Association of established thyroid peroxidase autoantibody (TPOAb) genetic variants with Hashimoto’s thyroiditis

References

• Caturegli, P., A. De Remigis, and N. R. Rose. 2014. Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmun. Rev. 13: 391–397
   PubMed Web of Science ®Google Scholar
• Hollowell, J. G., N. W. Staehling, W. D. Flanders, et al. 2002. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National health and nutrition examination survey (NHANES III). J. Clin. Endocrinol. Metab. 87: 489–499
   PubMed Web of Science ®Google Scholar
• Zaletel, K., and S. Gaberscek. 2011. Hashimoto's thyroiditis: from genes to the disease. Curr. Genomics. 12: 576–588
   PubMed Web of Science ®Google Scholar
• Brix, T. H., K. O. Kyvik, K. Christensen, and L. Hegedus. 2001. Evidence for a major role of heredity in Graves' disease: a population-based study of two Danish twin cohorts. J. Clin. Endocrinol. Metab. 86: 930–934
   PubMed Web of Science ®Google Scholar
• Gough, S. C., and M. J. Simmonds. 2007. The HLA region and autoimmune disease: associations and mechanisms of action. Curr. Genomics. 8: 453–465
   PubMed Web of Science ®Google Scholar
• Ueda, H., J. M. Howson, L. Esposito, et al. 2003. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature. 423: 506–511
   PubMed Web of Science ®Google Scholar
• Velaga, M. R., V. Wilson, C. E. Jennings, et al. 2004. The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J. Clin. Endocrinol. Metab. 89: 5862–5865
   PubMed Web of Science ®Google Scholar
• Santos, L. R., C. Duraes, A. Mendes, et al. 2014. A polymorphism in the promoter region of the selenoprotein S gene (SEPS1) contributes to Hashimoto's thyroiditis susceptibility. J. Clin. Endocrinol. Metabol. 99: E719–E723
   PubMed Web of Science ®Google Scholar
• Li, M., B. Liu, L. Li, et al. 2015. Association studies of SEPS1 gene polymorphisms with Hashimoto's thyroiditis in Han Chinese. J. Hum. Genet. 60: 427–433
   PubMed Web of Science ®Google Scholar
• Lacka, K., A. Paradowska-Gorycka, A. Maciejewski, et al. 2014. Interleukin 1 beta (IL1beta) gene polymorphisms (SNP-511 and SNP + 3953) in Hashimoto's thyroiditis among the Polish population. Exp. Clin. Endocrinol. Diabetes. 122: 544–547
   PubMed Web of Science ®Google Scholar
• Oryoji, D., S. Ueda, K. Yamamoto, et al. 2015. Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease. J. Clin. Endocrinol. Metab. 100: E319–E324
   PubMed Web of Science ®Google Scholar
• Denny, J. C., D. C. Crawford, M. D. Ritchie, et al. 2011. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. Am. J. Hum. Genet. 89: 529–542
   PubMed Web of Science ®Google Scholar
• Eriksson, N., J. Y. Tung, A. K. Kiefer, et al. 2012. Novel associations for hypothyroidism include known autoimmune risk loci. PLoS One. 7: e34442
   PubMed Web of Science ®Google Scholar
• Plagnol, V., J. M. Howson, D. J. Smyth, et al. 2011. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet. 7: e1002216
   PubMed Web of Science ®Google Scholar
• Medici, M., E. Porcu, G. Pistis, et al. 2014. Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genet. 10: e1004123
   PubMed Web of Science ®Google Scholar
• Chu, X., C. M. Pan, S. X. Zhao, et al. 2011. A genome-wide association study identifies two new risk loci for Graves' disease. Nature. Genet. 43: 897–901
   PubMed Web of Science ®Google Scholar
• Zhao, S. X., L. Q. Xue, W. Liu, et al. 2013. Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Hum. Mol. Gen. 22: 3347–3362
   PubMed Web of Science ®Google Scholar
• Brix, T. H., L. Hegedus, A. Gardas, et al. 2011. Monozygotic twin pairs discordant for Hashimoto's thyroiditis share a high proportion of thyroid peroxidase autoantibodies to the immunodominant region A. Further evidence for genetic transmission of epitopic “fingerprints”. Autoimmunity. 44: 188–194
   PubMed Web of Science ®Google Scholar
• Huber, G., J. J. Staub, C. Meier, et al. 2002. Prospective study of the spontaneous course of subclinical hypothyroidism: prognostic value of thyrotropin, thyroid reserve, and thyroid antibodies. J. Clin. Endocrinol. Metab. 87: 3221–3226
   PubMed Web of Science ®Google Scholar
• Nielsen, C. H., T. H. Brix, R. G. Leslie, and L. Hegedus. 2009. A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase. Clin. Immunol. 133: 218–227
   PubMed Web of Science ®Google Scholar
• Pearce, E. N., A. P. Farwell, and L. E. Braverman. 2003. Thyroiditis. N. Engl. J. Med. 348: 2646–2655
   PubMed Web of Science ®Google Scholar
• Schweizer, U., J. Chiu, and J. Kohrle. 2008. Peroxides and peroxide-degrading enzymes in the thyroid. Antioxid. Redox. Signal. 10: 1577–1592
   PubMed Web of Science ®Google Scholar
• Zaletel, K. 2007. Determinants of thyroid autoantibody production in Hashimoto's thyroiditis. Expert Rev. Clin. Immunol. 3: 217–223
   PubMedGoogle Scholar
• Mariotti, S., P. Caturegli, P. Piccolo, et al. 1990. Antithyroid peroxidase autoantibodies in thyroid diseases. J. Clin. Endocrinol. Metab. 71: 661–669
   PubMed Web of Science ®Google Scholar
