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Original

Gene–environment interactions in the aetiology of systemic lupus erythematosus

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Pages 613-617 | Received 10 Mar 2007, Accepted 15 Apr 2007, Published online: 07 Jul 2009

References

  • Fries JF, Holman HR. Systemic lupus erythematosus: A clinical analysis. Major Probl Intern Med 1975; 6: v-199
  • Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25(11)1271–1277
  • Pascual V, Banchereau J, Palucka AK. The central role of dendritic cells and interferon-alpha in SLE. Curr Opin Rheumatol 2003; 15(5)548–556
  • Wandstrat A, Wakeland E. The genetics of complex autoimmune diseases: Non-MHC susceptibility genes. Nat Immunol 2001; 2(9)802–809
  • Manderson AP, Botto M, Walport MJ. The role of complement in the development of systemic lupus erythematosus. Annu Rev Immunol 2004; 22: 431–456
  • Edwards CJ, Cooper C. Early environmental exposure and the development of lupus. Lupus 2006; 15(11)814–819
  • Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349(16)1526–1533
  • Edwards CJ, Syddall H, Goswami R, Goswami P, Dennison EM, Cooper C. Infections in infancy and the presence of antinuclear antibodies in adult life. Lupus 2006; 15(4)213–217
  • Phillips DI. External influences on the fetus and their long-term consequences. Lupus 2006; 15(11)794–800
  • Klareskog L, Stolt P, Lundberg K, Kallberg H, Bengtsson C, Grunewald J, et al. A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum 2006; 54(1)38–46
  • Tsao BP. The genetics of human systemic lupus erythematosus. Trends Immunol 2003; 24(11)595–602
  • Deapen D, Escalante A, Weinrib L, Horwitz D, Bachman B, Roy-Burman P, et al. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 1992; 35(3)311–318
  • Truedsson L, Sturfelt G, Johansen P, Nived O, Thuresson B. Sharing of MHC haplotypes among patients with systemic lupus erythematosus from unrelated Caucasian multicase families: Disease association with the extended haplotype [HLA-B8,SC01, DR17]. J Rheumatol 1995; 22(10)1852–1861
  • Nimmerjahn F, Ravetch JV. Fcgamma receptors: Old friends and new family members. Immunity 2006; 24(1)19–28
  • Davies KA, Peters AM, Beynon HL, Walport MJ. Immune complex processing in patients with systemic lupus erythematosus. In vivo imaging and clearance studies. J Clin Invest 1992; 90(5)2075–2083
  • Russell AI, Cunninghame Graham DS, Shepherd C, Roberton CA, Whittaker J, Meeks J, et al. Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus. Hum Mol Genet 2004; 13(1)137–147
  • Garred P, Voss A, Madsen HO, Junker P. Association of mannose-binding lectin gene variation with disease severity and infections in a population-based cohort of systemic lupus erythematosus patients. Genes Immun 2001; 2(8)442–450
  • Prokunina L, Castillejo-Lopez C, Oberg F, Gunnarsson I, Berg L, Magnusson V, et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 2002; 32(4)666–669
  • Witkin SS, Gerber S, Ledger WJ. Influence of interleukin-1 receptor antagonist gene polymorphism on disease. Clin Infect Dis 2002; 34(2)204–209
  • Tucci M, Barnes EV, Sobel ES, Croker BP, Segal MS, Reeves WH, et al. Strong association of a functional polymorphism in the monocyte chemoattractant protein 1 promoter gene with lupus nephritis. Arthritis Rheum 2004; 50(6)1842–1849
  • Sigurdsson S, Nordmark G, Goring HH, Lindroos K, Wiman AC, Sturfelt G, et al. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 2005; 76(3)528–537
  • Clynes R, Dumitru C, Ravetch JV. Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 1998; 279(5353)1052–1054
  • Matsumoto K, Watanabe N, Akikusa B, Kurasawa K, Matsumura R, Saito Y, et al. Fc receptor-independent development of autoimmune glomerulonephritis in lupus-prone MRL/lpr mice. Arthritis Rheum 2003; 48(2)486–494
