Predictors of autoimmune disease: Autoantibodies and beyond

References

• Krischer J. The biostatistics of prediction. Autoimmunity 2004; 37: 261–263
   PubMed Web of Science ®Google Scholar
• O'Leary PC, Feddema PH, Michelangeli VP, Leedman PJ, Chew GT, Knuiman M, et al. Investigations of thyroid hormones and antibodies based on a community health survey: The Busselton thyroid study. Clin Endocrinol (Oxf) 2006; 64: 97–104
   PubMed Web of Science ®Google Scholar
• Vanderpump MP, Tunbridge WM, French JM, Appleton D, Bates D, Clark F, et al. The incidence of thyroid disorders in the community: A twenty-year follow-up of the Whickham survey. Clin Endocrinol (Oxf) 1995; 43: 55–68
   PubMed Web of Science ®Google Scholar
• Rose NR. Moving from prediction to prevention. The Scientist 2007; Supplement: 68–76
   Google Scholar
• Rose NR. Prediction and prevention of autoimmune disease: A personal perspective. Ann N Y Acad Sci 2007; 1109: 117–128
   PubMed Web of Science ®Google Scholar
• Rose NR. Predictive autoantibodies: Past, present and future. From etiopathogenesis to the prediction of autoimmune diseases: Relevance of autoantibodies. Report on the 8th Dresden symposium on autoantibodies held in Dresden; 2007 September 12–15 Autoantigens, Autoantibodies, Autoimmunity, 5 2007. p 6–15.
   Google Scholar
• Vladutiu AO, Rose NR. Autoimmune murine thyroiditis. Relation to histocompatibility (H-2) type. Science 1971; 174: 1137–1139
   PubMed Web of Science ®Google Scholar
• Bacon LD, Kite JH, Jr., Rose NR. Relation between the major histocompatibility (B) locus and autoimmune thyroiditis in obese chickens. Science 1974; 186: 274–275
   PubMed Web of Science ®Google Scholar
• Rose NR, Kong YM, Sundick RS. The genetic lesions of autoimmunity. Clin Exp Immunol 1980; 39: 545–550
   PubMed Web of Science ®Google Scholar
• Burek CL, Hoffman WH, Rose NR. The presence of thyroid autoantibodies in children and adolescents with autoimmune thyroid disease and in their siblings and parents. Clin Immunol Immunopathol 1982; 25: 395–404
   PubMedGoogle Scholar
• Burek CL, Rose NR, Najar GM, Hoffman WH, Gimelfarb A, Zmijewski CM, Polesky HF, Hoffman WM. Autoimmune thyroid disease. Immunogenetics, GS Panayi, CS David. Butterworths, London 1984; 207–233, Chapter 9
   Google Scholar
• Rose NR, Burek CL. The interaction of basic science and population-based research: Autoimmune thyroiditis as a case history. Am J Epidemiol 1991; 134: 1073–1078
   PubMed Web of Science ®Google Scholar
• Gleason SL, Gearhart P, Rose NR, Kuppers RC. Autoantibodies to thyroglobulin are encoded by diverse V-gene segments and recognize restricted epitopes. J Immunol 1990; 145: 1768–1775
   PubMed Web of Science ®Google Scholar
• Beisel KW, Kong YM, Babu KSJ, David CS, Rose NR. Regulation of experimental autoimmune thyroiditis: Influence of non-H-2 genes. J Immunogenet 1992; 9: 257–265
   Google Scholar
• Zeitlin AA, Simmonds MJ, Gough SC. Genetic developments in autoimmune thyroid disease: An evolutionary process. Clin Endocrinol (Oxf) 2007, [E-Pub ahead of print]
   PubMed Web of Science ®Google Scholar
• Schott M, Eckstein A, Willenberg HS, Nguyen TB, Morgenthaler NG, Scherbaum WA. Improved prediction of relapse of Graves' thyrotoxicosis by combined determination of TSH receptor and thyroperoxidase antibodies. Horm Metab Res 2007; 39: 56–61
