Interleukin-6-174G > C (rs1800795) polymorphism distribution and its association with rheumatoid arthritis: A case-control study and meta-analysis

References

• McInnes, I. B., and G. Schett. 2011. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365: 2205–2219
   PubMed Web of Science ®Google Scholar
• Kvien, T. K., A. Glennas, O. G. Knudsrod, et al 1997. The prevalence and severity of rheumatoid arthritis in Oslo. Results from a county register and a population survey. Scand. J. Rheumatol. 26: 412–418
   PubMed Web of Science ®Google Scholar
• Klareskog, L., L. Padyukov, J. Lorentzen, and L. Alfredsson. 2006. Mechanisms of disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis. Nat. Clin. Pract. Rheumatol. 2: 425–433
   PubMedGoogle Scholar
• Perricone, C., F. Ceccarelli, and G. Valesini. 2011. An overview on the genetic of rheumatoid arthritis: a never-ending story. Autoimmun. Rev. 10: 599–608
   PubMed Web of Science ®Google Scholar
• Okada, Y., D. Wu, T. Trynka, et al 2014. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506: 376–381
   PubMed Web of Science ®Google Scholar
• MacGregor, A. J., H. Snieder, A. S. Rigby, et al 2000. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis. Rheum. 43: 30–37
   PubMed Web of Science ®Google Scholar
• Eyre, S., J. Bowes, D. Diogo, et al 2012. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genet. 44: 1336–1340
   PubMed Web of Science ®Google Scholar
• Li, Y., and A. B. Begovich. 2009. Unraveling the genetics of complex diseases: susceptibility genes for rheumatoid arthritis and psoriasis. Semin. Immunol. 21: 318–327
   PubMed Web of Science ®Google Scholar
• Suzuki, T., K. Ikari, K. Yano, et al 2013. PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study. PLoS One. 8: e61045
   PubMed Web of Science ®Google Scholar
• Stahl, E. A., S. Raychaudhuri, E. F. Remmers, et al 2010. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat. Genet. 42: 508–514
   PubMed Web of Science ®Google Scholar
• Nile, C. J., R. C. Read, M. Akil, et al 2008. Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum. 58: 2686–2693
   PubMed Web of Science ®Google Scholar
• Furst, D. E., and P. Emery. 2014. Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets. Rheumatology (Oxford). 53: 1560–1569
   PubMed Web of Science ®Google Scholar
• Yoshizaki, K., N. Nishimoto, M. Mihara, and T. Kishimoto. 1998. Therapy of rheumatoid arthritis by blocking IL-6 signal transduction with a humanized anti-IL-6 receptor antibody. Springer Semin. Immunopathol. 20: 247–259
   PubMed Web of Science ®Google Scholar
• Lipsky, P. E. 2006. Interleukin-6 and rheumatic diseases. Arthritis Res. Ther. 8: S4
   PubMed Web of Science ®Google Scholar
• Suematsu, S., T. Matsuda, and K. Aozasaetal. 1989. IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc. Natl. Acad. Sci. USA. 86: 7547–7551
   PubMed Web of Science ®Google Scholar
• Rincon, M., J. Anguita, T. Nakamura, et al 1997. Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J. Exp. Med. 185: 461–469
   PubMed Web of Science ®Google Scholar
• Maggio, M., J. M. Guralnik, D. L. Longo, and L. Ferrucci. 2006. Interleukin-6 in aging and chronic disease: a magnificent pathway. J. Gerontol. A Biol. Sci. Med. Sci. 61: 575–584
   PubMed Web of Science ®Google Scholar
• Marinou, I., J. Healy, D. Mewar, et al 2007. Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status. Arthritis Rheum. 56: 2549–2556
   PubMed Web of Science ®Google Scholar
• Li, X., W. Chai, M. Ni, et al 2014. The effects of gene polymorphisms in interleukin-4 and interleukin-6 on the susceptibility of rheumatoid arthritis in a Chinese population. Biomed. Res. Int. 2014: 265435
   PubMed Web of Science ®Google Scholar
• Li, F., J. Xu, J. Zheng, et al 2014. Association between interleukin-6 gene polymorphisms and rheumatoid arthritis in Chinese Han population: a case-control study and a meta-analysis. Sci. Rep. 4: 5714
   PubMed Web of Science ®Google Scholar
• Shafia, S., F. A. Dilafroze, R. Sofi, et al 2014. Rheumatoid arthritis and genetic variations in cytokine genes: a population-based study in Kashmir Valley. Immunol. Invest. 43: 349–359
   PubMed Web of Science ®Google Scholar
• Zavaleta-Muniz, S. A., B. T. Martín-Márquez, L. Gonzalez-Lopez, et al 2013. The -174G/C and -572G/C interleukin 6 promoter gene polymorphisms in Mexican patients with rheumatoid arthritis: a case-control study. Clin. Dev. Immunol. 2013: 959084
   PubMedGoogle Scholar
