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Original

IgA class antibodies to 2-oxo-acid dehydrogenase complex are not predictive markers of histopathological progression in primary biliary cirrhosis

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Pages 107-112 | Received 27 Sep 2005, Accepted 13 Feb 2006, Published online: 07 Jul 2009

References

  • Kaplan MM. Primary biliary cirrhosis. N Engl J Med 1996; 335: 1570–1580
  • Mackay IR, Gershwin ME. Pathogenesis of primary biliary cirrhosis. Autoimmune liver diseases2nd ed., EL Krawitt, RH Wiesner, M Nishioka. Elsevier, Amsterdam 1998; 49–69
  • Nishio A, Van de Water J, Leung PSC, Joplin R, Neuberger JM, Lake J, Bjorkland A, Totterman TH, Peters M, Worman HJ, Ansari AA, Coppel RL, Gershwin ME. Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis. Hepatology 1997; 25: 1085–1089
  • Floreani A, Baragiotta A, Pizzuti D, Martines D, Cecchetto A, Chiarelli S. Mucosal IgA defect in primary biliary cirrhosis. Am J Gastroenterol 2002; 97: 508–510
  • Masuda J, Omagari K, Ohba K, Hazama H, Kadokawa Y, Kinoshita H, Hayashida K, Hayashida K, Ishibashi H, Nakanuma Y, Kohno S. Correlation between histopathological findings of the liver and IgA class antibodies to 2-oxo-acid dehydrogenase complex in primary biliary cirrhosis. Dig Dis Sci 2003; 48: 932–938
  • Kadokawa Y, Omagari K, Hazama H, Ohba K, Masuda J, Kinoshita H, Hayashida K, Isomoto H, Mizuta Y, Murase K, Murata I, Kohno S. Evaluation of newly developed ELISA using “MESACUP-2 Test Mitochondrial M2” kit for the diagnosis of primary biliary cirrhosis. Clin Biochem 2003; 36: 203–210
  • Stanley CJ, Perham RN. Purification of 2-oxo acid dehydrogenase multienzyme complexes from ox heart by a new method. Biochem J 1980; 191: 147–154
  • Kinoshita H, Omagari K, Matsuo I, Yamaguchi K, Ikuno N, Kohno S. Frequency of IgG, IgM, and IgA class autoantibodies against 2-oxo-acid dehydrogenase complex in 102 Japanese patients with primary biliary cirrhosis. Hepatol Res 1999; 15: 163–171
  • Scheuer PJ, Lefkowitch JH. Liver biopsy interpretation6th ed. W.B. Saunders, London 2000; 66–91
  • Karr MA. The structure and function of human IgA. Biochem J 1990; 271: 285–296
  • Turner M, Owen M. Antigen receptor molecules. Immunology3rd ed., I Roitt, J Brostoff, D Male. Mosby, London 1993; 4.1–4.20
  • Olas K, Butterweck H, Teschner W, Schwarz HP, Reipert BM. Immunomodulatory properties of human serum immunoglobulin A: Anti-inflammatory and pro-inflammatory activities in human monocytes and peripheral blood mononuclear cells. Clin Exp Immunol 2005; 140: 478–490
  • Tanaka A, Nalbandian G, Leung PSC, Benson GD, Munoz S, Findor JA, Branch AD, Coppel RL, Ansari AA, Gershwin ME. Mucosal immunity and primary biliary cirrhosis: Presence of antimitochondrial antibodies in urine. Hepatology 2000; 32: 910–915
  • Matsumura S, Van de Water J, Leung P, Odin JA, Yamamoto K, Gores GJ, Mostov K, Ansari AA, Coppel RL, Shiratori Y, Gershwin ME. Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. Hepatology 2004; 39: 1415–1422
  • Fukushima N, Nalbandian G, Van de Water J, White K, Ansari AA, Leung P, Kenny T, Kamita SG, Hammock BD, Coppel RL, Stevenson F, Ishibashi H, Gershwin ME. Characterization of recombinant monoclonal IgA anti-PDC-E2 autoantibodies derived from patients with primary biliary cirrhosis. Hepatology 2002; 36: 1383–1392
  • Kisand KE, Kisand KV, Karvonen A-L, Vuoristo M, Mattila J, Makinen J, Uibo R. Antibodies to pyruvate dehydrogenase in primary biliary cirrhosis: Correlation with histology. APMIS 1998; 106: 884–892
  • Nakajima M, Shimizu H, Miyazaki A, Watanabe S, Kitami N, Sato N. Detection of IgA, IgM, and IgG subclasses of anti-M2 antibody by immunoblotting in autoimmune cholangitis: Is autoimmune cholangitis an early stage of primary biliary cirrhosis?. J Gastroenterol 1999; 34: 607–612

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