Cytokines in Thyroid Autoimmunity

References

• Prete, D. (1998) "The concept of type 1 and type 2 helper T cells and their cytokines in humans", Int. Rev. Immunol. 16, 427–455.
   PubMedGoogle Scholar
• Prud'honune, G.J. and Piccirillo, C.A. (2000) "The inhibitory effects of transforming growth factor-beta-1 in autoimmune diseases", J. Autoimmun. 14, 23–42.
   PubMedGoogle Scholar
• Ajjan, R.A., Watson, P.F. and Weetman, A.P. (1996) "Cytokines and thyroid function", Adv. NeuroimmunoL 6, 359–386.
   PubMedGoogle Scholar
• Azmi, N., Ajjan, R.A., Findlay, C., Watson, P.F. and Weetman, AR (1997) "The detection of IL-14, IL-16 and IL-17 mRNA in the thyroid of patients with autoinunune thyroid disease", J. Endocrinol. 155(Suppl.), P74.
   Google Scholar
• Ashhab, Y., Dominguez, O., Sospedra, M., Roura-Mir, C., Lucas-Martin, A. and Pujol-Borrell, R. (1999) "A one-tube polymerase chain reaction protocol demonstrates CC chemokine overexpres-sion in Graves' disease glands", J. Clin. Endocrinol. Metab. 84, 2873–2882.
   PubMedGoogle Scholar
• Takiyama, Y, Miyokawa, N., Tokusashi, Y, et al. (2002) "Thyroid-stimulating hormone induces interleukin-18 gene expression in FRTL-5 cells: Immunohistochemical detection of interleukin-18 in autoimmune thyroid disease", Thyroid 12, 935–943.
   PubMedGoogle Scholar
• Heuer, M., Aust, G., Ode-Hakim, S. and Scherbaum, W.A. (1996) "Different cytokine mRNA profile in Graves' disease, Hashimoto's thyroiditis, and non autoimmune thyroid disorders determined by quantitative reverse transcriptase polymerase chain reaction (RT-PCR)", Thyroid 6, 97–105.
   PubMed Web of Science ®Google Scholar
• De la Vega, J.R., Vilaplana, J.C., Biro, A., Hammond, L., Bottazzo, G.F. and Mirakian, R. (1998) "IL-10 expression in thyroid glands: protective or harmful role against thyroid autoimmunity?", ClM. Exp. Immunol. 113, 126–135.
   PubMed Web of Science ®Google Scholar
• Ajjan, R.A. and Weetman, A.P. (2000) In: Rapoport, B. and McLachlan, S., eds, Graves' disease: pathgenesis and treatment (Kulwer Academic Publishers, Norwell, Massachusets, USA), pp 79–93.
   Google Scholar
• Hiromatsu, Y, Yang, D., Bednarczuk, T., Miyake, I., No, K. and Inoue, Y. (2000) "Cytokine profile in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy", J. Clin. Endocrinol. Metab. 85, 1194–1199.
   PubMed Web of Science ®Google Scholar
• Wakelkamp, I.M., Bakker, O., Baldeschi, L., Wiersinga, W.M. and Prummel, M.F. (2003) "TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients", Clin. Endocrinol. 58, 280–287.
   PubMed Web of Science ®Google Scholar
• Roura-Mir, C., Catalfamo, M., Sospedra, M., Alcalde, L., Pujol-Borrell, R. and Jaraquemada, D. (1997) "Single-cell analysis of intrathyroidal lymphocytes shows differential cytokine expression in Hashimoto's and Graves' disease", Eur. J. Immunol. 27, 3290–3302.
   PubMed Web of Science ®Google Scholar
• Okumura, M., Hidaka, Y, Matsuzuka, F., et al. (1999) "CD30 expression and interleuldn-4 and interferon--y production of intrathyroidal lymphocytes in Graves' disease", Thyroid 9, 333–339.
