408
Views
216
CrossRef citations to date
0
Altmetric
Original Article

Microarray Analysis of Interferon-regulated Genes in SLE

, &
Pages 481-490 | Published online: 03 Aug 2009

References

  • Hooks, J.J., Moutsopoulos, H.M., Geis, SA., Stahl, NI., Decker, J.L. and Notkins, AL. (1979) "Immune interferon in the circulation of patients with autoimmune disease", N. EngL J. Med. 301, 5–8
  • Hooks, J.J., Jordan, G.W., Cupps, T., Moutsopoulos, H.M., Fauci, A.S. and Notkins, AL. (1982) "Multiple interferons in the circulation of patients with systemic lupus erythematosus and vasculitis", Arthritis Rheum. 25, 396–400
  • Shi, S.N., Feng, S.F., Wen, Y.M., He, L.F. and Huang, Y.X. (1987) "Serum interferon in systemic lupus erythematosus", Br. J. DennatoL 117, 155–159
  • Preble, O.T., Black, R.J., Friedman, R.M., Klippel, J.H. and Vilcek, J. (1982) "Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon", Science 216, 429–431
  • Yee, A.M., Yip, Y.K., Fischer, RD. and Buyon, J.P. (1990) "Serum activity that confers acid lability to alpha-interferon in systemic lupus erythematosus: its association with disease activity and its independence from circulating alpha-interferon", Arthritis Rheum. 33, 563–568
  • Boumpas, D.T., Hook, J.J., Popovic, M., Tsokos, G.C. and Mann, D.L. (1985) "Human T-cell leukemia/lymphoma virus I and/or Epstein-Barr virus-infected B-cell lines spontaneously produce acid-labile alpha-interferon", J. Clin. Immunol. 5, 340–344
  • Capobianchi, M.R., Mattana, P., Mercuri, F., Conciatori, G., Ameglio, F., Ankel, H. and Dianzani, F. (1992) "Acid lability is not an intrinsic property of interferon-alpha induced by HIV-infected cells", J. Interferon Res. 12, 431–438
  • Rich, S.A. (1981) "Human lupus inclusions and interferon", Science 213, 772–775
  • Ronnblom, L.E., Alm, G.V. and Oberg, K.E. (1990) "Possible induction of systemic lupus erythematosus by interferon-alpha treatment in a patient with a malignant carcinoid tumour", J. Intern. Med. 227, 207–210
  • Wandl, U., Nagel-Hiemke, M., May, D., Kreuzfelder, E., Kloke, O., Kranzhoff, M., Seeber, S. and Niederle, N. (1992) "Lupus-like autoimmune disease induced by interferon therapy for myelopro-liferative disorders", Clin. Immunol. Immunopathol. 65, 70–74
  • Zhang, Z.X., Milich, DR., Peterson, DL., Birkett, A., Schvarcz, R., Weiland, O. and Sallberg, M. (1997) "Interferon-alpha treatment induces delayed CD4 proliferative responses to the hepatitis C virus nonstructural protein 3 regardless of the outcome of therapy", J. Infect. Dis. 175, 1294–1301
  • Schilling, P.J., Kurzrock, R., Kantarjian, H., Gutterman, J.U. and Talpaz, M. (1991) "Development of systemic lupus erythematosus after interferon therapy for chronic myelogenous leukemia", Cancer 68, 1536–1537
  • Pittau, E., Bogliolo, A., Tinti, A., Mela, Q., Ibba, G., Salis, G. and Perpignano, G. (1997) "Development of arthritis and hypothyroid-ism during alph-interferon therapy for chronic hepatitis C", Clin. Exp. Rheumatol. 15, 415–419
  • Gota, C. and Calabrese, L. (2003) "Induction of clinical autoimmune disease by therapeutic interferon-alpha", Autoimmu-nity 36
  • Peng, S.L., Moslehi, J. and Craft, J. (1997) "Roles of interferon-gamma and interleukin-4 in murine lupus", J. CIM. Investig. 99, 1936–1946
  • Lawson, BR., Prud'homme, G.J., Chang, Y, Gardner, RA., Kuan, J., Kono, D.H. and Theofilopoulos, A.N. (2000) "Treatment of murine lupus with cDNA encoding 1FN-ganunaR/Fc", J. Clin. Investig. 106, 207–215
  • Santiago-Raber, ML., Baccala, R., Haraldsson, KM., Choubey, D., Stewart, TA., Kono, D.H. and Theofilopoulos, AN. (2003) "Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice", J. Exp. Med. 197, 777–788
  • Braun, D., Geraldes, P. and Demengeot, J. (2003) "Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice", J. Autoimmun. 20, 15–25
