Advanced search
Publication Cover
Autoimmunity Volume 40, 2007 - Issue 4
Submit an article Journal homepage
189
Views
24
CrossRef citations to date
0
Altmetric
Original

Purified apoptotic bodies stimulate plasmacytoid dendritic cells to produce IFN-alpha

BRIEF DEFINITE REPORT

P. Heyder Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
I. Bekeredjian-Ding Department of Medical Microbiology and Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
,
M. Parcina Department of Medical Microbiology and Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
,
N. Blank Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
A. D. Ho Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
M. Herrmann Department of Internal Medicine 3, Institute of Clinical Immunology and Rheumatology, University Hospital Erlangen, 91054, Erlangen, Germany
,
Hanns-Martin Lorenz Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
K. Heeg Department of Medical Microbiology and Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
&
M. Schiller Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
 show all
Pages 331-332 | Published online: 07 Jul 2009

References

  • Liu G, et al. Phagocytosis of apoptotic cells and immune regulation. Scand J Immunol 2006; 64(1)1–9
  • Gaipl US, et al. Clearance of apoptotic cells in human SLE. Curr Dir Autoimmun 2006; 9: 173–187
  • White S, Rosen A. Apoptosis in systemic lupus erythematosus. Curr Opin Rheumatol 2003; 15(5)557–562
  • Lorenz HM, et al. Hyporesponsiveness to gammac-chain cytokines in activated lymphocytes from patients with systemic lupus erythematosus leads to accelerated apoptosis. Eur J Immunol 2002; 32(5)1253–1263
  • Kirou KA, et al. Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus. Arthritis Rheum 2004; 50(12)3958–3967
  • Baechler EC, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci USA 2003; 100(5)2610–2615
  • Lovgren T, et al. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 2004; 50(6)1861–1872
  • Savarese E, et al. U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 2006; 107(8)3229–3234
  • Means TK, et al. Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J Clin Invest 2005; 115(2)407–417
  • Jego G, et al. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 2003; 19(2)225–234
  • Cella M, et al. Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization. Nat Immunol 2000; 1(4)305–310

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.