   PubMed Web of Science ®Google Scholar
• Premawardhana LD, Parkes AB, John R, Harris B, Lazarus JH. Thyroid peroxidase antibodies in early pregnancy: Utility for prediction of postpartum thyroid dysfunction and implications for screening. Thyroid 2004; 14: 610–615
   PubMed Web of Science ®Google Scholar
• Mamede da Costa S, Sieiro Netto L, Coeli CM, Buescu A, Vaisman M. Value of combined clinical information and thyroid peroxidase antibodies in pregnancy for the prediction of postpartum thyroid dysfunction. Am J Reprod Immunol 2007; 58: 344–349
   PubMed Web of Science ®Google Scholar
• Zois C, Stavrou I, Svarna E, Seferiadis K, Tsatsoulis A. Natural course of autoimmune thyroiditis after elimination of iodine deficiency in northwestern Greece. Thyroid 2006; 16: 289–293
   PubMed Web of Science ®Google Scholar
• Barker JM, Barriga KJ, Yu L, Miao D, Erlich HA, Norris JM, et al. Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes autoimmunity study in the young (DAISY). J Clin Endocrinol Metab 2004; 89: 3896–3902
   PubMed Web of Science ®Google Scholar
• Verge CF, Gianani R, Kawasaki E, Yu L, Pietropaolo M, Chase HP, et al. Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes. J Autoimmun 1996; 9: 379–383
   PubMed Web of Science ®Google Scholar
• Verge CF, Gianani R, Kawasaki E, Yu L, Pietropaolo M, Jackson RA, et al. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies. Diabetes 1996; 45: 926–933
   PubMed Web of Science ®Google Scholar
• Mrena S, Virtanen SM, Laippala P, Kulmala P, Hannila ML, Akerblom HK, et al. Models for predicting type 1 diabetes in siblings of affected children. Diabetes Care 2006; 29: 662–667
   PubMed Web of Science ®Google Scholar
• Siljander HT, Veijola R, Reunanen A, Virtanen SM, Akerblom HK, Knip M. Prediction of type 1 diabetes among siblings of affected children and in the general population. Diabetologia 2007; 50: 2272–2275
   PubMed Web of Science ®Google Scholar
• Hampe CS, Hall TR, Agren A, Rolandsson O. Longitudinal changes in epitope recognition of autoantibodies against glutamate decarboxylase 65 (GAD65Ab) in prediabetic adults developing diabetes. Clin Exp Immunol 2007; 148: 72–78
   PubMed Web of Science ®Google Scholar
• Sosenko JM, Krischer JP, Palmer JP, Mahon J, Cowie C, Greenbaum CJ, et al. A risk score for type 1 diabetes derived from autoantibody positive participants in the diabetes prevention trial- type 1. Diabetes Care 2008; 31: 528–533
   PubMed Web of Science ®Google Scholar
• Falorni A, Calcinaro F. Autoantibody profile and epitope mapping in latent autoimmune diabetes in adults. Ann N Y Acad Sci 2002; 958: 99–106
   PubMed Web of Science ®Google Scholar
• van Deutekom AW, Heine RJ, Simsek S. The islet autoantibody titres: Their clinical relevance in latent autoimmune diabetes in adults (LADA) and the classification of diabetes mellitus. Diabet Med 2008; 25: 117–125
   PubMed Web of Science ®Google Scholar
• Haller MJ, Gottlieb PA, Schatz DA. Type 1 diabetes intervention trials : Where are we and where are we going?. Curr Opin Endocrinol Diabetes Obes 2007; 14: 283–287
   PubMedGoogle Scholar
• Park H, Yu L, Kim T, Cho B, Kang J, Park Y. Antigenic determinants to GAD autoantibodies in patients with type 1 diabetes with and without autoimmune thyroid disease. Ann N Y Acad Sci 2006; 1079: 213–219