• You, C. G., X. J. Li, Y. M. Li, et al 2013. Association analysis of single nucleotide polymorphisms of proinflammatory cytokine and their receptors genes with rheumatoid arthritis in northwest Chinese Han population. Cytokine. 61: 133–138
   PubMed Web of Science ®Google Scholar
• Arman, A., A. Coker, O. Sarioz, et al 2012. Lack of association between IL-6 gene polymorphisms and rheumatoid arthritis in Turkish population. Rheumatol. Int. 32: 2199–2201
   PubMed Web of Science ®Google Scholar
• Emonts, M., M. J. Hazes, J. J. Houwing-Duistermaat, et al 2011. Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study. BMC Med. Genet. 12: 36
   PubMed Web of Science ®Google Scholar
• Trajkov, D., S. Mishevska-Perchinkova, A. Karadzova-Stojanoska, et al 2009. Association of 22 cytokine gene polymorphisms with rheumatoid arthritis in population of ethnic Macedonians. Clin. Rheumatol. 28: 1291–1300
   PubMed Web of Science ®Google Scholar
• Palomino-Morales, R., C. Gonzalez-Juanatey, T. R. Vazquez-Rodriguez, et al 2009. Interleukin-6 gene -174 promoter polymorphism is associated with endothelial dysfunction but not with disease susceptibility in patients with rheumatoid arthritis. Clin. Exp. Rheumatol. 27: 964–970
   PubMed Web of Science ®Google Scholar
• Panoulas, V. F., A. Stavropoulos-Kalinoglou, G. S. Metsios, et al 2009. Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: the role of obesity and smoking. Atherosclerosis. 204: 178–183
   PubMed Web of Science ®Google Scholar
• Huang, X. Z., J. H. Zhuang, Y. G. Ren, et al 2007. Association of interleukin-6 and interleukin-18 gene polymorphism with rheumatoid arthritis in Guangdong Han population. Nan Fang Yi Ke Da Xue Xue Bao. 27: 1661–1664
   PubMedGoogle Scholar
• Pawlik, A., J. Wrzesniewska, M. Florczak, et al 2005. IL-6 promoter polymorphism in patients with rheumatoid arthritis. Scand. J. Rheumatol. 34: 109–113
   Google Scholar
• Dar, S. A., N. Akhter, S. Haque, et al 2016. Tumor necrosis factor (TNF)-α -308G/A (rs1800629) polymorphism distribution in north India and its association with pemphigus: case-control study and meta-analysis. Autoimmunity. 13: 1–9
   Google Scholar
• Purcell, S., S. S. Cherny, and P. C. Sham. 2003. Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics. 19: 149–150
   PubMed Web of Science ®Google Scholar
• Panic, N., E. Leoncini, G. de Belvis, et al 2013. Evaluation of the endorsement of the preferred reporting items for systematic reviews and meta-analysis (PRISMA) statement on the quality of published systematic review and meta-analyses. PLoS One. 8: e83138
   PubMed Web of Science ®Google Scholar
• Wu, R., and B. Li. 1999. A multiplicative-epistatic model for analyzing interspecific differences in outcrossing species. Biometrics. 55: 355–365
   PubMed Web of Science ®Google Scholar
• DerSimonian, R., and N. Laird. 1986. Meta-analysis in clinical trials. Control Clin. Trials. 7: 177–188
   PubMed Web of Science ®Google Scholar
• Mantel, N., and W. Haenszel. 1959. Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst. 22: 719–748
   PubMed Web of Science ®Google Scholar
• Higgins, J. P., S. G. Thompson, J. J. Deeks, and D. G. Altman. 2003. Measuring inconsistency in meta-analyses. BMJ. 327: 557–560
   PubMed Web of Science ®Google Scholar
• Egger, M., G. Davey-Smith, M. Schneider, and C. Minder. 1997. Bias in meta-analysis detected by a simple, graphical test. BMJ. 315: 629–634
   PubMed Web of Science ®Google Scholar
• Yang, B., J. Chen, Y. Li, et al 2012. Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population. Hum. Immunol. 73: 101–106
   PubMed Web of Science ®Google Scholar
• Wei, S. T., Y. H. Sun, S. H. Zong, and Y. B. Xiang. 2015. Serum levels of IL-6 and TNF-α may correlate with activity and severity of rheumatoid arthritis. Med. Sci. Monit. 21: 4030–4038
   PubMed Web of Science ®Google Scholar
• Lee, Y. H., S. C. Bae, S. J. Choi, et al 2012. The association between interleukin-6 polymorphisms and rheumatoid arthritis: a meta-analysis. Inflamm. Res. 61: 665–671
   PubMed Web of Science ®Google Scholar
• Fishman, D., G. Faulds, R. Jeffery, et al 1998. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J. Clin. Invest. 102: 1369–1376
   PubMed Web of Science ®Google Scholar
• Hoffmann, S. C., E. M. Stanley, E. Darrin Cox, et al 2001. Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes. Transplantation. 72: 1444–1450
   PubMed Web of Science ®Google Scholar
• Oen, K., P. N. Malleson, D. A. Cabral, et al 2005. Cytokine genotypes correlate with pain and radiologically defined joint damage in patients with juvenile rheumatoid arthritis. Rheumatology (Oxford). 44: 1115–1121
   PubMed Web of Science ®Google Scholar