Yersinia Enterocolitica O:3 Isolated from Patients with or without Reactive Arthritis Induces Polyclonal Activation of B Cells and Autoantibody Production In Vivo

References

• Leirisalo-Repo, M. and Suoranta, H. (1988) "Ten year follow-up study of patients with Yersinia arthritis", Arthritis Rheum. 31, 533–537.
   PubMed Web of Science ®Google Scholar
• Valtonen, V, Leirisalo, M., Pentikainen, P.J., Rasanen, T., Seppala, I., Larinkali, U., et al. (1985) "Triggering infections in reactive arthritis", Ann. Rheum. Dis. 44, 399–405.
   PubMed Web of Science ®Google Scholar
• Granfors, K. (1997) "Host-microbe interaction in HLA-B27-associated diseases", Ann Med. 29, 153–157.
   PubMed Web of Science ®Google Scholar
• Granfors, K. (1998) "Host-microbe interaction in reactive arthritis: does HLA-B27 have a direct effect?", J. Rheum. 25, 1659–1661.
   PubMed Web of Science ®Google Scholar
• Ikeda, M. and Yu, D.T.Y. (1998) "The pathogenesis of HLA-B27 arthritis: role of HLA-B27 in bacterial defense", Am. J. Med. Sci. 316, 257–263.
   PubMed Web of Science ®Google Scholar
• Taurog, J.D. (1998) "Arthritis in HLA-B27 transgenic animals", Am. J. Med. Sci. 316, 250–256.
   PubMed Web of Science ®Google Scholar
• Toivanen, P. and Toivanen, A. (1994) "Does Yersinia induce autoimmunity?", Int. Arch. Allergy Immunol. 104, 107–111
   PubMed Web of Science ®Google Scholar
• Wuorela, M., Jalkanen, S., Kirveskari, J., Laitio, P. and Granfors, K. (1997) "Yersinia enterocolitica serotype 0:3 alters the expression of serologic HLA-B27 epitopes on human monocytes", Infect. Immun. 65, 2060–2066.
   PubMed Web of Science ®Google Scholar
• Granfors, K., Merilahti-Palo, R., Luukkainen, R., Mottonen, T. and Lahesmaa, R. and Probst, P., et al. (1998) "Persistence of Yersinia antigens in peripheral blood cells from patients with Yersinia enterocolitica 0:3 infection with or without reactive arthritis", Arthritis Rheum. 41, 855–862.
   PubMedGoogle Scholar
• Lahesmaa, R., Shurnik, M. and Toivanen, P. (1993) "Molecular mimicry: any role in the pathogenesis of spondyloarthropathies?", Immunol. Res. 12, 193–208.
   PubMed Web of Science ®Google Scholar
• Lahesmaa, R., Shanafelt, MC., Steinman, L. and Peltz, G. (1994) "Immunopathogenesis of humam inflamatory arthritis: lessons from Lyme and reactive arthritis", J. Infect. Dis. 170, 978–985.
   PubMed Web of Science ®Google Scholar
• Medeiros, B.M.M., Costa, A.M., Araujo, P.M.F. and Falcdo, D.P. (1995) "Occurence of polyclonal B cell activation after experimen-tal infection with Yersinia enterocolitica 0:3", Contrib. Microbiol. Immunol. 13, 207–210.
   PubMedGoogle Scholar
• Crespo, A.M.C., Feed°, D.P., Aratijo, P.M.F. and Medeiros, B.M.M. (2002) "Effects of Yersinia enterocolitica 0:3 derivatives on B lymphocyte activation in vivo", Microbiol. Immunol. 46, 95–100.
   Google Scholar
• Gripenberg, M., Miettinen, A., Kurki, P. and Linder, E. (1978) "Humoral immune stimulation and antiepithelial antibodies in Yersinia infections", Arthritis Rheum. 21, 904–908.
   PubMed Web of Science ®Google Scholar
• Montplaisir, S., Gagne, M., Dubois, R., Gengoux, P. and Pelletier, M. (1979) "Brush border membrane antibodies in Yersinia infection and other diseases", Contrib. MicrobioL Immunol. 5, 351–358.
   PubMedGoogle Scholar
• Shenkman, L. and Bottone, E.J. (1981) "The occurrence of antibodies to Yersinia enterocolitica in thyroid diseases", In: Bottone, E.J., ed, Yersinia Enterocolitica (CRC Press, Boca Raton), pp. 135–44.
   Google Scholar
• Medeiros, B.M.M., Costa, A.M., Araujo, P.M.F. and Fala), D.P. (1997) "Association between polyclonal B cell activation and the presence of autoantibodies in mice infected with Yersinia enterocolitica 0:3", Braz. J. Med. Biol. Res. 30, 401–405.
   PubMed Web of Science ®Google Scholar
• Costa, A.M. (1995) Células esplenicas secretoras de imunoglobu-linas e anticorpos sericos em camundongos Swiss livres de patógenos especfficos inoculados corn Yersinia enterocolitica 0:3 ou derivados, 72 f. Master's dissertation in Immunology, Institut° de Biologia, UNICAMP, Campinas, Brazil (in Portuguese).
   Google Scholar
• Lowly, 0.H., Rosebrough, N.J., Farr, A.L. and Randall, R. (1951) "Protein measurement with the folin phenol reagent", J. Micro biol. Chem. 193, 265–275.
   Google Scholar
• Czerkinski, C.C., Nilsson, L.A., Nygren, H., Ouchterlony, 0. and Tarkowsi, A. (1983) "A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells", J. Immunol. Methods 65, 109–121.
   PubMed Web of Science ®Google Scholar
• Heinicke, E., Kumar, U. and Munoz, D.G. (1992) "Quantitative dot-blot assay for proteins using enhanced chemiluminescence", J. Immunol. Methods 152, 227–236.