   PubMed Web of Science ®Google Scholar
• Burek CL, Rose NR, Guire KE, Hoffman WH. Thyroid autoantibodies in black and in white children and adolescents with type 1 diabetes mellitus and their first degree relatives. Autoimmunity 1990; 7: 157–167
   PubMed Web of Science ®Google Scholar
• Chang CC, Huang CN, Chuang LM. Autoantibodies to thyroid peroxidase in patients with type 1 diabetes in Taiwan. Eur J Endocrinol 1998; 139: 44–48
   PubMed Web of Science ®Google Scholar
• Maugendre D, Sonnet E, Derrien C, Le Golff MC, Grais MC, Allannic H, et al. Combined analysis of long-term anti-beta-cell humoral reactivity in type 1 diabetes with and without thyroid disease. Diabetes Metab 1999; 25: 28–33
   PubMed Web of Science ®Google Scholar
• Mantovani RM, Mantovani LM, Dias VM. Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus: Prevalence and risk factors. J Pediatr Endocrinol Metab 2007; 20: 669–675
   PubMed Web of Science ®Google Scholar
• De Block CE, De Leeuw IH, Decochez K, Winnock F, Van Autreve J, Van Campenhout CM, et al. The presence of thyrogastric antibodies in first degree relatives of type 1 diabetic patients is associated with age and proband antibody status. J Clin Endocrinol Metab 2001; 86: 4358–4363
   PubMed Web of Science ®Google Scholar
• Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349: 1526–1533
   PubMed Web of Science ®Google Scholar
• McClain MT, Arbuckle MR, Heinlen LD, Dennis GJ, Roebuck J, Rubertone MV, et al. The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus. Arthritis Rheum 2004; 50: 1226–1232
   PubMed Web of Science ®Google Scholar
• McClain MT, Heinlen LD, Dennis GJ, Roebuck J, Harley JB, James JA. Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. Nat Med 2005; 11: 85–89
   PubMed Web of Science ®Google Scholar
• James JA, Harley JB, Scofield RH. Epstein–Barr virus and systemic lupus erythematosus. Curr Opin Rheumatol 2006; 18: 462–467
   PubMed Web of Science ®Google Scholar
• Wandstrat AE, Carr-Johnson F, Branch V, Gray H, Fairhurst AM, Reimold A, et al. Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus. J Autoimmun 2006; 27: 153–160
   PubMed Web of Science ®Google Scholar
• Mahler M, Mierau R, Bluthner M. Fine-specificity of the anti-CENP-A B-cell autoimmune response. J Mol Med 2000; 78: 460–467
   PubMed Web of Science ®Google Scholar
• Akbarali Y, Matousek-Ronck J, Hunt L, Staudt L, Reichlin M, Guthridge JM, et al. Fine specificity mapping of autoantigens targeted by anti-centromere autoantibodies. J Autoimmun 2006; 27: 272–280
   PubMed Web of Science ®Google Scholar
• Korbet SM, Lewis EJ, Schwartz MM, Reichlin M, Evans J, Rohde RD. Factors predictive of outcome in severe lupus nephritis. Lupus Nephritis Collaborative Study Group. Am J Kidney Dis 2000; 35: 904–914
   PubMed Web of Science ®Google Scholar
• Scofield RH. Autoantibodies as predictors of disease. Lancet 2004; 363: 1544–1546
   PubMed Web of Science ®Google Scholar
• Bizzaro N. Autoantibodies as predictors of disease: The clinical and experimental evidence. Autoimmun Rev 2007; 6: 325–333
   PubMed Web of Science ®Google Scholar
• Notkins AL. New predictors of disease. Molecules called predictive autoantibodies appear in the blood years before people show symptoms of various disorders. Tests that detected these molecules could warn of the need to take preventive action. Sci Am 2007; 296: 72–79