  • Nguyen C, Limaye N, Wakeland EK. Susceptibility genes in the pathogenesis of murine lupus. Arthritis Res 2002; 4(3)S255–S263
  • Sarzi-Puttini P, Atzeni F, Iaccarino L, Doria A. Environment and systemic lupus erythematosus: An overview. Autoimmunity 2005; 38(7)465–472
  • Bengtsson AA, Rylander L, Hagmar L, Nived O, Sturfelt G. Risk factors for developing systemic lupus erythematosus: A case-control study in southern Sweden. Rheumatology (Oxford) 2002; 41(5)563–571
  • McClain MT, Heinlen LD, Dennis GJ, Roebuck J, Harley JB, James JA. Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. Nat Med 2005; 11(1)85–89
  • Van GM, Moens U, Bendiksen S, Rekvig OP. Autoimmunity to nucleosomes related to viral infection: A focus on hapten–carrier complex formation. J Autoimmun 2003; 20(2)171–182
  • Harley JB, Harley IT, Guthridge JM, James JA. The curiously suspicious: A role for Epstein–Barr virus in lupus. Lupus 2006; 15(11)768–777
  • Sarzi-Puttini P, Atzeni F, Capsoni F, Lubrano E, Doria A. Drug-induced lupus erythematosus. Autoimmunity 2005; 38(7)507–518
  • Perry HM, Jr., Tan EM, Carmody S, Sakamoto A. Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine. J Lab Clin Med 1970; 76(1)114–125
  • Costenbader KH, Karlson EW. Cigarette smoking and systemic lupus erythematosus: A smoking gun?. Autoimmunity 2005; 38(7)541–547
  • Rubin RL, Hermanson TM, Bedrick EJ, McDonald JD, Burchiel SW, Reed MD, et al. Effect of cigarette smoke on autoimmunity in murine and human systemic lupus erythematosus. Toxicol Sci 2005; 87(1)86–96
  • Lockshin MD. Sex differences in autoimmune disease. Lupus 2006; 15(11)753–756
  • Bijl M, Kallenberg CG. Ultraviolet light and cutaneous lupus. Lupus 2006; 15(11)724–727
  • Hess EV. Environmental chemicals and autoimmune disease: Cause and effect. Toxicol 2002; 181/182: 65–70
  • Fraser PA, Ding WZ, Mohseni M, Treadwell EL, Dooley MA, St CE, et al. Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: A possible gene–environment interaction for autoimmunity. J Rheumatol 2003; 30(2)276–282
  • Suwannaroj S, Lagoo A, Keisler D, McMurray RW. Antioxidants suppress mortality in the female NZB × NZW F1 mouse model of systemic lupus erythematosus (SLE). Lupus 2001; 10(4)258–265
  • Karlson EW, Watts J, Signorovitch J, Bonetti M, Wright E, Cooper GS, et al. Effect of glutathione S-TRANSFERASE polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: Results from the roxbury lupus project. Arthritis Rheum 2007; 56(1)244–254
  • Cooper GS, Treadwell EL, Dooley MA, St Clair EW, Gilkeson GS, Taylor JA. N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus. J Rheumatol 2004; 31(1)76–80
  • Reidenberg MM, Drayer DE, Lorenzo B, Strom BL, West SL, Snyder ES, et al. Acetylation phenotypes and environmental chemical exposure of people with idiopathic systemic lupus erythematosus. Arthritis Rheum 1993; 36(7)971–973
  • Foppa I, Spiegelman D. Power and sample size calculations for case-control studies of gene–environment interactions with a polytomous exposure variable. Am J Epidemiol 1997; 146(7)596–604
  • Khoury MJ, Flanders WD. Nontraditional epidemiologic approaches in the analysis of gene–environment interaction: Case-control studies with no controls!. Am J Epidemiol 1996; 144(3)207–213
  • Ohlsson R, Gondor A. Epigenetics-cellular memories-affect disease development. Lakartidningen 2006; 103(12)919–925
  • Ballestar E, Esteller M, Richardson BC. The epigenetic face of systemic lupus erythematosus. J Immunol 2006; 176(12)7143–7147
  • Januchowski R, Prokop J, Jagodzinski PP. Role of epigenetic DNA alterations in the pathogenesis of systemic lupus erythematosus. J Appl Genet 2004; 45(2)237–248

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