   PubMed Web of Science ®Google Scholar
• Heeseman, J., Gross, V, Schimidt, N. and Laufs, R. (1986) "Immunochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia sp. Grown in calcium-deficient media", Infect. Immun. 54, 561–567.
   PubMed Web of Science ®Google Scholar
• Duane, L.P., William, H.A. and Smith, R.T. (1970) "The mitogenic effects of endotoxin and staphylococcal enterotoxin B on mouse spleen cells and human peripheral lymphocytes", J. Immunol. 105, 1453–1458.
   PubMed Web of Science ®Google Scholar
• Luo, G., Fan, J.L., Seetharamaiah, G.S., Desai, R.K., Dallas, J.S., Wagle, N., Doan, R., Niesel, D.W., Klimpel, G.R. and Prabhakar, B.S. (1993) "Immunization of mice with Yersinia enterocolitica leads to the induction of antithyrotropin receptor antibodies", J. Immunol. 151, 922–928.
   PubMed Web of Science ®Google Scholar
• Luo, G., Seetharamaiah, G.S., Niesel, D., Zhang, H., Peterson, J.W., Prabhakar, B.S. and Klimpel, G.R. (1994) "Purification and characterization of Yersinia enterocolitica envelope proteins which induce antibodies that react with human thyrotropin receptor", J. Immunol. 152, 2555–2561.
   PubMed Web of Science ®Google Scholar
• Zhang, H., Kaur, I., Niesel, D.W., Seetharamaiah, G.S., Peterson, J.W., Justement, L.B., Prabhakar, B.S. and Klimpel, G.R. (1996) "Yersinia enterocolitica envelope proteins that are crossreactive with the thyrotropin receptor (TSHR) also have B-cell mitogenic activity", J. Autoimmun. 9, 509 —516.
   Web of Science ®Google Scholar
• Di Genaro, M.S., Escudero, M.E., Munoz, E., Aguilera, C., Juarez, A., Scardapane, L. and Guzman, A.M.S. (1998) "Arthritogenicity of Yersinia enterocolitica 0:8 in hamsters: analysis of the immune response", Folia MicrobioL 43, 690–696.
   PubMed Web of Science ®Google Scholar
• Di Genaro, US., Escudeo, M.E., Velazquez, L., Munoz, E., Aguilera, C., Juarez, A., Scardapane, L. and Guzman, A.M.S. (1997) "Humoral immune response in Yersinia enterocolitica 0:5 induced arthritis in hamsters", MicrobioL Immunol. 41, 615–620.
   PubMed Web of Science ®Google Scholar
• Berneman, A., Ternynck, T. and Avrameas, S. (1992) "Natural mouse IgG reacts with self antigens including molecules involved in the immune response", Eur J. Immunol. 22, 625–633.
   PubMed Web of Science ®Google Scholar
• Toivanen, A., Merilahti-Palo, R., Gripenberg, C., Lahesmaa-Rantala, R., Soderstrom, K.O. and Jaakkola, U.M. (1986) "Yersinia associated arthritis in the rat: experimental model for human reactive arthritis?", Acta PathoL MicrobioL Immunol. Scand. 94, 261–269.
   Google Scholar
• Hill, J.L. and Yu, D.T.Y. (1987) "Development of an experimental animal model for reactive arthritis induced by Yersinia enteroco-litica infection", Infect. Immun. 55, 721–726.
   PubMed Web of Science ®Google Scholar
• Toyos, J., de LOS, R., Vazquez, J., Sampedro, A. and Hardisson, C. (1990) "Yersinia enterocolitica serotype 0:3 is arthritogenic for mice", Microb. Pathog. 8, 363–370.
   PubMed Web of Science ®Google Scholar
• Toyos, J., de LOS, R., Menendez, P.J., Sampedro, A. and Hardisson, C. (1992) "Yersinia enterocolitica serotype 0:3-induced arthritis for mice. Microbiological and histopathological information", APMIS 100,455–464.
   PubMed Web of Science ®Google Scholar
• Gripenberg-Lerche, C. and Toivanen, P. (1993) "Yersinia associated arthritis in SHR rats: effect of the microbial status of the host", Ann. Rheum. Dis. 52, 223–228.
   PubMed Web of Science ®Google Scholar
• Hermann-Marker, E. and Höhler, T. (1998) "Pathogenesis of human leukocytes antigen B27- positive arthritis", Rheum. Dis. Clin. North Am. 24, 865–881.
   PubMed Web of Science ®Google Scholar
• Ym, Z., Braun, J., Neure, L., Wu, P., Liu, L., Eggens, U. and Sieper, J. (1997) "Crucial role of interleukin-10/interleukin-12 balance in the regulation of the type 2 T helper cytokine response in reactive arthritis", Arthritis Rheum. 40, 1788–1797.
   PubMedGoogle Scholar
• Mossman, T.R. and Coffman, R.L. (1989) "Th 1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties", Ann. Rev. Immunol. 7, 145–173.
   PubMed Web of Science ®Google Scholar
• Granfors, K., Jalkanen, S., von Essen, R., Lahesmaa-Rantala, R., Isomaki, 0., Pekkola:Heino, K., Merilahti-Palo, R., Saario, R., Isomaki, H. and Toivanen, A. (1989) "Yersinia antigens in synovial-fluid cells from patients with reactive arthritis", N. Engl. J. Med. 320, 216–221.
   Google Scholar
• Wuorela, M. and Granfors, K. (1998) "Infectious agents as triggers of reactive arthritis", Am. J. Med. Sci. 316, 264–270.
   PubMed Web of Science ®Google Scholar