   PubMed Web of Science ®Google Scholar
• Sihvonen S, Korpela M, Mustila A, Mustonen J. The predictive value of rheumatoid factor isotypes, anti-cyclic citrullinated peptide antibodies, and antineutrophil cytoplasmic antibodies for mortality in patients with rheumatoid arthritis. J Rheumatol 2005; 32: 2089–2094
   PubMed Web of Science ®Google Scholar
• Kudo-Tanaka E, Ohshima S, Ishii M, Mima T, Matsushita M, Azuma N, et al. Autoantibodies to cyclic citrullinated peptide 2 (CCP2) are superior to other potential diagnostic biomarkers for predicting rheumatoid arthritis in early undifferentiated arthritis. Clin Rheumatol 2007; 26: 1627–1633
   PubMed Web of Science ®Google Scholar
• Bukhari M, Thomson W, Naseem H, Bunn D, Silman A, Symmons D, et al. The performance of anti-cyclic citrullinated peptide antibodies in predicting the severity of radiologic damage in inflammatory polyarthritis: Results from the Norfolk arthritis register. Arthritis Rheum 2007; 56: 2929–2935
   PubMed Web of Science ®Google Scholar
• Mathsson L, Mullazehi M, Wick MC, Sjoberg O, van Vollenhoven R, Klareskog L, et al. Antibodies against citrullinated vimentin in rheumatoid arthritis: Higher sensitivity and extended prognostic value concerning future radiographic progression as compared with antibodies against cyclic citrullinated peptides. Arthritis Rheum 2008; 58: 36–45
   PubMed Web of Science ®Google Scholar
• Bobbio-Pallavicini F, Caporali R, Alpini C, Moratti R, Montecucco C. Predictive value of antibodies to citrullinated peptides and rheumatoid factors in anti-TNF-alpha treated patients. Ann N Y Acad Sci 2007; 1109: 287–295
   PubMed Web of Science ®Google Scholar
• Casquero P, Villoslada P, Montalban X, Torrent M. Frequency of multiple sclerosis in Menorca, Balearic islands, Spain. Neuroepidemiology 2001; 20: 129–133
   PubMed Web of Science ®Google Scholar
• Berger T, Rubner P, Schautzer F, Egg R, Ulmer H, Mayringer I, et al. Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event. N Engl J Med 2003; 349: 139–145
   PubMed Web of Science ®Google Scholar
• Kuhle J, Pohl C, Mehling M, Edan G, Freedman MS, Hartung HP, et al. Lack of association between antimyelin antibodies and progression to multiple sclerosis. N Engl J Med 2007; 356: 371–378
   PubMed Web of Science ®Google Scholar
• Pelayo R, Tintore M, Montalban X, Rovira A, Espejo C, Reindl M, et al. Antimyelin antibodies with no progression to multiple sclerosis. N Engl J Med 2007; 356: 426–428
   PubMed Web of Science ®Google Scholar
• Pittock SJ, Reindl M, Achenbach S, Berger T, Bruck W, Konig F, et al. Myelin oligodendrocyte glycoprotein antibodies in pathologically proven multiple sclerosis: Frequency, stability and clinicopathologic correlations. Mult Scler 2007; 13: 7–16
   PubMed Web of Science ®Google Scholar
• Lalive PH, Menge T, Delarasse C, Della Gaspera B, Pham-Dinh D, Villoslada P, et al. Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis. Proc Natl Acad Sci USA 2006; 103: 2280–2285
   PubMed Web of Science ®Google Scholar
• Beyer NH, Milthers J, Bonde Lauridsen AM, Houen G, Lautrup Frederiksen J. Autoantibodies to the proteasome in monosymptomatic optic neuritis may predict progression to multiple sclerosis. Scand J Clin Lab Invest 2007; 67: 696–706
   PubMed Web of Science ®Google Scholar
