, New York) Vol. 1, pp 254-288.
- Weringer, EJ. and Like, A.A. (1988) "Identification of T cell subsets and class I and class D antigen expression in islet grafts and pancreatic islets of diabetic BioBreeding/Worcester rats", American Journal of Pathology 132, 292-303.
- Korsgren, O., Jansson, L., Sandier, S. and Andersson, A. (1990) "Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background", Journal of Clinical Investigation 86, 2161-2168.
- Butler, L., Guberski, D.L. and Like, A.A. (1983) "Genetic analysis of the Bb-W diabetic rat", Canadian Journal of Genetics and Cytology 25, 7-15.
- Green, L.C., Wagner, D.A., Glogowski, I., Skipper, P.L., Wishnok, J.S. and Tannenbaum, S.R. (1982) "Analysis of nitrate, nitrite, and (15N)nitrate in biological fluids", Analytical Biochemistry 126, 131-138.
- Nielsen, K., Karlsen, A.E., Decken, M., Madsen, O.D., Serup, P., Mandrup-Poulsen, T. and Nerup, J. (1999) "Beta-cell maturation leads to in vitro sensitivity to cytotoxins", Diabetes 48,2324-2332.
- Tanaka, T., Masuko, T., Yagita, H., Tamura, T. and Hashimoto, Y. (1989) "Characterization of a CD3-like rat T cell surface antigen recognized by a monoclonal antibody", Journal of Immunology 142,2791-2795.
- Shimada, S., Shibagaki, N., Tanaka, T., Kubota, Y, Hashimoto, Y. and Taraaki, K. (1992) "Identification of an equivalent to murine Thy-1+ dendritic epidermal cells in the rat epidermis", Journal of Dermatological Science 3, 68-71.
- Elbe, A., Kilgus, O., Hunig, T. and Stingl, G. (1994) "T-cell receptor diversity in dendritic epidermal T cells in the rat", Journal of Investigative Dermatology 102, 74-79.
- Pinheiro, J.C. and Bates, D.M. (2000) Mixed Effects Models in S andS-plus, 1st Ed. (Springer, Berlin).
- Corbett, I.A., Wang, J.L., Hughes, I.H., Wolf, B.A., Sweetland, M.A., Lancaster, J.R. and McDaniel, M.L. (1992) "Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction", Biochemical Journal 287(Pt 1), 229-235.
- Andersen, H.U., Larsen, P.M., Fey, S.J., Karlsen, A.E., MandrupPoulsen, T. and Nerup, J. (1995) "Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide", Diabetes 44, 400-407.
- Finegood, D.T., Scaglia, L. and Bonner-Weir, S. (1995) "Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model", Diabetes 44, 249-256.
- Diabetes Prevention Trial-Type 1 Diabetes Study Group(2002) "Effects of insulin in relatives of patients with type 1 diabetes mellitus", New England Journal of Medicine 346, 1685-1691.
- Gotfredsen, C.F. and Buschard, K. (1986) "Early prophylactic insulin treatment of diabetes prone BB Wistar rats reduces the incidence/serverity of diabetes", Acta Endocrinologica Supplementum 112, 3.
Prophylactic Insulin Treatment of Syngeneically Transplanted Pre-diabetic BB-DP Rats
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.