   PubMed Web of Science ®Google Scholar
• Lopez-Garcia, MA., Sancho, D., Sanchez-Madrid, F. and Marazuela, M. (2001) "Thyrocytes from autoimmune thyroid disorders produce the chemokines 1P-10 and Mig and attract CXCR3+ lymphocytes", J. Clin. Endocrinol. Metab. 86, 5008–5016.
   PubMedGoogle Scholar
• Aniszewski, J.P., Valyasevi, R.W. and Bahn, R.S. (2000) "Relationship between disease duration and predominant orbital T cell subset in Graves' ophthalmopathy", J. Clin. Endocrinol. Metab. 85, 776–780.
   PubMed Web of Science ®Google Scholar
• Yang, D., Hiromatsu, Y, Hoshino, T., Inoue, Y., Itoh, K. and Nonaka, K. (1999) "Dominant infiltration of T(H)l-type CD4+ T cells at the retrobulbar space of patients with thyroid-associated ophthalmopathy", Thyroid 9, 305–310.
   PubMed Web of Science ®Google Scholar
• Koumas, L, Smith, T.J. and Phipps, R.P. (2002) "Fibroblast subsets in the human orbit: Thy-1+ and Thy-1— subpopulations exhibit distinct phenotypes", Eur. J. Immunol. 32, 477–485.
   PubMed Web of Science ®Google Scholar
• Pritchard, J., Horst, N., Cruikshank, W. and Smith, T.J. (2002) "Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts", J. Immunol. 168, 942–950.
   PubMed Web of Science ®Google Scholar
• Miihlberg, T., Joba, W., Spitzweg, C., Schworm, H-D., Heberling, H-J. and Heufelder, A.E. (2000) "Interleukin-1 receptor antogonist RNA and protein expression by cultured Graves' and normal orbital fibroblasts is differentially modulated by dexamethasone and irradiation", J. ClM. Endocrinol. Metab. 85, 734–742.
   PubMedGoogle Scholar
• Metcalfe, R.A., McIntosh, R.S., Marelli-Berg, F., Lombardi, G., Lechler, R. and Weetman, A.P. (1998) "Detection of CD40 on human thyroid follicular cells: analysis of expression and function", J. Clin. Endocrinol. Metab. 83, 1268–1274.
   PubMed Web of Science ®Google Scholar
• Paolieri, F., Salmaso, C., Battifora, M., et al. (1999) "Possible pathogenic relevance of interleukin-1 beta in destructive organ-specific autoimmune disease (Hashimoto's thyroiditis)", Ann. NY Acad. Sci. 876, 221–228.
   PubMed Web of Science ®Google Scholar
• Weetman, A.P. (2003) "Autoimmune thyroid disease: propagation and progression", Eur. J. Endocrinol. 148, 1–9.
   PubMed Web of Science ®Google Scholar
• Palazzo, F.F., Hammond, L.J., Goode, A.W. and Mirakian, R. (2000) "Death of the autoimmune thyrocyte: is it pushed or does it jump?", Thyroid 10, 561–572.
   PubMedGoogle Scholar
• Heufelder, A.E. (2000) "Pathogenesis of ophthalmopathy in autoimmune thyroid disease", Rev. Endocrinol. Metab. Disord. 1, 87–95.
   PubMedGoogle Scholar
• Jyonouchi, S.C., Valyasevi, R.W., Harteneck, D.A., Dutton, C.M. and Bahn, R.S. (2001) "Interleukin-6 stimulates thyrotropin receptor expression in human orbital preadipocyte fibroblasts from patients with Graves' ophthalmopathy", Thyroid 11, 929–934.
   PubMed Web of Science ®Google Scholar
• Bahn, R.S. (2002) "Thyrotropin receptor expression in orbital adipose/connective tissues from patients with thyroid-associated ophthalmopathy", Thyroid 12, 193–195.