• Liu E, Li M, Emery L, Taki I, Barriga K, Tiberti C, et al. Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease. J Pediatr Gastroenterol Nutr 2007; 45: 293–300
   PubMed Web of Science ®Google Scholar
• Westerlund A, Ankelo M, Simell S, Ilonen J, Knip M, Simell O, et al. Affinity maturation of immunoglobulin A anti-tissue transglutaminase autoantibodies during development of coeliac disease. Clin Exp Immunol 2007; 148: 230–240
   PubMed Web of Science ®Google Scholar
• Bizzaro N, Tozzoli R, Shoenfeld Y. Are we at a stage to predict autoimmune rheumatic diseases?. Arthritis Rheum 2007; 56: 1736–1744
   PubMed Web of Science ®Google Scholar
• Caforio AL, Mahon NG, McKenna WJ. Clinical implications of anti-cardiac immunity in dilated cardiomyopathy. Ernst Schering Res Found Workshop 2006; 169–193
   PubMedGoogle Scholar
• Magnusson Y, Wallukat G, Waagstein F, Hjalmarson A, Hoebeke J. Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta 1-adrenoceptor with positive chronotropic effect. Circulation 1994; 89: 2760–2767
   PubMed Web of Science ®Google Scholar
• Stork S, Boivin V, Horf R, Hein L, Lohse MJ, Angermann CE, et al. Stimulating autoantibodies directed against the cardiac beta 1-adrenergic receptor predict increased mortality in idiopathic cardiomyopathy. Am Heart J 2006; 152: 697–704
   PubMed Web of Science ®Google Scholar
• Jahns R, Boivin V, Hein L, Triebel S, Angermann CE, Ertl G, et al. Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy. J Clin Invest 2004; 113: 1419–1429
   PubMed Web of Science ®Google Scholar
• Jahns R, Boivin V, Lohse MJ. Beta 1-adrenergic receptor-directed autoimmunity as a cause of dilated cardiomyopathy in rats. Int J Cardiol 2006; 112: 7–14
   PubMed Web of Science ®Google Scholar
• Rose NR, Wolfgram LJ, Herskowitz A, Beisel KW. Postinfectious autoimmunity: Two distinct phases of Coxsackievirus B3-induced myocarditis. Ann N Y Acad Sci 1986; 475: 146–156
   PubMed Web of Science ®Google Scholar
• Wolfgram LJ, Beisel KW, Herskowitz A, Rose NR. Variations in the susceptibility to Coxsackievirus B3-induced myocarditis among different strains of mice. J Immunol 1986; 136: 1846–1852
   PubMed Web of Science ®Google Scholar
• Herskowitz A, Beisel KW, Wolfgram LJ, Rose NR. Coxsackievirus B3 murine myocarditis: Wide pathologic spectrum in genetically defined inbred strains. Human Pathol 1985; 16: 671–673
   PubMed Web of Science ®Google Scholar
• Rose NR, Beisel KW, Herskowitz A, Neu N, Wolfgram LJ, Alvarez FL, Traystman MD, Craig SW. Cardiac myosin and autoimmune myocarditis. Autoimmunity and autoimmune disease. Ciba foundation symposium 129, D Evered, J Whelan. John Wiley & Sons, Ltd, Chichester, UK 1987; 3–24
   Google Scholar
• Wolfgram LJ, Beisel KW, Rose NR. Heart-specific autoantibodies following murine Coxsackievirus B3 myocarditis. J Exp Med 1985; 161: 1112–1121
   PubMed Web of Science ®Google Scholar
• Neu N, Beisel KW, Traystman MD, Rose NR, Craig SW. Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to Coxsackievirus B3-induced myocarditis. J Immunol 1987; 138: 2488–2492
   PubMed Web of Science ®Google Scholar
• Neu N, Rose NR, Beisel KW, Herskowitz A, Gurri-Glass G, Craig SW. Cardiac myosin induces myocarditis in genetically predisposed mice. J Immunol 1987; 139: 3630–3636
   PubMed Web of Science ®Google Scholar