• Rudan, I., A. Marusic, S. Jankovic, et al. 2009. “10001 Dalmatians:” Croatia launches its national biobank. Croat. Med. J. 50: 4–6
   PubMed Web of Science ®Google Scholar
• Seeb, J. E., C. E. Pascal, R. Ramakrishnan, and L. W. Seeb. 2009. SNP genotyping by the 5'-nuclease reaction: advances in high-throughput genotyping with nonmodel organisms. Methods Mol. Biol. 578: 277–292
   PubMedGoogle Scholar
• Purcell, S., B. Neale, K. Todd-Brown, et al. 2007. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81: 559–575
   PubMed Web of Science ®Google Scholar
• Gauderman, W. J. 2003. Candidate gene association analysis for a quantitative trait, using parent-offspring trios. Genet. Epidemiol. 25: 327–338
   PubMed Web of Science ®Google Scholar
• Auburger, G., S. Gispert, S. Lahut, et al. 2014. 12q24 locus association with type 1 diabetes: SH2B3 or ATXN2? World J. Diabetes. 5: 316–327
   PubMedGoogle Scholar
• Yamashita, C., H. Tomiyama, M. Funayama, et al. 2014. Evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease. Neurobiol. Aging. 35: 1779e1717–1721
   Web of Science ®Google Scholar
• Kullo, I. J., K. Shameer, H. Jouni, et al. 2014. The ATXN2-SH2B3 locus is associated with peripheral arterial disease: an electronic medical record-based genome-wide association study. Front. Genet. 5: 166
   PubMedGoogle Scholar
• Ganesh, S. K., V. Tragante, W. Guo, et al. 2013. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum. Mol. Genet. 22: 1663–1678
   PubMed Web of Science ®Google Scholar
• Hinks, A., P. Martin, E. Flynn, et al.Worthington, and W. Thomson. 2010. Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis. Ann. Rheum. Dis. 69: 2169–2172
   PubMed Web of Science ®Google Scholar
• Kus, A., K. Szymanski, R. P. Peeters, et al. 2014. The association of thyroid peroxidase antibody risk loci with susceptibility to and phenotype of Graves' disease. Clin. Endocrinol 83: 556–562
   PubMed Web of Science ®Google Scholar
• Strieder, T. G., M. F. Prummel, J. G. Tijssen, et al. 2003. Risk factors for and prevalence of thyroid disorders in a cross-sectional study among healthy female relatives of patients with autoimmune thyroid disease. Clin. Endocrinol. 59: 396–401
   PubMed Web of Science ®Google Scholar
• Barrett, J. C., D. G. Clayton, P. Concannon, et al. 2009. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nature Genet. 41: 703–707
   PubMed Web of Science ®Google Scholar
• Dubois, P. C., G. Trynka, L. Franke, et al. 2010. Multiple common variants for celiac disease influencing immune gene expression. Nature Genet. 42: 295–302
   PubMed Web of Science ®Google Scholar
• Jin, Y., S. A. Birlea, P. R. Fain, et al. 2012. Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. Nature. Genet. 44: 676–680
   PubMed Web of Science ®Google Scholar
• Stahl, E. A., S. Raychaudhuri, E. F. Remmers, et al. 2010. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nature Genet. 42: 508–514
   PubMed Web of Science ®Google Scholar
• Bakker, B., H. Bikker, T. Vulsma, et al. 2000. Two decades of screening for congenital hypothyroidism in The Netherlands: TPO gene mutations in total iodide organification defects (an update). J. Clin. Endocrinol. Metab. 85: 3708–3712
   PubMed Web of Science ®Google Scholar
• Abramowicz, M. J., H. M. Targovnik, V. Varela, et al. 1992. Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter. J. Clin. Investig. 90: 1200–1204
   PubMed Web of Science ®Google Scholar
• Fuller, D. M., M. Zhu, X. Song, et al. 2012. Regulation of RasGRP1 function in T cell development and activation by its unique tail domain. PLoS One. 7: e38796
   PubMed Web of Science ®Google Scholar
• Dorr, H. G., M. Bettendorf, G. Binder, et al. 2015. Levothyroxine treatment of euthyroid children with autoimmune Hashimoto thyroiditis: results of a multicenter, randomized, controlled trial. Horm. Res. Paediatr. 84: 266–274
   PubMed Web of Science ®Google Scholar
• Sweeney, L. B., C. Stewart, and D. Y. Gaitonde. 2014. Thyroiditis: an integrated approach. Am. Fam. Phys. 90: 389–396
   PubMed Web of Science ®Google Scholar
• Qu, H. Q., S. F. Grant, J. P. Bradfield, et al. 2009. Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies. J. Med. Genet. 46: 553–554
   PubMed Web of Science ®Google Scholar
• Li, J. Y., F. Tao, X. X. Wu, et al. 2015. Common RASGRP1 gene variants that confer risk of type 2 diabetes. Genet. Test. Mol. Biomarkers. 19: 439–443
   PubMed Web of Science ®Google Scholar
• van de Graaf, S. A., C. Ris-Stalpers, E. Pauws, et al. 2001. Up to date with human thyroglobulin. J. Endocrinol. 170: 307–321
   PubMed Web of Science ®Google Scholar
• McLachlan, S. M., and B. Rapoport. 2004. Why measure thyroglobulin autoantibodies rather than thyroid peroxidase autoantibodies? Thyroid. 14: 510–520
   PubMed Web of Science ®Google Scholar
• Jabrocka-Hybel, A., A. Skalniak, J. Piatkowski, et al. 2013. How far are we from understanding the genetic basis of Hashimoto's thyroiditis? Int. Rev. Immunol. 32: 337–354
   PubMed Web of Science ®Google Scholar