   PubMed Web of Science ®Google Scholar
• Valyasevi, R.W., Jyonouchi, S.C., Dutton, CM., Munsakul, N. and Bahn, R.S. (2001) "Effect of tumor necrosis factor-alpha, interferon-gamma, and transforming growth factor-beta on adipogenesis and expression of thyrotropin receptor in human orbital preadipocyte fibroblasts", J. ClM. EndocrinoL Metab. 86, 501–503.
   PubMedGoogle Scholar
• Molnar, I. and Balazs, C. (1997) "High circulating IL-6 level in Graves' ophthalmopathy", Autoimmunity 25, 91–96.
   PubMed Web of Science ®Google Scholar
• Nishikawa, T., Yamashita, S., Namba, H., et au. (1993) "interferon--y inhibition of human thyrotropin receptor gene expression", J. Clin. EndocrinoL Metal,. 77, 1084–1089.
   PubMedGoogle Scholar
• Ajjan, R.A., Kammarudin, N.A., Crisp, M., Watson, P.F., Ludgate, M. and Weetman, A.P. (1998) "Regulation and tissue distribution of the human sodium iodide symporter gene", ClM. EndocrinoL 49, 517–523.
   PubMedGoogle Scholar
• Schumm-Draeger, P.M. (2001) "Sodium/iodide symporter (NIS) and cytokines", Exp. ClM. EndocrinoL Diabetes 109, 32–34.
   PubMedGoogle Scholar
• Rasmussen, AK., Kayser, L., Rasmussen, U.F. and Bendtzen, K. (1994) "Influence of tumour necrosis factor-I3 and interferon-y, separately and added together with interleukin-113, on the function of cultured human thyroid cells", J. Endocrinol. 143, 359–365.
   PubMedGoogle Scholar
• Wang, L., Teng, W. and Shan, Z. (2000) "Effect of IFN-gamma, IL-4 on proliferation and synthesis of hyaluronic acid and collagen in cultured human retroorbital fibroblasts in vitro", Chin. Med. J. 113, 907–910.
   PubMedGoogle Scholar
• Koh, L.K.H., Greenspan, F.S. and Yeo, P.P.B. (1998) "Interferon-« induced thyroid dysfunction: three clinical presentations and a review of the literature", Thyroid 8, 891–896.
   Google Scholar
• Carella, C., Mazziotti, G., Morisco, F., et al. (2001) "Long-term outcome of interferon-alpha-induced thyroid autoimmunity and prognostic influence of thyroid autoantibody pattern at the end of treatment", J. Clin. Endocrinol. Metab. 86, 1925–1929.
   PubMed Web of Science ®Google Scholar
• Monzani, F., Caraccio, N., Meucci, G., et al. (1999) "Effect of 1-year treatment with interferon-13lb on thyroid function and autoimmunity in patients with multiple sclerosis", Eur. J. EndocrinoL 141, 325–331.
   PubMed Web of Science ®Google Scholar
• Durelli, L., Ferrero, B., Ogerro, A., et al. (2001) "Liver and thyroid function and autoimmunity during interferon-beta lb treatment for multiple sclerosis", Neurology 57, 1363–1370.
   PubMed Web of Science ®Google Scholar
• De Metz, J., Romijn, J.I., Ended, E., Crossmit, E.P. and Sauerwein, H.P. (2000) "Administration of interferon-gamma in healthy subjects does not modulate thyroid hormone metabolism", Thyroid 10, 87–91.
   PubMedGoogle Scholar
• Torpy, D.J., Tsigos, C., Lotsikas, A.J., et al. (1998) "Acute and delayed effects of a single dose injection of IL-6 on thyroid function in healthy humans", Metabolism 47, 1289–1293.
   PubMedGoogle Scholar
• Binaghi, M., Levy, C., Douvin, C., Guittard, M., Soubrane, G. and Coscas, G. (2002) "Severe thyroid ophthalmopathy related to interferon alpha therapy", J. Fr. Ophthalmol. 25, 412–415.