• Rose NR, Neumann DA, Herskowitz A, Traystman MD, Beisel KW. Genetics of susceptibility to viral myocarditis in mice. Pathol Immunopathol Res 1988; 7: 266–278
   PubMedGoogle Scholar
• Guler ML, Ligons D, Rose NR. Genetics of autoimmune myocarditis. Immunogenetics of autoimmune disease, Joge Oksenberg, David Brassat. Landis Bioscience/Eurekah.com and Springer Science, Berlin 2005; 144–151
   Google Scholar
• Guler ML, Ligons DL, Wang Y, Bianco M, Broman KW, Rose NR. Two autoimmune diabetes loci influencing T cell apoptosis control susceptibility to experimental autoimmune myocarditis. J Immunol 2005; 174: 2167–2173
   PubMed Web of Science ®Google Scholar
• Eaton WW, Rose NR, Kalaydjian A, Pedersen MG, Mortensen PB. Epidemiology of autoimmune diseases in Denmark. J Autoimmun 2007; 29: 1–9
   PubMed Web of Science ®Google Scholar
• Fairweather DL, Rose NR. Inflammatory heart disease: A role for cytokines. Lupus 2005; 14: 1–6
   Web of Science ®Google Scholar
• Fairweather D, Rose NR. Coxsackievirus-induced myocaraditis in mice: A model of autoimmune disease for studying immunotoxicity. Methods 2007; 41: 118–122
   PubMed Web of Science ®Google Scholar
• Lane JR, Neumann DA, Lafond-Walker A, Herskowitz A, Rose NR. Role of IL-1 and tumor necrosis factor in Coxsackie virus-induced autoimmune myocarditis. J Immunol 1993; 151: 1682–1690
   PubMed Web of Science ®Google Scholar
• Neumann DA, Lane JR, Allen GS, Herskowitz A, Rose NR. Viral myocarditis leading to cardiomyopathy: Do cytokines contribute to pathogenesis?. Clin Immunol Immunopathol 1993; 68: 181–190
   PubMedGoogle Scholar
• Kaya Z, Afanasyeva M, Wang Y, Dohmen KM, Schlichting J, Tretter T, Fairweather D, Holers VM, Rose NR. Contribution of the innate immune system to autoimmune myocarditis: A role for complement. Nat Immunol 2001; 2: 739–745
   PubMed Web of Science ®Google Scholar
• Kaya Z, Rose NR. Innate immunity in experimental autoimmune myocarditis. Molecular autoimmunity, Moncef Zouali. Springer Science+Business Media, Inc., New York 2005; 1–12
   Google Scholar
• Afanasyeva M, Wang Y, Kaya Z, Stafford EA, Dohmen KM, Sadighi Akha AA, Rose NR. Interleukin-12 recepter/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-independent pathway. Circulation 2001; 104: 3145–3151
   PubMed Web of Science ®Google Scholar
• Afanasyeva M, Rose NR. Immune mediators in inflammatory heart disease: Insights from a mouse model. Eur Heart J 2002; 4(Suppl 1)131–146
   Google Scholar
• Rose NR, Afanasyeva M. The inflammatory process in experimental myocarditis. Inflammation and heart disease, GZ Feuerstein, P Libby, DL Mann. Birkhäuser Verlag, Basel 2003; 325–333
   Google Scholar
• Afanasyeva M, Georgakopoulos D, Rose NR. Autoimmune myocarditis: Cellular mediators of cardiac dysfunction. Autoimmun Rev 2004; 3: 476–486
   PubMed Web of Science ®Google Scholar
• Sharp V, Utz PJ. Technology insight: Can autoantibody profiling improve clinical practice?. Nat Clin Pract Rheumatol 2007; 3: 96–103
   PubMedGoogle Scholar
• Ahn AC, Tewari M, Poon CS, Phillips RS. The clinical applications of a systems approach. PLoS Med 2006; 3: e209
   Web of Science ®Google Scholar
• Shepshelovich D, Shoenfeld Y. Prediction and prevention of autoimmune diseases: Additional aspects of the mosaic of autoimmunity. Lupus 2006; 15: 183–190
   PubMed Web of Science ®Google Scholar