  • Kono, D.H., Baccala, R. and Theofilopoulos, AN. (2003) "Inhibition of lupus by genetic alteration of the interferon-a/13 receptor", Autoimmunity 36
  • Riinnblom, L., Eloranta, M.-L. and Alin, G.V. (2003) "Role of natural interferon-a producing cells (plasmacytoid dendritic cells) in autoimmunity", Autoimmunity 36
  • Vallin, H., Blomberg, S., Alm, G.V., Cederblad, B. and Ronnblom, L. (1999) "Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (1FN-a) production acting on leukocytes resembling immature dendritic cells", Clin. Exp. Immunol. 115, 196–202
  • Vallin, H., Peters, A., Alm, G.V. and Ronnblom, L. (1999) "Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous 1FN-alpha inducer in systemic lupus erythematosus", J. Immunol. 163, 6306–6313
  • Bave, U., Alm, G.V. and Ronnblom, L. (2000) "The combination of apoptotic U937 cells and lupus IgG is a potent 1FN-alpha inducer", J. Immunol. 165, 3519–3526
  • Bave, U., Vallin, H., Alm, G.V. and Ronnblom, L. (2001) "Activation of natural interferon-alpha producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines", J. Autoimmun. 17, 71–80
  • Magnusson, M., Magnusson, S., Vallin, H., Ronnblom, L. and Alin, G.V. (2001) "Importance of CpG dinucleotides in activation of natural 1FN-alpha-producing cells by a lupus-related oligodeoxy-nucleotide", Scand. J. Immunol. 54, 543–550
  • Blanco, P., Palucka, AK., Gill, M., Pascual, V. and Banchereau, J. (2001) "Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus", Science 294, 1540–1543
  • Radvanyi, L.G., Banerjee, A., Weir, M. and Messner, H. (1999) "Low levels of interferon-alpha induce CD86 (B7.2) expression and accelerates dendritic cell maturation from human peripheral blood mononuclear cells", Scand. J. Immunol. 50, 499–509
  • Luft, T., Pang, K.C., Thomas, E., Herzog, P., Hart, D.N., Trapani, J. and Cebaon, J. (1998) "Type I 1FNs enhance the terminal differentiation of dendritic cells", J. Immunol. 161, 1947–1953
  • Crow, M.K. (2003) "Interferon-alpha: a new target for therapy in SLE?", Arthritis Rheum. 48, 2396–2401
  • Crow, M.K., George, S., Paget, S.A., Ly, N., Woodward, R., Fry, K., Chan, A., Prentice, J. and Wohlgemuth, J. (2002) "Expression of an interferon-alpha gene program in SLE", Arthritis Rheum. 46, S281
  • Baechler, E.C., Batliwalla, FM., Karypis, G., Gaffney, P.M., Ortmann, WA., Espe, K.J., Shark, KB., Grande, W.J., Hughes, KM., Kapur, V, Gregersen, P.K. and Behrens, T.W. (2003) "Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus", Proc. Natl Acad. Sci. USA 100, 2610–2615
  • Bennett, L., Palucka, AK., Arce, E., Cantrell, V., Borvak, J., Banchereau, J. and Pascual, V. (2003) "Interferon and granulopoi-esis signatures in systemic lupus erythematosus blood", J. Exp. Med. 197, 711–723
  • Han, G.M., Chen, S.L., Shen, N., Ye, S., Bao, C.D. and Gu, Y.Y. (2003) "Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray", Genes. Immun. 4, 177–186
  • Brown, P.O. and Botstein, D. (1999) "Exploring the new world of the genome with DNA microarrays", Nat. Genet. 21, 33–37
  • Alizadeh, A.A., Eisen, MB., Davis, R.E., Ma, C., Lossos, IS., Rosenwald, A., Boldrick, J.C., Sabet, H., Tran, T., Yu, X., Powell, J.I., Yang, L., Marti, G.E., Moore, T., Hudson, Jr, J., Lu, L., Lewis, D.B., Tibshirani, R., Sherlock, G., Chan, W.C., Greiner, T.C., Weisenberger, D.D., Armitage, J.0., Warnke, R. and Staudt, L.M. (2000) "Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling", Nature 403, 503–511
  • Crow, M.K. and Wohlgemuth, J. (2003) "Microarray analysis of gene expression in lupus", Arthritis Res. Ther 5, 279–287
  • Biron, C.A. (2001) "Interferons alpha and beta as immune regulators—a new look", Immunity 14, 661–664
  • Der, S.D., Zhou, A., Williams, B.R. and Silverman, R.H. (1998) "Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays", Proc. Natl Acad. Sci. USA 95, 15623–15628