   PubMedGoogle Scholar
• Imagawa, A., Itoh, N., Hanafusa, T., et al. (1995) "Autoimmune endocrine disease induced by recombinant IFN-« therapy for chronic active type C hepatitis", J. ClM. EndocrinoL Metab. 80, 922–926.
   PubMedGoogle Scholar
• Hidaka, Y, Okumura, M., Shimaoka, Y, Takeoka, K., Tada, H. and Amino, N. (1998) "Increased serum concentration of interleukin-5 in patients with Graves' disease and Hashimoto's thyroiditis", Thyroid 8, 235–239.
   PubMed Web of Science ®Google Scholar
• Al-Humaidi, MA. (2000) "Serum cytokine levels in Graves' disease", Saudi Med. J. 7, 639–644.
   Google Scholar
• Bossowski, A. and Urban, M. (2001) "Serum levels of cytokines in children and adolescents with Graves' disease and non-toxic goiter", J. Pediatr. Endocrinol. Metab. 14, 741–747.
   PubMedGoogle Scholar
• Taman', M., Matsuura, B. and Onji, M. (1999) "Increased levels of interleukin-12 in Graves' disease", Eur. J. Endocrinol. 141, 111–116.
   PubMedGoogle Scholar
• Miyauchi, S., Matsuura, B. and Onji, M. (2000) "Increased levels of serum interleukin-18 in Graves' disease", Thyroid 10, 815–819.
   PubMed Web of Science ®Google Scholar
• Komiya, I., Amada, T., Sato, A., Kould, T., Nishimori, T. and Takasu, N. (2001) "Remission and recurrence of hyperthyroid Graves' disease during and after methimazole treatment when assessed by IgE and interleukin 13", J. Clin. Endocrinol. Metab. 86, 3540–3544.
   PubMedGoogle Scholar
• Maziotti, G., Sorvillo, F., Naclerio, C., et al. (2003) "Type-1 response in peripheral CD4+ and CD8+ T cells from patients with Hashimoto's thyroiditis", Eur. J. Endocrinol. 148, 383–388.
   PubMedGoogle Scholar
• Salvi, M., Pedrazzoni, M., Girasole, G., et al. (2000) "Serum concentrations of proinflammatory cytokines in Graves' disease: effect of treatment, thyroid function, ophthalmopathy and cigarette smoking", Eur. J. Immunol. 143, 197–202.
   Google Scholar
• Mysliwiec, J., Kretowski, A., Topolska, J., et al. (2001) "Serum Thl and Th2 profile cytokine level changes in patients with Graves' ophthalmopathy treated with corticosteroids", Honn. Metab. Res. 33, 739–743.
   PubMed Web of Science ®Google Scholar
• Wakelkamp, LM., Gerding, M.N., Van Der Meer, J.W., Prununel, M.F. and Wiersinga, W.M. (2000) "Both Th 1- and Th2-derived cytokines in serum are elevated in Graves' ophthalmopathy", UM. Exp. Immunol. 121, 453–457.
   PubMed Web of Science ®Google Scholar
• Hofbauer, L.C., Muhlberg, T., Konig, A., Heufelder, G., Schworm, H.D. and Heufelder, A.E. (1997) "Soluble interleukin-1 receptor antagonist serum levels in smokers and nonsmokers with Graves' ophthalmopathy undergoing orbital radiotherapy", J. Clin. Endo-crinol. Metab. 82, 2244–2247.
   PubMedGoogle Scholar
• Mysliwiec, J., Kretowski, A., Stepien, A., Mironczuk, K. and Kinalska, I. (2003) "Interleukin-18 and transforming growth factor-betal in the sera of patients with Graves' ophthalmopathy treated with corticosteroids", Int. Immunophanna-col. 3, 549–552.
   PubMedGoogle Scholar