  • Barnes, B.J., Moore, P.A. and Pitha, P.M. (2001) "Virus-specific activation of a novel interferon regulatory factor 5, results in the induction of distinct interferon alpha genes", J. Biol. Chem. 276, 23382–23390
  • Su, Al., Pezacki,Wodicka, L., Brideau, A.D., Supekova, L.,Thimme, R., Wieland, S., Bukh, J., Purcell, R.H., Schultz, P.G. and Chisari, F.V. (2002) "Genomic analysis of the host response to hepatitis C virus infection", Proc. Natl Acad. Sci. USA 99, 15669–15674
  • Bridge, A.J., Pebernard, S., Ducraux, A., Nicoulaz, A.-L. and Iggo, R. (2003) "Induction of an interferon response by RNAi vectors in mammalian cells", Nat. Genet. 34, 263–264
  • Tusher, V.G., Tibshirani, R. and Chu, G. (2001) "Significance analysis of microanays applied to the ionizing radiation response", Proc. Natl Acad. Sci. USA 98, 5116–5121
  • Rus, V, Atamas, S.P., Shustova, V, Luzina, LG., Selaru, F., Magder, L.S. and Via, C.S. (2002) "Expression of cytokine- and chemokine-related genes in peripheral blood mononuclear cells from lupus patients by cDNA array", Clin. Immunol. 102, 283–290
  • Maas, K., Chan, S., Parker, J., Slater, A., Moore, J., Olsen, N. and Aune, T.M. (2002) "Cutting edge: molecular portrait of human autoimmune disease", J. Immunol. 169, 5–9
  • Tezak, Z., Hoffman, E.P., Lutz, J.L., Fedczyna, TO., Stephan, D., Bremer, E.G., Krasnoselska-Riz, I., Kumar, A. and Pachman, L.M. (2002) "Gene expression profiling in DQA1*0501* ± children with untreated dermatomyositis: a novel model of pathogenesis", J. Immunol. 168, 4154–4163
  • Wandinger, K.-P., Sturzebecher, C.-S., Bielekova, B., Detore, G., Rosenwald, A., Staudt, L.M., McFarland, H.F. and Martin, R. (2001) "Complex immunomodulatory effects of interferon-I3 in multiple sclerosis include the upregulation of T helper 1-associated marker genes", Ann. Neurol. 50, 349–357
  • Carmody, R.J., Hilliard, B., Maguschak, K., Chodosh, L.A. and Chen, Y.H. (2002) "Genomic scale profiling of autoimmune inflammation in the central nervous system: the nervous response to inflammation", J. Neuroimmunol. 133, 95–107
  • Mycko, M.P., Papoian, R., Boschert, U., Raine, C.S. and Selmaj, K.W. (2003) "cDNA microanay analysis in multiple sclerosis lesions: detection of genes associated with disease activity", Brain 126, 1048–1057
  • Whitney, A.R., Diehn, M., Popper, S.J., Alizadeh, A.A., Boldrick, J.C., Reiman, D.A. and Brown, P.O. (2003) "Individuality and variation in gene expression patterns in human blood", Proc. Natl Acad. Sci. USA 100, 1896–1901
  • Svensson, H., Johannisson, A., Nikkila, T., Alin, G.V. and Cederblad, B. (1996) "The cell surface phenotype of human natural interferon-a producing cells as determined by flow cytometry", Scand. J. Immunol. 44, 164–172
  • Siegal, F.P., Kadowald, N., Shodell, M., Fitzgerald-Bocarsly, PA., Shah, K., Ho, S., Antonenko, S. and Liu, Y.J. (1999) "The nature of the principal type I interferon-producing cells in human blood", Science 284, 1835–1837
  • Ronnblom, L. and Alm, G.V. (2001) "A pivotal role for the natural interferon a-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus", J. Exp. Med. 194, 59–63
  • Brinlunann, V., Geiger, T., Alkan, S. and Heusser, C.H. (1993) "Interferon alpha increases the frequency of interferon gamma-producing human CD4 T cells", J. Exp. Med. 178, 1655–1663
  • Aman, M.J., Tretter, T., Eisenbeis, I., Bug, G., Decker, T., Aulitzky, W.E., Tilg, H., Huber, C. and Peschel, C. (1996) "Interferon-alpha stimulates production of interleukin-10 in activated CD4+ T cells and monocytes", Blood 87, 4731–4736
  • Le Bon, A., Schiavoni, G., D'Agostino, G., Gresser, I., Belardelli, F. and Tough, D.F. (2001) "Type I interferons potently enhance immunity and can promote isotype switching by stimulating dendritic cells in vivo", Immunity 14, 461–470

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.